RA CAPITAL MANAGEMENT, L.P. Diversified Active

Location: Boston, MA

CIK: 0001346824 · Show all filings

Period: Q1 2014 (← Previous) (Next →)

Filing Date: May 15, 2014

Total Value: $1.394B (100.0% shares, 0.0% debt)

Holdings (35)

GILD GILEAD SCIENCES INC 12.2%

Value $170M Shares 2,400,000 Share Price $70.86 Est. Cost/Share — Unrealized @ Report Date —

ACAD ACADIA PHARMACEUTICALS INC 9.2%

Value $128M Shares 5,250,000 Share Price $24.33 * Est. Cost/Share $13.77 Unrealized @ Report Date +83.7%

SGMO SANGAMO BIOSCIENCES INC 7.8%

Value $108M Shares 6,000,000 Share Price $18.08 * Est. Cost/Share $9.24 Unrealized @ Report Date +108.6%

SGMO SANGAMO BIOSCIENCES INC 6.8%

Value $94.42M Shares 5,222,053 Share Price $18.08 * Est. Cost/Share $9.24 Unrealized @ Report Date +108.6%

— ACHILLION PHARMACEUTICALS IN 5.5%

Value $76.87M Shares 23,366,007 Share Price $3.29 Est. Cost/Share $4.78 Unrealized @ Report Date —

— DICERNA PHARMACEUTICALS INC 4.9%

Value $68.61M Shares 2,428,571 Share Price $28.25 Est. Cost/Share $28.25 Unrealized @ Report Date —

— DYAX CORP 4.8%

Value $66.78M Shares 7,436,470 Share Price $8.98 Est. Cost/Share $7.78 Unrealized @ Report Date —

— THERAPEUTICSMD INC 4.5%

Value $62.08M Shares 9,838,449 Share Price $6.31 Est. Cost/Share $3.00 Unrealized @ Report Date —

— OPHTHOTECH CORP 4.4%

Value $62M Shares 1,737,856 Share Price $35.67 Est. Cost/Share $32.61 Unrealized @ Report Date —

ENTA ENANTA PHARMACEUTICALS INC 4.4%

Value $61.63M Shares 1,541,078 Share Price $39.99 * Est. Cost/Share $36.32 Unrealized @ Report Date 0.0%

PRTA PROTHENA CORP PLC 4.3%

Value $59.57M Shares 1,554,918 Share Price $38.31 * Est. Cost/Share $15.16 Unrealized @ Report Date +112.7%

— ARROWHEAD RESH CORP 3.5%

Value $48.31M Shares 2,941,916 Share Price $16.42 Est. Cost/Share $9.89 Unrealized @ Report Date —

BCRX BIOCRYST PHARMACEUTICALS 3.3%

Value $46M Shares 4,347,456 Share Price $10.58 Est. Cost/Share $5.07 Unrealized @ Report Date +110.2%

— NOVAVAX INC 3.2%

Value $45.02M Shares 9,938,250 Share Price $4.53 Est. Cost/Share $2.24 Unrealized @ Report Date —

— DYNAVAX TECHNOLOGIES CORP 2.3%

Value $32.33M Shares 17,883,954 Share Price $1.81 Est. Cost/Share $1.67 Unrealized @ Report Date —

— SUNESIS PHARMACEUTICALS INC 2.3%

Value $32.19M Shares 4,869,261 Share Price $6.61 Est. Cost/Share $5.18 Unrealized @ Report Date —

XNCR XENCOR INC 2.3%

Value $31.96M Shares 2,725,000 Share Price $11.73 * Est. Cost/Share $8.58 Unrealized @ Report Date +22.5%

PTCT PTC THERAPEUTICS INC 1.8%

Value $25.66M Shares 981,761 Share Price $26.14 * Est. Cost/Share $19.69 Unrealized @ Report Date +36.5%

— REPROS THERAPEUTICS INC 1.8%

Value $25.53M Shares 1,439,048 Share Price $17.74 Est. Cost/Share $17.74 Unrealized @ Report Date —

— TESARO INC 1.5%

Value $20.64M Shares 700,000 Share Price $29.48 Est. Cost/Share $28.24 Unrealized @ Report Date —

NBIX NEUROCRINE BIOSCIENCES INC 1.3%

Value $18.82M Shares 1,169,084 Share Price $16.10 * Est. Cost/Share $17.10 Unrealized @ Report Date 0.0%

— DERMA SCIENCES INC 1.2%

Value $16.98M Shares 1,339,039 Share Price $12.68 Est. Cost/Share $13.35 Unrealized @ Report Date —

— MIRATI THERAPEUTICS INC 0.9%

Value $12.53M Shares 656,767 Share Price $19.07 Est. Cost/Share $15.39 Unrealized @ Report Date —

— BLUEBIRD BIO INC 0.8%

Value $10.63M Shares 467,418 Share Price $22.74 Est. Cost/Share $26.96 Unrealized @ Report Date —

— PSIVIDA CORP 0.8%

Value $10.48M Shares 2,555,659 Share Price $4.10 Est. Cost/Share $4.04 Unrealized @ Report Date —

— INTERMUNE INC 0.7%

Value $10.07M Shares 300,801 Share Price $33.47 Est. Cost/Share $33.47 Unrealized @ Report Date —

— ACHILLION PHARMACEUTICALS IN 0.7%

Value $9.87M Shares 3,000,000 Share Price $3.29 Est. Cost/Share $4.78 Unrealized @ Report Date —

— FLEXION THERAPEUTICS INC 0.5%

Value $7.403M Shares 450,000 Share Price $16.45 Est. Cost/Share $16.45 Unrealized @ Report Date —

ACAD ACADIA PHARMACEUTICALS INC 0.4%

Value $6.083M Shares 250,000 Share Price $24.33 * Est. Cost/Share $13.77 Unrealized @ Report Date +83.7%

— OCERA THERAPEUTICS INC 0.4%

Value $5.568M Shares 527,797 Share Price $10.55 Est. Cost/Share $11.51 Unrealized @ Report Date —

MGNX MACROGENICS INC 0.4%

Value $5.549M Shares 199,398 Share Price $27.83 * Est. Cost/Share $26.16 Unrealized @ Report Date +35.0%

— ALIMERA SCIENCES INC 0.4%

Value $5.26M Shares 666,667 Share Price $7.89 Est. Cost/Share $7.89 Unrealized @ Report Date —

— MEI PHARMA INC 0.3%

Value $4.545M Shares 408,333 Share Price $11.13 Est. Cost/Share $8.01 Unrealized @ Report Date —

— DYAX CORP 0.3%

Value $4.49M Shares 500,000 Share Price $8.98 Est. Cost/Share $7.78 Unrealized @ Report Date —

— PRANA BIOTECHNOLOGY LTD 0.0%

Value $280K Shares 100,000 Share Price $2.80 Est. Cost/Share — Unrealized @ Report Date —

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
GILD	GILEAD SCIENCES INC	2,400,000	$170M	12.2%	$70.86	—	—	Put	375558103
ACAD	ACADIA PHARMACEUTICALS INC	5,250,000	$128M	9.2%	$24.33 *	$13.77	+83.7%	Call	004225108
SGMO	SANGAMO BIOSCIENCES INC	6,000,000	$108M	7.8%	$18.08 *	$9.24	+108.6%	Call	800677106
SGMO	SANGAMO BIOSCIENCES INC	5,222,053	$94.42M	6.8%	$18.08 *	$9.24	+108.6%	COM	800677106
—	ACHILLION PHARMACEUTICALS IN	23,366,007	$76.87M	5.5%	$3.29	$4.78	—	COM	00448Q201
—	DICERNA PHARMACEUTICALS INC	2,428,571	$68.61M	4.9%	$28.25	$28.25	—	COM	253031108
—	DYAX CORP	7,436,470	$66.78M	4.8%	$8.98	$7.78	—	COM	26746E103
—	THERAPEUTICSMD INC	9,838,449	$62.08M	4.5%	$6.31	$3.00	—	COM	88338N107
—	OPHTHOTECH CORP	1,737,856	$62M	4.4%	$35.67	$32.61	—	COM	683745103
ENTA	ENANTA PHARMACEUTICALS INC	1,541,078	$61.63M	4.4%	$39.99 *	$36.32	0.0%	COM	29251M106
PRTA	PROTHENA CORP PLC	1,554,918	$59.57M	4.3%	$38.31 *	$15.16	+112.7%	SHS	G72800108
—	ARROWHEAD RESH CORP	2,941,916	$48.31M	3.5%	$16.42	$9.89	—	COM NEW	042797209
BCRX	BIOCRYST PHARMACEUTICALS	4,347,456	$46M	3.3%	$10.58	$5.07	+110.2%	COM	09058V103
—	NOVAVAX INC	9,938,250	$45.02M	3.2%	$4.53	$2.24	—	COM	670002104
—	DYNAVAX TECHNOLOGIES CORP	17,883,954	$32.33M	2.3%	$1.81	$1.67	—	COM	268158102
—	SUNESIS PHARMACEUTICALS INC	4,869,261	$32.19M	2.3%	$6.61	$5.18	—	COM NEW	867328601
XNCR	XENCOR INC	2,725,000	$31.96M	2.3%	$11.73 *	$8.58	+22.5%	COM	98401F105
PTCT	PTC THERAPEUTICS INC	981,761	$25.66M	1.8%	$26.14 *	$19.69	+36.5%	COM	69366J200
—	REPROS THERAPEUTICS INC	1,439,048	$25.53M	1.8%	$17.74	$17.74	—	COM NEW	76028H209
—	TESARO INC	700,000	$20.64M	1.5%	$29.48	$28.24	—	COM	881569107
NBIX	NEUROCRINE BIOSCIENCES INC	1,169,084	$18.82M	1.3%	$16.10 *	$17.10	0.0%	COM	64125C109
—	DERMA SCIENCES INC	1,339,039	$16.98M	1.2%	$12.68	$13.35	—	COM PAR $.01	249827502
—	MIRATI THERAPEUTICS INC	656,767	$12.53M	0.9%	$19.07	$15.39	—	COM	60468T105
—	BLUEBIRD BIO INC	467,418	$10.63M	0.8%	$22.74	$26.96	—	COM	09609G100
—	PSIVIDA CORP	2,555,659	$10.48M	0.8%	$4.10	$4.04	—	COM	74440J101
—	INTERMUNE INC	300,801	$10.07M	0.7%	$33.47	$33.47	—	COM	45884X103
—	ACHILLION PHARMACEUTICALS IN	3,000,000	$9.87M	0.7%	$3.29	$4.78	—	Call	00448Q201
—	FLEXION THERAPEUTICS INC	450,000	$7.403M	0.5%	$16.45	$16.45	—	COM	33938J106
ACAD	ACADIA PHARMACEUTICALS INC	250,000	$6.083M	0.4%	$24.33 *	$13.77	+83.7%	COM	004225108
—	OCERA THERAPEUTICS INC	527,797	$5.568M	0.4%	$10.55	$11.51	—	COM	67552A108
MGNX	MACROGENICS INC	199,398	$5.549M	0.4%	$27.83 *	$26.16	+35.0%	COM	556099109
—	ALIMERA SCIENCES INC	666,667	$5.26M	0.4%	$7.89	$7.89	—	COM	016259103
—	MEI PHARMA INC	408,333	$4.545M	0.3%	$11.13	$8.01	—	COM NEW	55279B202
—	DYAX CORP	500,000	$4.49M	0.3%	$8.98	$7.78	—	Call	26746E103
—	PRANA BIOTECHNOLOGY LTD	100,000	$280K	0.0%	$2.80	—	—	Call	739727105