WAVE LIFE SCIENCES LTD

Ticker: WVE CUSIP: Y95308105 Class: Common Stock

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 408,166 Value ($000) $6,939 Avg Close $10.16 Range $6.51 - $21.73

Q3 2025

Shares 50,000 Value ($000) $366 Avg Close $8.09 Range $6.25 - $10.58

Q4 2020

Shares 414,959 Value ($000) $3,266 Avg Close $8.39 Range $6.76 - $9.73

Q3 2020

Shares 931,200 Value ($000) $7,906 Avg Close $10.96 Range $8.17 - $19.98

Q2 2020

Shares 293,000 Value ($000) $3,050 Avg Close $9.41 Range $7.40 - $11.79

Q2 2019

Shares 307,967 Value ($000) $8,035 Avg Close $28.04 Range $22.25 - $43.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	408,166	$6,939	$10.16	$6.51 - $21.73
Q3 2025	50,000	$366	$8.09	$6.25 - $10.58
Q4 2020	414,959	$3,266	$8.39	$6.76 - $9.73
Q3 2020	931,200	$7,906	$10.96	$8.17 - $19.98
Q2 2020	293,000	$3,050	$9.41	$7.40 - $11.79
Q2 2019	307,967	$8,035	$28.04	$22.25 - $43.00