UPSTREAM BIO INC

Ticker: UPB CUSIP: 91678A107 Class: Common Stock

Verition Fund Management LLC's Holding History (CIK: 0001454027)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 12,020 Value ($000) $326 Avg Close $24.89 Range $18.05 - $33.00

Q3 2025

Shares 47,001 Value ($000) $884 Avg Close $15.54 Range $10.54 - $21.03

Q2 2025

Shares 33,505 Value ($000) $368 Avg Close $9.24 Range $5.14 - $12.10

Q4 2024

Shares 37,379 Value ($000) $615 Avg Close $22.33 Range $14.97 - $29.46

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	12,020	$326	$24.89	$18.05 - $33.00
Q3 2025	47,001	$884	$15.54	$10.54 - $21.03
Q2 2025	33,505	$368	$9.24	$5.14 - $12.10
Q4 2024	37,379	$615	$22.33	$14.97 - $29.46