ESTABLISHMENT LABS HLDGS INC

Ticker: ESTA CUSIP: G31249108 Class: Common Stock

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019

Shares 50,000 Value ($000) $1,202 Avg Close $26.54 Range $23.03 - $30.06

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2019	50,000	$1,202	$26.54	$23.03 - $30.06