EcoR1 Capital, LLC Quant / Systematic

CIK: 0001587114 · Show all filings

Period: Q4 2016 (← Previous) (Next →)

Filing Date: Feb 15, 2017

Total Value ($000): $314,111

Holdings (31)

IRWD IRONWOOD PHARMACEUTICALS INC 13.9%

Value ($000) $43,661 Shares 2,855,515 Est. Cost $9.38 Unrealized +34.7%

GLPG GALAPAGOS NV 11.5%

Value ($000) $36,032 Shares 561,341 Est. Cost $57.70 Unrealized —

— ASSEMBLY BIOSCIENCES INC 11.4%

Value ($000) $35,759 Shares 2,943,164 Est. Cost $8.38 Unrealized —

— ALEXION PHARMACEUTICALS INC 6.3%

Value ($000) $19,845 Shares 162,200 Est. Cost $122.35 Unrealized —

ASND ASCENDIS PHARMA A S 6.3%

Value ($000) $19,748 Shares 975,700 Est. Cost $20.21 Unrealized —

— THERAVANCE BIOPHARMA INC 6.2%

Value ($000) $19,327 Shares 17,000,000 Est. Cost $1.14 Unrealized —

ARDX ARDELYX INC 5.9%

Value ($000) $18,602 Shares 1,310,023 Est. Cost $10.48 Unrealized +35.5%

KURA KURA ONCOLOGY INC 4.9%

Value ($000) $15,410 Shares 2,611,906 Est. Cost $10.12 Unrealized -47.0%

— FIVE PRIME THERAPEUTICS INC 4.8%

Value ($000) $14,968 Shares 298,712 Est. Cost $52.39 Unrealized —

— FIBROGEN INC. 4.7%

Value ($000) $14,684 Shares 686,184 Est. Cost $24.72 Unrealized —

ACRS ACLARIS THERAPEUTICS INC 3.6%

Value ($000) $11,236 Shares 414,000 Est. Cost $25.50 Unrealized 0.0%

— ALLERGAN PLC 3.3%

Value ($000) $10,501 Shares 50,000 Est. Cost — Unrealized —

EDIT EDITAS MEDICINE INC COM 3.2%

Value ($000) $10,172 Shares 626,762 Est. Cost $15.18 Unrealized 0.0%

XNCR XENCOR INC 3.1%

Value ($000) $9,870 Shares 375,000 Est. Cost $24.05 Unrealized 0.0%

— CHIMERIX INC 2.1%

Value ($000) $6,512 Shares 1,415,687 Est. Cost $5.00 Unrealized —

— FATE THERAPEUTICS INC 2.0%

Value ($000) $6,368 Shares 2,537,026 Est. Cost $2.51 Unrealized —

— ATARA BIOTHERAPEUTICS INC 1.0%

Value ($000) $3,065 Shares 215,812 Est. Cost $14.20 Unrealized —

— ADVERUM BIOTECHNOLOGIES INC 0.8%

Value ($000) $2,536 Shares 874,447 Est. Cost $4.11 Unrealized —

— KINDRED BIOSCIENCES INC 0.8%

Value ($000) $2,427 Shares 571,126 Est. Cost $7.10 Unrealized —

— ATYR PHARMA INC 0.7%

Value ($000) $2,101 Shares 976,986 Est. Cost $2.15 Unrealized —

SNDX SYNDAX PHARMACEUTICALS INC 0.6%

Value ($000) $1,964 Shares 273,862 Est. Cost $12.54 Unrealized -12.6%

— EGALET CORP 0.5%

Value ($000) $1,701 Shares 222,300 Est. Cost $7.65 Unrealized —

— NABRIVA THERAPEUTICS AG 0.5%

Value ($000) $1,578 Shares 264,773 Est. Cost $9.50 Unrealized —

— DERMIRA INC 0.4%

Value ($000) $1,310 Shares 43,200 Est. Cost $31.44 Unrealized —

AGIO AGIOS PHARMACEUTICALS INC 0.3%

Value ($000) $972 Shares 23,300 Est. Cost $43.55 Unrealized +20.5%

— CHEMOCENTRYX INC 0.3%

Value ($000) $873 Shares 118,000 Est. Cost $6.04 Unrealized —

— SYROS PHARMACEUTICALS INC 0.2%

Value ($000) $773 Shares 63,596 Est. Cost $13.87 Unrealized —

CYTK CYTOKINETICS INC 0.2%

Value ($000) $667 Shares 54,879 Est. Cost $9.00 Unrealized +17.9%

— BIOPHARMX CORP 0.2%

Value ($000) $502 Shares 1,342,000 Est. Cost $0.37 Unrealized —

BMY BRISTOL MYERS SQUIBB CO 0.2%

Value ($000) $500 Shares 8,560 Est. Cost $39.53 Unrealized 0.0%

— CASCADIAN THERAPEUTICS INC 0.1%

Value ($000) $447 Shares 103,800 Est. Cost — Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
IRWD	IRONWOOD PHARMACEUTICALS INC	2,855,515	$43,661	13.9%	$9.38	+34.7%	—	46333X108
GLPG	GALAPAGOS NV	561,341	$36,032	11.5%	$57.70	—	—	36315X101
—	ASSEMBLY BIOSCIENCES INC	2,943,164	$35,759	11.4%	$8.38	—	—	045396108
—	ALEXION PHARMACEUTICALS INC	162,200	$19,845	6.3%	$122.35	—	—	015351109
ASND	ASCENDIS PHARMA A S	975,700	$19,748	6.3%	$20.21	—	—	04351P101
—	THERAVANCE BIOPHARMA INC	17,000,000	$19,327	6.2%	$1.14	—	—	88339KAA0
ARDX	ARDELYX INC	1,310,023	$18,602	5.9%	$10.48	+35.5%	—	039697107
KURA	KURA ONCOLOGY INC	2,611,906	$15,410	4.9%	$10.12	-47.0%	—	50127T109
—	FIVE PRIME THERAPEUTICS INC	298,712	$14,968	4.8%	$52.39	—	—	33830X104
—	FIBROGEN INC.	686,184	$14,684	4.7%	$24.72	—	—	31572Q808
ACRS	ACLARIS THERAPEUTICS INC	414,000	$11,236	3.6%	$25.50	0.0%	—	00461U105
—	ALLERGAN PLC	50,000	$10,501	3.3%	—	—	CALL	G0177J908
EDIT	EDITAS MEDICINE INC COM	626,762	$10,172	3.2%	$15.18	0.0%	—	28106W103
XNCR	XENCOR INC	375,000	$9,870	3.1%	$24.05	0.0%	—	98401F105
—	CHIMERIX INC	1,415,687	$6,512	2.1%	$5.00	—	—	16934W106
—	FATE THERAPEUTICS INC	2,537,026	$6,368	2.0%	$2.51	—	—	311900954
—	ATARA BIOTHERAPEUTICS INC	215,812	$3,065	1.0%	$14.20	—	—	046513107
—	ADVERUM BIOTECHNOLOGIES INC	874,447	$2,536	0.8%	$4.11	—	—	00773U108
—	KINDRED BIOSCIENCES INC	571,126	$2,427	0.8%	$7.10	—	—	494577109
—	ATYR PHARMA INC	976,986	$2,101	0.7%	$2.15	—	—	002120103
SNDX	SYNDAX PHARMACEUTICALS INC	273,862	$1,964	0.6%	$12.54	-12.6%	—	87164F105
—	EGALET CORP	222,300	$1,701	0.5%	$7.65	—	—	28226B104
—	NABRIVA THERAPEUTICS AG	264,773	$1,578	0.5%	$9.50	—	—	62957M104
—	DERMIRA INC	43,200	$1,310	0.4%	$31.44	—	—	24983L104
AGIO	AGIOS PHARMACEUTICALS INC	23,300	$972	0.3%	$43.55	+20.5%	—	00847X104
—	CHEMOCENTRYX INC	118,000	$873	0.3%	$6.04	—	—	01683L106
—	SYROS PHARMACEUTICALS INC	63,596	$773	0.2%	$13.87	—	—	87184Q107
CYTK	CYTOKINETICS INC	54,879	$667	0.2%	$9.00	+17.9%	—	23282W605
—	BIOPHARMX CORP	1,342,000	$502	0.2%	$0.37	—	—	09072X101
BMY	BRISTOL MYERS SQUIBB CO	8,560	$500	0.2%	$39.53	0.0%	—	110122108
—	CASCADIAN THERAPEUTICS INC	103,800	$447	0.1%	—	—	CALL	14740B901