Stonepine Capital Management, LLC Quant / Systematic

Location: Bend, OR

CIK: 0001440771 · Show all filings

Period: Q4 2024 (← Previous) (Next →)

Filing Date: Feb 14, 2025

Total Value: $124M (100.0% shares, 0.0% debt)

Holdings (52)

ADMA ADMA BIOLOGICS INC 17.2%
Value $21.28M Shares 1,241,032 Share Price $17.15 * Est. Cost/Share $2.26 Unrealized @ Report Date +730.9%
EOLS EVOLUS INC 11.3%
Value $13.96M Shares 1,264,651 Share Price $11.04 * Est. Cost/Share $8.66 Unrealized @ Report Date +62.4%
TELA TELA BIO INC 5.7%
Value $7.106M Shares 2,353,099 Share Price $3.02 * Est. Cost/Share $4.41 Unrealized @ Report Date -36.3%
GLPG GALAPAGOS NV-SPON ADR 4.4%
Value $5.5M Shares 200,000 Share Price $27.50 Est. Cost/Share $34.61 Unrealized @ Report Date —
ZVRA ZEVRA THERAPEUTICS INC 4.0%
Value $4.985M Shares 597,700 Share Price $8.34 * Est. Cost/Share $6.78 Unrealized @ Report Date +25.9%
VSTM VERASTEM INC 3.6%
Value $4.498M Shares 870,000 Share Price $5.17 * Est. Cost/Share $2.71 Unrealized @ Report Date +45.1%
ACAD ACADIA PHARMACEUTICALS INC 3.3%
Value $4.037M Shares 220,000 Share Price $18.35 * Est. Cost/Share $16.61 Unrealized @ Report Date -2.8%
— OPTINOSE INC 3.2%
Value $3.932M Shares 588,657 Share Price $6.68 Est. Cost/Share $6.68 Unrealized @ Report Date —
ANIK ANIKA THERAPEUTICS INC 3.2%
Value $3.921M Shares 238,222 Share Price $16.46 * Est. Cost/Share $24.21 Unrealized @ Report Date -18.5%
— INDIVIOR PLC 3.1%
Value $3.791M Shares 305,000 Share Price $12.43 Est. Cost/Share $10.06 Unrealized @ Report Date —
ESTA ESTABLISHMENT LABS HOLDINGS 3.0%
Value $3.686M Shares 80,002 Share Price $46.07 * Est. Cost/Share $43.49 Unrealized @ Report Date +0.2%
IKT INHIBIKASE THERAPEUTICS INC 3.0%
Value $3.68M Shares 1,132,388 Share Price $3.25 * Est. Cost/Share $2.49 Unrealized @ Report Date 0.0%
URGN UROGEN PHARMA LTD 2.8%
Value $3.454M Shares 324,324 Share Price $10.65 * Est. Cost/Share $14.45 Unrealized @ Report Date -17.2%
XOMA XOMA CORP 2.7%
Value $3.303M Shares 125,700 Share Price $26.28 * Est. Cost/Share $19.74 Unrealized @ Report Date +48.0%
DAWN DAY ONE BIOPHARMACEUTICALS I 2.4%
Value $2.977M Shares 235,000 Share Price $12.67 * Est. Cost/Share $14.22 Unrealized @ Report Date -2.2%
IRWD IRONWOOD PHARMACEUTICALS INC 2.3%
Value $2.874M Shares 648,785 Share Price $4.43 * Est. Cost/Share $5.46 Unrealized @ Report Date -25.7%
— SCPHARMACEUTICALS INC 2.0%
Value $2.42M Shares 683,530 Share Price $3.54 Est. Cost/Share $4.81 Unrealized @ Report Date —
SRZN SURROZEN INC 1.6%
Value $1.969M Shares 137,200 Share Price $14.35 * Est. Cost/Share $9.90 Unrealized @ Report Date +7.2%
INO INOVIO PHARMACEUTICALS INC 1.6%
Value $1.921M Shares 1,050,000 Share Price $1.83 * Est. Cost/Share $4.43 Unrealized @ Report Date 0.0%
ENTA ENANTA PHARMACEUTICALS INC 1.5%
Value $1.908M Shares 331,900 Share Price $5.75 * Est. Cost/Share $9.59 Unrealized @ Report Date 0.0%
MYO MYOMO INC 1.4%
Value $1.767M Shares 274,426 Share Price $6.44 * Est. Cost/Share $4.60 Unrealized @ Report Date +5.7%
CALC CALCIMEDICA INC 1.3%
Value $1.66M Shares 468,793 Share Price $3.54 Est. Cost/Share $3.50 Unrealized @ Report Date 0.0%
ACRS ACLARIS THERAPEUTICS INC 1.3%
Value $1.645M Shares 663,405 Share Price $2.48 Est. Cost/Share $1.19 Unrealized @ Report Date +109.8%
PROF PROFOUND MEDICAL CORP 1.2%
Value $1.502M Shares 200,000 Share Price $7.51 * Est. Cost/Share $7.68 Unrealized @ Report Date 0.0%
JAZZ JAZZ PHARMACEUTICALS PLC US LISTED 1.0%
Value $1.232M Shares 10,000 Share Price $123.15 * Est. Cost/Share $109.58 Unrealized @ Report Date +7.6%
VIR VIR BIOTECHNOLOGY INC 1.0%
Value $1.205M Shares 164,106 Share Price $7.34 * Est. Cost/Share $7.89 Unrealized @ Report Date 0.0%
MIST MILESTONE PHARMACEUTICALS IN 1.0%
Value $1.18M Shares 500,000 Share Price $2.36 * Est. Cost/Share $1.62 Unrealized @ Report Date +5.7%
ANIP ANI PHARMACEUTICALS INC 0.9%
Value $1.128M Shares 20,400 Share Price $55.28 * Est. Cost/Share $57.41 Unrealized @ Report Date 0.0%
HRTX HERON THERAPEUTICS INC 0.9%
Value $1.071M Shares 700,000 Share Price $1.53 * Est. Cost/Share $1.62 Unrealized @ Report Date 0.0%
XGN EXAGEN INC 0.8%
Value $1.029M Shares 251,049 Share Price $4.10 * Est. Cost/Share $6.84 Unrealized @ Report Date -47.3%
— 2SEVENTY BIO INC 0.7%
Value $882K Shares 300,000 Share Price $2.94 Est. Cost/Share $3.24 Unrealized @ Report Date —
— ITEOS THERAPEUTICS INC 0.7%
Value $845K Shares 110,000 Share Price $7.68 Est. Cost/Share $8.37 Unrealized @ Report Date —
PMVP PMV PHARMACEUTICALS INC 0.7%
Value $809K Shares 535,805 Share Price $1.51 * Est. Cost/Share $1.58 Unrealized @ Report Date 0.0%
KZR KEZAR LIFE SCIENCES INC 0.6%
Value $739K Shares 110,000 Share Price $6.72 * Est. Cost/Share $7.45 Unrealized @ Report Date 0.0%
AYTU AYTU BIOPHARMA INC 0.6%
Value $693K Shares 407,549 Share Price $1.70 * Est. Cost/Share $2.00 Unrealized @ Report Date -8.6%
— ADICET BIO INC 0.5%
Value $673K Shares 700,000 Share Price $0.96 Est. Cost/Share $1.41 Unrealized @ Report Date —
KPRX KIORA PHARMACEUTICALS INC 0.5%
Value $663K Shares 200,970 Share Price $3.30 * Est. Cost/Share $3.90 Unrealized @ Report Date -11.5%
XERS XERIS BIOPHARMA HOLDINGS INC 0.5%
Value $618K Shares 182,317 Share Price $3.39 * Est. Cost/Share $3.22 Unrealized @ Report Date 0.0%
AQST AQUESTIVE THERAPEUTICS INC 0.5%
Value $570K Shares 160,000 Share Price $3.56 * Est. Cost/Share $4.61 Unrealized @ Report Date 0.0%
APRE APREA THERAPEUTICS INC 0.4%
Value $491K Shares 149,221 Share Price $3.29 Est. Cost/Share $5.01 Unrealized @ Report Date -33.3%
— ACELYRIN INC 0.3%
Value $417K Shares 132,870 Share Price $3.14 Est. Cost/Share $3.14 Unrealized @ Report Date —
CHRS COHERUS BIOSCIENCES INC 0.3%
Value $345K Shares 250,000 Share Price $1.38 * Est. Cost/Share $1.12 Unrealized @ Report Date 0.0%
PYPD POLYPID LTD 0.3%
Value $315K Shares 103,668 Share Price $3.04 * Est. Cost/Share $3.59 Unrealized @ Report Date -8.3%
— HILLEVAX INC 0.2%
Value $274K Shares 132,347 Share Price $2.07 Est. Cost/Share $2.07 Unrealized @ Report Date —
ANTX AN2 THERAPEUTICS INC 0.2%
Value $271K Shares 196,732 Share Price $1.38 * Est. Cost/Share $1.21 Unrealized @ Report Date 0.0%
VNDA VANDA PHARMACEUTICALS INC 0.1%
Value $120K Shares 25,000 Share Price $4.79 Est. Cost/Share $4.80 Unrealized @ Report Date 0.0%
— ELEVATION ONCOLOGY INC 0.1%
Value $113K Shares 200,000 Share Price $0.56 Est. Cost/Share $0.56 Unrealized @ Report Date —
ABVX ABIVAX SA 0.1%
Value $110K Shares 15,000 Share Price $7.32 Est. Cost/Share $7.32 Unrealized @ Report Date —
— ALIMERA SCIENCES INC CVR 0.1%
Value $107K Shares 2,408,469 Share Price $0.04 Est. Cost/Share $0.04 Unrealized @ Report Date —
ALLR ALLARITY THERAPEUTICS INC 0.1%
Value $78,728 Shares 67,289 Share Price $1.17 * Est. Cost/Share $1.33 Unrealized @ Report Date 0.0%
— REVANCE THERAPEUTICS INC 0.1%
Value $70,723 Shares 23,264 Share Price $3.04 Est. Cost/Share $4.23 Unrealized @ Report Date —
— AMARIN CORPORATION PLC -ADR 0.0%
Value $55,415 Shares 114,257 Share Price $0.49 Est. Cost/Share $0.49 Unrealized @ Report Date —