RA CAPITAL MANAGEMENT, L.P. Diversified Active

Location: Boston, MA

CIK: 0001346824 · Show all filings

Period: Q3 2017 (← Previous) (Next →)

Filing Date: Nov 14, 2017

Total Value: $1.107B (100.0% shares, 0.0% debt)

Holdings (27)

ASND ASCENDIS PHARMA A S 18.3%

Value $202M Shares 5,580,690 Share Price $36.25 Est. Cost/Share $17.96 Unrealized @ Report Date —

WVE WAVE LIFE SCIENCES LTD 13.9%

Value $154M Shares 7,088,651 Share Price $21.75 * Est. Cost/Share $15.68 Unrealized @ Report Date +28.2%

— AVEXIS INC 10.8%

Value $120M Shares 1,238,181 Share Price $96.73 Est. Cost/Share $31.86 Unrealized @ Report Date —

— BIOHAVEN PHARMACTL HLDG CO LTD 6.7%

Value $74.66M Shares 1,997,278 Share Price $37.38 Est. Cost/Share $25.00 Unrealized @ Report Date —

— ACHILLION PHARMACEUTICALS INC 5.5%

Value $61.21M Shares 13,633,220 Share Price $4.49 Est. Cost/Share $6.18 Unrealized @ Report Date —

— IGNYTA INC 4.6%

Value $50.72M Shares 4,106,601 Share Price $12.35 Est. Cost/Share $9.96 Unrealized @ Report Date —

— G1 THERAPEUTICS INC 4.5%

Value $49.79M Shares 2,684,244 Share Price $18.55 Est. Cost/Share $17.44 Unrealized @ Report Date —

— KALA PHARMACEUTICALS INC 4.4%

Value $48.27M Shares 2,113,236 Share Price $22.84 Est. Cost/Share $22.84 Unrealized @ Report Date —

— MYOVANT SCIENCES LTD 4.0%

Value $43.79M Shares 2,830,455 Share Price $15.47 Est. Cost/Share $12.11 Unrealized @ Report Date —

— AVEO PHARMACEUTICALS INC 3.7%

Value $41.35M Shares 11,328,646 Share Price $3.65 Est. Cost/Share $2.59 Unrealized @ Report Date —

BCRX BIOCRYST PHARMACEUTICALS 3.3%

Value $36.6M Shares 6,984,692 Share Price $5.24 * Est. Cost/Share $7.39 Unrealized @ Report Date -30.7%

— ZOGENIX INC 3.1%

Value $34.78M Shares 992,268 Share Price $35.05 Est. Cost/Share $13.32 Unrealized @ Report Date —

INSM INSMED INC 2.0%

Value $22.56M Shares 722,714 Share Price $31.21 * Est. Cost/Share $19.05 Unrealized @ Report Date 0.0%

— KADMON HLDGS INC 2.0%

Value $22.33M Shares 6,666,666 Share Price $3.35 Est. Cost/Share $3.35 Unrealized @ Report Date —

— ACORDA THERAPEUTICS INC 1.9%

Value $21.29M Shares 900,259 Share Price $23.65 Est. Cost/Share $20.41 Unrealized @ Report Date —

— IMMUNOMEDICS INC 1.9%

Value $20.67M Shares 1,478,742 Share Price $13.98 Est. Cost/Share $13.98 Unrealized @ Report Date —

— RA PHARMACEUTICALS INC 1.8%

Value $19.74M Shares 1,351,808 Share Price $14.60 Est. Cost/Share $15.19 Unrealized @ Report Date —

SGMO SANGAMO THERAPEUTICS INC 1.7%

Value $18.75M Shares 1,250,000 Share Price $15.00 * Est. Cost/Share $6.42 Unrealized @ Report Date +72.3%

— DICERNA PHARMACEUTICALS INC 1.3%

Value $13.96M Shares 2,428,571 Share Price $5.75 Est. Cost/Share $28.25 Unrealized @ Report Date —

— AQUINOX PHARMACEUTICALS INC 0.9%

Value $10.09M Shares 710,682 Share Price $14.19 Est. Cost/Share $14.19 Unrealized @ Report Date —

— CLEMENTIA PHARMACEUTICALS INC COM NPV 0.9%

Value $9.887M Shares 585,403 Share Price $16.89 Est. Cost/Share $16.89 Unrealized @ Report Date —

TGTX TG THERAPEUTICS INC 0.7%

Value $8.295M Shares 700,000 Share Price $11.85 * Est. Cost/Share $10.06 Unrealized @ Report Date +13.2%

KRYS KRYSTAL BIOTECH INC 0.6%

Value $6.979M Shares 700,000 Share Price $9.97 Est. Cost/Share $10.08 Unrealized @ Report Date 0.0%

VNDA VANDA PHARMACEUTICALS INC 0.4%

Value $4.367M Shares 243,971 Share Price $17.90 * Est. Cost/Share $16.73 Unrealized @ Report Date 0.0%

KALV KALVISTA PHARMACEUTICALS INC 0.4%

Value $4.35M Shares 591,070 Share Price $7.36 * Est. Cost/Share $7.37 Unrealized @ Report Date -3.3%

— CHIASMA INC 0.3%

Value $3.561M Shares 1,396,400 Share Price $2.55 Est. Cost/Share $2.55 Unrealized @ Report Date —

— PROTEON THERAPEUTICS INC 0.2%

Value $2.675M Shares 1,337,462 Share Price $2.00 Est. Cost/Share $1.53 Unrealized @ Report Date —

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
ASND	ASCENDIS PHARMA A S	5,580,690	$202M	18.3%	$36.25	$17.96	—	SPONSORED ADR	04351P101
WVE	WAVE LIFE SCIENCES LTD	7,088,651	$154M	13.9%	$21.75 *	$15.68	+28.2%	SHS	Y95308105
—	AVEXIS INC	1,238,181	$120M	10.8%	$96.73	$31.86	—	COM	05366U100
—	BIOHAVEN PHARMACTL HLDG CO LTD	1,997,278	$74.66M	6.7%	$37.38	$25.00	—	COM	G11196105
—	ACHILLION PHARMACEUTICALS INC	13,633,220	$61.21M	5.5%	$4.49	$6.18	—	COM	00448Q201
—	IGNYTA INC	4,106,601	$50.72M	4.6%	$12.35	$9.96	—	COM	451731103
—	G1 THERAPEUTICS INC	2,684,244	$49.79M	4.5%	$18.55	$17.44	—	COM	3621LQ109
—	KALA PHARMACEUTICALS INC	2,113,236	$48.27M	4.4%	$22.84	$22.84	—	COM	483119103
—	MYOVANT SCIENCES LTD	2,830,455	$43.79M	4.0%	$15.47	$12.11	—	COM	G637AM102
—	AVEO PHARMACEUTICALS INC	11,328,646	$41.35M	3.7%	$3.65	$2.59	—	COM	053588109
BCRX	BIOCRYST PHARMACEUTICALS	6,984,692	$36.6M	3.3%	$5.24 *	$7.39	-30.7%	COM	09058V103
—	ZOGENIX INC	992,268	$34.78M	3.1%	$35.05	$13.32	—	COM NEW	98978L204
INSM	INSMED INC	722,714	$22.56M	2.0%	$31.21 *	$19.05	0.0%	COM PAR $.01	457669307
—	KADMON HLDGS INC	6,666,666	$22.33M	2.0%	$3.35	$3.35	—	COM	48283N106
—	ACORDA THERAPEUTICS INC	900,259	$21.29M	1.9%	$23.65	$20.41	—	COM	00484M106
—	IMMUNOMEDICS INC	1,478,742	$20.67M	1.9%	$13.98	$13.98	—	COM	452907108
—	RA PHARMACEUTICALS INC	1,351,808	$19.74M	1.8%	$14.60	$15.19	—	COM	74933V108
SGMO	SANGAMO THERAPEUTICS INC	1,250,000	$18.75M	1.7%	$15.00 *	$6.42	+72.3%	COM	800677106
—	DICERNA PHARMACEUTICALS INC	2,428,571	$13.96M	1.3%	$5.75	$28.25	—	COM	253031108
—	AQUINOX PHARMACEUTICALS INC	710,682	$10.09M	0.9%	$14.19	$14.19	—	COM	03842B100
—	CLEMENTIA PHARMACEUTICALS INC COM NPV	585,403	$9.887M	0.9%	$16.89	$16.89	—	COM	185575107
TGTX	TG THERAPEUTICS INC	700,000	$8.295M	0.7%	$11.85 *	$10.06	+13.2%	COM	88322Q108
KRYS	KRYSTAL BIOTECH INC	700,000	$6.979M	0.6%	$9.97	$10.08	0.0%	COM	501147102
VNDA	VANDA PHARMACEUTICALS INC	243,971	$4.367M	0.4%	$17.90 *	$16.73	0.0%	COM	921659108
KALV	KALVISTA PHARMACEUTICALS INC	591,070	$4.35M	0.4%	$7.36 *	$7.37	-3.3%	COM	483497103
—	CHIASMA INC	1,396,400	$3.561M	0.3%	$2.55	$2.55	—	COM	16706W102
—	PROTEON THERAPEUTICS INC	1,337,462	$2.675M	0.2%	$2.00	$1.53	—	COM	74371L109