GREAT POINT PARTNERS LLC Quant / Systematic

CIK: 0001281446 · Show all filings

Period: Q3 2017 (← Previous) (Next →)

Filing Date: Nov 14, 2017

Total Value ($000): $514,030 (100.0% shares, 0.0% debt)

Holdings (37)

— ZOGENIX INC 7.0%

Value ($000) $35,798 Shares 1,021,331 Est. Cost $11.56 Unrealized —

UTHR UNITED THERAPEUTICS CORP DEL 6.8%

Value ($000) $35,157 Shares 300,000 Est. Cost — Unrealized —

— ARENA PHARMACEUTICALS INC 6.7%

Value ($000) $34,624 Shares 1,357,800 Est. Cost $16.87 Unrealized —

— CONCERT PHARMACEUTICALS INC 5.8%

Value ($000) $29,592 Shares 2,006,211 Est. Cost $17.06 Unrealized —

ALNY ALNYLAM PHARMACEUTICALS INC 5.7%

Value ($000) $29,373 Shares 250,000 Est. Cost $62.99 Unrealized +35.5%

NBIX NEUROCRINE BIOSCIENCES INC 5.7%

Value ($000) $29,108 Shares 475,000 Est. Cost $43.70 Unrealized +20.7%

— FOAMIX PHARMACEUTICALS LTD 5.2%

Value ($000) $26,538 Shares 4,781,708 Est. Cost $7.50 Unrealized —

KURA KURA ONCOLOGY INC 5.1%

Value ($000) $26,176 Shares 1,750,887 Est. Cost $9.39 Unrealized 0.0%

— RIGEL PHARMACEUTICALS INC 4.5%

Value ($000) $23,128 Shares 9,105,691 Est. Cost $3.31 Unrealized —

PTCT PTC THERAPEUTICS INC 4.3%

Value ($000) $22,011 Shares 1,100,000 Est. Cost $12.42 Unrealized +57.4%

— DBV TECHNOLOGIES SA 3.7%

Value ($000) $19,136 Shares 450,888 Est. Cost $35.48 Unrealized —

— ZOGENIX INC 3.4%

Value ($000) $17,525 Shares 500,000 Est. Cost $11.56 Unrealized —

— GLOBAL BLOOD THERAPEUTICS IN 3.4%

Value ($000) $17,403 Shares 560,498 Est. Cost $23.49 Unrealized —

— SELECTA BIOSCIENCES INC 3.2%

Value ($000) $16,459 Shares 901,847 Est. Cost $19.86 Unrealized —

IOVA IOVANCE BIOTHERAPEUTICS INC 3.0%

Value ($000) $15,500 Shares 2,000,000 Est. Cost $6.33 Unrealized -0.0%

— IGNYTA INC 3.0%

Value ($000) $15,336 Shares 1,241,752 Est. Cost $5.55 Unrealized —

— ZOGENIX INC 2.6%

Value ($000) $13,144 Shares 375,000 Est. Cost $11.56 Unrealized —

— AIMMUNE THERAPEUTICS INC 2.4%

Value ($000) $12,395 Shares 500,000 Est. Cost $21.39 Unrealized —

SRPT SAREPTA THERAPEUTICS INC 2.2%

Value ($000) $11,340 Shares 250,000 Est. Cost $39.97 Unrealized 0.0%

— SYNERGY PHARMACEUTICALS DEL 1.8%

Value ($000) $9,493 Shares 3,273,509 Est. Cost $4.54 Unrealized —

PTCT PTC THERAPEUTICS INC 1.8%

Value ($000) $9,205 Shares 460,000 Est. Cost $12.42 Unrealized +57.4%

VNDA VANDA PHARMACEUTICALS INC 1.7%

Value ($000) $8,906 Shares 497,531 Est. Cost $10.87 Unrealized +53.9%

BCRX BIOCRYST PHARMACEUTICALS 1.7%

Value ($000) $8,580 Shares 1,637,332 Est. Cost $5.12 Unrealized 0.0%

— SAGE THERAPEUTICS INC 1.3%

Value ($000) $6,822 Shares 109,500 Est. Cost $36.69 Unrealized —

— ACCELERON PHARMA INC 1.2%

Value ($000) $6,344 Shares 170,000 Est. Cost $28.01 Unrealized —

— BOVIE MEDICAL CORP 1.2%

Value ($000) $6,184 Shares 1,829,441 Est. Cost $2.83 Unrealized —

— ADAMAS PHARMACEUTICALS INC 1.1%

Value ($000) $5,427 Shares 256,340 Est. Cost $18.31 Unrealized —

— SERES THERAPEUTICS INC 0.9%

Value ($000) $4,411 Shares 275,000 Est. Cost — Unrealized —

— AMARIN CORPORATION PLC 0.7%

Value ($000) $3,699 Shares 1,056,825 Est. Cost $4.03 Unrealized —

— MYOVANT SCIENCES LTD 0.7%

Value ($000) $3,527 Shares 228,008 Est. Cost $12.34 Unrealized —

NVCR NOVOCURE LTD 0.7%

Value ($000) $3,527 Shares 177,666 Est. Cost $19.65 Unrealized 0.0%

— SUNESIS PHARMACEUTICALS INC 0.6%

Value ($000) $2,828 Shares 1,457,712 Est. Cost $4.10 Unrealized —

— CONNECTURE INC 0.5%

Value ($000) $2,765 Shares 4,127,232 Est. Cost $9.01 Unrealized —

— AGILE THERAPEUTICS INC 0.3%

Value ($000) $1,620 Shares 363,299 Est. Cost $4.46 Unrealized —

ARDX ARDELYX INC 0.1%

Value ($000) $691 Shares 123,316 Est. Cost $5.27 Unrealized 0.0%

— STREAMLINE HEALTH SOLUTIONS 0.0%

Value ($000) $191 Shares 130,137 Est. Cost $6.45 Unrealized —

— AXOVANT SCIENCES LTD 0.0%

Value ($000) $67 Shares 9,679 Est. Cost $6.92 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
—	ZOGENIX INC	1,021,331	$35,798	7.0%	$11.56	—	COM NEW	98978L204
UTHR	UNITED THERAPEUTICS CORP DEL	300,000	$35,157	6.8%	—	—	Call	91307C102
—	ARENA PHARMACEUTICALS INC	1,357,800	$34,624	6.7%	$16.87	—	COM NEW	040047607
—	CONCERT PHARMACEUTICALS INC	2,006,211	$29,592	5.8%	$17.06	—	COM	206022105
ALNY	ALNYLAM PHARMACEUTICALS INC	250,000	$29,373	5.7%	$62.99	+35.5%	Put	02043Q107
NBIX	NEUROCRINE BIOSCIENCES INC	475,000	$29,108	5.7%	$43.70	+20.7%	COM	64125C109
—	FOAMIX PHARMACEUTICALS LTD	4,781,708	$26,538	5.2%	$7.50	—	SHS	M46135105
KURA	KURA ONCOLOGY INC	1,750,887	$26,176	5.1%	$9.39	0.0%	COM	50127T109
—	RIGEL PHARMACEUTICALS INC	9,105,691	$23,128	4.5%	$3.31	—	COM NEW	766559603
PTCT	PTC THERAPEUTICS INC	1,100,000	$22,011	4.3%	$12.42	+57.4%	COM	69366J200
—	DBV TECHNOLOGIES SA	450,888	$19,136	3.7%	$35.48	—	SPONSORED ADR	23306J101
—	ZOGENIX INC	500,000	$17,525	3.4%	$11.56	—	Call	98978L204
—	GLOBAL BLOOD THERAPEUTICS IN	560,498	$17,403	3.4%	$23.49	—	COM	37890U108
—	SELECTA BIOSCIENCES INC	901,847	$16,459	3.2%	$19.86	—	COM	816212104
IOVA	IOVANCE BIOTHERAPEUTICS INC	2,000,000	$15,500	3.0%	$6.33	-0.0%	COM	462260100
—	IGNYTA INC	1,241,752	$15,336	3.0%	$5.55	—	COM	451731103
—	ZOGENIX INC	375,000	$13,144	2.6%	$11.56	—	Put	98978L204
—	AIMMUNE THERAPEUTICS INC	500,000	$12,395	2.4%	$21.39	—	COM	00900T107
SRPT	SAREPTA THERAPEUTICS INC	250,000	$11,340	2.2%	$39.97	0.0%	COM	803607100
—	SYNERGY PHARMACEUTICALS DEL	3,273,509	$9,493	1.8%	$4.54	—	COM NEW	871639308
PTCT	PTC THERAPEUTICS INC	460,000	$9,205	1.8%	$12.42	+57.4%	Call	69366J200
VNDA	VANDA PHARMACEUTICALS INC	497,531	$8,906	1.7%	$10.87	+53.9%	COM	921659108
BCRX	BIOCRYST PHARMACEUTICALS	1,637,332	$8,580	1.7%	$5.12	0.0%	COM	09058V103
—	SAGE THERAPEUTICS INC	109,500	$6,822	1.3%	$36.69	—	COM	78667J108
—	ACCELERON PHARMA INC	170,000	$6,344	1.2%	$28.01	—	COM	00434H108
—	BOVIE MEDICAL CORP	1,829,441	$6,184	1.2%	$2.83	—	COM	10211F100
—	ADAMAS PHARMACEUTICALS INC	256,340	$5,427	1.1%	$18.31	—	COM	00548A106
—	SERES THERAPEUTICS INC	275,000	$4,411	0.9%	—	—	Put	81750R102
—	AMARIN CORPORATION PLC	1,056,825	$3,699	0.7%	$4.03	—	SPONS ADR NEW	023111206
—	MYOVANT SCIENCES LTD	228,008	$3,527	0.7%	$12.34	—	COM	G637AM102
NVCR	NOVOCURE LTD	177,666	$3,527	0.7%	$19.65	0.0%	ORD SHS	G6674U108
—	SUNESIS PHARMACEUTICALS INC	1,457,712	$2,828	0.6%	$4.10	—	COM PAR	867328700
—	CONNECTURE INC	4,127,232	$2,765	0.5%	$9.01	—	COM	20786J106
—	AGILE THERAPEUTICS INC	363,299	$1,620	0.3%	$4.46	—	COM	00847L100
ARDX	ARDELYX INC	123,316	$691	0.1%	$5.27	0.0%	COM	039697107
—	STREAMLINE HEALTH SOLUTIONS	130,137	$191	0.0%	$6.45	—	COM	86323X106
—	AXOVANT SCIENCES LTD	9,679	$67	0.0%	$6.92	—	COM	G0750W104