VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS's Holding History (CIK: 0001083190)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 59,016 Value ($000) $26,755 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 61,569 Value ($000) $24,113 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 62,981 Value ($000) $28,039 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 58,725 Value ($000) $28,471 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 54,758 Value ($000) $22,051 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 56,186 Value ($000) $26,131 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 56,682 Value ($000) $26,568 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 56,573 Value ($000) $23,648 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 56,429 Value ($000) $22,960 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 51,895 Value ($000) $18,046 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 44,918 Value ($000) $15,807 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 43,583 Value ($000) $13,732 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 43,390 Value ($000) $13 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 37,512 Value ($000) $10,861 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 37,238 Value ($000) $10,493 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 34,063 Value ($000) $8,889 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 31,913 Value ($000) $7,008 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 32,511 Value ($000) $5,897 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 32,433 Value ($000) $6,539 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 32,513 Value ($000) $6,987 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 32,492 Value ($000) $7,679 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 24,133 Value ($000) $6,567 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 14,826 Value ($000) $4,304 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 16,429 Value ($000) $3,909 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 16,560 Value ($000) $3,626 Avg Close $202.38 Range $165.23 - $225.66

Q3 2019

Shares 16,471 Value ($000) $2,791 Avg Close $176.91 Range $165.27 - $188.44

Q2 2019

Shares 19,868 Value ($000) $3,643 Avg Close $174.82 Range $163.68 - $191.71

Q1 2019

Shares 14,946 Value ($000) $2,749 Avg Close $184.70 Range $160.95 - $195.81

Q4 2018

Shares 13,942 Value ($000) $2,310 Avg Close $173.27 Range $151.80 - $194.92

Q3 2018

Shares 20,972 Value ($000) $4,042 Avg Close $178.07 Range $164.70 - $193.78

Q2 2018

Shares 26,676 Value ($000) $4,534 Avg Close $155.01 Range $144.07 - $172.00

Q1 2018

Shares 22,719 Value ($000) $3,703 Avg Close $163.34 Range $146.21 - $178.15

Q4 2017

Shares 22,622 Value ($000) $3,390 Avg Close $148.07 Range $136.50 - $158.04

Q3 2017

Shares 20,504 Value ($000) $3,117 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 18,504 Value ($000) $2,385 Avg Close $120.38 Range $107.24 - $137.26

Q1 2017

Shares 18,429 Value ($000) $2,015 Avg Close $88.04 Range $73.34 - $111.88

Q4 2016

Shares 14,218 Value ($000) $1,047 Avg Close $81.37 Range $71.46 - $97.93

Q3 2016

Shares 14,151 Value ($000) $1,234 Avg Close $94.50 Range $83.50 - $103.73

Q2 2016

Shares 19,805 Value ($000) $1,704 Avg Close $86.41 Range $75.92 - $96.49

Q1 2016

Shares 18,284 Value ($000) $1,453 Avg Close $90.45 Range $75.90 - $124.96

Q4 2015

Shares 16,054 Value ($000) $2,020 Avg Close $120.72 Range $101.49 - $134.71

Q3 2015

Shares 15,719 Value ($000) $1,637 Avg Close $128.47 Range $97.45 - $143.45

Q2 2015

Shares 27,372 Value ($000) $3,380 Avg Close $125.98 Range $113.68 - $137.50

Q1 2015

Shares 27,773 Value ($000) $3,276 Avg Close $119.81 Range $103.75 - $136.33

Q4 2014

Shares 43,886 Value ($000) $5,214 Avg Close $112.63 Range $96.43 - $124.35

Q3 2014

Shares 43,664 Value ($000) $4,904 Avg Close $95.21 Range $84.41 - $116.88

Q2 2014

Shares 43,260 Value ($000) $4,096 Avg Close $70.12 Range $59.79 - $98.80

Q1 2014

Shares 45,172 Value ($000) $3,195 Avg Close $79.20 Range $67.49 - $87.77

Q4 2013

Shares 44,617 Value ($000) $3,315 Avg Close $69.64 Range $58.06 - $78.38

Q3 2013

Shares 47,547 Value ($000) $3,605 Avg Close $79.58 Range $73.43 - $89.96

Q2 2013

Shares 31,506 Value ($000) $2,522 Avg Close $73.64 Range $51.28 - $87.47

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	59,016	$26,755	$431.03	$392.50 - $464.44
Q3 2025	61,569	$24,113	$417.92	$362.50 - $484.56
Q2 2025	62,981	$28,039	$460.83	$416.60 - $510.77
Q1 2025	58,725	$28,471	$466.00	$397.25 - $519.68
Q4 2024	54,758	$22,051	$463.53	$377.85 - $519.88
Q3 2024	56,186	$26,131	$480.37	$456.07 - $510.64
Q2 2024	56,682	$26,568	$434.05	$391.01 - $486.43
Q1 2024	56,573	$23,648	$422.74	$403.43 - $448.40
Q4 2023	56,429	$22,960	$369.42	$341.85 - $413.00
Q3 2023	51,895	$18,046	$349.73	$335.82 - $367.00
Q2 2023	44,918	$15,807	$336.94	$313.47 - $354.94
Q1 2023	43,583	$13,732	$299.93	$282.21 - $325.19
Q4 2022	43,390	$13	$304.77	$283.58 - $324.75
Q3 2022	37,512	$10,861	$287.72	$271.61 - $305.95
Q2 2022	37,238	$10,493	$267.66	$233.01 - $293.17
Q1 2022	34,063	$8,889	$237.33	$214.66 - $263.58
Q4 2021	31,913	$7,008	$194.45	$176.36 - $224.49
Q3 2021	32,511	$5,897	$195.24	$180.02 - $204.88
Q2 2021	32,433	$6,539	$209.17	$185.33 - $222.78
Q1 2021	32,513	$6,987	$219.65	$204.62 - $242.99
Q4 2020	32,492	$7,679	$229.44	$202.57 - $280.99
Q3 2020	24,133	$6,567	$275.88	$253.97 - $306.08
Q2 2020	14,826	$4,304	$271.12	$222.39 - $299.21
Q1 2020	16,429	$3,909	$229.39	$197.47 - $249.85
Q4 2019	16,560	$3,626	$202.38	$165.23 - $225.66
Q3 2019	16,471	$2,791	$176.91	$165.27 - $188.44
Q2 2019	19,868	$3,643	$174.82	$163.68 - $191.71
Q1 2019	14,946	$2,749	$184.70	$160.95 - $195.81
Q4 2018	13,942	$2,310	$173.27	$151.80 - $194.92
Q3 2018	20,972	$4,042	$178.07	$164.70 - $193.78
Q2 2018	26,676	$4,534	$155.01	$144.07 - $172.00
Q1 2018	22,719	$3,703	$163.34	$146.21 - $178.15
Q4 2017	22,622	$3,390	$148.07	$136.50 - $158.04
Q3 2017	20,504	$3,117	$150.51	$125.50 - $167.86
Q2 2017	18,504	$2,385	$120.38	$107.24 - $137.26
Q1 2017	18,429	$2,015	$88.04	$73.34 - $111.88
Q4 2016	14,218	$1,047	$81.37	$71.46 - $97.93
Q3 2016	14,151	$1,234	$94.50	$83.50 - $103.73
Q2 2016	19,805	$1,704	$86.41	$75.92 - $96.49
Q1 2016	18,284	$1,453	$90.45	$75.90 - $124.96
Q4 2015	16,054	$2,020	$120.72	$101.49 - $134.71
Q3 2015	15,719	$1,637	$128.47	$97.45 - $143.45
Q2 2015	27,372	$3,380	$125.98	$113.68 - $137.50
Q1 2015	27,773	$3,276	$119.81	$103.75 - $136.33
Q4 2014	43,886	$5,214	$112.63	$96.43 - $124.35
Q3 2014	43,664	$4,904	$95.21	$84.41 - $116.88
Q2 2014	43,260	$4,096	$70.12	$59.79 - $98.80
Q1 2014	45,172	$3,195	$79.20	$67.49 - $87.77
Q4 2013	44,617	$3,315	$69.64	$58.06 - $78.38
Q3 2013	47,547	$3,605	$79.58	$73.43 - $89.96
Q2 2013	31,506	$2,522	$73.64	$51.28 - $87.47