ZYMEWORKS INC

Ticker: ZYME CUSIP: 98985Y108 Class: Common Stock

COMERICA BANK's Holding History (CIK: 0000901541)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 211 Value ($000) $6 Avg Close $21.81 Range $16.00 - $28.49

Q3 2025

Shares 211 Value ($000) $4 Avg Close $14.31 Range $11.51 - $17.60

Q3 2023

Shares 77 Value ($000) $0 Avg Close $7.39 Range $6.11 - $8.80

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	211	$6	$21.81	$16.00 - $28.49
Q3 2025	211	$4	$14.31	$11.51 - $17.60
Q3 2023	77	$0	$7.39	$6.11 - $8.80