GREAT POINT PARTNERS LLC Quant / Systematic

Location: Greenwich, CT

CIK: 0001281446 · Show all filings

Period: Q4 2017 (← Previous) (Next →)

Filing Date: Feb 14, 2018

Total Value: $586M (100.0% shares, 0.0% debt)

Holdings (39)

— ZOGENIX INC CMN 7.7%

Value $44.91M Shares 1,121,331 Est. Cost $14.10 Unrealized —

— ARENA PHARMACEUTICALS, INC. CMN 6.8%

Value $39.99M Shares 1,177,119 Est. Cost $16.87 Unrealized —

KURA KURA ONCOLOGY, INC. CMN 5.7%

Value $33.62M Shares 2,197,283 Est. Cost $10.47 Unrealized +40.7%

— SAGE THERAPEUTICS, INC CMN 5.6%

Value $32.94M Shares 200,000 Est. Cost $94.62 Unrealized —

— GLOBAL BLOOD THERAPEUTICS, INC. CMN 5.4%

Value $31.61M Shares 803,205 Est. Cost $28.28 Unrealized —

NBIX NEUROCRINE BIOSCIENCES INC CMN 5.3%

Value $31.04M Shares 400,000 Est. Cost $43.70 Unrealized +56.1%

— RIGEL PHARMACEUTICALS INC CMN 5.2%

Value $30.61M Shares 7,888,581 Est. Cost $3.31 Unrealized —

— FOAMIX PHARMACEUTICALS LIMITED CMN 4.9%

Value $28.74M Shares 4,781,708 Est. Cost $7.50 Unrealized —

BCRX BIOCRYST PHARMACEUTICALS INC CMN 4.0%

Value $23.33M Shares 4,751,883 Est. Cost $4.94 Unrealized -1.9%

— AIMMUNE THERAPEUTICS, INC. CMN 3.7%

Value $21.69M Shares 573,550 Est. Cost $23.50 Unrealized —

— SPARK THERAPEUTICS INC CMN 3.6%

Value $21.13M Shares 410,900 Est. Cost $51.42 Unrealized —

PTCT PTC THERAPEUTICS, INC. CMN 3.1%

Value $18.11M Shares 1,085,800 Est. Cost $12.42 Unrealized +36.3%

NVCR NOVOCURE, LTD. CMN 3.0%

Value $17.76M Shares 879,286 Est. Cost $19.34 Unrealized -0.4%

— CONCERT PHARMACEUTICALS INC CMN 3.0%

Value $17.32M Shares 669,472 Est. Cost $17.06 Unrealized —

— NEWLINK GENETICS CORPORATION CMN 2.7%

Value $16.11M Shares 1,987,099 Est. Cost $8.11 Unrealized —

IOVA IOVANCE BIOTHERAPEUTICS, INC. CMN 2.7%

Value $16M Shares 2,000,000 Est. Cost $6.33 Unrealized +26.8%

— AXOVANT SCIENCES LTD CMN 2.6%

Value $15.02M Shares 2,850,000 Est. Cost $5.28 Unrealized —

CPRX CATALYST PHARMACEUTICAL INC.CMN 2.5%

Value $14.93M Shares 3,817,288 Est. Cost $3.30 Unrealized 0.0%

— BIOHAVEN PHARMACEUTICAL HOLDING CO LTD. CMN 2.3%

Value $13.49M Shares 500,192 Est. Cost $26.98 Unrealized —

SVRA SAVARA INC CMN 2.2%

Value $12.9M Shares 869,500 Est. Cost $11.47 Unrealized 0.0%

VNDA VANDA PHARMACEUTICALS INC. CMN 2.1%

Value $12.12M Shares 797,531 Est. Cost $12.36 Unrealized +20.0%

WVE WAVE LIFE SCIENCES PTE LTD CMN 2.0%

Value $11.62M Shares 331,085 Est. Cost $29.15 Unrealized 0.0%

— REVANCE THERAPEUTICS INC CMN 1.8%

Value $10.72M Shares 300,000 Est. Cost $35.75 Unrealized —

— GW PHARMACEUTICALS PLC ADR CMN 1.7%

Value $9.901M Shares 75,000 Est. Cost $132.01 Unrealized —

— GLOBAL BLOOD THERAPEUTICS, INC. CMN 1.3%

Value $7.87M Shares 200,000 Est. Cost $28.28 Unrealized —

— DBV TECHNOLOGIES SA SPONSORED ADR CMN 1.3%

Value $7.703M Shares 313,140 Est. Cost $35.48 Unrealized —

— ACCELERON PHARMA INC CMN 1.3%

Value $7.347M Shares 173,124 Est. Cost $28.27 Unrealized —

INCY INCYTE CORPORATION CMN 1.1%

Value $6.66M Shares 70,323 Est. Cost $104.52 Unrealized 0.0%

— CIDARA THERAPEUTICS, INC. 0.9%

Value $5.44M Shares 800,000 Est. Cost $6.80 Unrealized —

— ACORDA THERAPEUTICS INC CMN 0.7%

Value $4.29M Shares 200,000 Est. Cost — Unrealized —

— CORBUS PHARMACEUTICALS HOLDINGS, INC. CMN 0.7%

Value $4.26M Shares 600,000 Est. Cost $7.10 Unrealized —

— AMARIN CORPORATION PLC SPONSORED ADR CMN 0.7%

Value $4.238M Shares 1,056,825 Est. Cost $4.03 Unrealized —

— JOUNCE THERAPEUTICS INC CMN 0.6%

Value $3.732M Shares 292,673 Est. Cost $12.75 Unrealized —

— KADMON HOLDINGS INC CMN 0.5%

Value $3.042M Shares 840,303 Est. Cost $3.62 Unrealized —

— MYOVANT SCIENCES LTD CMN 0.3%

Value $2.029M Shares 160,530 Est. Cost $12.34 Unrealized —

— SELECTA BIOSCIENCES, INC. 0.3%

Value $1.745M Shares 177,900 Est. Cost $19.86 Unrealized —

— DERMIRA INC CMN 0.2%

Value $1.214M Shares 43,637 Est. Cost $27.82 Unrealized —

— CONNECTURE INC 0.1%

Value $660K Shares 4,127,232 Est. Cost $9.01 Unrealized —

— STREAMLINE HEALTH SOLUTNS, INC CMN 0.0%

Value $220K Shares 130,137 Est. Cost $6.45 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	ZOGENIX INC CMN	1,121,331	$44.91M	7.7%	$14.10	—	COM NEW	98978L204
—	ARENA PHARMACEUTICALS, INC. CMN	1,177,119	$39.99M	6.8%	$16.87	—	COM NEW	040047607
KURA	KURA ONCOLOGY, INC. CMN	2,197,283	$33.62M	5.7%	$10.47	+40.7%	COM	50127T109
—	SAGE THERAPEUTICS, INC CMN	200,000	$32.94M	5.6%	$94.62	—	COM	78667J108
—	GLOBAL BLOOD THERAPEUTICS, INC. CMN	803,205	$31.61M	5.4%	$28.28	—	COM	37890U108
NBIX	NEUROCRINE BIOSCIENCES INC CMN	400,000	$31.04M	5.3%	$43.70	+56.1%	COM	64125C109
—	RIGEL PHARMACEUTICALS INC CMN	7,888,581	$30.61M	5.2%	$3.31	—	COM NEW	766559603
—	FOAMIX PHARMACEUTICALS LIMITED CMN	4,781,708	$28.74M	4.9%	$7.50	—	SHS	M46135105
BCRX	BIOCRYST PHARMACEUTICALS INC CMN	4,751,883	$23.33M	4.0%	$4.94	-1.9%	COM	09058V103
—	AIMMUNE THERAPEUTICS, INC. CMN	573,550	$21.69M	3.7%	$23.50	—	COM	00900T107
—	SPARK THERAPEUTICS INC CMN	410,900	$21.13M	3.6%	$51.42	—	COM	84652J103
PTCT	PTC THERAPEUTICS, INC. CMN	1,085,800	$18.11M	3.1%	$12.42	+36.3%	COM	69366J200
NVCR	NOVOCURE, LTD. CMN	879,286	$17.76M	3.0%	$19.34	-0.4%	ORD SHS	G6674U108
—	CONCERT PHARMACEUTICALS INC CMN	669,472	$17.32M	3.0%	$17.06	—	COM	206022105
—	NEWLINK GENETICS CORPORATION CMN	1,987,099	$16.11M	2.7%	$8.11	—	COM	651511107
IOVA	IOVANCE BIOTHERAPEUTICS, INC. CMN	2,000,000	$16M	2.7%	$6.33	+26.8%	COM	462260100
—	AXOVANT SCIENCES LTD CMN	2,850,000	$15.02M	2.6%	$5.28	—	COM	G0750W104
CPRX	CATALYST PHARMACEUTICAL INC.CMN	3,817,288	$14.93M	2.5%	$3.30	0.0%	COM	14888U101
—	BIOHAVEN PHARMACEUTICAL HOLDING CO LTD. CMN	500,192	$13.49M	2.3%	$26.98	—	COM	G11196105
SVRA	SAVARA INC CMN	869,500	$12.9M	2.2%	$11.47	0.0%	COM	805111101
VNDA	VANDA PHARMACEUTICALS INC. CMN	797,531	$12.12M	2.1%	$12.36	+20.0%	COM	921659108
WVE	WAVE LIFE SCIENCES PTE LTD CMN	331,085	$11.62M	2.0%	$29.15	0.0%	SHS	Y95308105
—	REVANCE THERAPEUTICS INC CMN	300,000	$10.72M	1.8%	$35.75	—	COM	761330109
—	GW PHARMACEUTICALS PLC ADR CMN	75,000	$9.901M	1.7%	$132.01	—	ADS	36197T103
—	GLOBAL BLOOD THERAPEUTICS, INC. CMN	200,000	$7.87M	1.3%	$28.28	—	Call	37890U108
—	DBV TECHNOLOGIES SA SPONSORED ADR CMN	313,140	$7.703M	1.3%	$35.48	—	SPONSORED ADR	23306J101
—	ACCELERON PHARMA INC CMN	173,124	$7.347M	1.3%	$28.27	—	COM	00434H108
INCY	INCYTE CORPORATION CMN	70,323	$6.66M	1.1%	$104.52	0.0%	COM	45337C102
—	CIDARA THERAPEUTICS, INC.	800,000	$5.44M	0.9%	$6.80	—	COM	171757107
—	ACORDA THERAPEUTICS INC CMN	200,000	$4.29M	0.7%	—	—	Put	00484M106
—	CORBUS PHARMACEUTICALS HOLDINGS, INC. CMN	600,000	$4.26M	0.7%	$7.10	—	COM	21833P103
—	AMARIN CORPORATION PLC SPONSORED ADR CMN	1,056,825	$4.238M	0.7%	$4.03	—	SPONS ADR NEW	023111206
—	JOUNCE THERAPEUTICS INC CMN	292,673	$3.732M	0.6%	$12.75	—	COM	481116101
—	KADMON HOLDINGS INC CMN	840,303	$3.042M	0.5%	$3.62	—	COM	48283N106
—	MYOVANT SCIENCES LTD CMN	160,530	$2.029M	0.3%	$12.34	—	COM	G637AM102
—	SELECTA BIOSCIENCES, INC.	177,900	$1.745M	0.3%	$19.86	—	COM	816212104
—	DERMIRA INC CMN	43,637	$1.214M	0.2%	$27.82	—	COM	24983L104
—	CONNECTURE INC	4,127,232	$660K	0.1%	$9.01	—	COM	20786J106
—	STREAMLINE HEALTH SOLUTNS, INC CMN	130,137	$220K	0.0%	$6.45	—	COM	86323X106