VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

GREAT POINT PARTNERS LLC's Holding History (CIK: 0001281446)

Note: Option positions (PUT/CALL) are excluded.

Q1 2022

Shares 85,000 Value ($000) $22,182 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 85,000 Value ($000) $18,666 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 85,000 Value ($000) $15,418 Avg Close $195.24 Range $180.02 - $204.88

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2022	85,000	$22,182	$237.33	$214.66 - $263.58
Q4 2021	85,000	$18,666	$194.45	$176.36 - $224.49
Q3 2021	85,000	$15,418	$195.24	$180.02 - $204.88