Stonepine Capital Management, LLC Quant / Systematic

Location: Bend, OR

CIK: 0001440771 · Show all filings

Period: Q1 2025 (← Previous) (Next →)

Filing Date: May 14, 2025

Total Value: $103M (100.0% shares, 0.0% debt)

Holdings (66)

EOLS EVOLUS INC 13.3%
Value $13.65M Shares 1,134,574 Share Price $12.03 * Est. Cost/Share $8.66 Unrealized @ Report Date +51.1%
ANIP ANI PHARMACEUTICALS INC 13.3%
Value $13.65M Shares 48,000 Share Price $284.35 * Est. Cost/Share $58.74 Unrealized @ Report Date +1.7%
— OPTINOSE INC 7.0%
Value $7.232M Shares 788,647 Share Price $9.17 Est. Cost/Share $7.31 Unrealized @ Report Date —
ZVRA ZEVRA THERAPEUTICS INC 4.7%
Value $4.869M Shares 650,000 Share Price $7.49 * Est. Cost/Share $6.87 Unrealized @ Report Date +15.6%
VSTM VERASTEM INC 3.6%
Value $3.696M Shares 613,000 Share Price $6.03 Est. Cost/Share $2.71 Unrealized @ Report Date +125.2%
URGN UROGEN PHARMA LTD 3.6%
Value $3.687M Shares 333,400 Share Price $11.06 * Est. Cost/Share $14.35 Unrealized @ Report Date -25.7%
SRZN SURROZEN INC 3.2%
Value $3.332M Shares 285,782 Share Price $11.66 Est. Cost/Share $10.80 Unrealized @ Report Date +7.7%
ANIK ANIKA THERAPEUTICS INC 3.2%
Value $3.261M Shares 206,639 Share Price $15.78 * Est. Cost/Share $24.21 Unrealized @ Report Date -31.3%
ENTA ENANTA PHARMACEUTICALS INC 3.2%
Value $3.261M Shares 590,742 Share Price $5.52 * Est. Cost/Share $8.09 Unrealized @ Report Date -23.7%
ESTA ESTABLISHMENT LABS HLDGS INC 3.0%
Value $3.04M Shares 74,500 Share Price $40.81 * Est. Cost/Share $43.49 Unrealized @ Report Date -14.3%
AQST AQUESTIVE THERAPEUTICS INC 3.0%
Value $3.04M Shares 200,000 Share Price $15.20 * Est. Cost/Share $4.29 Unrealized @ Report Date -29.5%
— INDIVIOR PLC 2.8%
Value $2.897M Shares 304,000 Share Price $9.53 Est. Cost/Share $10.06 Unrealized @ Report Date —
DAWN DAY ONE BIOPHARMACEUTICALS I 2.7%
Value $2.766M Shares 348,820 Share Price $7.93 * Est. Cost/Share $13.10 Unrealized @ Report Date -17.8%
ACRS ACLARIS THERAPEUTICS INC 2.7%
Value $2.766M Shares 527,842 Share Price $5.24 * Est. Cost/Share $1.19 Unrealized @ Report Date +79.8%
XOMA XOMA ROYALTY CORPORATION 2.5%
Value $2.587M Shares 129,813 Share Price $19.93 * Est. Cost/Share $19.88 Unrealized @ Report Date +21.1%
TELA TELA BIO INC 2.4%
Value $2.507M Shares 2,055,225 Share Price $1.22 * Est. Cost/Share $4.41 Unrealized @ Report Date -44.3%
GLPG GALAPAGOS NV 2.3%
Value $2.36M Shares 93,968 Share Price $25.12 Est. Cost/Share $34.61 Unrealized @ Report Date —
IKT INHIBIKASE THERAPEUTICS INC 1.9%
Value $2.004M Shares 914,973 Share Price $2.19 * Est. Cost/Share $2.49 Unrealized @ Report Date +0.7%
HRTX HERON THERAPEUTICS INC 1.7%
Value $1.751M Shares 796,100 Share Price $2.20 * Est. Cost/Share $1.66 Unrealized @ Report Date +17.0%
EDSA EDESA BIOTECH INC 1.6%
Value $1.677M Shares 687,500 Share Price $2.44 * Est. Cost/Share $2.16 Unrealized @ Report Date 0.0%
MYO MYOMO INC 1.3%
Value $1.331M Shares 276,707 Share Price $4.81 * Est. Cost/Share $4.60 Unrealized @ Report Date +23.9%
KROS KEROS THERAPEUTICS INC 1.0%
Value $1.019M Shares 100,000 Share Price $10.19 * Est. Cost/Share $11.61 Unrealized @ Report Date 0.0%
VIR VIR BIOTECHNOLOGY INC 0.9%
Value $937K Shares 144,628 Share Price $6.48 * Est. Cost/Share $7.89 Unrealized @ Report Date +12.7%
— SCPHARMACEUTICALS INC 0.9%
Value $914K Shares 347,687 Share Price $2.63 Est. Cost/Share $4.81 Unrealized @ Report Date —
INO INOVIO PHARMACEUTICALS INC 0.8%
Value $845K Shares 518,331 Share Price $1.63 * Est. Cost/Share $4.43 Unrealized @ Report Date -54.7%
PROF PROFOUND MEDICAL CORP 0.8%
Value $814K Shares 139,942 Share Price $5.82 * Est. Cost/Share $7.68 Unrealized @ Report Date -10.1%
GERN GERON CORP 0.8%
Value $795K Shares 500,000 Share Price $1.59 * Est. Cost/Share $2.44 Unrealized @ Report Date 0.0%
AYTU AYTU BIOPHARMA INC 0.8%
Value $795K Shares 463,721 Share Price $1.71 * Est. Cost/Share $1.93 Unrealized @ Report Date -24.7%
— THIRD HARMONIC BIO INC 0.7%
Value $738K Shares 212,783 Share Price $3.47 Est. Cost/Share $3.47 Unrealized @ Report Date —
PMVP PMV PHARMACEUTICALS INC 0.7%
Value $687K Shares 630,183 Share Price $1.09 * Est. Cost/Share $1.55 Unrealized @ Report Date -12.4%
GRCE GRACE THERAPEUTICS INC 0.6%
Value $666K Shares 294,550 Share Price $2.26 * Est. Cost/Share $3.15 Unrealized @ Report Date 0.0%
— ITEOS THERAPEUTICS INC 0.6%
Value $657K Shares 110,000 Share Price $5.97 Est. Cost/Share $8.37 Unrealized @ Report Date —
CALC CALCIMEDICA INC 0.6%
Value $615K Shares 367,371 Share Price $1.67 * Est. Cost/Share $3.50 Unrealized @ Report Date -28.9%
COLL COLLEGIUM PHARMACEUTICAL INC 0.6%
Value $615K Shares 20,607 Share Price $29.85 * Est. Cost/Share $30.56 Unrealized @ Report Date 0.0%
KPRX KIORA PHARMACEUTICALS INC 0.6%
Value $604K Shares 200,647 Share Price $3.01 * Est. Cost/Share $3.90 Unrealized @ Report Date -11.0%
— Y-MABS THERAPEUTICS INC 0.6%
Value $581K Shares 131,160 Share Price $4.43 Est. Cost/Share $4.43 Unrealized @ Report Date —
XERS XERIS BIOPHARMA HOLDINGS INC 0.5%
Value $561K Shares 102,265 Share Price $5.49 * Est. Cost/Share $3.22 Unrealized @ Report Date +25.5%
CHRS COHERUS BIOSCIENCES INC 0.5%
Value $501K Shares 620,588 Share Price $0.81 * Est. Cost/Share $1.14 Unrealized @ Report Date +1.0%
KZR KEZAR LIFE SCIENCES INC 0.5%
Value $488K Shares 100,000 Share Price $4.88 * Est. Cost/Share $7.45 Unrealized @ Report Date -18.5%
— ACELYRIN INC 0.4%
Value $414K Shares 167,580 Share Price $2.47 Est. Cost/Share $3.00 Unrealized @ Report Date —
NBP I MAB 0.4%
Value $398K Shares 483,647 Share Price $0.82 Est. Cost/Share $0.82 Unrealized @ Report Date —
SEPN SEPTERNA INC 0.4%
Value $394K Shares 68,084 Share Price $5.79 * Est. Cost/Share $11.42 Unrealized @ Report Date 0.0%
— HILLEVAX INC 0.3%
Value $346K Shares 238,950 Share Price $1.45 Est. Cost/Share $1.79 Unrealized @ Report Date —
XGN EXAGEN INC 0.3%
Value $344K Shares 95,747 Share Price $3.59 * Est. Cost/Share $6.84 Unrealized @ Report Date -44.8%
RNXT RENOVORX INC 0.3%
Value $275K Shares 278,188 Share Price $0.99 * Est. Cost/Share $1.16 Unrealized @ Report Date 0.0%
KALV KALVISTA PHARMACEUTICALS INC 0.2%
Value $249K Shares 21,550 Share Price $11.54 * Est. Cost/Share $10.21 Unrealized @ Report Date 0.0%
— CARGO THERAPEUTICS INC 0.2%
Value $204K Shares 50,000 Share Price $4.07 Est. Cost/Share $4.07 Unrealized @ Report Date —
— ADICET BIO INC 0.2%
Value $204K Shares 508,266 Share Price $0.40 Est. Cost/Share $1.41 Unrealized @ Report Date —
MIST MILESTONE PHARMACEUTICALS IN 0.2%
Value $200K Shares 250,000 Share Price $0.80 * Est. Cost/Share $1.62 Unrealized @ Report Date +22.4%
BIOA BIOAGE LABS INC 0.2%
Value $188K Shares 50,000 Share Price $3.76 * Est. Cost/Share $4.62 Unrealized @ Report Date 0.0%
ACAD ACADIA PHARMACEUTICALS INC 0.2%
Value $186K Shares 93,393 Share Price $1.99 * Est. Cost/Share $16.61 Unrealized @ Report Date +9.3%
CRBP CORBUS PHARMACEUTICALS HLDGS 0.2%
Value $186K Shares 35,000 Share Price $5.31 * Est. Cost/Share $8.83 Unrealized @ Report Date 0.0%
VNDA VANDA PHARMACEUTICALS INC 0.2%
Value $161K Shares 35,148 Share Price $4.59 Est. Cost/Share $4.76 Unrealized @ Report Date -2.1%
PYPD POLYPID LTD 0.1%
Value $149K Shares 54,975 Share Price $2.71 * Est. Cost/Share $3.59 Unrealized @ Report Date -16.9%
ELAN ELANCO ANIMAL HEALTH INC 0.1%
Value $105K Shares 10,000 Share Price $10.50 * Est. Cost/Share $11.31 Unrealized @ Report Date 0.0%
— AMARIN CORP PLC 0.1%
Value $105K Shares 651,614 Share Price $0.16 Est. Cost/Share $0.22 Unrealized @ Report Date —
ZNTL ZENTALIS PHARMACEUTICALS LLC 0.1%
Value $95,400 Shares 60,000 Share Price $1.59 * Est. Cost/Share $2.16 Unrealized @ Report Date 0.0%
WHWK WHITEHAWK THERAPEUTICS INC 0.1%
Value $83,122 Shares 46,698 Share Price $1.78 * Est. Cost/Share $2.61 Unrealized @ Report Date 0.0%
SVRA SAVARA INC 0.1%
Value $80,549 Shares 29,079 Share Price $2.77 Est. Cost/Share $2.76 Unrealized @ Report Date 0.0%
IOVA IOVANCE BIOTHERAPEUTICS INC 0.1%
Value $66,600 Shares 20,000 Share Price $3.33 * Est. Cost/Share $5.16 Unrealized @ Report Date 0.0%
— THERATECHNOLOGIES INC 0.0%
Value $36,155 Shares 25,825 Share Price $1.40 Est. Cost/Share $1.40 Unrealized @ Report Date —
EBS EMERGENT BIOSOLUTIONS INC 0.0%
Value $24,300 Shares 5,000 Share Price $4.86 * Est. Cost/Share $8.28 Unrealized @ Report Date 0.0%
ADMA ADMA BIOLOGICS INC 0.0%
Value $24,300 Shares 810,000 Share Price $0.03 * Est. Cost/Share $2.26 Unrealized @ Report Date +663.9%
NKTX NKARTA INC 0.0%
Value $18,400 Shares 10,000 Share Price $1.84 * Est. Cost/Share $2.05 Unrealized @ Report Date 0.0%
APRE APREA THERAPEUTICS INC 0.0%
Value $14,400 Shares 102,242 Share Price $0.14 * Est. Cost/Share $5.01 Unrealized @ Report Date -37.5%
ESPR ESPERION THERAPEUTICS INC NE 0.0%
Value $14,400 Shares 10,000 Share Price $1.44 * Est. Cost/Share $1.84 Unrealized @ Report Date 0.0%