Stonepine Capital Management, LLC Quant / Systematic

Location: Bend, OR

CIK: 0001440771 · Show all filings

Period: Q2 2025 (← Previous) (Next →)

Filing Date: Aug 13, 2025

Total Value: $102M (100.0% shares, 0.0% debt)

Holdings (59)

ADMA ADMA BIOLOGICS INC 13.4%
Value $13.66M Shares 750,000 Share Price $18.21 * Est. Cost/Share $2.26 Unrealized @ Report Date +800.7%
EOLS EVOLUS INC 8.3%
Value $8.441M Shares 916,500 Share Price $9.21 * Est. Cost/Share $8.66 Unrealized @ Report Date +18.2%
ZVRA ZEVRA THERAPEUTICS INC 6.7%
Value $6.833M Shares 775,620 Share Price $8.81 * Est. Cost/Share $7.07 Unrealized @ Report Date +14.7%
VSTM VERASTEM INC 5.5%
Value $5.646M Shares 1,360,386 Share Price $4.15 * Est. Cost/Share $4.66 Unrealized @ Report Date +34.3%
— INDIVIOR PLC 5.1%
Value $5.159M Shares 350,000 Share Price $14.74 Est. Cost/Share $10.67 Unrealized @ Report Date —
ACAD ACADIA PHARMACEUTICALS INC 4.8%
Value $4.853M Shares 225,000 Share Price $21.57 * Est. Cost/Share $17.77 Unrealized @ Report Date +4.6%
ENTA ENANTA PHARMACEUTICALS INC 4.5%
Value $4.567M Shares 604,066 Share Price $7.56 * Est. Cost/Share $8.05 Unrealized @ Report Date -25.3%
TELA TELA BIO INC 4.0%
Value $4.042M Shares 2,083,762 Share Price $1.94 * Est. Cost/Share $4.37 Unrealized @ Report Date -70.1%
XOMA XOMA ROYALTY CORPORATION 3.8%
Value $3.834M Shares 152,143 Share Price $25.20 * Est. Cost/Share $20.48 Unrealized @ Report Date +17.0%
— ITEOS THERAPEUTICS INC 3.0%
Value $3.091M Shares 310,033 Share Price $9.97 Est. Cost/Share $9.40 Unrealized @ Report Date —
DAWN DAY ONE BIOPHARMACEUTICALS I 2.9%
Value $2.925M Shares 450,000 Share Price $6.50 * Est. Cost/Share $11.70 Unrealized @ Report Date -41.2%
SRZN SURROZEN INC 2.7%
Value $2.736M Shares 306,029 Share Price $8.94 * Est. Cost/Share $10.69 Unrealized @ Report Date -14.5%
ANIP ANI PHARMACEUTICALS INC 2.5%
Value $2.518M Shares 38,597 Share Price $65.25 Est. Cost/Share $58.74 Unrealized @ Report Date +10.8%
ARDX ARDELYX INC 2.1%
Value $2.176M Shares 555,000 Share Price $3.92 * Est. Cost/Share $4.13 Unrealized @ Report Date 0.0%
ANIK ANIKA THERAPEUTICS INC 2.0%
Value $2.016M Shares 190,590 Share Price $10.58 * Est. Cost/Share $24.21 Unrealized @ Report Date -47.9%
AYTU AYTU BIOPHARMA INC 1.7%
Value $1.772M Shares 812,676 Share Price $2.18 * Est. Cost/Share $1.77 Unrealized @ Report Date -12.2%
IKT INHIBIKASE THERAPEUTICS INC 1.4%
Value $1.431M Shares 733,793 Share Price $1.95 Est. Cost/Share $2.49 Unrealized @ Report Date -21.5%
GERN GERON CORP 1.4%
Value $1.41M Shares 1,000,000 Share Price $1.41 Est. Cost/Share $1.93 Unrealized @ Report Date -26.4%
HRTX HERON THERAPEUTICS INC 1.3%
Value $1.361M Shares 657,380 Share Price $2.07 Est. Cost/Share $1.66 Unrealized @ Report Date +23.1%
NKTR NEKTAR THERAPEUTICS 1.3%
Value $1.297M Shares 50,200 Share Price $25.84 * Est. Cost/Share $11.24 Unrealized @ Report Date 0.0%
— Y-MABS THERAPEUTICS INC 1.3%
Value $1.287M Shares 285,300 Share Price $4.51 Est. Cost/Share $4.47 Unrealized @ Report Date —
COLL COLLEGIUM PHARMACEUTICAL INC 1.2%
Value $1.227M Shares 41,500 Share Price $29.57 * Est. Cost/Share $29.53 Unrealized @ Report Date -3.4%
VNDA VANDA PHARMACEUTICALS INC 1.2%
Value $1.18M Shares 250,000 Share Price $4.72 * Est. Cost/Share $4.43 Unrealized @ Report Date -1.2%
KALV KALVISTA PHARMACEUTICALS INC 1.1%
Value $1.131M Shares 100,000 Share Price $11.30 * Est. Cost/Share $11.79 Unrealized @ Report Date +3.7%
ALMS ALUMIS INC 1.0%
Value $1.049M Shares 349,615 Share Price $3.00 * Est. Cost/Share $4.72 Unrealized @ Report Date 0.0%
MYO MYOMO INC 1.0%
Value $988K Shares 457,419 Share Price $2.16 * Est. Cost/Share $4.22 Unrealized @ Report Date -14.0%
RZLT REZOLUTE INC 1.0%
Value $977K Shares 219,000 Share Price $4.46 * Est. Cost/Share $3.71 Unrealized @ Report Date 0.0%
XERS XERIS BIOPHARMA HOLDINGS INC 0.9%
Value $958K Shares 205,100 Share Price $4.67 Est. Cost/Share $3.90 Unrealized @ Report Date +17.4%
PMVP PMV PHARMACEUTICALS INC 0.9%
Value $897K Shares 845,968 Share Price $1.06 * Est. Cost/Share $1.40 Unrealized @ Report Date -30.2%
SNDX SYNDAX PHARMACEUTICALS INC 0.9%
Value $870K Shares 92,900 Share Price $9.37 * Est. Cost/Share $11.01 Unrealized @ Report Date 0.0%
GRCE GRACE THERAPEUTICS INC 0.9%
Value $869K Shares 292,500 Share Price $2.97 * Est. Cost/Share $3.15 Unrealized @ Report Date -15.5%
KZR KEZAR LIFE SCIENCES INC 0.8%
Value $778K Shares 169,859 Share Price $4.58 * Est. Cost/Share $6.15 Unrealized @ Report Date -30.3%
ANGO ANGIODYNAMICS INC 0.8%
Value $765K Shares 77,141 Share Price $9.92 Est. Cost/Share $9.79 Unrealized @ Report Date 0.0%
ACHV ACHIEVE LIFE SCIENCES INC 0.7%
Value $753K Shares 333,333 Share Price $2.26 * Est. Cost/Share $2.85 Unrealized @ Report Date 0.0%
ACRS ACLARIS THERAPEUTICS INC 0.7%
Value $698K Shares 491,300 Share Price $1.42 * Est. Cost/Share $1.19 Unrealized @ Report Date +14.1%
VIR VIR BIOTECHNOLOGY INC 0.6%
Value $655K Shares 130,000 Share Price $5.04 * Est. Cost/Share $7.89 Unrealized @ Report Date -32.0%
BIOA BIOAGE LABS INC 0.6%
Value $624K Shares 151,085 Share Price $4.13 * Est. Cost/Share $4.23 Unrealized @ Report Date -4.7%
LQDA LIQUIDIA CORPORATION 0.6%
Value $623K Shares 50,000 Share Price $12.46 * Est. Cost/Share $14.81 Unrealized @ Report Date 0.0%
ANTX AN2 THERAPEUTICS INC 0.6%
Value $577K Shares 544,494 Share Price $1.06 * Est. Cost/Share $1.19 Unrealized @ Report Date 0.0%
KPRX KIORA PHARMACEUTICALS INC 0.5%
Value $513K Shares 178,000 Share Price $2.88 * Est. Cost/Share $3.90 Unrealized @ Report Date -21.9%
SPRO SPERO THERAPEUTICS INC 0.4%
Value $455K Shares 156,888 Share Price $2.90 * Est. Cost/Share $1.44 Unrealized @ Report Date 0.0%
— HILLEVAX INC 0.4%
Value $450K Shares 226,009 Share Price $1.99 Est. Cost/Share $1.79 Unrealized @ Report Date —
— THERATECHNOLOGIES INC 0.4%
Value $446K Shares 189,051 Share Price $2.36 Est. Cost/Share $2.23 Unrealized @ Report Date —
VSTM VERASTEM INC 0.4%
Value $415K Shares 100,000 Share Price $4.15 * Est. Cost/Share $4.66 Unrealized @ Report Date +34.3%
LUNG PULMONX CORP 0.4%
Value $378K Shares 145,900 Share Price $2.59 * Est. Cost/Share $3.94 Unrealized @ Report Date 0.0%
HCAT HEALTH CATALYST INC 0.4%
Value $377K Shares 100,000 Share Price $3.77 * Est. Cost/Share $3.93 Unrealized @ Report Date 0.0%
ESTA ESTABLISHMENT LABS HLDGS INC 0.3%
Value $299K Shares 7,000 Share Price $42.71 * Est. Cost/Share $43.49 Unrealized @ Report Date -19.8%
— DYNAVAX TECHNOLOGIES CORP 0.3%
Value $298K Shares 30,000 Share Price $9.92 Est. Cost/Share $9.92 Unrealized @ Report Date —
ABEO ABEONA THERAPEUTICS INC 0.3%
Value $256K Shares 45,000 Share Price $5.68 Est. Cost/Share $5.69 Unrealized @ Report Date 0.0%
SVRA SAVARA INC 0.2%
Value $194K Shares 85,000 Share Price $2.28 * Est. Cost/Share $2.73 Unrealized @ Report Date -0.5%
INAB IN8BIO INC 0.2%
Value $172K Shares 82,430 Share Price $2.09 * Est. Cost/Share $4.07 Unrealized @ Report Date 0.0%
NUVB NUVATION BIO INC 0.2%
Value $166K Shares 85,300 Share Price $1.95 * Est. Cost/Share $2.08 Unrealized @ Report Date 0.0%
KURA KURA ONCOLOGY INC 0.1%
Value $144K Shares 25,000 Share Price $5.77 * Est. Cost/Share $6.13 Unrealized @ Report Date 0.0%
CLYM CLIMB BIO INC 0.1%
Value $144K Shares 116,147 Share Price $1.24 Est. Cost/Share $1.24 Unrealized @ Report Date 0.0%
CALC CALCIMEDICA INC 0.1%
Value $136K Shares 85,000 Share Price $1.60 * Est. Cost/Share $3.50 Unrealized @ Report Date -51.0%
GLUE MONTE ROSA THERAPEUTICS INC 0.1%
Value $135K Shares 30,000 Share Price $4.51 Est. Cost/Share $4.46 Unrealized @ Report Date 0.0%
ZNTL ZENTALIS PHARMACEUTICALS LLC 0.1%
Value $126K Shares 109,010 Share Price $1.16 * Est. Cost/Share $1.78 Unrealized @ Report Date -25.9%
BOLD BOUNDLESS BIO INC 0.1%
Value $107K Shares 106,175 Share Price $1.01 * Est. Cost/Share $1.33 Unrealized @ Report Date 0.0%
CHRS COHERUS BIOSCIENCES INC 0.0%
Value $45,853 Shares 62,700 Share Price $0.73 * Est. Cost/Share $1.14 Unrealized @ Report Date -24.2%