Location: Baltimore, MD
CIK: 0001595725 · Show all filings
Period: Q1 2024 (← Previous) (Next →)
Filing Date: May 15, 2024
Total Value: $3.939B (99.8% shares, 0.2% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| — | BLUEPRINT MEDICINES CORP | 2,498,448 | $237M | 6.0% | $63.00 | — | COM | 09627Y109 |
| IMCR | IMMUNOCORE HLDGS PLC | 2,367,816 | $154M | 3.9% | $42.88 | — | ADS | 45258D105 |
| NBIX | NEUROCRINE BIOSCIENCES INC | 1,054,900 | $145M | 3.7% | $78.19 | +74.7% | COM | 64125C109 |
| EVH | EVOLENT HEALTH INC | 3,987,500 | $131M | 3.3% | $25.06 | +27.3% | CL A | 30050B101 |
| ISRG | INTUITIVE SURGICAL INC | 298,500 | $119M | 3.0% | $264.69 | +42.8% | COM NEW | 46120E602 |
| UNH | UNITEDHEALTH GROUP INC | 230,000 | $114M | 2.9% | $219.29 | +123.0% | COM | 91324P102 |
| PEN | PENUMBRA INC | 505,000 | $113M | 2.9% | $179.03 | +38.1% | COM | 70975L107 |
| IDXX | IDEXX LABS INC | 179,250 | $96.78M | 2.5% | $335.38 | +62.9% | COM | 45168D104 |
| ACHC | ACADIA HEALTHCARE COMPANY IN | 1,177,500 | $93.28M | 2.4% | $57.08 | +43.3% | COM | 00404A109 |
| ARGX | ARGENX SE | 229,250 | $90.26M | 2.3% | $153.41 | — | SPONSORED ADR | 04016X101 |
| BSX | BOSTON SCIENTIFIC CORP | 1,232,500 | $84.41M | 2.1% | $52.45 | +22.6% | COM | 101137107 |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 1,774,938 | $82.87M | 2.1% | $59.75 | -21.0% | COM | 90400D108 |
| DXCM | DEXCOM INC | 596,750 | $82.77M | 2.1% | $97.36 | +29.1% | COM | 252131107 |
| LLY | ELI LILLY & CO | 103,250 | $80.32M | 2.0% | $616.74 | +13.9% | COM | 532457108 |
| FRPT | FRESHPET INC | 662,500 | $76.76M | 1.9% | $60.72 | +59.2% | COM | 358039105 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 285,931 | $76.36M | 1.9% | $108.20 | +117.8% | COM | 558868105 |
| EXAS | EXACT SCIENCES CORP | 1,059,750 | $73.19M | 1.9% | $54.51 | +16.0% | COM | 30063P105 |
| ALGN | ALIGN TECHNOLOGY INC | 220,000 | $72.14M | 1.8% | $312.87 | -6.2% | COM | 016255101 |
| RYTM | RHYTHM PHARMACEUTICALS INC | 1,522,893 | $65.99M | 1.7% | $15.80 | +177.0% | COM | 76243J105 |
| EW | EDWARDS LIFESCIENCES CORP | 647,300 | $61.86M | 1.6% | $62.58 | +34.2% | COM | 28176E108 |
| KYMR | KYMERA THERAPEUTICS INC | 1,522,238 | $61.19M | 1.6% | $30.84 | +16.0% | COM | 501575104 |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 1,372,185 | $57.59M | 1.5% | $33.14 | +23.9% | COM NEW | 15117B202 |
| PHR | PHREESIA INC | 2,365,000 | $56.59M | 1.4% | $26.02 | -4.5% | COM | 71944F106 |
| PODD | INSULET CORP | 320,000 | $54.85M | 1.4% | $183.83 | +1.4% | COM | 45784P101 |
| WST | WEST PHARMACEUTICAL SVSC INC | 137,250 | $54.31M | 1.4% | $294.97 | +24.7% | COM | 955306105 |
| XENE | XENON PHARMACEUTICALS INC | 1,255,577 | $54.05M | 1.4% | $23.42 | +96.4% | COM | 98420N105 |
| AGL | AGILON HEALTH INC | 8,835,000 | $53.89M | 1.4% | $32.03 | -79.2% | COM | 00857U107 |
| — | MERUS N V | 1,146,560 | $51.63M | 1.3% | $29.98 | — | COM | N5749R100 |
| AGIO | AGIOS PHARMACEUTICALS INC | 1,764,505 | $51.59M | 1.3% | $40.40 | -33.7% | COM | 00847X104 |
| HUM | HUMANA INC | 147,408 | $51.11M | 1.3% | $373.18 | -0.9% | COM | 444859102 |
| MIRM | MIRUM PHARMACEUTICALS INC | 1,856,564 | $46.64M | 1.2% | $14.67 | +87.5% | COM | 604749101 |
| IRTC | IRHYTHM TECHNOLOGIES INC | 392,250 | $45.5M | 1.2% | $74.00 | +51.9% | COM | 450056106 |
| — | SHOCKWAVE MED INC | 135,000 | $43.96M | 1.1% | $130.41 | — | COM | 82489T104 |
| ASND | ASCENDIS PHARMA A/S | 290,000 | $43.84M | 1.1% | $85.24 | — | SPONSORED ADR | 04351P101 |
| SRPT | SAREPTA THERAPEUTICS INC | 327,600 | $42.41M | 1.1% | $62.74 | +95.3% | COM | 803607100 |
| AZTA | AZENTA INC | 694,750 | $41.88M | 1.1% | $61.73 | +3.7% | COM | 114340102 |
| — | OLINK HLDG AB | 1,676,500 | $39.41M | 1.0% | $22.11 | — | SPONSORED ADS | 680710100 |
| IMVT | IMMUNOVANT INC | 1,150,123 | $37.16M | 0.9% | $28.80 | +26.7% | COM | 45258J102 |
| — | ACCOLADE INC | 3,540,000 | $37.1M | 0.9% | $19.76 | — | COM | 00437E102 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 244,000 | $36.47M | 0.9% | $102.35 | +63.0% | COM | 02043Q107 |
| — | AKERO THERAPEUTICS INC | 1,299,888 | $32.84M | 0.8% | $29.55 | — | COM | 00973Y108 |
| OSCR | OSCAR HEALTH INC | 2,110,000 | $31.38M | 0.8% | $11.33 | +20.9% | CL A | 687793109 |
| PCRX | PACIRA BIOSCIENCES INC | 1,055,500 | $30.84M | 0.8% | $48.41 | -36.5% | COM | 695127100 |
| RVMD | REVOLUTION MEDICINES INC | 923,681 | $29.77M | 0.8% | $25.82 | +14.8% | COM | 76155X100 |
| LFST | LIFESTANCE HEALTH GROUP INC | 4,780,000 | $29.49M | 0.7% | $13.69 | -50.8% | COM | 53228F101 |
| SGRY | SURGERY PARTNERS INC | 985,000 | $29.38M | 0.7% | $31.29 | 0.0% | COM | 86881A100 |
| WRBY | WARBY PARKER INC | 2,080,000 | $28.31M | 0.7% | $29.52 | -55.0% | CL A COM | 93403J106 |
| — | INOZYME PHARMA INC | 3,681,174 | $28.2M | 0.7% | $9.28 | — | COM | 45790W108 |
| INSP | INSPIRE MED SYS INC | 130,500 | $28.03M | 0.7% | $200.97 | -2.5% | COM | 457730109 |
| LEGN | LEGEND BIOTECH CORP | 499,486 | $28.02M | 0.7% | $41.79 | — | SPONSORED ADS | 52490G102 |
| MREO | MEREO BIOPHARMA GROUP PLC | 8,142,109 | $26.87M | 0.7% | $2.59 | — | SPON ADS | 589492107 |
| TVTX | TRAVERE THERAPEUTICS INC | 3,424,818 | $26.41M | 0.7% | $15.00 | -43.8% | COM | 89422G107 |
| — | CEREVEL THERAPEUTICS HLDNG I | 547,946 | $23.16M | 0.6% | $25.08 | — | COM | 15678U128 |
| IRON | DISC MEDICINE INC | 363,468 | $22.63M | 0.6% | $47.82 | +35.6% | COM | 254604101 |
| COLL | COLLEGIUM PHARMACEUTICAL INC | 562,000 | $21.82M | 0.6% | $15.97 | +119.1% | COM | 19459J104 |
| VKTX | VIKING THERAPEUTICS INC | 261,000 | $21.4M | 0.5% | $44.50 | 0.0% | COM | 92686J106 |
| — | DYNAVAX TECHNOLOGIES CORP | 1,675,474 | $20.79M | 0.5% | $7.97 | — | COM NEW | 268158201 |
| ZLAB | ZAI LAB LTD | 1,297,123 | $20.78M | 0.5% | $51.72 | — | ADR | 98887Q104 |
| MGNX | MACROGENICS INC | 1,305,250 | $19.21M | 0.5% | $16.70 | -9.5% | COM | 556099109 |
| NVO | NOVO-NORDISK A S | 147,500 | $18.94M | 0.5% | $128.40 | — | ADR | 670100205 |
| KRYS | KRYSTAL BIOTECH INC | 103,969 | $18.5M | 0.5% | $113.89 | +22.0% | COM | 501147102 |
| BCRX | BIOCRYST PHARMACEUTICALS INC | 3,496,256 | $17.76M | 0.5% | $9.13 | -38.4% | COM | 09058V103 |
| GPCR | STRUCTURE THERAPEUTICS INC | 412,649 | $17.69M | 0.4% | $41.40 | — | SPONSORED ADS | 86366E106 |
| PHVS | PHARVARIS N V | 752,924 | $17.4M | 0.4% | $26.56 | 0.0% | COM | N69605108 |
| PRTA | PROTHENA CORP PLC | 625,048 | $15.48M | 0.4% | $17.63 | +68.7% | SHS | G72800108 |
| — | NEVRO CORP | 1,065,000 | $15.38M | 0.4% | $72.87 | — | COM | 64157F103 |
| VERA | VERA THERAPEUTICS INC | 341,168 | $14.71M | 0.4% | $35.64 | 0.0% | CL A | 92337R101 |
| — | MERSANA THERAPEUTICS INC | 3,046,782 | $13.65M | 0.3% | $13.04 | — | COM | 59045L106 |
| FOLD | AMICUS THERAPEUTICS INC | 1,152,656 | $13.58M | 0.3% | $11.58 | +10.4% | COM | 03152W109 |
| CRNX | CRINETICS PHARMACEUTICALS IN | 289,400 | $13.55M | 0.3% | $39.13 | 0.0% | COM | 22663K107 |
| CRL | CHARLES RIV LABS INTL INC | 48,500 | $13.14M | 0.3% | $238.81 | 0.0% | COM | 159864107 |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 148,832 | $13M | 0.3% | $85.70 | +4.5% | COM | 09061G101 |
| DYN | DYNE THERAPEUTICS INC | 451,824 | $12.83M | 0.3% | $22.62 | 0.0% | COM | 26818M108 |
| JSPR | JASPER THERAPEUTICS INC | 404,335 | $11.87M | 0.3% | $17.76 | 0.0% | COM NEW | 471871202 |
| CMPX | COMPASS THERAPEUTICS INC | 5,513,788 | $10.92M | 0.3% | $3.31 | -47.8% | COM | 20454B104 |
| EDAP | EDAP TMS S A | 1,475,000 | $10.84M | 0.3% | $7.60 | — | SPONSORED ADR | 268311107 |
| MLYS | MINERALYS THERAPEUTICS INC | 792,615 | $10.23M | 0.3% | $16.83 | -26.6% | COM | 603170101 |
| — | APPLIED THERAPEUTICS INC | 1,497,918 | $10.19M | 0.3% | $15.72 | — | COM | 03828A101 |
| NUVL | NUVALENT INC | 125,302 | $9.409M | 0.2% | $79.58 | 0.0% | COM | 670703107 |
| ABOS | ACUMEN PHARMACEUTICALS INC | 2,300,059 | $9.315M | 0.2% | $6.18 | -39.0% | COM | 00509G209 |
| IMTX | IMMATICS N.V | 848,751 | $8.92M | 0.2% | $9.14 | +27.5% | SHS | N44445109 |
| NMRA | NEUMORA THERAPEUTICS INC. | 646,118 | $8.884M | 0.2% | $16.17 | 0.0% | COM | 640979100 |
| ELVN | ENLIVEN THERAPEUTICS INC | 428,571 | $7.539M | 0.2% | $15.34 | 0.0% | COM | 29337E102 |
| CGON | CG ONCOLOGY INC | 170,859 | $7.501M | 0.2% | $40.84 | 0.0% | COM | 156944100 |
| BHVN | BIOHAVEN LTD | 126,984 | $6.945M | 0.2% | $49.52 | 0.0% | COM | G1110E107 |
| FULC | FULCRUM THERAPEUTICS INC | 727,673 | $6.869M | 0.2% | $14.24 | -37.3% | COM | 359616109 |
| AUTL | AUTOLUS THERAPEUTICS PLC | 1,032,988 | $6.59M | 0.2% | $6.38 | — | SPON ADS | 05280R100 |
| LUNG | PULMONX CORP | 652,400 | $6.048M | 0.2% | $45.31 | -74.1% | COM | 745848101 |
| AUPH | AURINIA PHARMACEUTICALS INC | 1,150,347 | $5.763M | 0.1% | $9.11 | -25.5% | COM | 05156V102 |
| — | ESSA PHARMA INC | 677,005 | $5.748M | 0.1% | $22.67 | — | COM NEW | 29668H708 |
| PLRX | PLIANT THERAPEUTICS INC | 384,996 | $5.736M | 0.1% | $28.47 | -42.1% | COM | 729139105 |
| BEAM | BEAM THERAPEUTICS INC | 147,510 | $4.874M | 0.1% | $37.65 | -17.2% | COM | 07373V105 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 32,500 | $4.857M | 0.1% | $102.35 | +63.0% | Call | 02043Q107 |
| — | VINCERX PHARMA INC | 891,719 | $4.512M | 0.1% | $12.19 | — | COM NEW | 92731L106 |
| KYTX | KYVERNA THERAPEUTICS INC | 178,963 | $4.445M | 0.1% | $27.84 | 0.0% | COM | 501976104 |
| SGMT | SAGIMET BIOSCIENCES INC | 770,671 | $4.177M | 0.1% | $13.06 | -45.0% | COM SER A | 786700104 |
| GOSS | GOSSAMER BIO INC | 3,266,960 | $3.855M | 0.1% | $2.62 | -57.9% | COM | 38341P102 |
| — | GOSSAMER BIO INC | 9,573,000 | $3.845M | 0.1% | $1.01 | — | NOTE 5.000% 6/0 | 38341PAA0 |
| ADAPY | ADAPTIMMUNE THERAPEUTICS PLC | 2,425,468 | $3.832M | 0.1% | $7.10 | — | SPONDS ADR | 00653A107 |
| ACRS | ACLARIS THERAPEUTICS INC | 2,753,495 | $3.414M | 0.1% | $10.84 | -89.0% | COM | 00461U105 |
| CGEN | COMPUGEN LTD | 1,289,990 | $3.328M | 0.1% | $6.12 | -62.0% | ORD | M25722105 |
| AMLX | AMYLYX PHARMACEUTICALS INC | 1,011,412 | $2.872M | 0.1% | $22.81 | -42.7% | COM | 03237H101 |
| — | TRAVERE THERAPEUTICS INC | 3,250,000 | $2.842M | 0.1% | $0.79 | — | NOTE 2.500% 9/1 | 761299AB2 |
| BMEA | BIOMEA FUSION INC | 181,147 | $2.708M | 0.1% | $15.37 | +7.1% | COM | 09077A106 |
| NVAX | NOVAVAX INC | 537,625 | $2.57M | 0.1% | $37.34 | -87.6% | COM NEW | 670002401 |
| CYPH | LEAP THERAPEUTICS INC | 911,937 | $2.426M | 0.1% | $4.84 | -38.1% | COM NEW | 52187K200 |
| — | SPRUCE BIOSCIENCES INC | 2,609,125 | $2.051M | 0.1% | $15.23 | — | COM | 85209E109 |
| — | NEUROCRINE BIOSCIENCES INC | 1,000,000 | $1.807M | 0.0% | $1.45 | — | NOTE 2.250% 5/1 | 64125CAD1 |
| — | VIGIL NEUROSCIENCE INC | 471,958 | $1.609M | 0.0% | $7.03 | — | COM | 92673K108 |
| XLO | XILIO THERAPEUTICS INC | 1,440,759 | $1.556M | 0.0% | $14.70 | -95.3% | COM | 98422T100 |
| — | RENEO PHARMACEUTICALS INC | 751,730 | $1.248M | 0.0% | $9.31 | — | COM | 75974E103 |
| — | NEVRO CORP | 500,000 | $474K | 0.0% | $1.37 | — | NOTE 2.750% 4/0 | 64157FAC7 |
| TLPH | TALPHERA INC | 316,460 | $326K | 0.0% | $2.81 | -62.0% | COM NEW | 00444T209 |
| — | NUVATION BIO INC | 134,028 | $40,543 | 0.0% | $2.67 | — | *W EXP 07/07/202 | 67080N119 |