Location: New York, NY
CIK: 0001633313 · Show all filings
Period: Q4 2023 (← Previous) (Next →)
Filing Date: Feb 14, 2024
Total Value: $7.24B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| APLS | APELLIS PHARMACEUTICALS INC | 11,111,111 | $665M | 9.2% | $48.71 | +4.2% | Common | 03753U106 |
| UTHR | UNITED THERAPEUTICS CORP | 2,858,888 | $629M | 8.7% | $134.94 | +70.8% | Common | 91307C102 |
| ASND | ASCENDIS PHARMA | 3,755,555 | $473M | 6.5% | $120.31 | — | Sponsored ADR | 04351P101 |
| ARGX | ARGENX SE | 1,234,567 | $470M | 6.5% | $186.36 | — | Sponsored ADR | 04016X101 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 1,888,888 | $437M | 6.0% | $130.14 | +34.5% | Common | 558868105 |
| SRPT | SAREPTA THERAPEUTICS INC | 4,344,444 | $419M | 5.8% | $106.42 | -9.9% | Common | 803607100 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 4,300,000 | $415M | 5.7% | $86.02 | +2.8% | Common | 09061G101 |
| XBI | SPDR SERIES TRUST - S&P BIOTECH | 4,444,444 | $397M | 5.5% | $89.29 | — | ETF | 78464A870 |
| FOLD | AMICUS THERAPEUTICS INC | 27,400,000 | $389M | 5.4% | $10.47 | +8.5% | Common | 03152W109 |
| — | CEREVEL THERAPEUTICS HLDNG | 7,555,555 | $320M | 4.4% | $39.80 | — | Common | 15678U128 |
| KRYS | KRYSTAL BIOTECH INC | 2,565,555 | $318M | 4.4% | $77.73 | +42.7% | Common | 501147102 |
| — | MIRATI THERAPEUTICS INC | 4,886,840 | $287M | 4.0% | $52.11 | — | Common | 60468T105 |
| — | CYMABAY THERAPEUTICS INC | 11,111,111 | $262M | 3.6% | $7.53 | — | Common | 23257D103 |
| XENE | XENON PHARMACEUTICALS INC | 5,666,666 | $261M | 3.6% | $18.87 | +87.3% | Common | 98420N105 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 1,111,111 | $213M | 2.9% | $155.24 | +9.7% | Common | 02043Q107 |
| — | INTRA-CELLULAR THERAPIES INC | 2,255,555 | $162M | 2.2% | $71.62 | — | Common | 46116X101 |
| MLTX | MOONLAKE IMMUNOTHERAPEUTICS | 2,580,000 | $156M | 2.2% | $35.46 | +45.3% | CLASS A ORD | 61559X104 |
| KYMR | KYMERA THERAPEUTICS INC | 3,775,000 | $96.11M | 1.3% | $31.77 | -43.7% | Common | 501575104 |
| GPCR | STRUCTURE THERAPEUTICS INC | 2,333,333 | $95.11M | 1.3% | $44.90 | — | Sponsored ADR | 86366E106 |
| SNDX | SYNDAX PHARMACEUTICALS INC | 4,222,222 | $91.24M | 1.3% | $18.81 | -18.3% | Common | 87164F105 |
| BCRX | BIOCRYST PHARMACEUTICALS INC | 13,050,000 | $78.17M | 1.1% | $10.72 | -45.9% | Common | 09058V103 |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 6,700,000 | $54.47M | 0.8% | $16.40 | -68.1% | Common | 462260100 |
| ROIV | ROIVANT SCIENCES LTD | 4,651,162 | $52.23M | 0.7% | $8.94 | +9.0% | Common | G76279101 |
| KURA | KURA ONCOLOGY INC | 2,980,000 | $42.85M | 0.6% | $23.38 | -57.9% | Common | 50127T109 |
| SYRE | SPYRE THERAPEUTICS INC | 1,839,138 | $39.58M | 0.5% | $13.77 | +0.0% | Common | 00773J202 |
| — | KARUNA THERAPEUTICS INC | 125,000 | $39.56M | 0.5% | $316.51 | — | Common | 48576A100 |
| RCKT | ROCKET PHARMACEUTICALS INC | 1,260,900 | $37.79M | 0.5% | $18.18 | +21.4% | Common | 77313F106 |
| ARWR | ARROWHEAD PHARMACEUTICALS INC | 1,130,000 | $34.58M | 0.5% | $29.81 | -10.9% | Common | 04280A100 |
| — | MARINUS PHARMACEUTICALS INC | 3,150,000 | $34.24M | 0.5% | $12.20 | — | Common | 56854Q200 |
| MNKD | MANNKIND CORP | 9,000,000 | $32.76M | 0.5% | $3.56 | +7.4% | Common | 56400P706 |
| SLNO | SOLENO THERAPEUTICS INC | 785,000 | $31.6M | 0.4% | $28.45 | 0.0% | Common | 834203309 |
| — | VERRICA PHARMACEUTICALS INC | 3,999,999 | $29.28M | 0.4% | $6.66 | — | Common | 92511W108 |
| — | IMMUNOGEN INC | 875,000 | $25.94M | 0.4% | $29.65 | — | Common | 45253H101 |
| GLUE | MONTE ROSA THERAPEUTICS INC | 4,535,000 | $25.62M | 0.4% | $17.04 | -77.0% | Common | 61225M102 |
| — | MERUS N V | 888,888 | $24.44M | 0.3% | $25.54 | — | Common | N5749R100 |
| — | TOURMALINE BIO INC | 868,407 | $22.73M | 0.3% | $26.18 | — | Common | 89157D105 |
| RNAM | AVIDITY BIOSCIENCES INC | 2,510,000 | $22.72M | 0.3% | $21.47 | -68.9% | Common | 05370A108 |
| RARE | ULTRAGENYX PHARMACEUTICAL INC | 350,000 | $16.74M | 0.2% | $51.81 | -25.2% | Common | 90400D108 |
| FENC | FENNEC PHARMACEUTICALS INC | 1,200,000 | $13.46M | 0.2% | $9.85 | -15.9% | Common | 31447P100 |
| NUVL | NUVALENT INC | 178,921 | $13.17M | 0.2% | $28.81 | +114.8% | Common | 670703107 |
| TSHA | TAYSHA GENE THERAPIES INC | 4,355,555 | $7.709M | 0.1% | $1.88 | +6.0% | Common | 877619106 |
| WHWK | AADI BIOSCIENCES INC | 2,849,402 | $5.756M | 0.1% | $24.27 | -82.7% | Common | 00032Q104 |