ACUTA CAPITAL PARTNERS, LLC Hedge Fund

Location: Redwood City, CA

CIK: 0001582844 · Show all filings

Period: Q4 2022 (← Previous) (Next →)

Filing Date: Feb 14, 2023

Total Value: $163M (100.0% shares, 0.0% debt)

Holdings (34)

WHWK AADI BIOSCIENCES INC 12.1%

Value $19.62M Shares 1,849,402 Est. Cost $27.48 Unrealized -52.5%

VRDN VIRIDIAN THERAPEUTICS INC 7.1%

Value $11.58M Shares 396,500 Est. Cost $17.88 Unrealized +28.8%

APLS APELLIS PHARMACEUTICALS INC 6.9%

Value $11.25M Shares 217,500 Est. Cost $38.98 Unrealized +36.1%

TERN TERNS PHARMACEUTICALS INC 6.9%

Value $11.2M Shares 1,100,000 Est. Cost $5.72 Unrealized +16.4%

UTHR UNITED THERAPEUTICS CORP DEL 5.6%

Value $9.177M Shares 33,000 Est. Cost $220.39 Unrealized +14.5%

SRPT SAREPTA TEHRAPEUTICS INC 5.4%

Value $8.747M Shares 67,500 Est. Cost $106.61 Unrealized +8.7%

SNDX SYNDAX PHARMACEUTICALS INC 5.1%

Value $8.261M Shares 324,614 Est. Cost $19.57 Unrealized +19.2%

— IVERIC BIO INC 4.7%

Value $7.718M Shares 360,500 Est. Cost $7.63 Unrealized —

VTYX VENTYX BIOSCIENCES INC 4.7%

Value $7.558M Shares 290,500 Est. Cost $21.58 Unrealized +37.3%

PCVX VAXCYTE INC 4.3%

Value $6.929M Shares 144,500 Est. Cost $31.07 Unrealized +26.3%

— CYMABAY THERAPEUTICS INC. COMMON STOCK 3.9%

Value $6.364M Shares 1,015,000 Est. Cost $6.27 Unrealized —

KURA KURA ONCOLOGY INC. COMMON STOCK 3.8%

Value $6.224M Shares 501,500 Est. Cost $15.03 Unrealized -3.3%

— MERSANA THERAPEUTICS INC 3.4%

Value $5.567M Shares 950,000 Est. Cost $5.86 Unrealized —

— BELLUS HEALTH INC 3.2%

Value $5.199M Shares 632,500 Est. Cost $8.20 Unrealized —

CLDX CELLDEX THERAPEUTICS INC 3.2%

Value $5.126M Shares 115,000 Est. Cost $7.56 Unrealized +372.3%

RCKT ROCKET PHARMACEUTICALS INC 3.1%

Value $5.088M Shares 260,000 Est. Cost $18.42 Unrealized 0.0%

BCAB BIOATLA INC 2.5%

Value $4.125M Shares 500,000 Est. Cost $6.55 Unrealized +26.7%

ACRS ACLARIS THERAPEUTICS 2.5%

Value $4.016M Shares 255,000 Est. Cost $16.22 Unrealized -0.8%

KROS KEROS THERAPEUTICS INC 2.4%

Value $3.842M Shares 80,000 Est. Cost $46.71 Unrealized 0.0%

GHRS GH RESEARCH PLC 1.5%

Value $2.364M Shares 243,250 Est. Cost $20.48 Unrealized -47.2%

ARGX ARGEN SE 1.2%

Value $1.932M Shares 5,100 Est. Cost $378.83 Unrealized —

ARWR ARROWHEAD PHARMACEUTICALS INC 1.0%

Value $1.664M Shares 41,029 Est. Cost $42.29 Unrealized -21.6%

FULC FULCRUM THERAPEUTICS INC 0.8%

Value $1.347M Shares 185,000 Est. Cost $11.30 Unrealized -42.3%

PMVP PMV PHARMACEUTICALS INC 0.8%

Value $1.344M Shares 154,471 Est. Cost $17.26 Unrealized -38.2%

EYPT EYEPOINT PHARMACEUTICALS INC 0.7%

Value $1.062M Shares 303,396 Est. Cost $11.19 Unrealized -60.6%

IOVA IOVANCE BIOTHERAPEUTICS INC 0.6%

Value $982K Shares 153,639 Est. Cost $19.89 Unrealized -60.8%

MLTX MOONLAKE IMMUNOTHERAPEUTICS 0.6%

Value $982K Shares 93,500 Est. Cost $8.89 Unrealized 0.0%

PYXS PYXIS ONCOLOGY INC 0.6%

Value $897K Shares 669,158 Est. Cost $5.29 Unrealized -71.6%

RZLT REZOLUTE INC 0.5%

Value $869K Shares 420,000 Est. Cost $3.32 Unrealized -43.7%

— HORIZON THERAPEUTICS PLC 0.4%

Value $683K Shares 6,000 Est. Cost $106.80 Unrealized —

PRTA PROTHENA CORPORATION PLC 0.3%

Value $560K Shares 9,300 Est. Cost $58.56 Unrealized 0.0%

— IMARA INC 0.1%

Value $182K Shares 44,503 Est. Cost $4.09 Unrealized —

— KINNATE BIOPHARMA INC 0.0%

Value $30,500 Shares 5,000 Est. Cost $12.00 Unrealized —

— NUVATION BIO INC 0.0%

Value $13,125 Shares 90,832 Est. Cost $0.28 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
WHWK	AADI BIOSCIENCES INC	1,849,402	$19.62M	12.1%	$27.48	-52.5%	COM	00032Q104
VRDN	VIRIDIAN THERAPEUTICS INC	396,500	$11.58M	7.1%	$17.88	+28.8%	COM	92790C104
APLS	APELLIS PHARMACEUTICALS INC	217,500	$11.25M	6.9%	$38.98	+36.1%	COM	03753U106
TERN	TERNS PHARMACEUTICALS INC	1,100,000	$11.2M	6.9%	$5.72	+16.4%	COM	880881107
UTHR	UNITED THERAPEUTICS CORP DEL	33,000	$9.177M	5.6%	$220.39	+14.5%	COM	91307C102
SRPT	SAREPTA TEHRAPEUTICS INC	67,500	$8.747M	5.4%	$106.61	+8.7%	COM	803607100
SNDX	SYNDAX PHARMACEUTICALS INC	324,614	$8.261M	5.1%	$19.57	+19.2%	COM	87164F105
—	IVERIC BIO INC	360,500	$7.718M	4.7%	$7.63	—	COM	46583P102
VTYX	VENTYX BIOSCIENCES INC	290,500	$7.558M	4.7%	$21.58	+37.3%	COM	92332V107
PCVX	VAXCYTE INC	144,500	$6.929M	4.3%	$31.07	+26.3%	COM	92243G108
—	CYMABAY THERAPEUTICS INC. COMMON STOCK	1,015,000	$6.364M	3.9%	$6.27	—	COM	23257D103
KURA	KURA ONCOLOGY INC. COMMON STOCK	501,500	$6.224M	3.8%	$15.03	-3.3%	COM	50127T109
—	MERSANA THERAPEUTICS INC	950,000	$5.567M	3.4%	$5.86	—	COM	59045L106
—	BELLUS HEALTH INC	632,500	$5.199M	3.2%	$8.20	—	COM NEW	07987C204
CLDX	CELLDEX THERAPEUTICS INC	115,000	$5.126M	3.2%	$7.56	+372.3%	COM NEW	15117B202
RCKT	ROCKET PHARMACEUTICALS INC	260,000	$5.088M	3.1%	$18.42	0.0%	COM	77313F106
BCAB	BIOATLA INC	500,000	$4.125M	2.5%	$6.55	+26.7%	COM	09077B104
ACRS	ACLARIS THERAPEUTICS	255,000	$4.016M	2.5%	$16.22	-0.8%	COM	00461U105
KROS	KEROS THERAPEUTICS INC	80,000	$3.842M	2.4%	$46.71	0.0%	COM	492327101
GHRS	GH RESEARCH PLC	243,250	$2.364M	1.5%	$20.48	-47.2%	ORDINARY SHARES	G3855L106
ARGX	ARGEN SE	5,100	$1.932M	1.2%	$378.83	—	SPONSORED ADR	04016X101
ARWR	ARROWHEAD PHARMACEUTICALS INC	41,029	$1.664M	1.0%	$42.29	-21.6%	COM	04280A100
FULC	FULCRUM THERAPEUTICS INC	185,000	$1.347M	0.8%	$11.30	-42.3%	COM	359616109
PMVP	PMV PHARMACEUTICALS INC	154,471	$1.344M	0.8%	$17.26	-38.2%	COM	69353Y103
EYPT	EYEPOINT PHARMACEUTICALS INC	303,396	$1.062M	0.7%	$11.19	-60.6%	COM NEW	30233G209
IOVA	IOVANCE BIOTHERAPEUTICS INC	153,639	$982K	0.6%	$19.89	-60.8%	COM	462260100
MLTX	MOONLAKE IMMUNOTHERAPEUTICS	93,500	$982K	0.6%	$8.89	0.0%	CLASS A ORD	61559X104
PYXS	PYXIS ONCOLOGY INC	669,158	$897K	0.6%	$5.29	-71.6%	COMMON STOCK	747324101
RZLT	REZOLUTE INC	420,000	$869K	0.5%	$3.32	-43.7%	COM NEW	76200L309
—	HORIZON THERAPEUTICS PLC	6,000	$683K	0.4%	$106.80	—	SHS	G46188101
PRTA	PROTHENA CORPORATION PLC	9,300	$560K	0.3%	$58.56	0.0%	SHS	G72800108
—	IMARA INC	44,503	$182K	0.1%	$4.09	—	COM	45249V107
—	KINNATE BIOPHARMA INC	5,000	$30,500	0.0%	$12.00	—	COM	49705R105
—	NUVATION BIO INC	90,832	$13,125	0.0%	$0.28	—	*W EXP 07/07/2027	67080N119