Location: Boston, MA
CIK: 0001583977 · Show all filings
Period: Q4 2015 (← Previous) (Next →)
Filing Date: Feb 16, 2016
Total Value: $836M (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| ALKS | ALKERMES PLC | 700,000 | $55.57M | 6.6% | $56.67 | +23.6% | SHS | G01767105 |
| — | DYAX CORP | 1,400,000 | $52.67M | 6.3% | $11.07 | — | COM | 26746E103 |
| HRTX | HERON THERAPEUTICS INC | 1,685,719 | $45.01M | 5.4% | $15.53 | +72.2% | COM | 427746102 |
| EGRX | EAGLE PHARMACEUTICALS INC | 400,000 | $35.47M | 4.2% | $34.82 | +126.7% | COM | 269796108 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 603,900 | $34.16M | 4.1% | $15.30 | +232.3% | COM | 64125C109 |
| OMER | OMEROS CORP | 1,960,000 | $30.83M | 3.7% | $15.02 | -8.0% | COM | 682143102 |
| ARDX | ARDELYX INC | 1,481,075 | $26.84M | 3.2% | $17.63 | +5.6% | COM | 039697107 |
| — | PORTOLA PHARMACEUTICALS INC | 500,000 | $25.73M | 3.1% | $27.49 | — | COM | 737010108 |
| — | ALDER BIOPHARMACEUTICALS INC | 757,475 | $25.02M | 3.0% | $41.16 | — | COM | 014339105 |
| — | QUOTIENT LTD | 1,519,100 | $24.31M | 2.9% | $14.29 | — | SHS | G73268107 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 245,000 | $23.06M | 2.8% | $108.02 | -14.2% | COM | 02043Q107 |
| — | SAGE THERAPEUTICS INC | 315,000 | $18.36M | 2.2% | $46.13 | — | COM | 78667J108 |
| SRNE | SORRENTO THERAPEUTICS INC | 2,095,334 | $18.25M | 2.2% | $9.16 | -7.9% | COM NEW | 83587F202 |
| — | NEVRO CORP | 265,386 | $17.92M | 2.1% | $51.69 | — | COM | 64157F103 |
| ACRS | ACLARIS THERAPEUTICS INC | 647,944 | $17.46M | 2.1% | $19.34 | 0.0% | COM | 00461U105 |
| — | CHINA BIOLOGIC PRODUCTS INC | 111,500 | $15.88M | 1.9% | $66.66 | — | COM | 16938C106 |
| — | MIRATI THERAPEUTICS INC | 495,356 | $15.65M | 1.9% | $33.05 | — | COM | 60468T105 |
| MGNX | MACROGENICS INC | 500,000 | $15.48M | 1.9% | $30.38 | 0.0% | COM | 556099109 |
| — | TESARO INC | 291,250 | $15.24M | 1.8% | $38.73 | — | COM | 881569107 |
| CLLS | CELLECTIS SA | 469,145 | $14.56M | 1.7% | $31.12 | — | SPONSORED ADS | 15117K103 |
| — | DYNAVAX TECHNOLOGIES CORP | 575,000 | $13.89M | 1.7% | $23.57 | — | COM NEW | 268158201 |
| — | NOVAVAX INC | 1,600,000 | $13.42M | 1.6% | $6.35 | — | COM | 670002104 |
| CHRS | COHERUS BIOSCIENCES INC | 569,130 | $13.07M | 1.6% | $20.98 | +22.7% | COM | 19249H103 |
| — | NEKTAR THERAPEUTICS | 765,156 | $12.89M | 1.5% | $14.37 | — | COM | 640268108 |
| DXCM | DEXCOM INC | 153,000 | $12.53M | 1.5% | $7.91 | +162.9% | COM | 252131107 |
| COLL | COLLEGIUM PHARMACEUTICAL INC | 450,000 | $12.38M | 1.5% | $17.29 | +21.8% | COM | 19459J104 |
| RARE | ULTRAGENYX PHARMACEUTICAL INC | 109,500 | $12.28M | 1.5% | $50.99 | +96.1% | COM | 90400D108 |
| — | ROCKWELL MEDICAL INC | 1,105,000 | $11.31M | 1.4% | $9.23 | — | COM | 774374102 |
| — | VITAE PHARMACEUTICALS INC | 623,409 | $11.28M | 1.3% | $18.10 | — | COM | 92847N103 |
| BCRX | BIOCRYST PHARMACEUTICALS INC | 1,080,000 | $11.15M | 1.3% | $11.03 | -9.8% | COM | 09058V103 |
| — | MYOKARDIA INC | 753,388 | $11.04M | 1.3% | $14.66 | — | COM | 62857M105 |
| — | ACCELERON PHARMA INC | 200,000 | $9.752M | 1.2% | $32.04 | — | COM | 00434H108 |
| — | SERES THERAPEUTICS INC | 250,000 | $8.773M | 1.0% | $32.01 | — | COM | 81750R102 |
| — | LIPOCINE INC | 666,666 | $8.62M | 1.0% | $6.90 | — | COM | 53630X104 |
| — | ADVAXIS INC | 800,000 | $8.048M | 1.0% | $7.24 | — | COM NEW | 007624208 |
| CTMX | CYTOMX THERAPEUTICS INC | 371,023 | $7.743M | 0.9% | $15.82 | 0.0% | COM | 23284F105 |
| — | PFENEX INC | 624,900 | $7.736M | 0.9% | $16.77 | — | COM | 717071104 |
| — | AGENUS INC | 1,559,000 | $7.078M | 0.8% | $4.54 | — | COM NEW | 00847G705 |
| — | RECRO PHARMA INC | 780,000 | $7.02M | 0.8% | $7.16 | — | COM | 75629F109 |
| — | MINERVA NEUROSCIENCES INC | 1,145,043 | $6.95M | 0.8% | $5.16 | — | COM | 603380106 |
| — | FORWARD PHARMA A/S | 335,068 | $6.366M | 0.8% | $23.83 | — | SPONSORED ADR | 34986J105 |
| WVE | WAVE LIFE SCIENCES PTE LTD | 392,079 | $6.254M | 0.7% | $15.68 | 0.0% | SHS | Y95308105 |
| — | BELLICUM PHARMACEUTICALS INC | 300,000 | $6.081M | 0.7% | $20.27 | — | COM | 079481107 |
| — | DERMIRA INC | 170,000 | $5.884M | 0.7% | $18.11 | — | COM | 24983L104 |
| — | ACHILLION PHARMACEUTICALS IN | 500,000 | $5.395M | 0.6% | $10.79 | — | COM | 00448Q201 |
| — | INTEC PHARMA LTD | 800,000 | $4.288M | 0.5% | $5.60 | — | SHS | M53644106 |
| — | EPIZYME INC | 266,250 | $4.265M | 0.5% | $18.78 | — | COM | 29428V104 |
| — | KITE PHARMA INC | 68,800 | $4.239M | 0.5% | $46.23 | — | COM | 49803L109 |
| — | CELYAD SA | 75,000 | $4.094M | 0.5% | $52.03 | — | ADR | 151205200 |
| — | ATARA BIOTHERAPEUTICS INC | 150,000 | $3.962M | 0.5% | $38.55 | — | COM | 046513107 |
| — | LION BIOTECHNOLOGIES INC | 499,815 | $3.859M | 0.5% | $11.67 | — | COM | 53619R102 |
| — | IMMUNE DESIGN CORP | 189,000 | $3.795M | 0.5% | $18.77 | — | COM | 45252L103 |
| — | ZYNERBA PHARMACEUTICALS INC | 356,600 | $3.591M | 0.4% | $14.31 | — | COM | 98986X109 |
| — | CURIS INC | 1,162,400 | $3.383M | 0.4% | $2.28 | — | COM | 231269101 |
| — | EPIRUS BIOPHARMACEUTICALS IN | 896,600 | $2.77M | 0.3% | $8.68 | — | COM | 29428P107 |
| — | APTOSE BIOSCIENCES INC | 1,081,867 | $2.737M | 0.3% | $5.91 | — | COM NEW | 03835T200 |
| — | BLUEPRINT MEDICINES CORP | 100,000 | $2.634M | 0.3% | $26.49 | — | COM | 09627Y109 |
| RGNX | REGENXBIO INC | 156,741 | $2.602M | 0.3% | $25.52 | -22.2% | COM | 75901B107 |
| — | OVASCIENCE INC | 252,180 | $2.464M | 0.3% | $25.13 | — | COM | 69014Q101 |
| — | GENVEC INC | 1,176,235 | $2.164M | 0.3% | $2.65 | — | COM NEW | 37246C307 |
| — | TETRALOGIC PHARMACEUTICALS C | 5,000,000 | $2.078M | 0.2% | $0.60 | — | NOTE 8.000% 6/1 | 88165UAB5 |
| — | AQUINOX PHARMACEUTICALS INC | 150,000 | $1.872M | 0.2% | $12.15 | — | COM | 03842B101 |
| — | AGILE THERAPEUTICS INC | 182,053 | $1.777M | 0.2% | $8.82 | — | COM | 00847L100 |
| — | GLYCOMIMETICS INC | 283,555 | $1.622M | 0.2% | $16.33 | — | COM | 38000Q102 |
| FOLD | AMICUS THERAPEUTICS INC | 150,000 | $1.455M | 0.2% | $12.02 | -25.0% | COM | 03152W109 |
| — | AVEO PHARMACEUTICALS INC | 1,087,715 | $1.371M | 0.2% | $1.74 | — | COM | 053588109 |
| ASND | ASCENDIS PHARMA A/S | 61,500 | $1.127M | 0.1% | $17.35 | — | SPONSORED ADR | 04351P101 |
| — | CONTRAFECT CORP | 234,406 | $1.113M | 0.1% | $5.25 | — | COM | 212326102 |
| VCYT | VERACYTE INC | 137,990 | $994K | 0.1% | $7.94 | -15.2% | COM | 92337F107 |
| — | HTG MOLECULAR DIAGNOSTICS | 201,000 | $876K | 0.1% | $11.15 | — | COM | 40434H104 |
| PVCT | PROVECTUS BIOPHARMACEUTICALS | 2,200,000 | $858K | 0.1% | $0.82 | -41.9% | COM | 74373P108 |
| — | PRONAI THERAPEUTICS INC | 53,153 | $799K | 0.1% | $20.53 | — | COM | 74346L101 |
| — | BIOTIE THERAPIES OYJ | 50,000 | $718K | 0.1% | $19.98 | — | SPONSORED ADR | 09074D103 |
| — | NEOS THERAPEUTICS INC | 50,000 | $716K | 0.1% | $21.02 | — | COM | 64052L106 |
| — | NANOSTRING TECHNOLOGIES INC | 40,000 | $588K | 0.1% | $20.65 | — | COM | 63009R109 |
| — | PROVECTUS BIOPHARMACEUTICALS | 2,200,000 | $550K | 0.1% | $0.22 | — | *W EXP 06/24/202 | 74373P116 |
| — | THRESHOLD PHARMACEUTICALS INC | 1,000,000 | $480K | 0.1% | $0.48 | — | COM NEW | 885807206 |
| — | CELLECTAR BIOSCIENCES INC | 530,000 | $390K | 0.0% | $2.22 | — | COM NEW | 15117F203 |
| — | APPLIED GENETIC TECHNOL CORP | 17,110 | $349K | 0.0% | $23.10 | — | COM | 03820J100 |
| ADAPY | ADAPTIMMUNE THERAPEUTICS PLC | 25,000 | $302K | 0.0% | $18.32 | — | SPONDS ADR | 00653A107 |
| — | CELLECTAR BIOSCIENCES INC | 530,000 | $296K | 0.0% | $0.60 | — | *W EXP 08/19/201 | 15117F112 |
| — | REGULUS THERAPEUTICS INC | 30,656 | $267K | 0.0% | $14.62 | — | COM | 75915K101 |