Casdin Capital, LLC Diversified Active

CIK: 0001534261 · Show all filings

Period: Q1 2023 (← Previous) (Next →)

Filing Date: May 15, 2023

Total Value ($000): $1,213,999 (100.0% shares, 0.0% debt)

Holdings (41)

BLFS BIOLIFE SOLUTIONS INC 13.6%

Value ($000) $164,681 Shares 7,571,535 Est. Cost $20.20 Unrealized +11.3%

SRPT SAREPTA THERAPEUTICS INC 13.2%

Value ($000) $159,883 Shares 1,160,000 Est. Cost $99.50 Unrealized +30.4%

RLAY RELAY THERAPEUTICS INC 7.7%

Value ($000) $93,856 Shares 5,698,574 Est. Cost $26.85 Unrealized -33.2%

— EQRX INC 6.3%

Value ($000) $76,684 Shares 39,527,669 Est. Cost $6.82 Unrealized —

ILMN ILLUMINA INC 5.3%

Value ($000) $63,951 Shares 275,000 Est. Cost $197.84 Unrealized +3.4%

ALNY ALNYLAM PHARMACEUTICALS INC 4.5%

Value ($000) $54,086 Shares 270,000 Est. Cost $110.93 Unrealized +89.5%

NTLA INTELLIA THERAPEUTICS INC 3.9%

Value ($000) $47,519 Shares 1,275,000 Est. Cost $44.50 Unrealized -11.9%

PLRX PLIANT THERAPEUTICS INC 3.7%

Value ($000) $44,555 Shares 1,675,000 Est. Cost $20.11 Unrealized +41.6%

RVMD REVOLUTION MEDICINES INC 3.2%

Value ($000) $39,205 Shares 1,810,000 Est. Cost $29.92 Unrealized -17.7%

EXAS EXACT SCIENCES CORP 3.2%

Value ($000) $38,313 Shares 565,000 Est. Cost $81.07 Unrealized -20.7%

— GENEDX HOLDINGS CORP 3.1%

Value ($000) $37,285 Shares 102,151,785 Est. Cost $0.82 Unrealized —

— SOMALOGIC INC 2.6%

Value ($000) $32,141 Shares 12,604,275 Est. Cost $12.23 Unrealized —

— VERVE THERAPEUTICS INC 2.5%

Value ($000) $30,579 Shares 2,120,571 Est. Cost $59.19 Unrealized —

— BLUEPRINT MEDICINES CORP 2.5%

Value ($000) $30,143 Shares 670,000 Est. Cost $3820.05 Unrealized —

DNLI DENALI THERAPEUTICS INC 2.5%

Value ($000) $29,952 Shares 1,300,000 Est. Cost $29.48 Unrealized -6.7%

MXCT MAXCYTE INC 2.0%

Value ($000) $24,379 Shares 4,925,000 Est. Cost $15.08 Unrealized -67.3%

— 2SEVENTY BIO INC 1.7%

Value ($000) $20,644 Shares 2,023,913 Est. Cost $11.78 Unrealized —

ABCL ABCELLERA BIOLOGICS INC 1.6%

Value ($000) $19,001 Shares 2,520,000 Est. Cost $10.18 Unrealized -10.8%

— MIRATI THERAPEUTICS INC 1.6%

Value ($000) $18,962 Shares 510,000 Est. Cost $59.13 Unrealized —

FDMT 4D MOLECULAR THERAPEUTICS IN 1.5%

Value ($000) $18,393 Shares 1,070,000 Est. Cost $17.09 Unrealized +13.8%

BEAM BEAM THERAPEUTICS INC 1.4%

Value ($000) $17,453 Shares 570,000 Est. Cost $58.84 Unrealized -32.9%

TNYA TENAYA THERAPEUTICS INC 1.4%

Value ($000) $17,325 Shares 6,078,860 Est. Cost $13.68 Unrealized -79.5%

GPCR STRUCTURE THERAPEUTICS INC 1.3%

Value ($000) $16,106 Shares 677,017 Est. Cost $23.79 Unrealized —

— PROMETHEUS BIOSCIENCES INC 1.3%

Value ($000) $16,098 Shares 150,000 Est. Cost $110.00 Unrealized —

RNAM AVIDITY BIOSCIENCES INC 1.1%

Value ($000) $13,048 Shares 850,000 Est. Cost $14.91 Unrealized +47.6%

FATE FATE THERAPEUTICS INC 1.0%

Value ($000) $11,685 Shares 2,050,000 Est. Cost $17.49 Unrealized -65.5%

IPSC CENTURY THERAPEUTICS INC 0.9%

Value ($000) $11,126 Shares 3,206,380 Est. Cost $25.37 Unrealized -82.7%

TWST TWIST BIOSCIENCE CORP 0.9%

Value ($000) $10,556 Shares 700,000 Est. Cost $30.77 Unrealized -28.2%

ABSI ABSCI CORPORATION 0.8%

Value ($000) $9,438 Shares 5,393,260 Est. Cost $19.41 Unrealized -87.5%

PRME PRIME MEDICINE INC 0.7%

Value ($000) $9,033 Shares 734,350 Est. Cost $18.06 Unrealized -9.8%

— DICE THERAPEUTICS INC 0.7%

Value ($000) $8,882 Shares 310,000 Est. Cost $30.01 Unrealized —

OPRX OPTIMIZERX CORP 0.6%

Value ($000) $7,315 Shares 500,000 Est. Cost $17.02 Unrealized -1.7%

INCY INCYTE CORP 0.5%

Value ($000) $5,601 Shares 77,500 Est. Cost $76.52 Unrealized +2.2%

GLUE MONTE ROSA THERAPEUTICS INC 0.3%

Value ($000) $3,980 Shares 510,882 Est. Cost $20.37 Unrealized -65.9%

TNGX TANGO THERAPEUTICS INC 0.3%

Value ($000) $3,950 Shares 1,000,000 Est. Cost $5.80 Unrealized 0.0%

SRPT SAREPTA THERAPEUTICS INC 0.3%

Value ($000) $3,446 Shares 25,000 Est. Cost $99.50 Unrealized +30.4%

— SINGULAR GENOMICS SYSTEMS IN 0.1%

Value ($000) $1,628 Shares 1,345,722 Est. Cost $18.57 Unrealized —

— INVITAE CORP 0.1%

Value ($000) $1,402 Shares 1,038,388 Est. Cost $330.76 Unrealized —

— EXSCIENTIA PLC 0.1%

Value ($000) $1,134 Shares 213,900 Est. Cost $19.76 Unrealized —

LIANY LIANBIO 0.0%

Value ($000) $403 Shares 206,415 Est. Cost $6.16 Unrealized —

— KRONOS BIO INC 0.0%

Value ($000) $181 Shares 123,839 Est. Cost $29.87 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
BLFS	BIOLIFE SOLUTIONS INC	7,571,535	$164,681	13.6%	$20.20	+11.3%	COM NEW	09062W204
SRPT	SAREPTA THERAPEUTICS INC	1,160,000	$159,883	13.2%	$99.50	+30.4%	COM	803607100
RLAY	RELAY THERAPEUTICS INC	5,698,574	$93,856	7.7%	$26.85	-33.2%	COM	75943R102
—	EQRX INC	39,527,669	$76,684	6.3%	$6.82	—	COM	26886C107
ILMN	ILLUMINA INC	275,000	$63,951	5.3%	$197.84	+3.4%	COM	452327109
ALNY	ALNYLAM PHARMACEUTICALS INC	270,000	$54,086	4.5%	$110.93	+89.5%	COM	02043Q107
NTLA	INTELLIA THERAPEUTICS INC	1,275,000	$47,519	3.9%	$44.50	-11.9%	COM	45826J105
PLRX	PLIANT THERAPEUTICS INC	1,675,000	$44,555	3.7%	$20.11	+41.6%	COM	729139105
RVMD	REVOLUTION MEDICINES INC	1,810,000	$39,205	3.2%	$29.92	-17.7%	COM	76155X100
EXAS	EXACT SCIENCES CORP	565,000	$38,313	3.2%	$81.07	-20.7%	COM	30063P105
—	GENEDX HOLDINGS CORP	102,151,785	$37,285	3.1%	$0.82	—	COM CL A	81663L101
—	SOMALOGIC INC	12,604,275	$32,141	2.6%	$12.23	—	CLASS A COM	83444K105
—	VERVE THERAPEUTICS INC	2,120,571	$30,579	2.5%	$59.19	—	COM	92539P101
—	BLUEPRINT MEDICINES CORP	670,000	$30,143	2.5%	$3820.05	—	COM	09627Y109
DNLI	DENALI THERAPEUTICS INC	1,300,000	$29,952	2.5%	$29.48	-6.7%	COM	24823R105
MXCT	MAXCYTE INC	4,925,000	$24,379	2.0%	$15.08	-67.3%	COM	57777K106
—	2SEVENTY BIO INC	2,023,913	$20,644	1.7%	$11.78	—	COMMON STOCK	901384107
ABCL	ABCELLERA BIOLOGICS INC	2,520,000	$19,001	1.6%	$10.18	-10.8%	COM	00288U106
—	MIRATI THERAPEUTICS INC	510,000	$18,962	1.6%	$59.13	—	COM	60468T105
FDMT	4D MOLECULAR THERAPEUTICS IN	1,070,000	$18,393	1.5%	$17.09	+13.8%	COM	35104E100
BEAM	BEAM THERAPEUTICS INC	570,000	$17,453	1.4%	$58.84	-32.9%	COM	07373V105
TNYA	TENAYA THERAPEUTICS INC	6,078,860	$17,325	1.4%	$13.68	-79.5%	COM	87990A106
GPCR	STRUCTURE THERAPEUTICS INC	677,017	$16,106	1.3%	$23.79	—	SPONSORED ADS	86366E106
—	PROMETHEUS BIOSCIENCES INC	150,000	$16,098	1.3%	$110.00	—	COM	74349U108
RNAM	AVIDITY BIOSCIENCES INC	850,000	$13,048	1.1%	$14.91	+47.6%	COM	05370A108
FATE	FATE THERAPEUTICS INC	2,050,000	$11,685	1.0%	$17.49	-65.5%	COM	31189P102
IPSC	CENTURY THERAPEUTICS INC	3,206,380	$11,126	0.9%	$25.37	-82.7%	COM	15673T100
TWST	TWIST BIOSCIENCE CORP	700,000	$10,556	0.9%	$30.77	-28.2%	COM	90184D100
ABSI	ABSCI CORPORATION	5,393,260	$9,438	0.8%	$19.41	-87.5%	COM	00091E109
PRME	PRIME MEDICINE INC	734,350	$9,033	0.7%	$18.06	-9.8%	COM	74168J101
—	DICE THERAPEUTICS INC	310,000	$8,882	0.7%	$30.01	—	COM	23345J104
OPRX	OPTIMIZERX CORP	500,000	$7,315	0.6%	$17.02	-1.7%	COM NEW	68401U204
INCY	INCYTE CORP	77,500	$5,601	0.5%	$76.52	+2.2%	COM	45337C102
GLUE	MONTE ROSA THERAPEUTICS INC	510,882	$3,980	0.3%	$20.37	-65.9%	COM	61225M102
TNGX	TANGO THERAPEUTICS INC	1,000,000	$3,950	0.3%	$5.80	0.0%	COM	87583X109
SRPT	SAREPTA THERAPEUTICS INC	25,000	$3,446	0.3%	$99.50	+30.4%	Call	803607100
—	SINGULAR GENOMICS SYSTEMS IN	1,345,722	$1,628	0.1%	$18.57	—	COM	82933R100
—	INVITAE CORP	1,038,388	$1,402	0.1%	$330.76	—	COM	46185L103
—	EXSCIENTIA PLC	213,900	$1,134	0.1%	$19.76	—	ADS	30223G102
LIANY	LIANBIO	206,415	$403	0.0%	$6.16	—	SPONSORED ADS	53000N108
—	KRONOS BIO INC	123,839	$181	0.0%	$29.87	—	COM	50107A104