UPSTREAM BIO INC

Ticker: UPB CUSIP: 91678A107 Class: Common Stock

Exome Asset Management LLC's Holding History (CIK: 0002011932)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 64,845 Value ($000) $1,761 Avg Close $24.89 Range $18.05 - $33.00

Q3 2025

Shares 51,960 Value ($000) $977 Avg Close $15.54 Range $10.54 - $21.03

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	64,845	$1,761	$24.89	$18.05 - $33.00
Q3 2025	51,960	$977	$15.54	$10.54 - $21.03