Casdin Capital, LLC Diversified Active

Location: New York, NY

CIK: 0001534261 · Show all filings

Period: Q1 2023 (← Previous) (Next →)

Filing Date: May 15, 2023

Total Value: $1.214B (100.0% shares, 0.0% debt)

Holdings (41)

BLFS BIOLIFE SOLUTIONS INC 13.6%

Value $165M Shares 7,571,535 Est. Cost $20.20 Unrealized +11.3%

SRPT SAREPTA THERAPEUTICS INC 13.2%

Value $160M Shares 1,160,000 Est. Cost $99.50 Unrealized +30.4%

RLAY RELAY THERAPEUTICS INC 7.7%

Value $93.86M Shares 5,698,574 Est. Cost $26.85 Unrealized -33.2%

— EQRX INC 6.3%

Value $76.68M Shares 39,527,669 Est. Cost $6.82 Unrealized —

ILMN ILLUMINA INC 5.3%

Value $63.95M Shares 275,000 Est. Cost $197.84 Unrealized +3.4%

ALNY ALNYLAM PHARMACEUTICALS INC 4.5%

Value $54.09M Shares 270,000 Est. Cost $110.93 Unrealized +89.5%

NTLA INTELLIA THERAPEUTICS INC 3.9%

Value $47.52M Shares 1,275,000 Est. Cost $44.50 Unrealized -11.9%

PLRX PLIANT THERAPEUTICS INC 3.7%

Value $44.55M Shares 1,675,000 Est. Cost $20.11 Unrealized +41.6%

RVMD REVOLUTION MEDICINES INC 3.2%

Value $39.2M Shares 1,810,000 Est. Cost $29.92 Unrealized -17.7%

EXAS EXACT SCIENCES CORP 3.2%

Value $38.31M Shares 565,000 Est. Cost $81.07 Unrealized -20.7%

— GENEDX HOLDINGS CORP 3.1%

Value $37.29M Shares 102,151,785 Est. Cost $0.82 Unrealized —

— SOMALOGIC INC 2.6%

Value $32.14M Shares 12,604,275 Est. Cost $12.23 Unrealized —

— VERVE THERAPEUTICS INC 2.5%

Value $30.58M Shares 2,120,571 Est. Cost $59.19 Unrealized —

— BLUEPRINT MEDICINES CORP 2.5%

Value $30.14M Shares 670,000 Est. Cost $3820.05 Unrealized —

DNLI DENALI THERAPEUTICS INC 2.5%

Value $29.95M Shares 1,300,000 Est. Cost $29.48 Unrealized -6.7%

MXCT MAXCYTE INC 2.0%

Value $24.38M Shares 4,925,000 Est. Cost $15.08 Unrealized -67.3%

— 2SEVENTY BIO INC 1.7%

Value $20.64M Shares 2,023,913 Est. Cost $11.78 Unrealized —

ABCL ABCELLERA BIOLOGICS INC 1.6%

Value $19M Shares 2,520,000 Est. Cost $10.18 Unrealized -10.8%

— MIRATI THERAPEUTICS INC 1.6%

Value $18.96M Shares 510,000 Est. Cost $59.13 Unrealized —

FDMT 4D MOLECULAR THERAPEUTICS IN 1.5%

Value $18.39M Shares 1,070,000 Est. Cost $17.09 Unrealized +13.8%

BEAM BEAM THERAPEUTICS INC 1.4%

Value $17.45M Shares 570,000 Est. Cost $58.84 Unrealized -32.9%

TNYA TENAYA THERAPEUTICS INC 1.4%

Value $17.32M Shares 6,078,860 Est. Cost $13.68 Unrealized -79.5%

GPCR STRUCTURE THERAPEUTICS INC 1.3%

Value $16.11M Shares 677,017 Est. Cost $23.79 Unrealized —

— PROMETHEUS BIOSCIENCES INC 1.3%

Value $16.1M Shares 150,000 Est. Cost $110.00 Unrealized —

RNAM AVIDITY BIOSCIENCES INC 1.1%

Value $13.05M Shares 850,000 Est. Cost $14.91 Unrealized +47.6%

FATE FATE THERAPEUTICS INC 1.0%

Value $11.69M Shares 2,050,000 Est. Cost $17.49 Unrealized -65.5%

IPSC CENTURY THERAPEUTICS INC 0.9%

Value $11.13M Shares 3,206,380 Est. Cost $25.37 Unrealized -82.7%

TWST TWIST BIOSCIENCE CORP 0.9%

Value $10.56M Shares 700,000 Est. Cost $30.77 Unrealized -28.2%

ABSI ABSCI CORPORATION 0.8%

Value $9.438M Shares 5,393,260 Est. Cost $19.41 Unrealized -87.5%

PRME PRIME MEDICINE INC 0.7%

Value $9.033M Shares 734,350 Est. Cost $18.06 Unrealized -9.8%

— DICE THERAPEUTICS INC 0.7%

Value $8.882M Shares 310,000 Est. Cost $30.01 Unrealized —

OPRX OPTIMIZERX CORP 0.6%

Value $7.315M Shares 500,000 Est. Cost $17.02 Unrealized -1.7%

INCY INCYTE CORP 0.5%

Value $5.601M Shares 77,500 Est. Cost $76.52 Unrealized +2.2%

GLUE MONTE ROSA THERAPEUTICS INC 0.3%

Value $3.98M Shares 510,882 Est. Cost $20.37 Unrealized -65.9%

TNGX TANGO THERAPEUTICS INC 0.3%

Value $3.95M Shares 1,000,000 Est. Cost $5.80 Unrealized 0.0%

SRPT SAREPTA THERAPEUTICS INC 0.3%

Value $3.446M Shares 25,000 Est. Cost $99.50 Unrealized +30.4%

— SINGULAR GENOMICS SYSTEMS IN 0.1%

Value $1.628M Shares 1,345,722 Est. Cost $18.57 Unrealized —

— INVITAE CORP 0.1%

Value $1.402M Shares 1,038,388 Est. Cost $330.76 Unrealized —

— EXSCIENTIA PLC 0.1%

Value $1.134M Shares 213,900 Est. Cost $19.76 Unrealized —

LIANY LIANBIO 0.0%

Value $403K Shares 206,415 Est. Cost $6.16 Unrealized —

— KRONOS BIO INC 0.0%

Value $181K Shares 123,839 Est. Cost $29.87 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
BLFS	BIOLIFE SOLUTIONS INC	7,571,535	$165M	13.6%	$20.20	+11.3%	COM NEW	09062W204
SRPT	SAREPTA THERAPEUTICS INC	1,160,000	$160M	13.2%	$99.50	+30.4%	COM	803607100
RLAY	RELAY THERAPEUTICS INC	5,698,574	$93.86M	7.7%	$26.85	-33.2%	COM	75943R102
—	EQRX INC	39,527,669	$76.68M	6.3%	$6.82	—	COM	26886C107
ILMN	ILLUMINA INC	275,000	$63.95M	5.3%	$197.84	+3.4%	COM	452327109
ALNY	ALNYLAM PHARMACEUTICALS INC	270,000	$54.09M	4.5%	$110.93	+89.5%	COM	02043Q107
NTLA	INTELLIA THERAPEUTICS INC	1,275,000	$47.52M	3.9%	$44.50	-11.9%	COM	45826J105
PLRX	PLIANT THERAPEUTICS INC	1,675,000	$44.55M	3.7%	$20.11	+41.6%	COM	729139105
RVMD	REVOLUTION MEDICINES INC	1,810,000	$39.2M	3.2%	$29.92	-17.7%	COM	76155X100
EXAS	EXACT SCIENCES CORP	565,000	$38.31M	3.2%	$81.07	-20.7%	COM	30063P105
—	GENEDX HOLDINGS CORP	102,151,785	$37.29M	3.1%	$0.82	—	COM CL A	81663L101
—	SOMALOGIC INC	12,604,275	$32.14M	2.6%	$12.23	—	CLASS A COM	83444K105
—	VERVE THERAPEUTICS INC	2,120,571	$30.58M	2.5%	$59.19	—	COM	92539P101
—	BLUEPRINT MEDICINES CORP	670,000	$30.14M	2.5%	$3820.05	—	COM	09627Y109
DNLI	DENALI THERAPEUTICS INC	1,300,000	$29.95M	2.5%	$29.48	-6.7%	COM	24823R105
MXCT	MAXCYTE INC	4,925,000	$24.38M	2.0%	$15.08	-67.3%	COM	57777K106
—	2SEVENTY BIO INC	2,023,913	$20.64M	1.7%	$11.78	—	COMMON STOCK	901384107
ABCL	ABCELLERA BIOLOGICS INC	2,520,000	$19M	1.6%	$10.18	-10.8%	COM	00288U106
—	MIRATI THERAPEUTICS INC	510,000	$18.96M	1.6%	$59.13	—	COM	60468T105
FDMT	4D MOLECULAR THERAPEUTICS IN	1,070,000	$18.39M	1.5%	$17.09	+13.8%	COM	35104E100
BEAM	BEAM THERAPEUTICS INC	570,000	$17.45M	1.4%	$58.84	-32.9%	COM	07373V105
TNYA	TENAYA THERAPEUTICS INC	6,078,860	$17.32M	1.4%	$13.68	-79.5%	COM	87990A106
GPCR	STRUCTURE THERAPEUTICS INC	677,017	$16.11M	1.3%	$23.79	—	SPONSORED ADS	86366E106
—	PROMETHEUS BIOSCIENCES INC	150,000	$16.1M	1.3%	$110.00	—	COM	74349U108
RNAM	AVIDITY BIOSCIENCES INC	850,000	$13.05M	1.1%	$14.91	+47.6%	COM	05370A108
FATE	FATE THERAPEUTICS INC	2,050,000	$11.69M	1.0%	$17.49	-65.5%	COM	31189P102
IPSC	CENTURY THERAPEUTICS INC	3,206,380	$11.13M	0.9%	$25.37	-82.7%	COM	15673T100
TWST	TWIST BIOSCIENCE CORP	700,000	$10.56M	0.9%	$30.77	-28.2%	COM	90184D100
ABSI	ABSCI CORPORATION	5,393,260	$9.438M	0.8%	$19.41	-87.5%	COM	00091E109
PRME	PRIME MEDICINE INC	734,350	$9.033M	0.7%	$18.06	-9.8%	COM	74168J101
—	DICE THERAPEUTICS INC	310,000	$8.882M	0.7%	$30.01	—	COM	23345J104
OPRX	OPTIMIZERX CORP	500,000	$7.315M	0.6%	$17.02	-1.7%	COM NEW	68401U204
INCY	INCYTE CORP	77,500	$5.601M	0.5%	$76.52	+2.2%	COM	45337C102
GLUE	MONTE ROSA THERAPEUTICS INC	510,882	$3.98M	0.3%	$20.37	-65.9%	COM	61225M102
TNGX	TANGO THERAPEUTICS INC	1,000,000	$3.95M	0.3%	$5.80	0.0%	COM	87583X109
SRPT	SAREPTA THERAPEUTICS INC	25,000	$3.446M	0.3%	$99.50	+30.4%	Call	803607100
—	SINGULAR GENOMICS SYSTEMS IN	1,345,722	$1.628M	0.1%	$18.57	—	COM	82933R100
—	INVITAE CORP	1,038,388	$1.402M	0.1%	$330.76	—	COM	46185L103
—	EXSCIENTIA PLC	213,900	$1.134M	0.1%	$19.76	—	ADS	30223G102
LIANY	LIANBIO	206,415	$403K	0.0%	$6.16	—	SPONSORED ADS	53000N108
—	KRONOS BIO INC	123,839	$181K	0.0%	$29.87	—	COM	50107A104