TCG Crossover Management, LLC Diversified Active

Location: Palo Alto, CA

CIK: 0001839948 · Show all filings

Period: Q1 2025 (← Previous) (Next →)

Filing Date: May 14, 2025

Total Value: $733M (100.0% shares, 0.0% debt)

Holdings (37)

CGON CG ONCOLOGY INC 12.3%

Value $89.88M Shares 3,670,206 Share Price $24.49 * Est. Cost/Share $40.67 Unrealized @ Report Date -30.8%

COGT COGENT BIOSCIENCES INC 5.7%

Value $41.72M Shares 6,964,375 Share Price $5.99 * Est. Cost/Share $9.05 Unrealized @ Report Date -13.4%

CNTA CENTESSA PHARMACEUTICALS PLC 5.7%

Value $41.57M Shares 2,890,816 Share Price $14.38 Est. Cost/Share $7.22 Unrealized @ Report Date —

MLYS MINERALYS THERAPEUTICS INC 5.4%

Value $39.23M Shares 2,470,265 Share Price $15.88 * Est. Cost/Share $12.35 Unrealized @ Report Date -6.9%

OCUL OCULAR THERAPEUTIX INC 5.3%

Value $38.99M Shares 5,319,148 Share Price $7.33 * Est. Cost/Share $7.10 Unrealized @ Report Date +8.3%

ABVX ABIVAX SA AMERICAN DEPOSITARY SHARES 5.2%

Value $37.85M Shares 6,056,596 Share Price $6.25 Est. Cost/Share $12.76 Unrealized @ Report Date —

SVRA SAVARA INC 4.7%

Value $34.24M Shares 12,362,205 Share Price $2.77 Est. Cost/Share $3.73 Unrealized @ Report Date -26.0%

DYN DYNE THERAPEUTICS INC 3.8%

Value $27.72M Shares 2,650,150 Share Price $10.46 * Est. Cost/Share $16.62 Unrealized @ Report Date -13.9%

DNTH DIANTHUS THERAPEUTICS INC 3.7%

Value $27.24M Shares 1,501,624 Share Price $18.14 * Est. Cost/Share $25.71 Unrealized @ Report Date -14.3%

TYRA TYRA BIOSCIENCES INC 3.7%

Value $26.95M Shares 2,898,103 Share Price $9.30 * Est. Cost/Share $12.78 Unrealized @ Report Date +1.3%

XNCR XENCOR INC 3.6%

Value $26.09M Shares 2,452,138 Share Price $10.64 * Est. Cost/Share $18.82 Unrealized @ Report Date -12.2%

IRON DISC MEDICINE INC 3.2%

Value $23.1M Shares 465,257 Share Price $49.64 * Est. Cost/Share $33.98 Unrealized @ Report Date +63.6%

— TOURMALINE BIO INC 3.1%

Value $22.47M Shares 1,477,593 Share Price $15.21 Est. Cost/Share $25.14 Unrealized @ Report Date —

— CIDARA THERAPEUTICS INC 3.0%

Value $21.67M Shares 1,005,901 Share Price $21.54 Est. Cost/Share $25.94 Unrealized @ Report Date —

AMLX AMYLYX PHARMACEUTICALS INC 2.9%

Value $21.04M Shares 5,943,812 Share Price $3.54 Est. Cost/Share $2.53 Unrealized @ Report Date +40.4%

SLNO SOLENO THERAPEUTICS INC 2.7%

Value $19.65M Shares 275,000 Share Price $71.45 * Est. Cost/Share $47.87 Unrealized @ Report Date +1.7%

EYPT EYEPOINT PHARMACEUTICALS INC 2.6%

Value $19.36M Shares 3,572,335 Share Price $5.42 * Est. Cost/Share $10.51 Unrealized @ Report Date -33.4%

GPCR STRUCTURE THERAPEUTICS INC 2.5%

Value $18.4M Shares 1,063,000 Share Price $17.31 Est. Cost/Share $43.45 Unrealized @ Report Date —

UPB UPSTREAM BIO INC 2.3%

Value $17.15M Shares 2,801,763 Share Price $6.12 * Est. Cost/Share $22.33 Unrealized @ Report Date -57.2%

— RAPT Therapeutics, Inc. 2.2%

Value $15.97M Shares 13,090,200 Share Price $1.22 Est. Cost/Share $1.50 Unrealized @ Report Date —

FULC FULCRUM THERAPEUTICS INC 2.1%

Value $15.12M Shares 5,250,000 Share Price $2.88 * Est. Cost/Share $7.42 Unrealized @ Report Date -50.5%

— ASTRIA THERAPEUTICS INC 2.0%

Value $14.75M Shares 2,761,861 Share Price $5.34 Est. Cost/Share $14.07 Unrealized @ Report Date —

TNGX TANGO THERAPEUTICS INC 2.0%

Value $14.71M Shares 10,736,000 Share Price $1.37 * Est. Cost/Share $4.64 Unrealized @ Report Date -47.1%

CMPS COMPASS PATHWAYS LTD 1.5%

Value $11.03M Shares 3,858,000 Share Price $2.86 Est. Cost/Share $7.40 Unrealized @ Report Date —

KURA KURA ONCOLOGY INC 1.3%

Value $9.396M Shares 1,423,642 Share Price $6.60 * Est. Cost/Share $14.54 Unrealized @ Report Date -46.4%

— THIRD HARMONIC BIO INC 1.2%

Value $8.694M Shares 2,505,424 Share Price $3.47 Est. Cost/Share $13.43 Unrealized @ Report Date —

SLN SILENCE THERAPEUTICS PLC 1.2%

Value $8.555M Shares 3,033,560 Share Price $2.82 Est. Cost/Share $14.21 Unrealized @ Report Date —

— ADVERUM BIOTECHNOLOGIES INC 1.1%

Value $7.851M Shares 1,796,482 Share Price $4.37 Est. Cost/Share $7.02 Unrealized @ Report Date —

VTGN VISTAGEN THERAPEUTICS INC 0.9%

Value $6.691M Shares 2,676,580 Share Price $2.50 * Est. Cost/Share $3.41 Unrealized @ Report Date -17.1%

— AEROVATE THERAPEUTICS INC 0.8%

Value $5.624M Shares 2,240,809 Share Price $2.51 Est. Cost/Share $15.50 Unrealized @ Report Date —

TRDA ENTRADA THERAPEUTICS INC 0.7%

Value $5.288M Shares 584,955 Share Price $9.04 Est. Cost/Share $17.12 Unrealized @ Report Date —

MBX MBX BIOSCIENCES INC 0.7%

Value $4.797M Shares 650,000 Share Price $7.38 * Est. Cost/Share $22.87 Unrealized @ Report Date -53.8%

AVTX AVALO THERAPEUTICS INC 0.5%

Value $3.869M Shares 483,000 Share Price $8.01 * Est. Cost/Share $10.31 Unrealized @ Report Date -26.5%

KOD KODIAK SCIENCES INC 0.4%

Value $3.213M Shares 1,145,538 Share Price $2.80 * Est. Cost/Share $4.16 Unrealized @ Report Date +30.6%

— NEKTAR THERAPEUTICS 0.4%

Value $2.72M Shares 4,000,000 Share Price $0.68 Est. Cost/Share $0.93 Unrealized @ Report Date —

VTYX VENTYX BIOSCIENCES INC 0.0%

Value $364K Shares 316,195 Share Price $1.15 * Est. Cost/Share $29.94 Unrealized @ Report Date -94.3%

CABA CABALETTA BIO INC 0.0%

Value $120K Shares 86,795 Share Price $1.38 * Est. Cost/Share $3.64 Unrealized @ Report Date -41.5%

Ticker	Issuer	Shares	Value	%	Share Price	Est. Cost/Share	Unrealized @ Report Date	Class	CUSIP
CGON	CG ONCOLOGY INC	3,670,206	$89.88M	12.3%	$24.49 *	$40.67	-30.8%	COMM	156944100
COGT	COGENT BIOSCIENCES INC	6,964,375	$41.72M	5.7%	$5.99 *	$9.05	-13.4%	COMM	19240Q201
CNTA	CENTESSA PHARMACEUTICALS PLC	2,890,816	$41.57M	5.7%	$14.38	$7.22	—	ADRS	152309100
MLYS	MINERALYS THERAPEUTICS INC	2,470,265	$39.23M	5.4%	$15.88 *	$12.35	-6.9%	COMM	603170101
OCUL	OCULAR THERAPEUTIX INC	5,319,148	$38.99M	5.3%	$7.33 *	$7.10	+8.3%	COMM	67576A100
ABVX	ABIVAX SA AMERICAN DEPOSITARY SHARES	6,056,596	$37.85M	5.2%	$6.25	$12.76	—	ADRS	00370M103
SVRA	SAVARA INC	12,362,205	$34.24M	4.7%	$2.77	$3.73	-26.0%	COMM	805111101
DYN	DYNE THERAPEUTICS INC	2,650,150	$27.72M	3.8%	$10.46 *	$16.62	-13.9%	COMM	26818M108
DNTH	DIANTHUS THERAPEUTICS INC	1,501,624	$27.24M	3.7%	$18.14 *	$25.71	-14.3%	COMM	252828108
TYRA	TYRA BIOSCIENCES INC	2,898,103	$26.95M	3.7%	$9.30 *	$12.78	+1.3%	COMM	90240B106
XNCR	XENCOR INC	2,452,138	$26.09M	3.6%	$10.64 *	$18.82	-12.2%	COMM	98401F105
IRON	DISC MEDICINE INC	465,257	$23.1M	3.2%	$49.64 *	$33.98	+63.6%	COMM	254604101
—	TOURMALINE BIO INC	1,477,593	$22.47M	3.1%	$15.21	$25.14	—	COMM	89157D105
—	CIDARA THERAPEUTICS INC	1,005,901	$21.67M	3.0%	$21.54	$25.94	—	COMM	171757206
AMLX	AMYLYX PHARMACEUTICALS INC	5,943,812	$21.04M	2.9%	$3.54	$2.53	+40.4%	COMM	03237H101
SLNO	SOLENO THERAPEUTICS INC	275,000	$19.65M	2.7%	$71.45 *	$47.87	+1.7%	COMM	834203309
EYPT	EYEPOINT PHARMACEUTICALS INC	3,572,335	$19.36M	2.6%	$5.42 *	$10.51	-33.4%	COMM	30233G209
GPCR	STRUCTURE THERAPEUTICS INC	1,063,000	$18.4M	2.5%	$17.31	$43.45	—	ADRS	86366E106
UPB	UPSTREAM BIO INC	2,801,763	$17.15M	2.3%	$6.12 *	$22.33	-57.2%	COMM	91678A107
—	RAPT Therapeutics, Inc.	13,090,200	$15.97M	2.2%	$1.22	$1.50	—	COMM	75382E109
FULC	FULCRUM THERAPEUTICS INC	5,250,000	$15.12M	2.1%	$2.88 *	$7.42	-50.5%	COMM	359616109
—	ASTRIA THERAPEUTICS INC	2,761,861	$14.75M	2.0%	$5.34	$14.07	—	COMM	04635X102
TNGX	TANGO THERAPEUTICS INC	10,736,000	$14.71M	2.0%	$1.37 *	$4.64	-47.1%	COMM	87583X109
CMPS	COMPASS PATHWAYS LTD	3,858,000	$11.03M	1.5%	$2.86	$7.40	—	ADRS	20451W101
KURA	KURA ONCOLOGY INC	1,423,642	$9.396M	1.3%	$6.60 *	$14.54	-46.4%	COMM	50127T109
—	THIRD HARMONIC BIO INC	2,505,424	$8.694M	1.2%	$3.47	$13.43	—	COMM	88427A107
SLN	SILENCE THERAPEUTICS PLC	3,033,560	$8.555M	1.2%	$2.82	$14.21	—	ADRS	82686Q101
—	ADVERUM BIOTECHNOLOGIES INC	1,796,482	$7.851M	1.1%	$4.37	$7.02	—	COMM	00773U207
VTGN	VISTAGEN THERAPEUTICS INC	2,676,580	$6.691M	0.9%	$2.50 *	$3.41	-17.1%	COMM	92840H400
—	AEROVATE THERAPEUTICS INC	2,240,809	$5.624M	0.8%	$2.51	$15.50	—	COMM	008064107
TRDA	ENTRADA THERAPEUTICS INC	584,955	$5.288M	0.7%	$9.04	$17.12	—	COMM	29384C108
MBX	MBX BIOSCIENCES INC	650,000	$4.797M	0.7%	$7.38 *	$22.87	-53.8%	COMM	55287L101
AVTX	AVALO THERAPEUTICS INC	483,000	$3.869M	0.5%	$8.01 *	$10.31	-26.5%	COMM	05338F306
KOD	KODIAK SCIENCES INC	1,145,538	$3.213M	0.4%	$2.80 *	$4.16	+30.6%	COMM	50015M109
—	NEKTAR THERAPEUTICS	4,000,000	$2.72M	0.4%	$0.68	$0.93	—	COMM	640268108
VTYX	VENTYX BIOSCIENCES INC	316,195	$364K	0.0%	$1.15 *	$29.94	-94.3%	COMM	92332V107
CABA	CABALETTA BIO INC	86,795	$120K	0.0%	$1.38 *	$3.64	-41.5%	COMM	12674W109