Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
OPEN	OPENDOOR TECHNOLOGIES INC	3,940,904	$18.21M	3.3%	$4.62	—	COM	683712103
CBRS	CEREBRAS SYSTEMS INC	60,500	$13.37M	2.5%	$221.00	—	COM CL A A	15675D103
SPCX	SPACE EXPLORATION TECHN CORP	40,000	$6.834M	1.3%	$170.86	—	CLASS A COM STK A	84615Q103
MICC	MAGNUM ICE CREAM CO NV	98,221	$1.496M	0.3%	$15.24	—	ORD SHS	N5505D105
ZTS	ZOETIS INC	17,322	$1.245M	0.2%	$71.86	—	CL A	98978V103
LEGN	LEGEND BIOTECH CORP	35,400	$1.022M	0.2%	$28.88	—	SPONSORED ADS	52490G102
TTE	TOTALENERGIES SE	10,723	$729K	0.1%	$68.03	—	ACT	F92124100
NU	NU HLDGS LTD	44,000	$588K	0.1%	$13.36	—	ORD SHS CL A	G6683N103
LULU	LULULEMON ATHLETICA INC	5,063	$578K	0.1%	$114.18	—	COM	550021109
SA	SEABRIDGE GOLD INC	16,512	$425K	0.1%	$25.74	—	COM A	811927102
ENGN	ENGENE THERAPEUTICS INC	170,000	$294K	0.1%	$1.73	—	COM A	29286X101
CSAN	COSAN S A	52,000	$150K	0.0%	$2.88	—	ADS	22113B103

Increased Positions (16)

TSLA TESLA INC 17.6%

Value $95.9M (+16.2%) Shares 228,000 (+2.7%) Est. Cost $214.34 Unrealized —

AMZN AMAZON COM INC 6.1%

Value $33.37M (+28.2%) Shares 140,000 (+12.0%) Est. Cost $133.97 Unrealized —

IREN IREN LIMITED 2.9%

Value $15.56M (+41.7%) Shares 340,150 (+6.2%) Est. Cost $40.42 Unrealized —

IONS IONIS PHARMACEUTICALS INC 4.7%

Value $25.37M (+16.5%) Shares 319,924 (+10.3%) Est. Cost $46.46 Unrealized —

ARQT ARCUTIS BIOTHERAPEUTICS INC 1.9%

Value $10.47M (+38.5%) Shares 399,367 (+24.4%) Est. Cost $14.68 Unrealized —

BIIB BIOGEN INC 1.9%

Value $10.46M (+30.2%) Shares 48,400 (+10.5%) Est. Cost $147.68 Unrealized —

HIMS HIMS & HERS HEALTH INC 0.5%

Value $2.774M (+234.0%) Shares 80,000 (+100.0%) Est. Cost $41.29 Unrealized —

LMND LEMONADE INC 3.2%

Value $17.58M (+9.9%) Shares 270,259 (+5.9%) Est. Cost $57.40 Unrealized —

SRPT SAREPTA THERAPEUTICS INC 0.5%

Value $2.453M (+145.1%) Shares 136,500 (+196.7%) Est. Cost $19.00 Unrealized —

BEAM BEAM THERAPEUTICS INC 0.4%

Value $2.412M (+58.2%) Shares 70,282 (+9.8%) Est. Cost $21.94 Unrealized —

TSHA TAYSHA GENE THERAPIES INC 0.2%

Value $1.355M (+66.6%) Shares 198,900 (+9.3%) Est. Cost $3.55 Unrealized —

CRSP CRISPR THERAPEUTICS AG 0.5%

Value $2.453M (+20.3%) Shares 44,974 (+4.9%) Est. Cost $49.87 Unrealized —

BNTX BIONTECH SE 0.5%

Value $2.801M (+16.7%) Shares 30,100 (+11.5%) Est. Cost $99.36 Unrealized —

BTG B2GOLD CORP 0.1%

Value $730K (+66.9%) Shares 195,083 (+102.2%) Est. Cost $4.42 Unrealized —

TDW TIDEWATER INC NEW 0.1%

Value $579K (+26.3%) Shares 8,683 (+58.4%) Est. Cost $50.35 Unrealized —

RIG TRANSOCEAN LTD 0.1%

Value $712K (+0.7%) Shares 145,604 (+36.6%) Est. Cost $3.69 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
TSLA	TESLA INC	228,000 (+2.7%)	$95.9M (+16.2%)	17.6%	$214.34	—	COM	88160R101
AMZN	AMAZON COM INC	140,000 (+12.0%)	$33.37M (+28.2%)	6.1%	$133.97	—	COM	023135106
IREN	IREN LIMITED	340,150 (+6.2%)	$15.56M (+41.7%)	2.9%	$40.42	—	ORDINARY SHARES	Q4982L109
IONS	IONIS PHARMACEUTICALS INC	319,924 (+10.3%)	$25.37M (+16.5%)	4.7%	$46.46	—	COM	462222100
ARQT	ARCUTIS BIOTHERAPEUTICS INC	399,367 (+24.4%)	$10.47M (+38.5%)	1.9%	$14.68	—	COM	03969K108
BIIB	BIOGEN INC	48,400 (+10.5%)	$10.46M (+30.2%)	1.9%	$147.68	—	COM	09062X103
HIMS	HIMS & HERS HEALTH INC	80,000 (+100.0%)	$2.774M (+234.0%)	0.5%	$41.29	—	COM CL A	433000106
LMND	LEMONADE INC	270,259 (+5.9%)	$17.58M (+9.9%)	3.2%	$57.40	—	COM	52567D107
SRPT	SAREPTA THERAPEUTICS INC	136,500 (+196.7%)	$2.453M (+145.1%)	0.5%	$19.00	—	COM	803607100
BEAM	BEAM THERAPEUTICS INC	70,282 (+9.8%)	$2.412M (+58.2%)	0.4%	$21.94	—	COM	07373V105
TSHA	TAYSHA GENE THERAPIES INC	198,900 (+9.3%)	$1.355M (+66.6%)	0.2%	$3.55	—	COM SHS	877619106
CRSP	CRISPR THERAPEUTICS AG	44,974 (+4.9%)	$2.453M (+20.3%)	0.5%	$49.87	—	NAMEN AKT	H17182108
BNTX	BIONTECH SE	30,100 (+11.5%)	$2.801M (+16.7%)	0.5%	$99.36	—	SPONSORED ADS	09075V102
BTG	B2GOLD CORP	195,083 (+102.2%)	$730K (+66.9%)	0.1%	$4.42	—	COM	11777Q209
TDW	TIDEWATER INC NEW	8,683 (+58.4%)	$579K (+26.3%)	0.1%	$50.35	—	COM	88642R109
RIG	TRANSOCEAN LTD	145,604 (+36.6%)	$712K (+0.7%)	0.1%	$3.69	—	REGISTERED SHS	H8817H100

Exited Positions (11)

COIN COINBASE GLOBAL INC 2.5%

Value $13.79M Shares 79,000 Est. Cost $245.78 Unrealized —

SE SEA LTD 2.1%

Value $11.43M Shares 138,000 Est. Cost $52.53 Unrealized —

ESPR ESPERION THERAPEUTICS INC NE 1.7%

Value $9.04M Shares 3,299,441 Est. Cost $3.42 Unrealized —

ENGN ENGENE HOLDINGS INC 0.4%

Value $2.398M Shares 352,087 Est. Cost $8.01 Unrealized —

STOK STOKE THERAPEUTICS INC 0.3%

Value $1.628M Shares 50,000 Est. Cost $30.06 Unrealized —

PFE PFIZER INC 0.3%

Value $1.479M Shares 52,679 Est. Cost $25.30 Unrealized —

SLB SLB LIMITED 0.2%

Value $948K Shares 18,451 Est. Cost $35.19 Unrealized —

SA SEABRIDGE GOLD INC 0.1%

Value $704K Shares 24,828 Est. Cost $14.37 Unrealized —

NE NOBLE CORP PLC 0.1%

Value $336K Shares 6,849 Est. Cost $35.00 Unrealized —

PAAS PAN AMERN SILVER CORP 0.0%

Value $213K Shares 3,900 Est. Cost $58.40 Unrealized —

URNM SPROTT FDS TR 0.0%

Value $209K Shares 3,302 Est. Cost $44.10 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
COIN	COINBASE GLOBAL INC	79,000	$13.79M	2.5%	$245.78	—	—	19260Q107
SE	SEA LTD	138,000	$11.43M	2.1%	$52.53	—	—	81141R100
ESPR	ESPERION THERAPEUTICS INC NE	3,299,441	$9.04M	1.7%	$3.42	—	—	29664W105
ENGN	ENGENE HOLDINGS INC	352,087	$2.398M	0.4%	$8.01	—	—	29286M105
STOK	STOKE THERAPEUTICS INC	50,000	$1.628M	0.3%	$30.06	—	—	86150R107
PFE	PFIZER INC	52,679	$1.479M	0.3%	$25.30	—	—	717081103
SLB	SLB LIMITED	18,451	$948K	0.2%	$35.19	—	—	806857108
SA	SEABRIDGE GOLD INC	24,828	$704K	0.1%	$14.37	—	—	811916105
NE	NOBLE CORP PLC	6,849	$336K	0.1%	$35.00	—	—	G65431127
PAAS	PAN AMERN SILVER CORP	3,900	$213K	0.0%	$58.40	—	—	697900108
URNM	SPROTT FDS TR	3,302	$209K	0.0%	$44.10	—	—	85208P303

Decreased Positions (18)

SPOT SPOTIFY TECHNOLOGY S A 4.6%

Value $25.25M (-22.3%) Shares 55,000 (-17.9%) Est. Cost $198.24 Unrealized —

QURE UNIQURE NV 2.8%

Value $15.12M (+90.1%) Shares 328,322 (-32.5%) Est. Cost $16.52 Unrealized —

SHOP SHOPIFY INC 7.8%

Value $42.25M (-12.5%) Shares 370,000 (-9.1%) Est. Cost $50.26 Unrealized —

ARWR ARROWHEAD PHARMACEUTICALS IN 3.5%

Value $19.09M (-17.0%) Shares 234,222 (-36.2%) Est. Cost $35.12 Unrealized —

RARE ULTRAGENYX PHARMACEUTICAL IN 2.1%

Value $11.31M (+48.0%) Shares 338,800 (-7.1%) Est. Cost $47.16 Unrealized —

URGN UROGEN PHARMA LTD 1.4%

Value $7.728M (+80.5%) Shares 210,000 (-11.8%) Est. Cost $15.38 Unrealized —

DNLI DENALI THERAPEUTICS INC 1.1%

Value $5.912M (+20.8%) Shares 229,857 (-9.8%) Est. Cost $19.63 Unrealized —

BMRN BIOMARIN PHARMACEUTICAL INC 0.8%

Value $4.292M (-17.7%) Shares 75,000 (-18.7%) Est. Cost $58.72 Unrealized —

MGTX MEIRAGTX HLDGS PLC 0.5%

Value $2.649M (+44.2%) Shares 196,112 (-7.5%) Est. Cost $6.33 Unrealized —

ALNY ALNYLAM PHARMACEUTICALS INC 0.6%

Value $3.423M (-15.3%) Shares 11,372 (-7.0%) Est. Cost $353.27 Unrealized —

RNAC CARTESIAN THERAPEUTICS INC 0.3%

Value $1.58M (+43.5%) Shares 151,675 (-15.3%) Est. Cost $8.05 Unrealized —

LXEO LEXEO THERAPEUTICS INC 0.1%

Value $722K (-38.6%) Shares 155,000 (-24.4%) Est. Cost $6.87 Unrealized —

MOH MOLINA HEALTHCARE INC 0.1%

Value $681K (-37.2%) Shares 2,979 (-63.4%) Est. Cost $168.64 Unrealized —

VRTX VERTEX PHARMACEUTICALS INC 0.9%

Value $4.669M (-7.9%) Shares 9,400 (-17.2%) Est. Cost $463.02 Unrealized —

FDMT 4D MOLECULAR THERAPEUTICS IN 0.2%

Value $1.198M (-24.4%) Shares 90,110 (-47.1%) Est. Cost $10.95 Unrealized —

ABEV AMBEV SA 0.5%

Value $2.519M (-9.1%) Shares 802,167 (-15.4%) Est. Cost $2.48 Unrealized —

ZLAB ZAI LAB LTD 0.4%

Value $2.322M (-6.6%) Shares 122,189 (-7.6%) Est. Cost $63.19 Unrealized —

AXSM AXSOME THERAPEUTICS INC. 1.8%

Value $9.777M (-1.5%) Shares 39,944 (-32.0%) Est. Cost $77.80 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
SPOT	SPOTIFY TECHNOLOGY S A	55,000 (-17.9%)	$25.25M (-22.3%)	4.6%	$198.24	—	SHS	L8681T102
QURE	UNIQURE NV	328,322 (-32.5%)	$15.12M (+90.1%)	2.8%	$16.52	—	SHS	N90064101
SHOP	SHOPIFY INC	370,000 (-9.1%)	$42.25M (-12.5%)	7.8%	$50.26	—	CL A SUB VTG SHS	82509L107
ARWR	ARROWHEAD PHARMACEUTICALS IN	234,222 (-36.2%)	$19.09M (-17.0%)	3.5%	$35.12	—	COM	04280A100
RARE	ULTRAGENYX PHARMACEUTICAL IN	338,800 (-7.1%)	$11.31M (+48.0%)	2.1%	$47.16	—	COM	90400D108
URGN	UROGEN PHARMA LTD	210,000 (-11.8%)	$7.728M (+80.5%)	1.4%	$15.38	—	COM	M96088105
DNLI	DENALI THERAPEUTICS INC	229,857 (-9.8%)	$5.912M (+20.8%)	1.1%	$19.63	—	COM	24823R105
BMRN	BIOMARIN PHARMACEUTICAL INC	75,000 (-18.7%)	$4.292M (-17.7%)	0.8%	$58.72	—	COM	09061G101
MGTX	MEIRAGTX HLDGS PLC	196,112 (-7.5%)	$2.649M (+44.2%)	0.5%	$6.33	—	COM	G59665102
ALNY	ALNYLAM PHARMACEUTICALS INC	11,372 (-7.0%)	$3.423M (-15.3%)	0.6%	$353.27	—	COM	02043Q107
RNAC	CARTESIAN THERAPEUTICS INC	151,675 (-15.3%)	$1.58M (+43.5%)	0.3%	$8.05	—	COM NEW	816212302
LXEO	LEXEO THERAPEUTICS INC	155,000 (-24.4%)	$722K (-38.6%)	0.1%	$6.87	—	COM	52886X107
MOH	MOLINA HEALTHCARE INC	2,979 (-63.4%)	$681K (-37.2%)	0.1%	$168.64	—	COM	60855R100
VRTX	VERTEX PHARMACEUTICALS INC	9,400 (-17.2%)	$4.669M (-7.9%)	0.9%	$463.02	—	COM	92532F100
FDMT	4D MOLECULAR THERAPEUTICS IN	90,110 (-47.1%)	$1.198M (-24.4%)	0.2%	$10.95	—	COM	35104E100
ABEV	AMBEV SA	802,167 (-15.4%)	$2.519M (-9.1%)	0.5%	$2.48	—	SPONSORED ADR	02319V103
ZLAB	ZAI LAB LTD	122,189 (-7.6%)	$2.322M (-6.6%)	0.4%	$63.19	—	ADR	98887Q104
AXSM	AXSOME THERAPEUTICS INC.	39,944 (-32.0%)	$9.777M (-1.5%)	1.8%	$77.80	—	COM	05464T104

Unchanged Positions (15)

AMD ADVANCED MICRO DEVICES INC 6.6%

Value $36.02M Shares 62,000 Est. Cost $163.32 Unrealized —

PLTR PALANTIR TECHNOLOGIES INC 4.3%

Value $23.33M Shares 200,000 Est. Cost $15.54 Unrealized —

NVDA NVIDIA CORPORATION 3.0%

Value $16.21M Shares 81,000 Est. Cost $100.98 Unrealized —

PRQR PROQR THRAPEUTICS N V 1.9%

Value $10.27M Shares 5,520,024 Est. Cost $6.48 Unrealized —

KRYS KRYSTAL BIOTECH INC 0.8%

Value $4.152M Shares 11,170 Est. Cost $135.26 Unrealized —

ASTS AST SPACEMOBILE INC 2.4%

Value $12.88M Shares 145,000 Est. Cost $53.79 Unrealized —

FATE FATE THERAPEUTICS INC 0.2%

Value $1.119M Shares 414,311 Est. Cost $1.58 Unrealized —

MRNA MODERNA INC 0.4%

Value $2.1M Shares 29,994 Est. Cost $64.57 Unrealized —

WVE WAVE LIFE SCIENCES LTD 0.3%

Value $1.4M Shares 241,010 Est. Cost $10.01 Unrealized —

VRDN VIRIDIAN THERAPEUTICS INC 0.6%

Value $3.187M Shares 173,516 Est. Cost $27.43 Unrealized —

SD SANDRIDGE ENERGY INC 0.1%

Value $531K Shares 38,792 Est. Cost $12.11 Unrealized —

AUTL AUTOLUS THERAPEUTICS LTD 0.1%

Value $581K Shares 363,430 Est. Cost $2.80 Unrealized —

VYGR VOYAGER THERAPEUTICS INC 0.1%

Value $420K Shares 120,000 Est. Cost $3.91 Unrealized —

RCKT ROCKET PHARMACEUTICALS INC 0.2%

Value $835K Shares 244,146 Est. Cost $13.36 Unrealized —

NOV NOV INC 0.1%

Value $780K Shares 42,026 Est. Cost $15.12 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
AMD	ADVANCED MICRO DEVICES INC	62,000	$36.02M	6.6%	$163.32	—	COM	007903107
PLTR	PALANTIR TECHNOLOGIES INC	200,000	$23.33M	4.3%	$15.54	—	CL A	69608A108
NVDA	NVIDIA CORPORATION	81,000	$16.21M	3.0%	$100.98	—	COM	67066G104
PRQR	PROQR THRAPEUTICS N V	5,520,024	$10.27M	1.9%	$6.48	—	SHS EURO	N71542109
KRYS	KRYSTAL BIOTECH INC	11,170	$4.152M	0.8%	$135.26	—	COM	501147102
ASTS	AST SPACEMOBILE INC	145,000	$12.88M	2.4%	$53.79	—	COM CL A	00217D100
FATE	FATE THERAPEUTICS INC	414,311	$1.119M	0.2%	$1.58	—	COM	31189P102
MRNA	MODERNA INC	29,994	$2.1M	0.4%	$64.57	—	COM	60770K107
WVE	WAVE LIFE SCIENCES LTD	241,010	$1.4M	0.3%	$10.01	—	SHS	Y95308105
VRDN	VIRIDIAN THERAPEUTICS INC	173,516	$3.187M	0.6%	$27.43	—	COM	92790C104
SD	SANDRIDGE ENERGY INC	38,792	$531K	0.1%	$12.11	—	COM NEW	80007P869
AUTL	AUTOLUS THERAPEUTICS LTD	363,430	$581K	0.1%	$2.80	—	SPON ADS	05280R100
VYGR	VOYAGER THERAPEUTICS INC	120,000	$420K	0.1%	$3.91	—	COM	92915B106
RCKT	ROCKET PHARMACEUTICALS INC	244,146	$835K	0.2%	$13.36	—	COM	77313F106
NOV	NOV INC	42,026	$780K	0.1%	$15.12	—	COM	62955J103