CASI PHARMACEUTICALS INC

Ticker: CASIF CUSIP: G1933S101 Class: Stock

Holders for Q4 2025 Position Changes for Q4 2025

Note: Option positions (PUT/CALL) are excluded.

New Positions (1)

CITADEL ADVISORS LLC

Value ($000) $12 Shares 14,045

Institution	Shares	Value ($000)
CITADEL ADVISORS LLC	14,045	$12

Increased Positions (1)

Value ($000) $1 (+2334.8%) Shares 659 (+4607.1%)

Institution	Prev Shares	Curr Shares	Change
UBS Group AG	14	659	+645 (+4607.1%)

Decreased Positions (5)

BANK OF AMERICA CORP /DE/

Value ($000) $17 (-96.0%) Shares 19,935 (-92.2%)

Woodline Partners LP

Value ($000) $113 (-58.8%) Shares 133,406 (-19.5%)

TWO SIGMA INVESTMENTS, LP

Value ($000) $20 (-63.4%) Shares 23,787 (-28.5%)

RENAISSANCE TECHNOLOGIES LLC

Value ($000) $37 (-49.7%) Shares 43,100 (-1.8%)

SIMPLEX TRADING, LLC

Value ($000) $0 Shares 133 (-8.3%)

Institution	Prev Shares	Curr Shares	Change
BANK OF AMERICA CORP /DE/	254,884	19,935	-234,949 (-92.2%)
Woodline Partners LP	165,640	133,406	-32,234 (-19.5%)
TWO SIGMA INVESTMENTS, LP	33,267	23,787	-9,480 (-28.5%)
RENAISSANCE TECHNOLOGIES LLC	43,900	43,100	-800 (-1.8%)
SIMPLEX TRADING, LLC	145	133	-12 (-8.3%)

Exited Positions (7)

Foresite Capital Management VI LLC

Value ($000) $1,627 Shares 979,956

Ground Swell Capital, LLC

Value ($000) $17 Shares 10,135

Wellington Shields Capital Management, LLC

Value ($000) $115 Shares 69,535

Wellington Shields & Co., LLC

Value ($000) $50 Shares 30,091

GROUP ONE TRADING, L.P.

Value ($000) $4 Shares 2,300

BlackRock, Inc.

Value ($000) $0 Shares 296

NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO

Value ($000) $0 Shares 13

Institution	Prev Shares	Prev Value ($000)
Foresite Capital Management VI LLC	979,956	$1,627
Ground Swell Capital, LLC	10,135	$17
Wellington Shields Capital Management, LLC	69,535	$115
Wellington Shields & Co., LLC	30,091	$50
GROUP ONE TRADING, L.P.	2,300	$4
BlackRock, Inc.	296	$0
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO	13	$0