VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

EXCHANGE TRADED CONCEPTS, LLC's Holding History (CIK: 0001457320)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 12,025 Value ($000) $5,452 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 10,151 Value ($000) $3,976 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 2,586 Value ($000) $1,151 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 2,623 Value ($000) $1,272 Avg Close $466.00 Range $397.25 - $519.68

Q4 2024

Shares 2,945 Value ($000) $1,186 Avg Close $463.53 Range $377.85 - $519.88

Q3 2024

Shares 2,958 Value ($000) $1,376 Avg Close $480.37 Range $456.07 - $510.64

Q2 2024

Shares 5,313 Value ($000) $2,490 Avg Close $434.05 Range $391.01 - $486.43

Q1 2024

Shares 5,441 Value ($000) $2,274 Avg Close $422.74 Range $403.43 - $448.40

Q4 2023

Shares 7,759 Value ($000) $3,157 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 9,130 Value ($000) $3,175 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 8,331 Value ($000) $2,932 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 10,257 Value ($000) $3,232 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 8,496 Value ($000) $2,453 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 10,886 Value ($000) $3,152 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 11,753 Value ($000) $3,312 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 14,052 Value ($000) $3,667 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 12,110 Value ($000) $2,659 Avg Close $194.45 Range $176.36 - $224.49

Q3 2021

Shares 15,456 Value ($000) $2,804 Avg Close $195.24 Range $180.02 - $204.88

Q2 2021

Shares 26,673 Value ($000) $5,378 Avg Close $209.17 Range $185.33 - $222.78

Q1 2021

Shares 11,007 Value ($000) $2,365 Avg Close $219.65 Range $204.62 - $242.99

Q4 2020

Shares 6,875 Value ($000) $1,625 Avg Close $229.44 Range $202.57 - $280.99

Q3 2020

Shares 2,407 Value ($000) $655 Avg Close $275.88 Range $253.97 - $306.08

Q2 2020

Shares 1,348 Value ($000) $391 Avg Close $271.12 Range $222.39 - $299.21

Q1 2020

Shares 529 Value ($000) $126 Avg Close $229.39 Range $197.47 - $249.85

Q4 2019

Shares 428 Value ($000) $94 Avg Close $202.38 Range $165.23 - $225.66

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	12,025	$5,452	$431.03	$392.50 - $464.44
Q3 2025	10,151	$3,976	$417.92	$362.50 - $484.56
Q2 2025	2,586	$1,151	$460.83	$416.60 - $510.77
Q1 2025	2,623	$1,272	$466.00	$397.25 - $519.68
Q4 2024	2,945	$1,186	$463.53	$377.85 - $519.88
Q3 2024	2,958	$1,376	$480.37	$456.07 - $510.64
Q2 2024	5,313	$2,490	$434.05	$391.01 - $486.43
Q1 2024	5,441	$2,274	$422.74	$403.43 - $448.40
Q4 2023	7,759	$3,157	$369.42	$341.85 - $413.00
Q3 2023	9,130	$3,175	$349.73	$335.82 - $367.00
Q2 2023	8,331	$2,932	$336.94	$313.47 - $354.94
Q1 2023	10,257	$3,232	$299.93	$282.21 - $325.19
Q4 2022	8,496	$2,453	$304.77	$283.58 - $324.75
Q3 2022	10,886	$3,152	$287.72	$271.61 - $305.95
Q2 2022	11,753	$3,312	$267.66	$233.01 - $293.17
Q1 2022	14,052	$3,667	$237.33	$214.66 - $263.58
Q4 2021	12,110	$2,659	$194.45	$176.36 - $224.49
Q3 2021	15,456	$2,804	$195.24	$180.02 - $204.88
Q2 2021	26,673	$5,378	$209.17	$185.33 - $222.78
Q1 2021	11,007	$2,365	$219.65	$204.62 - $242.99
Q4 2020	6,875	$1,625	$229.44	$202.57 - $280.99
Q3 2020	2,407	$655	$275.88	$253.97 - $306.08
Q2 2020	1,348	$391	$271.12	$222.39 - $299.21
Q1 2020	529	$126	$229.39	$197.47 - $249.85
Q4 2019	428	$94	$202.38	$165.23 - $225.66