GREAT POINT PARTNERS LLC Quant / Systematic

CIK: 0001281446 · Show all filings

Period: Q4 2014 (← Previous) (Next →)

Filing Date: Feb 17, 2015

Total Value ($000): $207,762 (100.0% shares, 0.0% debt)

Holdings (28)

— CONNECTURE INC 23.9%

Value ($000) $49,582 Shares 5,502,965 Est. Cost $9.01 Unrealized —

— HYPERION THERAPEUTICS INC 11.5%

Value ($000) $23,953 Shares 998,066 Est. Cost $25.57 Unrealized —

— ALIMERA SCIENCES INC 7.0%

Value ($000) $14,514 Shares 2,619,853 Est. Cost $6.86 Unrealized —

— OCERA THERAPEUTICS INC 6.0%

Value ($000) $12,509 Shares 1,963,778 Est. Cost $6.20 Unrealized —

— DERMA SCIENCES INC 5.3%

Value ($000) $11,038 Shares 1,185,632 Est. Cost $12.35 Unrealized —

INFIQ INFINITY PHARMACEUTICALS INC 5.1%

Value ($000) $10,556 Shares 625,000 Est. Cost $12.26 Unrealized +18.7%

— ENDOLOGIX INC 4.8%

Value ($000) $9,939 Shares 650,000 Est. Cost $11.52 Unrealized —

AUPH AURINIA PHARMACEUTICALS INC 4.3%

Value ($000) $8,883 Shares 2,485,576 Est. Cost $3.55 Unrealized -0.9%

— ARROWHEAD RESH CORP 4.0%

Value ($000) $8,316 Shares 1,126,835 Est. Cost $7.38 Unrealized —

— ARADIGM CORP 3.7%

Value ($000) $7,623 Shares 1,002,962 Est. Cost $8.85 Unrealized —

EBS EMERGENT BIOSOLUTIONS INC 3.3%

Value ($000) $6,808 Shares 250,000 Est. Cost $22.90 Unrealized +4.1%

VCEL VERICEL CORP 3.2%

Value ($000) $6,597 Shares 2,170,000 Est. Cost $2.85 Unrealized 0.0%

— SYNTHETIC BIOLOGICS INC 2.8%

Value ($000) $5,839 Shares 3,998,941 Est. Cost $1.46 Unrealized —

VCYT VERACYTE INC 2.6%

Value ($000) $5,356 Shares 554,426 Est. Cost $13.38 Unrealized -41.7%

— TENAX THERAPEUTICS INC 2.0%

Value ($000) $4,257 Shares 1,108,593 Est. Cost $3.93 Unrealized —

— AGENUS INC 1.8%

Value ($000) $3,654 Shares 920,300 Est. Cost $3.97 Unrealized —

OM2 ORTHOFIX INTL N V 1.6%

Value ($000) $3,307 Shares 110,000 Est. Cost $31.18 Unrealized —

EXEL EXELIXIS, INC 1.5%

Value ($000) $3,217 Shares 2,233,711 Est. Cost $3.21 Unrealized -51.5%

— ADAMAS PHARMACEUTICALS INC 1.4%

Value ($000) $2,967 Shares 170,816 Est. Cost $17.37 Unrealized —

— VICAL INC 1.1%

Value ($000) $2,224 Shares 2,117,941 Est. Cost $1.19 Unrealized —

— ONCONOVA THERAPEUTICS INC 0.9%

Value ($000) $1,820 Shares 553,079 Est. Cost $4.14 Unrealized —

— BELLICUM PHARMACEUTICALS INC 0.6%

Value ($000) $1,152 Shares 50,000 Est. Cost $23.04 Unrealized —

NBIX NEUROCRINE BIOSCIENCES INC 0.5%

Value ($000) $1,032 Shares 46,200 Est. Cost $15.34 Unrealized +23.5%

— MEI PHARMA INC 0.3%

Value ($000) $673 Shares 157,661 Est. Cost $11.25 Unrealized —

— STREAMLINE HEALTH SOLUTIONS 0.3%

Value ($000) $656 Shares 151,611 Est. Cost $6.45 Unrealized —

— ZOGENIX INC 0.2%

Value ($000) $503 Shares 367,502 Est. Cost $1.37 Unrealized —

— ANTHERA PHARMACEUTICALS INC 0.2%

Value ($000) $395 Shares 250,000 Est. Cost $3.35 Unrealized —

— PROTALIX BIOTHERAPEUTICS INC 0.2%

Value ($000) $392 Shares 213,215 Est. Cost $1.84 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
—	CONNECTURE INC	5,502,965	$49,582	23.9%	$9.01	—	COM	20786J106
—	HYPERION THERAPEUTICS INC	998,066	$23,953	11.5%	$25.57	—	COM	44915N101
—	ALIMERA SCIENCES INC	2,619,853	$14,514	7.0%	$6.86	—	COM	016259103
—	OCERA THERAPEUTICS INC	1,963,778	$12,509	6.0%	$6.20	—	COM	67552A108
—	DERMA SCIENCES INC	1,185,632	$11,038	5.3%	$12.35	—	COM PAR $.01	249827502
INFIQ	INFINITY PHARMACEUTICALS INC	625,000	$10,556	5.1%	$12.26	+18.7%	COM	45665G303
—	ENDOLOGIX INC	650,000	$9,939	4.8%	$11.52	—	COM	29266S106
AUPH	AURINIA PHARMACEUTICALS INC	2,485,576	$8,883	4.3%	$3.55	-0.9%	COM	05156V102
—	ARROWHEAD RESH CORP	1,126,835	$8,316	4.0%	$7.38	—	COM NEW	042797209
—	ARADIGM CORP	1,002,962	$7,623	3.7%	$8.85	—	COM NO PAR NEW	038505400
EBS	EMERGENT BIOSOLUTIONS INC	250,000	$6,808	3.3%	$22.90	+4.1%	COM	29089Q105
VCEL	VERICEL CORP	2,170,000	$6,597	3.2%	$2.85	0.0%	COM	92346J108
—	SYNTHETIC BIOLOGICS INC	3,998,941	$5,839	2.8%	$1.46	—	COM	87164U102
VCYT	VERACYTE INC	554,426	$5,356	2.6%	$13.38	-41.7%	COM	92337F107
—	TENAX THERAPEUTICS INC	1,108,593	$4,257	2.0%	$3.93	—	COM	88032L100
—	AGENUS INC	920,300	$3,654	1.8%	$3.97	—	COM NEW	00847G705
OM2	ORTHOFIX INTL N V	110,000	$3,307	1.6%	$31.18	—	COM	N6748L102
EXEL	EXELIXIS, INC	2,233,711	$3,217	1.5%	$3.21	-51.5%	COM	30161Q104
—	ADAMAS PHARMACEUTICALS INC	170,816	$2,967	1.4%	$17.37	—	COM	00548A106
—	VICAL INC	2,117,941	$2,224	1.1%	$1.19	—	COM	925602104
—	ONCONOVA THERAPEUTICS INC	553,079	$1,820	0.9%	$4.14	—	COM	68232V108
—	BELLICUM PHARMACEUTICALS INC	50,000	$1,152	0.6%	$23.04	—	COM	079481107
NBIX	NEUROCRINE BIOSCIENCES INC	46,200	$1,032	0.5%	$15.34	+23.5%	Put	64125C109
—	MEI PHARMA INC	157,661	$673	0.3%	$11.25	—	COM NEW	55279B202
—	STREAMLINE HEALTH SOLUTIONS	151,611	$656	0.3%	$6.45	—	COM	86323X106
—	ZOGENIX INC	367,502	$503	0.2%	$1.37	—	COM	98978L105
—	ANTHERA PHARMACEUTICALS INC	250,000	$395	0.2%	$3.35	—	COM NEW	03674U201
—	PROTALIX BIOTHERAPEUTICS INC	213,215	$392	0.2%	$1.84	—	COM	74365A101