CRISPR THERAPEUTICS AG

Ticker: CRSP CUSIP: H17182108 Class: NAMEN AKT

STATE OF MICHIGAN RETIREMENT SYSTEM's Holding History (CIK: 0000762152)

Note: Option positions (PUT/CALL) are excluded.

Q3 2021

Shares 32,386 Value ($000) $3,625 Avg Close $125.59 Range $109.63 - $163.00

Q2 2021

Shares 32,386 Value ($000) $5,243 Avg Close $121.62 Range $95.11 - $169.76

Q1 2021

Shares 32,386 Value ($000) $3,946 Avg Close $151.00 Range $100.00 - $220.20

Q4 2020

Shares 32,386 Value ($000) $4,959 Avg Close $118.20 Range $79.31 - $181.42

Q3 2020

Shares 43,396 Value ($000) $3,630 Avg Close $88.70 Range $74.00 - $105.12

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2021	32,386	$3,625	$125.59	$109.63 - $163.00
Q2 2021	32,386	$5,243	$121.62	$95.11 - $169.76
Q1 2021	32,386	$3,946	$151.00	$100.00 - $220.20
Q4 2020	32,386	$4,959	$118.20	$79.31 - $181.42
Q3 2020	43,396	$3,630	$88.70	$74.00 - $105.12