Location: New York, NY
CIK: 0001633313 · Show all filings
Period: Q3 2021 (← Previous) (Next →)
Filing Date: Nov 15, 2021
Total Value: $6.366B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| — | HORIZON THERAPEUTICS PLC | 9,000,000 | $986M | 15.5% | $46.60 | — | Common | G46188101 |
| — | MIRATI THERAPEUTICS INC | 5,000,000 | $885M | 13.9% | $50.41 | — | Common | 60468T105 |
| — | ACCELERON PHARMA INC | 4,000,000 | $688M | 10.8% | $130.91 | — | Common | 00434H108 |
| UTHR | UNITED THERAPEUTICS CORP | 3,000,000 | $554M | 8.7% | $133.00 | +48.1% | Common | 91307C102 |
| ASND | ASCENDIS PHARMA | 1,980,000 | $316M | 5.0% | $132.67 | — | Sponsored ADR | 04351P101 |
| ARGX | ARGENX SE | 946,500 | $286M | 4.5% | $77.97 | — | Sponsored ADR | 04016X101 |
| SRPT | SAREPTA THERAPEUTICS INC | 2,500,000 | $231M | 3.6% | $102.59 | -24.9% | Common | 803607100 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 8,500,000 | $210M | 3.3% | $16.37 | +43.9% | Common | 462260100 |
| — | ARENA PHARMACEUTICALS INC | 3,425,000 | $204M | 3.2% | $72.64 | — | Common | 040047607 |
| FOLD | AMICUS THERAPEUTICS INC | 17,679,273 | $169M | 2.7% | $11.30 | -9.5% | Common | 03152W109 |
| APLS | APELLIS PHARMACEUTICALS INC | 5,000,000 | $165M | 2.6% | $54.40 | +3.3% | Common | 03753U106 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 850,000 | $160M | 2.5% | $146.46 | +28.1% | Common | 02043Q107 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 1,875,000 | $145M | 2.3% | $83.95 | -6.0% | Common | 09061G101 |
| VRTX | VERTEX PHARMACEUTICALS INC | 664,000 | $120M | 1.9% | $219.65 | -11.1% | Common | 92532F100 |
| — | IVERIC BIO INC | 7,100,000 | $115M | 1.8% | $6.17 | — | Common | 46583P102 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 1,425,000 | $114M | 1.8% | $124.06 | -30.4% | Common | 558868105 |
| — | TRILLIUM THERAPEUTICS INC | 5,700,000 | $100M | 1.6% | $5.91 | — | Common | 89620X506 |
| PMVP | PMV PHARMACEUTICALS INC | 2,925,000 | $87.17M | 1.4% | $35.29 | -9.5% | Common | 69353Y103 |
| KURA | KURA ONCOLOGY INC | 4,000,000 | $74.92M | 1.2% | $25.17 | -25.1% | Common | 50127T109 |
| — | MERSANA THERAPEUTICS INC | 6,800,000 | $64.12M | 1.0% | $23.19 | — | Common | 59045L106 |
| GLUE | MONTE ROSA THERAPEUTICS INC | 3,311,434 | $61M | 1.0% | $20.37 | +40.7% | Common | 61225M102 |
| XENE | XENON PHARMACEUTICALS INC | 3,650,000 | $55.77M | 0.9% | $11.32 | +53.5% | Common | 98420N105 |
| WHWK | AADI BIOSCIENCES INC | 1,829,402 | $53.73M | 0.8% | $30.48 | 0.0% | Common | 00032Q104 |
| MNKD | MANNKIND CORP | 8,800,000 | $38.28M | 0.6% | $3.55 | +26.8% | Common | 56400P706 |
| — | CYMABAY THERAPEUTICS INC | 10,300,000 | $37.59M | 0.6% | $6.26 | — | Common | 23257D103 |
| — | MARINUS PHARMACEUTICALS INC | 3,235,000 | $36.81M | 0.6% | $12.20 | — | Common | 56854Q200 |
| ACAD | ACADIA PHARMACEUTICALS INC | 2,200,000 | $36.54M | 0.6% | $48.41 | -60.2% | Common | 004225108 |
| — | DECIPHERA PHARMACEUTICALS INC | 1,068,000 | $36.29M | 0.6% | $44.83 | — | Common | 24344T101 |
| — | AMARIN CORP PLC | 6,000,000 | $30.6M | 0.5% | $8.22 | — | Sponsored ADR | 023111206 |
| — | PRAXIS PRECISION MEDICINES INC | 1,600,000 | $29.58M | 0.5% | $43.99 | — | Common | 74006W108 |
| SNDX | SYNDAX PHARMACEUTICALS INC | 1,545,000 | $29.52M | 0.5% | $21.60 | -22.9% | Common | 87164F105 |
| RNAM | AVIDITY BIOSCIENCES INC | 1,150,000 | $28.32M | 0.4% | $25.10 | -13.4% | Common | 05370A108 |
| KYMR | KYMERA THERAPEUTICS INC | 455,750 | $26.77M | 0.4% | $57.98 | 0.0% | Common | 501575104 |
| — | DICE THERAPEUTICS INC | 800,000 | $26.2M | 0.4% | $32.75 | — | Common | 23345J104 |
| BIIB | BIOGEN INC | 84,000 | $23.77M | 0.4% | $327.75 | 0.0% | Common | 09062X103 |
| — | AVADEL PHARMACEUTICALS PLC | 2,275,000 | $22.3M | 0.4% | $7.90 | — | Sponsored ADR | 05337M104 |
| NUVL | NUVALENT INC | 1,257,671 | $22.29M | 0.4% | $29.01 | 0.0% | Common | 670703107 |
| DSGN | DESIGN THERAPEUTICS INC | 1,468,318 | $21.57M | 0.3% | $31.14 | -46.6% | Common | 25056L103 |
| TNGX | TANGO THERAPEUTICS INC | 1,550,000 | $20.04M | 0.3% | $11.99 | 0.0% | Common | 87583X109 |
| FENC | FENNEC PHARMACEUTICALS INC | 1,670,000 | $15.73M | 0.2% | $9.85 | -23.9% | Common | 31447P100 |
| — | ADVERUM BIOTECHNOLOGIES INC | 6,950,000 | $15.08M | 0.2% | $11.14 | — | Common | 00773U108 |
| — | MERUS N V | 450,000 | $9.9M | 0.2% | $20.89 | — | Common | N5749R100 |
| GNCAQ | GENOCEA BIOSCIENCES INC | 5,084,184 | $9.762M | 0.2% | $2.62 | -25.0% | Common | 372427401 |
| SRPT | SAREPTA THERAPEUTICS INC | 200,000 | $2.194M | 0.0% | $102.59 | -24.9% | Call | 803607100 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 650,000 | $1.54M | 0.0% | $16.37 | +43.9% | Call | 462260100 |
| APLS | APELLIS PHARMACEUTICALS INC | 1,515,000 | $1.26M | 0.0% | $54.40 | +3.3% | Call | 03753U106 |
| — | ACCELERON PHARMA INC | 476,100 | $32,000 | 0.0% | $130.91 | — | Call | 00434H108 |