ITERUM THERAPEUTICS PLC

Ticker: ITRM CUSIP: G6333L200 Class: SHS NEW

Holders for Q4 2025 Position Changes for Q4 2025

Note: Option positions (PUT/CALL) are excluded.

New Positions (1)

Ground Swell Capital, LLC

Value ($000) $7 Shares 20,477

Institution	Shares	Value ($000)
Ground Swell Capital, LLC	20,477	$7

Increased Positions (3)

Apollon Financial, LLC

Value ($000) $211 (+25.9%) Shares 630,250 (+151.8%)

JANE STREET GROUP, LLC

Value ($000) $97 (+896.7%) Shares 289,410 (+1893.5%)

Value ($000) $40 (+595.2%) Shares 119,948 (+1290.5%)

Institution	Prev Shares	Curr Shares	Change
Apollon Financial, LLC	250,250	630,250	+380,000 (+151.8%)
JANE STREET GROUP, LLC	14,518	289,410	+274,892 (+1893.5%)
UBS Group AG	8,626	119,948	+111,322 (+1290.5%)

Decreased Positions (3)

Value ($000) $2 (-66.8%) Shares 5,713 (-33.7%)

Virtu Financial LLC

Value ($000) $0 (-78.1%) Shares 22,062 (-53.2%)

SG Americas Securities, LLC

Value ($000) $0 (-63.6%) Shares 12,782 (-24.0%)

Institution	Prev Shares	Curr Shares	Change
MORGAN STANLEY	8,613	5,713	-2,900 (-33.7%)
Virtu Financial LLC	47,131	22,062	-25,069 (-53.2%)
SG Americas Securities, LLC	16,820	12,782	-4,038 (-24.0%)

Exited Positions (7)

Squarepoint Ops LLC

Value ($000) $297 Shares 443,972

OneDigital Investment Advisors LLC

Value ($000) $128 Shares 191,000

RENAISSANCE TECHNOLOGIES LLC

Value ($000) $55 Shares 81,694

Alpine Global Management, LLC

Value ($000) $7 Shares 10,000

SUSQUEHANNA INTERNATIONAL GROUP, LLP

Value ($000) $8 Shares 11,701

GGM Financials LLC

Value ($000) $0 Shares 1

Value ($000) $0 Shares 66

Institution	Prev Shares	Prev Value ($000)
Squarepoint Ops LLC	443,972	$297
OneDigital Investment Advisors LLC	191,000	$128
RENAISSANCE TECHNOLOGIES LLC	81,694	$55
Alpine Global Management, LLC	10,000	$7
SUSQUEHANNA INTERNATIONAL GROUP, LLP	11,701	$8
GGM Financials LLC	1	$0
CWM, LLC	66	$0