VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Redmile Group, LLC's Holding History (CIK: 0001425738)

Note: Option positions (PUT/CALL) are excluded.

Q3 2017

Shares 189,008 Value ($000) $28,737 Avg Close $150.51 Range $125.50 - $167.86

Q2 2017

Shares 144,408 Value ($000) $18,610 Avg Close $120.38 Range $107.24 - $137.26

Q3 2013

Shares 108,262 Value ($000) $8,208 Avg Close $79.58 Range $73.43 - $89.96

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2017	189,008	$28,737	$150.51	$125.50 - $167.86
Q2 2017	144,408	$18,610	$120.38	$107.24 - $137.26
Q3 2013	108,262	$8,208	$79.58	$73.43 - $89.96