VERTEX PHARMACEUTICALS INC

Ticker: VRTX CUSIP: 92532F100 Class: EQTY

Privium Fund Management B.V.'s Holding History (CIK: 0001795097)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 9,355 Value ($000) $4,241 Avg Close $431.03 Range $392.50 - $464.44

Q3 2025

Shares 8,300 Value ($000) $3,251 Avg Close $417.92 Range $362.50 - $484.56

Q2 2025

Shares 8,300 Value ($000) $3,753 Avg Close $460.83 Range $416.60 - $510.77

Q1 2025

Shares 8,300 Value ($000) $4,024 Avg Close $466.00 Range $397.25 - $519.68

Q4 2023

Shares 15,116 Value ($000) $6,211 Avg Close $369.42 Range $341.85 - $413.00

Q3 2023

Shares 21,395 Value ($000) $7,440 Avg Close $349.73 Range $335.82 - $367.00

Q2 2023

Shares 30,910 Value ($000) $10,762 Avg Close $336.94 Range $313.47 - $354.94

Q1 2023

Shares 32,470 Value ($000) $10,230 Avg Close $299.93 Range $282.21 - $325.19

Q4 2022

Shares 35,307 Value ($000) $10,207 Avg Close $304.77 Range $283.58 - $324.75

Q3 2022

Shares 28,500 Value ($000) $8,345 Avg Close $287.72 Range $271.61 - $305.95

Q2 2022

Shares 28,000 Value ($000) $7,890 Avg Close $267.66 Range $233.01 - $293.17

Q1 2022

Shares 28,000 Value ($000) $7,307 Avg Close $237.33 Range $214.66 - $263.58

Q4 2021

Shares 31,000 Value ($000) $6,896 Avg Close $194.45 Range $176.36 - $224.49

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	9,355	$4,241	$431.03	$392.50 - $464.44
Q3 2025	8,300	$3,251	$417.92	$362.50 - $484.56
Q2 2025	8,300	$3,753	$460.83	$416.60 - $510.77
Q1 2025	8,300	$4,024	$466.00	$397.25 - $519.68
Q4 2023	15,116	$6,211	$369.42	$341.85 - $413.00
Q3 2023	21,395	$7,440	$349.73	$335.82 - $367.00
Q2 2023	30,910	$10,762	$336.94	$313.47 - $354.94
Q1 2023	32,470	$10,230	$299.93	$282.21 - $325.19
Q4 2022	35,307	$10,207	$304.77	$283.58 - $324.75
Q3 2022	28,500	$8,345	$287.72	$271.61 - $305.95
Q2 2022	28,000	$7,890	$267.66	$233.01 - $293.17
Q1 2022	28,000	$7,307	$237.33	$214.66 - $263.58
Q4 2021	31,000	$6,896	$194.45	$176.36 - $224.49