WAVE LIFE SCIENCES LTD

Ticker: WVE CUSIP: Y95308105 Class: Common Stock

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q2 2017

Shares 125,000 Value ($000) $2,325 Avg Close $21.55 Range $18.50 - $27.85

Q1 2017

Shares 78,300 Value ($000) $2,153 Avg Close $27.93 Range $24.98 - $31.25

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2017	125,000	$2,325	$21.55	$18.50 - $27.85
Q1 2017	78,300	$2,153	$27.93	$24.98 - $31.25