Stonepine Capital Management, LLC Quant / Systematic

Location: Bend, OR

CIK: 0001440771 · Show all filings

Period: Q3 2025 (← Previous) (Next →)

Filing Date: Nov 13, 2025

Total Value: $123M (100.0% shares, 0.0% debt)

Holdings (58)

VSTM VERASTEM INC 19.2%
Value $23.58M Shares 2,670,032 Share Price $8.83 * Est. Cost/Share $6.03 Unrealized @ Report Date +23.5%
ADMA ADMA BIOLOGICS INC 8.8%
Value $10.83M Shares 739,000 Share Price $14.66 * Est. Cost/Share $2.26 Unrealized @ Report Date +657.1%
EOLS EVOLUS INC 7.7%
Value $9.433M Shares 1,536,391 Share Price $6.14 * Est. Cost/Share $8.31 Unrealized @ Report Date -6.2%
ZVRA ZEVRA THERAPEUTICS INC 6.3%
Value $7.703M Shares 810,000 Share Price $9.51 * Est. Cost/Share $7.20 Unrealized @ Report Date +39.3%
NKTR NEKTAR THERAPEUTICS 3.9%
Value $4.837M Shares 85,000 Share Price $56.90 * Est. Cost/Share $20.19 Unrealized @ Report Date +64.0%
DAWN DAY ONE BIOPHARMACEUTICALS I 3.7%
Value $4.564M Shares 647,382 Share Price $7.05 * Est. Cost/Share $10.23 Unrealized @ Report Date -32.7%
XOMA XOMA ROYALTY CORPORATION 3.6%
Value $4.45M Shares 115,459 Share Price $38.54 * Est. Cost/Share $20.48 Unrealized @ Report Date +51.7%
ACAD ACADIA PHARMACEUTICALS INC 3.0%
Value $3.725M Shares 174,544 Share Price $21.34 * Est. Cost/Share $17.77 Unrealized @ Report Date +33.1%
ENTA ENANTA PHARMACEUTICALS INC 3.0%
Value $3.651M Shares 305,000 Share Price $11.97 * Est. Cost/Share $8.05 Unrealized @ Report Date -0.7%
XFOR X4 PHARMACEUTICALS INC 2.9%
Value $3.613M Shares 1,056,338 Share Price $3.42 * Est. Cost/Share $2.58 Unrealized @ Report Date 0.0%
OABI OMNIAB INC 2.8%
Value $3.429M Shares 2,142,857 Share Price $1.60 * Est. Cost/Share $1.83 Unrealized @ Report Date 0.0%
SRZN SURROZEN INC 2.6%
Value $3.223M Shares 250,146 Share Price $12.88 * Est. Cost/Share $10.69 Unrealized @ Report Date -1.9%
TELA TELA BIO INC 2.6%
Value $3.212M Shares 2,155,519 Share Price $1.49 * Est. Cost/Share $4.29 Unrealized @ Report Date -58.9%
— INDIVIOR PLC 2.0%
Value $2.411M Shares 100,000 Share Price $24.11 Est. Cost/Share $10.67 Unrealized @ Report Date —
ABEO ABEONA THERAPEUTICS INC 1.9%
Value $2.381M Shares 450,970 Share Price $5.28 * Est. Cost/Share $6.28 Unrealized @ Report Date +1.0%
GERN GERON CORP 1.8%
Value $2.192M Shares 1,600,000 Share Price $1.37 Est. Cost/Share $1.70 Unrealized @ Report Date -21.8%
PMVP PMV PHARMACEUTICALS INC 1.6%
Value $1.918M Shares 1,370,139 Share Price $1.40 Est. Cost/Share $1.40 Unrealized @ Report Date -0.9%
EDSA EDESA BIOTECH INC 1.4%
Value $1.698M Shares 687,500 Share Price $2.47 * Est. Cost/Share $2.31 Unrealized @ Report Date 0.0%
AYTU AYTU BIOPHARMA INC 1.4%
Value $1.677M Shares 891,855 Share Price $1.88 * Est. Cost/Share $1.82 Unrealized @ Report Date +27.1%
SLNO SOLENO THERAPEUTICS INC 1.3%
Value $1.622M Shares 24,000 Share Price $67.60 * Est. Cost/Share $74.14 Unrealized @ Report Date 0.0%
KZR KEZAR LIFE SCIENCES INC 1.2%
Value $1.494M Shares 383,182 Share Price $3.90 * Est. Cost/Share $5.01 Unrealized @ Report Date -18.1%
ALMS ALUMIS INC 1.0%
Value $1.197M Shares 300,000 Share Price $3.99 * Est. Cost/Share $4.72 Unrealized @ Report Date -12.8%
IKT INHIBIKASE THERAPEUTICS INC 1.0%
Value $1.191M Shares 735,019 Share Price $1.62 * Est. Cost/Share $2.49 Unrealized @ Report Date -30.6%
BIOA BIOAGE LABS INC 0.9%
Value $1.109M Shares 188,571 Share Price $5.88 * Est. Cost/Share $4.32 Unrealized @ Report Date +8.5%
ARDX ARDELYX INC 0.9%
Value $1.102M Shares 200,000 Share Price $5.51 Est. Cost/Share $4.13 Unrealized @ Report Date +31.7%
LUNG PULMONX CORP 0.9%
Value $1.085M Shares 670,000 Share Price $1.62 * Est. Cost/Share $2.50 Unrealized @ Report Date -16.2%
— DYNAVAX TECHNOLOGIES CORP 0.9%
Value $1.073M Shares 108,094 Share Price $9.93 Est. Cost/Share $9.93 Unrealized @ Report Date —
HRTX HERON THERAPEUTICS INC 0.9%
Value $1.071M Shares 850,100 Share Price $1.26 * Est. Cost/Share $1.64 Unrealized @ Report Date -3.5%
VNDA VANDA PHARMACEUTICALS INC 0.8%
Value $973K Shares 195,000 Share Price $4.99 * Est. Cost/Share $4.43 Unrealized @ Report Date +4.6%
VIR VIR BIOTECHNOLOGY INC 0.7%
Value $914K Shares 160,000 Share Price $5.71 * Est. Cost/Share $7.37 Unrealized @ Report Date -30.6%
MNKD MANNKIND CORP 0.7%
Value $846K Shares 157,569 Share Price $5.37 * Est. Cost/Share $4.39 Unrealized @ Report Date 0.0%
MXCT MAXCYTE INC 0.6%
Value $725K Shares 459,018 Share Price $1.58 * Est. Cost/Share $1.74 Unrealized @ Report Date 0.0%
ANTX AN2 THERAPEUTICS INC 0.6%
Value $716K Shares 563,913 Share Price $1.27 * Est. Cost/Share $1.19 Unrealized @ Report Date -4.0%
ZNTL ZENTALIS PHARMACEUTICALS INC 0.6%
Value $685K Shares 453,800 Share Price $1.51 Est. Cost/Share $1.57 Unrealized @ Report Date -4.3%
ANGO ANGIODYNAMICS INC 0.5%
Value $670K Shares 60,000 Share Price $11.17 * Est. Cost/Share $9.79 Unrealized @ Report Date -1.4%
GRCE GRACE THERAPEUTICS INC 0.5%
Value $628K Shares 211,010 Share Price $2.98 * Est. Cost/Share $3.15 Unrealized @ Report Date -0.5%
RARE ULTRAGENYX PHARMACEUTICAL IN 0.5%
Value $602K Shares 20,000 Share Price $30.08 Est. Cost/Share $29.99 Unrealized @ Report Date 0.0%
SNDX SYNDAX PHARMACEUTICALS INC 0.5%
Value $572K Shares 37,200 Share Price $15.38 * Est. Cost/Share $11.01 Unrealized @ Report Date +18.9%
AQST AQUESTIVE THERAPEUTICS INC 0.5%
Value $562K Shares 100,600 Share Price $5.59 * Est. Cost/Share $4.32 Unrealized @ Report Date 0.0%
GOSS GOSSAMER BIO INC 0.4%
Value $539K Shares 204,770 Share Price $2.63 * Est. Cost/Share $2.20 Unrealized @ Report Date 0.0%
BOLD BOUNDLESS BIO INC 0.4%
Value $509K Shares 413,453 Share Price $1.23 * Est. Cost/Share $1.20 Unrealized @ Report Date -3.7%
HCAT HEALTH CATALYST INC 0.4%
Value $443K Shares 155,551 Share Price $2.85 * Est. Cost/Share $3.75 Unrealized @ Report Date -8.7%
ESTA ESTABLISHMENT LABS HLDGS INC 0.4%
Value $434K Shares 10,585 Share Price $40.99 Est. Cost/Share $42.59 Unrealized @ Report Date -4.1%
PLRX PLIANT THERAPEUTICS INC 0.3%
Value $428K Shares 289,237 Share Price $1.48 Est. Cost/Share $1.53 Unrealized @ Report Date 0.0%
CTMX CYTOMX THERAPEUTICS INC 0.3%
Value $399K Shares 125,000 Share Price $3.19 * Est. Cost/Share $2.25 Unrealized @ Report Date 0.0%
KPRX KIORA PHARMACEUTICALS INC 0.3%
Value $391K Shares 140,598 Share Price $2.78 Est. Cost/Share $3.90 Unrealized @ Report Date -29.6%
RZLT REZOLUTE INC 0.3%
Value $376K Shares 40,000 Share Price $9.40 * Est. Cost/Share $3.71 Unrealized @ Report Date +79.3%
ACRS ACLARIS THERAPEUTICS INC 0.3%
Value $367K Shares 192,900 Share Price $1.90 * Est. Cost/Share $1.19 Unrealized @ Report Date +47.0%
INAB IN8BIO INC 0.3%
Value $346K Shares 159,421 Share Price $2.17 Est. Cost/Share $3.17 Unrealized @ Report Date -30.5%
HSDT HELIUS MED TECHNOLOGIES INC 0.2%
Value $298K Shares 20,000 Share Price $14.89 * Est. Cost/Share $9.16 Unrealized @ Report Date 0.0%
CDXS CODEXIS INC 0.2%
Value $215K Shares 88,264 Share Price $2.44 * Est. Cost/Share $2.73 Unrealized @ Report Date 0.0%
SVRA SAVARA INC 0.2%
Value $214K Shares 60,000 Share Price $3.57 * Est. Cost/Share $2.73 Unrealized @ Report Date +8.2%
ABVX ABIVAX SA 0.2%
Value $212K Shares 2,500 Share Price $84.90 Est. Cost/Share $84.90 Unrealized @ Report Date —
— PROCESSA PHARMACEUTICALS INC 0.2%
Value $198K Shares 1,030,200 Share Price $0.19 Est. Cost/Share $0.19 Unrealized @ Report Date —
LRMR LARIMAR THERAPEUTICS INC 0.1%
Value $80,750 Shares 25,000 Share Price $3.23 * Est. Cost/Share $3.75 Unrealized @ Report Date 0.0%
CMMB CHEMOMAB THERAPEUTICS LTD 0.1%
Value $78,900 Shares 30,000 Share Price $2.63 Est. Cost/Share $2.63 Unrealized @ Report Date —
WHWK WHITEHAWK THERAPEUTICS INC 0.1%
Value $66,981 Shares 35,253 Share Price $1.90 * Est. Cost/Share $1.84 Unrealized @ Report Date 0.0%
JSPR JASPER THERAPEUTICS INC 0.0%
Value $48,076 Shares 20,200 Share Price $2.38 * Est. Cost/Share $3.03 Unrealized @ Report Date 0.0%