TCG Crossover Management, LLC Diversified Active

Location: Palo Alto, CA

CIK: 0001839948 · Show all filings

Period: Q4 2025 (← Previous) (Next →)

Filing Date: Feb 17, 2026

Total Value: $3.022B (100.0% shares, 0.0% debt)

Holdings (43)

ABVX ABIVAX SA AMERICAN DEPOSITARY SHARES 31.7%

Value $959M Shares 7,111,596 Est. Cost $23.46 Unrealized —

COGT COGENT BIOSCIENCES INC 6.9%

Value $208M Shares 5,868,162 Est. Cost $9.05 Unrealized +210.6%

CGON CG ONCOLOGY INC 5.0%

Value $152M Shares 3,670,206 Est. Cost $40.67 Unrealized +1.7%

TNGX TANGO THERAPEUTICS INC 3.7%

Value $113M Shares 12,762,094 Est. Cost $5.96 Unrealized +44.6%

CNTA CENTESSA PHARMACEUTICALS PLC 3.5%

Value $107M Shares 4,286,480 Est. Cost $12.97 Unrealized —

DYN DYNE THERAPEUTICS INC 3.0%

Value $90.27M Shares 4,615,144 Est. Cost $14.30 Unrealized +32.4%

RAPT RAPT THERAPEUTICS INC 2.9%

Value $87.47M Shares 2,582,408 Est. Cost $16.21 Unrealized +91.6%

TYRA TYRA BIOSCIENCES INC 2.5%

Value $76.19M Shares 2,898,103 Est. Cost $12.78 Unrealized +43.7%

AMLX AMYLYX PHARMACEUTICALS INC 2.5%

Value $75.43M Shares 6,243,812 Est. Cost $2.86 Unrealized +374.1%

SVRA SAVARA INC 2.5%

Value $74.54M Shares 12,362,205 Est. Cost $3.73 Unrealized +31.2%

GLUE MONTE ROSA THERAPEUTICS INC 2.4%

Value $72.48M Shares 4,622,151 Est. Cost $13.48 Unrealized 0.0%

OCUL OCULAR THERAPEUTIX INC 2.3%

Value $69.69M Shares 5,740,231 Est. Cost $7.73 Unrealized +57.1%

DNTH DIANTHUS THERAPEUTICS INC 2.3%

Value $69.09M Shares 1,676,624 Est. Cost $25.70 Unrealized +50.9%

EYPT EYEPOINT PHARMACEUTICALS INC 2.2%

Value $65.27M Shares 3,572,335 Est. Cost $10.51 Unrealized +34.8%

GPCR STRUCTURE THERAPEUTICS INC 2.1%

Value $64.05M Shares 920,857 Est. Cost $43.45 Unrealized —

SYRE SPYRE THERAPEUTICS INC 2.1%

Value $62.26M Shares 1,900,582 Est. Cost $20.44 Unrealized +27.8%

FULC FULCRUM THERAPEUTICS INC 2.0%

Value $59.38M Shares 5,250,000 Est. Cost $7.42 Unrealized +37.2%

LQDA LIQUIDIA TECHNOLOGIES INC 2.0%

Value $58.98M Shares 1,710,084 Est. Cost $21.69 Unrealized +31.2%

BHVN BIOHAVEN LTD 1.7%

Value $52.29M Shares 4,631,317 Est. Cost $12.39 Unrealized 0.0%

IMVT IMMUNOVANT INC 1.4%

Value $42.22M Shares 1,660,933 Est. Cost $22.30 Unrealized 0.0%

KOD KODIAK SCIENCES INC 1.3%

Value $40.42M Shares 1,445,538 Est. Cost $7.55 Unrealized +171.3%

ADCT ADC THERAPEUTICS SA 1.3%

Value $40.21M Shares 11,390,175 Est. Cost $3.95 Unrealized +2.8%

LBRX LB PHARMACEUTICALS INC 1.3%

Value $38.84M Shares 1,745,015 Est. Cost $15.87 Unrealized +10.1%

XNCR XENCOR INC 1.2%

Value $37.54M Shares 2,452,138 Est. Cost $18.82 Unrealized -20.6%

RVMD REVOLUTION MEDICINES INC 1.2%

Value $34.77M Shares 436,473 Est. Cost $39.15 Unrealized +67.5%

AGIO AGIOS PHARMACEUTICALS INC 1.1%

Value $32.17M Shares 1,181,841 Est. Cost $34.05 Unrealized +3.0%

ARVN ARVINAS HOLDING CO LLC 1.0%

Value $31.62M Shares 2,666,216 Est. Cost $8.90 Unrealized +22.7%

RLAY RELAY THERAPEUTICS INC 0.9%

Value $27.24M Shares 3,220,186 Est. Cost $5.27 Unrealized +35.5%

JANX JANUX THERAPEUTICS INC 0.8%

Value $24.7M Shares 1,789,617 Est. Cost $23.52 Unrealized 0.0%

TRDA ENTRADA THERAPEUTICS INC 0.7%

Value $21.47M Shares 2,088,392 Est. Cost $12.20 Unrealized —

MBX MBX BIOSCIENCES INC 0.7%

Value $20.5M Shares 650,000 Est. Cost $22.87 Unrealized +6.1%

UPB UPSTREAM BIO INC 0.7%

Value $20.2M Shares 743,886 Est. Cost $22.33 Unrealized +11.5%

SLN SILENCE THERAPEUTICS PLC 0.6%

Value $18.44M Shares 3,033,560 Est. Cost $14.21 Unrealized —

URGN UROGEN PHARMA LTD 0.6%

Value $16.8M Shares 717,347 Est. Cost $17.96 Unrealized +20.8%

ALEC ALECTOR INC 0.5%

Value $15.6M Shares 10,000,000 Est. Cost $1.77 Unrealized 0.0%

MNPR MONOPAR THERAPEUTICS INC 0.3%

Value $9.267M Shares 141,915 Est. Cost $44.70 Unrealized +82.8%

AVTX AVALO THERAPEUTICS INC 0.3%

Value $8.771M Shares 483,000 Est. Cost $10.31 Unrealized +63.7%

MAZE MAZE THERAPEUTICS INC 0.2%

Value $7.201M Shares 173,816 Est. Cost $34.37 Unrealized 0.0%

MIRM MIRUM PHARMACEUTICALS INC 0.2%

Value $4.901M Shares 62,049 Est. Cost $71.78 Unrealized 0.0%

LONA Athira Pharma, Inc. 0.1%

Value $3.349M Shares 464,398 Est. Cost $4.58 Unrealized 0.0%

KRRO KORRO BIO INC 0.1%

Value $3.335M Shares 416,301 Est. Cost $22.19 Unrealized +5.3%

VTYX VENTYX BIOSCIENCES INC 0.1%

Value $2.855M Shares 316,195 Est. Cost $29.94 Unrealized -75.0%

VTGN VISTAGEN THERAPEUTICS INC 0.1%

Value $1.772M Shares 2,676,580 Est. Cost $3.41 Unrealized +5.9%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
ABVX	ABIVAX SA AMERICAN DEPOSITARY SHARES	7,111,596	$959M	31.7%	$23.46	—	ADRS	00370M103
COGT	COGENT BIOSCIENCES INC	5,868,162	$208M	6.9%	$9.05	+210.6%	COMM	19240Q201
CGON	CG ONCOLOGY INC	3,670,206	$152M	5.0%	$40.67	+1.7%	COMM	156944100
TNGX	TANGO THERAPEUTICS INC	12,762,094	$113M	3.7%	$5.96	+44.6%	COMM	87583X109
CNTA	CENTESSA PHARMACEUTICALS PLC	4,286,480	$107M	3.5%	$12.97	—	ADRS	152309100
DYN	DYNE THERAPEUTICS INC	4,615,144	$90.27M	3.0%	$14.30	+32.4%	COMM	26818M108
RAPT	RAPT THERAPEUTICS INC	2,582,408	$87.47M	2.9%	$16.21	+91.6%	COMM	75382E208
TYRA	TYRA BIOSCIENCES INC	2,898,103	$76.19M	2.5%	$12.78	+43.7%	COMM	90240B106
AMLX	AMYLYX PHARMACEUTICALS INC	6,243,812	$75.43M	2.5%	$2.86	+374.1%	COMM	03237H101
SVRA	SAVARA INC	12,362,205	$74.54M	2.5%	$3.73	+31.2%	COMM	805111101
GLUE	MONTE ROSA THERAPEUTICS INC	4,622,151	$72.48M	2.4%	$13.48	0.0%	COMM	61225M102
OCUL	OCULAR THERAPEUTIX INC	5,740,231	$69.69M	2.3%	$7.73	+57.1%	COMM	67576A100
DNTH	DIANTHUS THERAPEUTICS INC	1,676,624	$69.09M	2.3%	$25.70	+50.9%	COMM	252828108
EYPT	EYEPOINT PHARMACEUTICALS INC	3,572,335	$65.27M	2.2%	$10.51	+34.8%	COMM	30233G209
GPCR	STRUCTURE THERAPEUTICS INC	920,857	$64.05M	2.1%	$43.45	—	ADRS	86366E106
SYRE	SPYRE THERAPEUTICS INC	1,900,582	$62.26M	2.1%	$20.44	+27.8%	COMM	00773J202
FULC	FULCRUM THERAPEUTICS INC	5,250,000	$59.38M	2.0%	$7.42	+37.2%	COMM	359616109
LQDA	LIQUIDIA TECHNOLOGIES INC	1,710,084	$58.98M	2.0%	$21.69	+31.2%	COMM	53635D202
BHVN	BIOHAVEN LTD	4,631,317	$52.29M	1.7%	$12.39	0.0%	COMM	G1110E107
IMVT	IMMUNOVANT INC	1,660,933	$42.22M	1.4%	$22.30	0.0%	COMM	45258J102
KOD	KODIAK SCIENCES INC	1,445,538	$40.42M	1.3%	$7.55	+171.3%	COMM	50015M109
ADCT	ADC THERAPEUTICS SA	11,390,175	$40.21M	1.3%	$3.95	+2.8%	COMM	H0036K147
LBRX	LB PHARMACEUTICALS INC	1,745,015	$38.84M	1.3%	$15.87	+10.1%	COMM	50180M108
XNCR	XENCOR INC	2,452,138	$37.54M	1.2%	$18.82	-20.6%	COMM	98401F105
RVMD	REVOLUTION MEDICINES INC	436,473	$34.77M	1.2%	$39.15	+67.5%	COMM	76155X100
AGIO	AGIOS PHARMACEUTICALS INC	1,181,841	$32.17M	1.1%	$34.05	+3.0%	COMM	00847X104
ARVN	ARVINAS HOLDING CO LLC	2,666,216	$31.62M	1.0%	$8.90	+22.7%	COMM	04335A105
RLAY	RELAY THERAPEUTICS INC	3,220,186	$27.24M	0.9%	$5.27	+35.5%	COMM	75943R102
JANX	JANUX THERAPEUTICS INC	1,789,617	$24.7M	0.8%	$23.52	0.0%	COMM	47103J105
TRDA	ENTRADA THERAPEUTICS INC	2,088,392	$21.47M	0.7%	$12.20	—	COMM	29384C108
MBX	MBX BIOSCIENCES INC	650,000	$20.5M	0.7%	$22.87	+6.1%	COMM	55287L101
UPB	UPSTREAM BIO INC	743,886	$20.2M	0.7%	$22.33	+11.5%	COMM	91678A107
SLN	SILENCE THERAPEUTICS PLC	3,033,560	$18.44M	0.6%	$14.21	—	ADRS	82686Q101
URGN	UROGEN PHARMA LTD	717,347	$16.8M	0.6%	$17.96	+20.8%	COMM	M96088105
ALEC	ALECTOR INC	10,000,000	$15.6M	0.5%	$1.77	0.0%	COMM	014442107
MNPR	MONOPAR THERAPEUTICS INC	141,915	$9.267M	0.3%	$44.70	+82.8%	COMM	61023L207
AVTX	AVALO THERAPEUTICS INC	483,000	$8.771M	0.3%	$10.31	+63.7%	COMM	05338F306
MAZE	MAZE THERAPEUTICS INC	173,816	$7.201M	0.2%	$34.37	0.0%	COMM	578784100
MIRM	MIRUM PHARMACEUTICALS INC	62,049	$4.901M	0.2%	$71.78	0.0%	COMM	604749101
LONA	Athira Pharma, Inc.	464,398	$3.349M	0.1%	$4.58	0.0%	COMM	04746L203
KRRO	KORRO BIO INC	416,301	$3.335M	0.1%	$22.19	+5.3%	COMM	500946108
VTYX	VENTYX BIOSCIENCES INC	316,195	$2.855M	0.1%	$29.94	-75.0%	COMM	92332V107
VTGN	VISTAGEN THERAPEUTICS INC	2,676,580	$1.772M	0.1%	$3.41	+5.9%	COMM	92840H400