UNITED THERAPEUTICS CORP DEL

Ticker: UTHR CUSIP: 91307C102 Class: EQTY

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015

Shares 28,840 Value ($000) $3,785 Avg Close $160.39 Range $129.48 - $181.03

Q2 2015

Shares 28,840 Value ($000) $5,017 Avg Close $179.89 Range $157.20 - $190.29

Q1 2015

Shares 48,840 Value ($000) $8,422 Avg Close $152.45 Range $124.21 - $181.61

Q4 2014

Shares 73,840 Value ($000) $9,562 Avg Close $128.87 Range $118.47 - $137.84

Q3 2014

Shares 88,840 Value ($000) $11,429 Avg Close $103.09 Range $86.04 - $136.93

Q1 2014

Shares 50,000 Value ($000) $4,702 Avg Close $102.28 Range $87.94 - $115.00

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2015	28,840	$3,785	$160.39	$129.48 - $181.03
Q2 2015	28,840	$5,017	$179.89	$157.20 - $190.29
Q1 2015	48,840	$8,422	$152.45	$124.21 - $181.61
Q4 2014	73,840	$9,562	$128.87	$118.47 - $137.84
Q3 2014	88,840	$11,429	$103.09	$86.04 - $136.93
Q1 2014	50,000	$4,702	$102.28	$87.94 - $115.00