Location: Miami Beach, FL
CIK: 0001535610 · Show all filings
Period: Q1 2018 (← Previous) (Next →)
Filing Date: May 15, 2018
Total Value: $841M (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| — | SPDR S&P 500 | 9,867 | $260M | 30.9% | $26314.99 | — | — | Put | 78462F953 |
| — | ASTRAZENECA PLC | 14,645 | $51.21M | 6.1% | $3497.03 | — | — | Call | 046353908 |
| BIIB | BIOGEN INC | 182,898 | $50.08M | 6.0% | $273.82 * | $310.41 | 0.0% | COM | 09062X103 |
| — | BIOGEN INC | 2,071 | $48.93M | 5.8% | $23625.30 | — | — | Put | 09062X953 |
| — | ESPERION THERAPEUTICS INC | 6,053 | $43.78M | 5.2% | $7232.94 | — | — | Put | 29664W955 |
| — | ISHARES RUSSELL 2000 | 2,875 | $43.65M | 5.2% | $15182.96 | — | — | Put | 464287955 |
| — | ISHARES RUSSELL 2000 | 2,500 | $37.96M | 4.5% | $15183.20 | — | — | Call | 464287905 |
| — | ASTRAZENECA PLC | 8,380 | $29.3M | 3.5% | $3497.02 | — | — | Put | 046353958 |
| — | SAREPTA THERAPEUTICS INC | 2,333 | $17.29M | 2.1% | $7408.92 | — | — | Call | 803607900 |
| — | ZOGENIX INC | 4,059 | $16.26M | 1.9% | $4004.93 | — | — | Call | 98978L904 |
| — | ODONATE THERAPEUTICS INC | 734,272 | $15.55M | 1.8% | $21.18 | $25.00 | — | COM | 676079106 |
| — | MERCK & CO INC | 2,490 | $13.56M | 1.6% | $5446.99 | — | — | Call | 58933Y905 |
| SPY | SPDR S&P 500 | 44,500 | $11.71M | 1.4% | $263.15 | $263.15 | — | TR | 78462F103 |
| — | INCYTE CORP | 1,295 | $10.79M | 1.3% | $8332.82 | — | — | Put | 45337C952 |
| — | SPDR S&P BIOTECH | 1,122 | $9.843M | 1.2% | $8772.73 | — | — | Put | 78464A950 |
| — | INCYTE CORP | 1,140 | $9.5M | 1.1% | $8333.33 | — | — | Call | 45337C902 |
| — | UNUM THERAPEUTICS INC | 843,850 | $9.375M | 1.1% | $11.11 | $11.11 | — | COM | 903214104 |
| — | NEKTAR THERAPEUTICS | 725 | $7.704M | 0.9% | $10626.21 | — | — | Call | 640268908 |
| INCY | INCYTE CORP | 81,861 | $6.821M | 0.8% | $83.32 * | $90.16 | 0.0% | COM | 45337C102 |
| — | SPARK THERAPEUTICS INC | 1,015 | $6.759M | 0.8% | $6659.11 | — | — | Put | 84652J953 |
| — | ALEXION PHARMACEUTICALS INC | 593 | $6.61M | 0.8% | $11146.71 | — | — | Call | 015351909 |
| — | SAREPTA THERAPEUTICS INC | 888 | $6.579M | 0.8% | $7408.78 | — | — | Put | 803607950 |
| — | SANGAMO THERAPEUTICS INC | 3,386 | $6.433M | 0.8% | $1899.88 | — | — | Put | 800677956 |
| — | NEKTAR THERAPEUTICS | 58,831 | $6.251M | 0.7% | $106.25 | $90.43 | — | COM | 640268108 |
| — | SPARK THERAPEUTICS INC | 775 | $5.161M | 0.6% | $6659.35 | — | — | Call | 84652J903 |
| — | ALKERMES PLC | 676 | $3.918M | 0.5% | $5795.86 | — | — | Call | G01767905 |
| — | ESPERION THERAPEUTICS INC | 538 | $3.891M | 0.5% | $7232.34 | — | — | Call | 29664W905 |
| — | GLOBAL BLOOD THERAPEUTICS INC | 758 | $3.661M | 0.4% | $4829.82 | — | — | Call | 37890U908 |
| — | ARCADIA BIOSCIENCES INC | 150,376 | $3.611M | 0.4% | $24.01 | $24.01 | — | COM | 039014204 |
| — | ABBVIE INC | 369 | $3.493M | 0.4% | $9466.12 | — | — | Call | 00287Y909 |
| — | ALNYLAM PHARMACEUTICALS INC | 250 | $2.978M | 0.4% | $11912.00 | — | — | Put | 02043Q957 |
| — | NEKTAR THERAPEUTICS | 280 | $2.975M | 0.4% | $10625.00 | — | — | Put | 640268958 |
| — | ZOGENIX INC | 687 | $2.751M | 0.3% | $4004.37 | — | — | Put | 98978L954 |
| SGMO | SANGAMO THERAPEUTICS INC | 142,136 | $2.701M | 0.3% | $19.00 * | $21.38 | 0.0% | COM | 800677106 |
| — | AMARIN CORP PLC | 8,319 | $2.504M | 0.3% | $301.00 | — | — | Call | 023111906 |
| — | AVEO PHARMACEUTICALS INC | 8,571 | $2.486M | 0.3% | $290.05 | — | — | Call | 053588909 |
| — | ACCELERON PHARMA INC | 524 | $2.049M | 0.2% | $3910.31 | — | — | Put | 00434H958 |
| — | CITIUS PHARMACEUTICALS INC | 641,201 | $1.988M | 0.2% | $3.10 | $3.36 | — | COM | 17322U207 |
| — | AMYRIS INC | 2,821 | $1.887M | 0.2% | $668.91 | — | — | Put | 03236M950 |
| — | ONCOBIOLOGICS INC | 2,108,249 | $1.876M | 0.2% | $0.89 | $3.31 | — | COM | 68235M105 |
| — | ACHAOGEN INC | 1,405 | $1.819M | 0.2% | $1294.66 | — | — | Put | 004449954 |
| — | BRISTOL MYERS SQUIBB | 281 | $1.777M | 0.2% | $6323.84 | — | — | Put | 110122958 |
| — | CAN FITE BIOPHARMA LTD | 1,228,091 | $1.768M | 0.2% | $1.44 | $1.44 | — | ADR | 13471N102 |
| — | SOLENO THERAPEUTICS | 917,835 | $1.661M | 0.2% | $1.81 | $1.80 | — | COM | 834203200 |
| — | NOVAN INC | 545,149 | $1.597M | 0.2% | $2.93 | $2.93 | — | COM | 66988N106 |
| — | CELLECT BIOTECHNOLOGY LTD | 243,980 | $1.557M | 0.2% | $6.38 | $6.38 | — | ADS | 15116C102 |
| — | AMICUS THERAPEUTICS INC | 1,005 | $1.512M | 0.2% | $1504.48 | — | — | Call | 03152W909 |
| — | AMICUS THERAPEUTICS INC | 1,000 | $1.504M | 0.2% | $1504.00 | — | — | Put | 03152W959 |
| — | PAVMED INC | 908,817 | $1.49M | 0.2% | $1.64 | $1.64 | — | COM | 70387R106 |
| BMY | BRISTOL MYERS SQUIBB | 23,312 | $1.474M | 0.2% | $63.23 * | $43.12 | +11.6% | COM | 110122108 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 11,500 | $1.37M | 0.2% | $119.13 * | $125.65 | +2.6% | COM | 02043Q107 |
| ESPR | ESPERION THERAPEUTICS INC | 18,823 | $1.361M | 0.2% | $72.31 | $50.54 | +45.3% | COM | 29664W105 |
| — | PROTHENA CORPORATION PLC | 431 | $1.336M | 0.2% | $3099.77 | — | — | Put | G72800958 |
| — | ELEVEN BIOTHERAPEUTICS INC | 1,226,117 | $1.287M | 0.2% | $1.05 | $1.05 | — | COM | 286221106 |
| — | INSMED INC | 543 | $1.223M | 0.1% | $2252.30 | — | — | Put | 457669957 |
| — | OVASCIENCE INC | 1,461,525 | $1.185M | 0.1% | $0.81 | $1.31 | — | COM | 69014Q101 |
| — | ZOSANO PHARMA CORO | 233,779 | $1.178M | 0.1% | $5.04 | $5.04 | — | COM | 98979H202 |
| — | VERSARTIS INC | 702,364 | $1.159M | 0.1% | $1.65 | $2.38 | — | COM | 92529L102 |
| — | ADVERUM BIOTECHNOLOGIES INC | 198,964 | $1.154M | 0.1% | $5.80 | $3.50 | — | COM | 00773U108 |
| — | ALEXION PHARMACEUTICALS INC | 96 | $1.07M | 0.1% | $11145.83 | — | — | Put | 015351959 |
| — | SELLAS LIFE SCIENCES GROUP INC | 309,207 | $1.067M | 0.1% | $3.45 | $3.45 | — | COM | 81642T100 |
| — | NEUROMETRIX INC | 710,389 | $1.002M | 0.1% | $1.41 | $1.53 | — | COM | 641255708 |
| — | ADOMANI INC COM | 843,407 | $995K | 0.1% | $1.18 | $1.18 | — | COM | 00726A100 |
| FOLD | AMICUS THERAPEUTICS INC | 64,910 | $976K | 0.1% | $15.04 | $15.22 | 0.0% | COM | 03152W109 |
| AKBA | AKEBIA THERAPEUTICS INC | 102,338 | $975K | 0.1% | $9.53 * | $13.99 | 0.0% | COM | 00972D105 |
| — | ACHAOGEN INC | 713 | $923K | 0.1% | $1294.53 | — | — | Call | 004449904 |
| — | ALKERMES PLC | 157 | $910K | 0.1% | $5796.18 | — | — | Put | G01767955 |
| — | EYENOVIA INC | 97,770 | $908K | 0.1% | $9.29 | $9.29 | — | COM | 30234E104 |
| — | SYNERGY PHARMACEUTICALS INC | 4,954 | $907K | 0.1% | $183.08 | — | — | Call | 871639908 |
| — | AMPLIPHI BIOSCIENCES CORP | 831,961 | $907K | 0.1% | $1.09 | $1.09 | — | COM | 03211P301 |
| PRTA | PROTHENA CORPORATION PLC | 24,500 | $899K | 0.1% | $36.69 | $50.91 | -28.6% | SHS | G72800108 |
| — | OPGEN INC | 521,076 | $875K | 0.1% | $1.68 | $0.99 | — | COM | 68373L109 |
| — | VERTEX PHARMACEUTICALS INC | 1,315 | $861K | 0.1% | $654.75 | — | — | Call | 92532F900 |
| — | MICROBOT MED INC | 1,249,400 | $843K | 0.1% | $0.67 | $1.42 | — | COM | 59503A105 |
| — | GLYCOMIMETICS INC | 51,603 | $838K | 0.1% | $16.24 | $16.24 | — | COM | 38000Q102 |
| — | CELSION CORP | 369,860 | $828K | 0.1% | $2.24 | $2.24 | — | COM | 15117N503 |
| — | BIOGEN INC | 30 | $821K | 0.1% | $27366.67 | — | — | Call | 09062X903 |
| — | INTERPACE DIAGNOSTICS GROUP | 919,854 | $812K | 0.1% | $0.88 | $1.02 | — | COM | 46062X204 |
| — | AFFIMED INC | 425,463 | $787K | 0.1% | $1.85 | $1.85 | — | COM | N01045108 |
| — | MANNKIND CORP | 3,224 | $735K | 0.1% | $227.98 | — | — | Put | 56400P906 |
| — | APRICUS BIOSCIENCES INC | 1,800,000 | $731K | 0.1% | $0.41 | $0.41 | — | COM | 03832V307 |
| — | ACTINIUM PHARMACEUTICALS INC | 1,997,700 | $729K | 0.1% | $0.36 | $0.36 | — | COM | 00507W107 |
| — | HELIOS &MATHESON ANALYTICS INC | 249,294 | $706K | 0.1% | $2.83 | $2.83 | — | COM | 42327L200 |
| — | SUPERCONDUCTOR TECHNOLOGIES | 735,880 | $693K | 0.1% | $0.94 | $0.94 | — | COM | 867931503 |
| GALT | GALECTIN THERAPEUTICS INC | 143,400 | $680K | 0.1% | $4.74 | $4.66 | 0.0% | COM | 363225202 |
| — | MERCK & CO INC | 120 | $654K | 0.1% | $5450.00 | — | — | Put | 58933Y955 |
| — | APPLIED DNA SCIENCES INC | 454,381 | $654K | 0.1% | $1.44 | $1.59 | — | COM | 03815U201 |
| — | DBV TECHNOLOGIES SA | 258 | $595K | 0.1% | $2306.20 | — | — | Call | 23306J901 |
| — | HELIOS &MATHESON ANALYTICS INC | 2,054 | $581K | 0.1% | $282.86 | — | — | Put | 42327L950 |
| — | FUELCELL ENERGY INC | 3,297 | $570K | 0.1% | $172.88 | — | — | Put | 35952H952 |
| — | PULMATRIX INC | 1,087,507 | $554K | 0.1% | $0.51 | $0.51 | — | COM | 74584P103 |
| — | AURIS MEDICAL HOLDING AG | 342,989 | $549K | 0.1% | $1.60 | $1.60 | — | COM | H0381L104 |
| — | ADVERUM BIOTECHNOLOGIES INC | 944 | $548K | 0.1% | $580.51 | — | — | Call | 00773U908 |
| PRQR | PROQR THERAPEUTICS N V | 172,160 | $529K | 0.1% | $3.07 * | $3.59 | -10.4% | SHS | N71542109 |
| — | FIBROGEN INC | 113 | $522K | 0.1% | $4619.47 | — | — | Call | 31572Q908 |
| — | CHF SOLUTIONS INC | 180,498 | $504K | 0.1% | $2.79 | $2.99 | — | COM | 12542Q508 |
| MNKD | MANNKIND CORP | 201,908 | $460K | 0.1% | $2.28 * | $3.42 | -21.2% | COM | 56400P706 |
| — | TRANSENTERIX INC | 256,715 | $436K | 0.1% | $1.70 | $1.93 | — | COM | 89366M201 |
| — | SANGAMO THERAPEUTICS INC | 229 | $435K | 0.1% | $1899.56 | — | — | Call | 800677906 |
| — | PRECIPIO INC | 764,411 | $411K | 0.0% | $0.54 | $0.54 | — | COM | 74019L107 |
| — | NANOVIBRONIX INC | 85,791 | $408K | 0.0% | $4.76 | $4.68 | — | COM | 63008J108 |
| — | SENESTECH INC | 794,740 | $405K | 0.0% | $0.51 | $0.63 | — | COM | 81720R109 |
| — | INPIXON | 366,925 | $394K | 0.0% | $1.07 | $1.07 | — | COM | 45790J305 |
| ROSGQ | ROSETTA GENOMICS LTD | 934,608 | $383K | 0.0% | $0.41 * | $0.49 | 0.0% | SHS | M82183209 |
| — | SUNESIS PHARMACEUTICALS INC | 1,396 | $380K | 0.0% | $272.21 | — | — | Call | 867328900 |
| MRK | MERCK & CO INC | 6,864 | $374K | 0.0% | $54.49 * | $42.25 | 0.0% | COM | 58933Y105 |
| — | STRATA SKIN SCIENCES INC | 315,745 | $368K | 0.0% | $1.17 | $1.58 | — | COM | 86272A206 |
| — | BIOAMBER INC | 7,819,887 | $368K | 0.0% | $0.05 | $0.05 | — | COM | 09072Q106 |
| — | ACCELERON PHARMA INC | 8,646 | $338K | 0.0% | $39.09 | $39.09 | — | COM | 00434H108 |
| — | ONCONOVA THERAPEUTICS INC | 399,580 | $334K | 0.0% | $0.84 | $2.33 | — | COM | 68232V306 |
| — | AMARIN CORP PLC | 1,109 | $334K | 0.0% | $301.17 | — | — | Put | 023111956 |
| XENE | XENON PHARMACEUTICALS INC | 67,000 | $328K | 0.0% | $4.90 * | $7.35 | -49.7% | COM | 98420N105 |
| — | EIGER BIOPHARMACEUTICALS INC | 32,190 | $317K | 0.0% | $9.85 | $15.78 | — | COM | 28249U105 |
| INSM | INSMED INC | 13,300 | $300K | 0.0% | $22.56 * | $26.32 | 0.0% | COM | 457669307 |
| — | SONOMA PHARMACEUTICALS INC | 69,200 | $255K | 0.0% | $3.68 | $3.68 | — | COM | 83558L105 |
| — | INSPIREMD INC | 243,794 | $254K | 0.0% | $1.04 | $0.13 | — | COM | 45779A804 |
| — | EDAP TMS SA | 1,008 | $234K | 0.0% | $232.14 | — | — | Put | 268311957 |
| MNKD | MANNKIND CORP | 1,000 | $228K | 0.0% | $228.00 * | $3.42 | -21.2% | Call | 56400P706 |
| — | ACCELERON PHARMA INC | 55 | $215K | 0.0% | $3909.09 | — | — | Call | 00434H908 |
| AXSM | AXSOME THERAPEUTICS INC | 81,159 | $199K | 0.0% | $2.45 * | $2.99 | 0.0% | COM | 05464T104 |
| — | ONCONOVA THERAPEUTICS INC | 654,019 | $196K | 0.0% | $0.30 | $1.53 | — | *W | 68232V116 |
| — | SOLID BIOSCIENCES INC | 25,000 | $188K | 0.0% | $7.52 | $7.52 | — | COM | 83422E105 |
| — | ABEONA THERAPEUTICS INC | 12,998 | $187K | 0.0% | $14.39 | $14.39 | — | COM | 00289Y107 |
| — | IMMUNOGEN INC | 164 | $173K | 0.0% | $1054.88 | — | — | Put | 45253H951 |
| — | MARINUS PHARMACEUTICALS INC | 451 | $172K | 0.0% | $381.37 | — | — | Call | 56854Q901 |
| — | BIO PATH HOLDINGS INC | 85,013 | $170K | 0.0% | $2.00 | $0.20 | — | COM | 09057N102 |
| — | APPLIED DNA SCIENCES INC | 648,824 | $162K | 0.0% | $0.25 | $0.49 | — | *W | 03815U110 |
| — | FUELCELL ENERGY INC | 91,400 | $158K | 0.0% | $1.73 | $1.73 | — | COM | 35952H502 |
| — | SOPHIRIS BIO INC | 729 | $147K | 0.0% | $201.65 | — | — | Put | 83578Q959 |
| — | SIGMA LABS INC | 375,718 | $142K | 0.0% | $0.38 | $0.82 | — | *W | 826598112 |
| EDAP | EDAP TMS SA | 60,600 | $141K | 0.0% | $2.33 | $2.33 | — | ADR | 268311107 |
| — | VISTAGEN THERAPEUTICS INC | 143,486 | $133K | 0.0% | $0.93 | $1.11 | — | COM | 92840H202 |
| — | TRANSENTERIX INC | 728 | $124K | 0.0% | $170.33 | — | — | Put | 89366M951 |
| — | GALECTIN THERAPEUTICS INC | 210 | $100K | 0.0% | $476.19 | — | — | Put | 363225952 |
| — | RXI PHARMACEUTICALS CORP | 196,522 | $88,000 | 0.0% | $0.45 | $0.45 | — | *W | 74979C121 |
| — | VICAL INC. | 59,832 | $87,000 | 0.0% | $1.45 | $1.83 | — | COM | 925602203 |
| — | PTC THERAPEUTICS INC | 1,475 | $84,000 | 0.0% | $56.95 | — | — | Call | 69366J900 |
| — | PROTHENA CORPORATION PLC | 240 | $74,000 | 0.0% | $308.33 | — | — | Call | G72800908 |
| — | BRAINSTORM CELL THERAPEUTICS | 22,323 | $70,000 | 0.0% | $3.14 | $3.14 | — | COM | 10501E201 |
| — | AMARIN CORP PLC | 20,300 | $61,000 | 0.0% | $3.00 | $3.00 | — | ADR | 023111206 |
| — | SOPHIRIS BIO INC | 290 | $58,000 | 0.0% | $200.00 | — | — | Call | 83578Q909 |
| — | CHECK-CAP LTD | 75,280 | $39,000 | 0.0% | $0.52 | $1.93 | — | COM | M2361E112 |
| — | PLURISTEM THERAPEUTICS INC | 27,640 | $38,000 | 0.0% | $1.37 | $1.37 | — | COM | 72940R102 |
| VNRX | VOLITIONRX LTD | 13,167 | $32,000 | 0.0% | $2.43 * | $2.93 | 0.0% | COM | 928661107 |
| — | MEDIGUS LTD | 23,606 | $30,000 | 0.0% | $1.27 | $2.18 | — | ADR | 58471G201 |
| — | INSPIREMD INC | 1,998,417 | $30,000 | 0.0% | $0.02 | $0.08 | — | *W | 45779A135 |
| — | BIOCEPT INC | 92,374 | $27,000 | 0.0% | $0.29 | $0.69 | — | COM | 09072V204 |
| — | BENITEC BIOPHARMA LTD | 87,693 | $21,000 | 0.0% | $0.24 | $0.35 | — | Call | 082053117 |
| — | INSPIREMD INC | 911,373 | $18,000 | 0.0% | $0.02 | $0.60 | — | *W | 45779A127 |
| — | PLURISTEM THERAPEUTICS INC | 122 | $17,000 | 0.0% | $139.34 | — | — | Put | 72940R952 |
| — | CYTORI THERAPEUTICS INC | 520,858 | $14,000 | 0.0% | $0.03 | $0.76 | — | Call | 23283K121 |
| — | IMMUNOCELLULAR THERAPEUTICS | 225,187 | $7,000 | 0.0% | $0.03 | $0.48 | — | Call | 452536121 |
| — | SELLAS LIFE SCIENCES GROUP INC | 1,518 | $4,000 | 0.0% | $2.64 | — | — | Call | 81642T900 |
| — | VERSARTIS INC | 200 | $3,000 | 0.0% | $15.00 | — | — | Call | 92529L902 |
| HALO | HALOZYME THERAPEUTICS INC | 102 | $2,000 | 0.0% | $19.61 | $19.37 | 0.0% | COM | 40637H109 |
| — | AQUABOUNTY TECHNOLOGIES INC | 113 | $0 | 0.0% | $0.00 | — | — | COM | 03842K200 |