WAVE LIFE SCIENCES LTD

Ticker: WVE CUSIP: Y95308105 Class: Common Stock

Siren, L.L.C.'s Holding History (CIK: 0002005245)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 2,450,000 Value ($000) $41,650 Avg Close $10.16 Range $6.51 - $21.73

Q3 2025

Shares 3,696,322 Value ($000) $27,057 Avg Close $8.09 Range $6.25 - $10.58

Q2 2025

Shares 3,696,322 Value ($000) $24,026 Avg Close $6.60 Range $5.28 - $8.39

Q1 2025

Shares 3,696,322 Value ($000) $29,866 Avg Close $10.94 Range $7.92 - $13.92

Q4 2024

Shares 3,750,491 Value ($000) $46,394 Avg Close $13.35 Range $7.85 - $16.74

Q3 2024

Shares 5,721,172 Value ($000) $46,914 Avg Close $5.98 Range $4.87 - $9.92

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	2,450,000	$41,650	$10.16	$6.51 - $21.73
Q3 2025	3,696,322	$27,057	$8.09	$6.25 - $10.58
Q2 2025	3,696,322	$24,026	$6.60	$5.28 - $8.39
Q1 2025	3,696,322	$29,866	$10.94	$7.92 - $13.92
Q4 2024	3,750,491	$46,394	$13.35	$7.85 - $16.74
Q3 2024	5,721,172	$46,914	$5.98	$4.87 - $9.92