RA CAPITAL MANAGEMENT, L.P. Diversified Active

CIK: 0001346824 · Show all filings

Period: Q4 2017 (← Previous) (Next →)

Filing Date: Feb 14, 2018

Total Value ($000): $1,195,149 (100.0% shares, 0.0% debt)

Holdings (27)

WVE WAVE LIFE SCIENCES LTD 22.1%

Value ($000) $263,673 Shares 7,512,049 Est. Cost $16.44 Unrealized +77.3%

ASND ASCENDIS PHARMA A S 18.7%

Value ($000) $223,562 Shares 5,580,690 Est. Cost $17.96 Unrealized —

— AVEXIS INC 10.8%

Value ($000) $129,625 Shares 1,171,278 Est. Cost $31.86 Unrealized —

— SAGE THERAPEUTICS INC 6.3%

Value ($000) $74,972 Shares 455,173 Est. Cost $164.71 Unrealized —

IFRX INFLARX NV 5.0%

Value ($000) $60,254 Shares 2,876,080 Est. Cost $17.97 Unrealized 0.0%

— BIOHAVEN PHARMACTL HLDG CO LTD 4.5%

Value ($000) $53,887 Shares 1,997,278 Est. Cost $25.00 Unrealized —

— ZOGENIX INC 3.8%

Value ($000) $45,868 Shares 1,145,268 Est. Cost $16.89 Unrealized —

— DICERNA PHARMACEUTICALS INC 3.8%

Value ($000) $44,839 Shares 4,965,513 Est. Cost $18.43 Unrealized —

— KALA PHARMACEUTICALS INC 3.3%

Value ($000) $39,074 Shares 2,113,236 Est. Cost $22.84 Unrealized —

— MYOVANT SCIENCES LTD 3.0%

Value ($000) $35,777 Shares 2,830,455 Est. Cost $12.11 Unrealized —

— SCPHARMACEUTICALS INC 2.9%

Value ($000) $34,543 Shares 2,857,143 Est. Cost $12.09 Unrealized —

BCRX BIOCRYST PHARMACEUTICALS 2.9%

Value ($000) $34,295 Shares 6,984,692 Est. Cost $7.39 Unrealized -34.5%

— KADMON HLDGS INC 1.9%

Value ($000) $22,695 Shares 6,269,342 Est. Cost $3.35 Unrealized —

APLS APELLIS PHARMACEUTICALS INC 1.6%

Value ($000) $19,530 Shares 900,000 Est. Cost $14.72 Unrealized 0.0%

— ENDOCYTE INC 1.2%

Value ($000) $14,401 Shares 3,364,648 Est. Cost $4.28 Unrealized —

SPRO SPERO THERAPEUTICS INC 1.2%

Value ($000) $14,401 Shares 1,225,647 Est. Cost $12.27 Unrealized 0.0%

— AVEO PHARMACEUTICALS INC 1.2%

Value ($000) $14,125 Shares 5,062,759 Est. Cost $2.59 Unrealized —

KALV KALVISTA PHARMACEUTICALS INC 1.2%

Value ($000) $14,050 Shares 1,441,070 Est. Cost $9.16 Unrealized +13.6%

— RA PHARMACEUTICALS INC 1.0%

Value ($000) $11,490 Shares 1,351,808 Est. Cost $15.19 Unrealized —

— SUNESIS PHARMACEUTICALS INC 1.0%

Value ($000) $11,427 Shares 3,096,840 Est. Cost $3.69 Unrealized —

— CLEMENTIA PHARMACEUTICALS INC COM NPV 0.9%

Value ($000) $11,111 Shares 585,403 Est. Cost $16.89 Unrealized —

KRYS KRYSTAL BIOTECH INC 0.6%

Value ($000) $7,364 Shares 700,000 Est. Cost $10.08 Unrealized -0.6%

ARGX ARGENX SE 0.4%

Value ($000) $4,787 Shares 75,816 Est. Cost $63.14 Unrealized —

— G1 THERAPEUTICS INC 0.3%

Value ($000) $3,170 Shares 159,780 Est. Cost $17.44 Unrealized —

— PROTEON THERAPEUTICS INC 0.2%

Value ($000) $2,541 Shares 1,337,462 Est. Cost $1.53 Unrealized —

— CHIASMA INC 0.2%

Value ($000) $2,001 Shares 1,176,806 Est. Cost $2.55 Unrealized —

— ACHILLION PHARMACEUTICALS INC 0.1%

Value ($000) $1,687 Shares 585,890 Est. Cost $6.18 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
WVE	WAVE LIFE SCIENCES LTD	7,512,049	$263,673	22.1%	$16.44	+77.3%	SHS	Y95308105
ASND	ASCENDIS PHARMA A S	5,580,690	$223,562	18.7%	$17.96	—	SPONSORED ADR	04351P101
—	AVEXIS INC	1,171,278	$129,625	10.8%	$31.86	—	COM	05366U100
—	SAGE THERAPEUTICS INC	455,173	$74,972	6.3%	$164.71	—	COM	78667J108
IFRX	INFLARX NV	2,876,080	$60,254	5.0%	$17.97	0.0%	COM	N44821101
—	BIOHAVEN PHARMACTL HLDG CO LTD	1,997,278	$53,887	4.5%	$25.00	—	COM	G11196105
—	ZOGENIX INC	1,145,268	$45,868	3.8%	$16.89	—	COM NEW	98978L204
—	DICERNA PHARMACEUTICALS INC	4,965,513	$44,839	3.8%	$18.43	—	COM	253031108
—	KALA PHARMACEUTICALS INC	2,113,236	$39,074	3.3%	$22.84	—	COM	483119103
—	MYOVANT SCIENCES LTD	2,830,455	$35,777	3.0%	$12.11	—	COM	G637AM102
—	SCPHARMACEUTICALS INC	2,857,143	$34,543	2.9%	$12.09	—	COM	810648105
BCRX	BIOCRYST PHARMACEUTICALS	6,984,692	$34,295	2.9%	$7.39	-34.5%	COM	09058V103
—	KADMON HLDGS INC	6,269,342	$22,695	1.9%	$3.35	—	COM	48283N106
APLS	APELLIS PHARMACEUTICALS INC	900,000	$19,530	1.6%	$14.72	0.0%	COM	03753U106
—	ENDOCYTE INC	3,364,648	$14,401	1.2%	$4.28	—	COM	29269A102
SPRO	SPERO THERAPEUTICS INC	1,225,647	$14,401	1.2%	$12.27	0.0%	COM	84833T103
—	AVEO PHARMACEUTICALS INC	5,062,759	$14,125	1.2%	$2.59	—	COM	053588109
KALV	KALVISTA PHARMACEUTICALS INC	1,441,070	$14,050	1.2%	$9.16	+13.6%	COM	483497103
—	RA PHARMACEUTICALS INC	1,351,808	$11,490	1.0%	$15.19	—	COM	74933V108
—	SUNESIS PHARMACEUTICALS INC	3,096,840	$11,427	1.0%	$3.69	—	COM PAR	867328700
—	CLEMENTIA PHARMACEUTICALS INC COM NPV	585,403	$11,111	0.9%	$16.89	—	COM	185575107
KRYS	KRYSTAL BIOTECH INC	700,000	$7,364	0.6%	$10.08	-0.6%	COM	501147102
ARGX	ARGENX SE	75,816	$4,787	0.4%	$63.14	—	SPONSORED ADR	04016X101
—	G1 THERAPEUTICS INC	159,780	$3,170	0.3%	$17.44	—	COM	3621LQ109
—	PROTEON THERAPEUTICS INC	1,337,462	$2,541	0.2%	$1.53	—	COM	74371L109
—	CHIASMA INC	1,176,806	$2,001	0.2%	$2.55	—	COM	16706W102
—	ACHILLION PHARMACEUTICALS INC	585,890	$1,687	0.1%	$6.18	—	COM	00448Q201