XENON PHARMACEUTICALS INC

Ticker: XENE CUSIP: 98420N105 Class: Common Stock

Redmile Group, LLC's Holding History (CIK: 0001425738)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 133,882 Value ($000) $6,001 Avg Close $42.00 Range $37.23 - $46.60

Q3 2023

Shares 419,568 Value ($000) $14,332 Avg Close $37.40 Range $33.93 - $40.13

Q2 2023

Shares 1,120,476 Value ($000) $43,138 Avg Close $39.75 Range $33.60 - $43.75

Q1 2023

Shares 1,325,832 Value ($000) $47,452 Avg Close $36.94 Range $32.64 - $41.25

Q4 2022

Shares 2,360,414 Value ($000) $93,071 Avg Close $36.42 Range $31.79 - $40.06

Q3 2022

Shares 2,370,614 Value ($000) $85,579 Avg Close $35.95 Range $28.98 - $41.39

Q2 2022

Shares 1,639,344 Value ($000) $49,869 Avg Close $30.24 Range $24.94 - $35.69

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	133,882	$6,001	$42.00	$37.23 - $46.60
Q3 2023	419,568	$14,332	$37.40	$33.93 - $40.13
Q2 2023	1,120,476	$43,138	$39.75	$33.60 - $43.75
Q1 2023	1,325,832	$47,452	$36.94	$32.64 - $41.25
Q4 2022	2,360,414	$93,071	$36.42	$31.79 - $40.06
Q3 2022	2,370,614	$85,579	$35.95	$28.98 - $41.39
Q2 2022	1,639,344	$49,869	$30.24	$24.94 - $35.69