Location: Palo Alto, CA
CIK: 0001839948 · Show all filings
Period: Q3 2025 (← Previous) (Next →)
Filing Date: Nov 17, 2025
Total Value: $2.033B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| ABVX | ABIVAX SA AMERICAN DEPOSITARY SHARES | 7,111,596 | $604M | 29.7% | $84.90 | $23.46 | — | ADRS | 00370M103 |
| CGON | CG ONCOLOGY INC | 3,670,206 | $148M | 7.3% | $40.28 * | $40.67 | -28.5% | COMM | 156944100 |
| COGT | COGENT BIOSCIENCES INC | 6,798,162 | $97.62M | 4.8% | $14.36 * | $9.05 | +30.9% | COMM | 19240Q201 |
| AMLX | AMYLYX PHARMACEUTICALS INC | 6,243,812 | $84.85M | 4.2% | $13.59 * | $2.86 | +228.5% | COMM | 03237H101 |
| CNTA | CENTESSA PHARMACEUTICALS PLC | 3,136,480 | $76.06M | 3.7% | $24.25 | $8.56 | — | ADRS | 152309100 |
| TNGX | TANGO THERAPEUTICS INC | 8,536,196 | $71.7M | 3.5% | $8.40 * | $4.64 | +45.8% | COMM | 87583X109 |
| OCUL | OCULAR THERAPEUTIX INC | 6,117,232 | $71.51M | 3.5% | $11.69 * | $7.73 | +54.7% | COMM | 67576A100 |
| DNTH | DIANTHUS THERAPEUTICS INC | 1,676,624 | $65.98M | 3.2% | $39.35 * | $25.70 | -0.5% | COMM | 252828108 |
| — | TOURMALINE BIO INC | 1,311,783 | $62.74M | 3.1% | $47.83 | $25.14 | — | COMM | 89157D105 |
| DYN | DYNE THERAPEUTICS INC | 4,615,144 | $58.38M | 2.9% | $12.65 * | $14.30 | -20.3% | COMM | 26818M108 |
| AGIO | AGIOS PHARMACEUTICALS INC | 1,430,041 | $57.4M | 2.8% | $40.14 * | $34.05 | +10.5% | COMM | 00847X104 |
| EYPT | EYEPOINT PHARMACEUTICALS INC | 3,572,335 | $50.87M | 2.5% | $14.24 * | $10.51 | +9.5% | COMM | 30233G209 |
| FULC | FULCRUM THERAPEUTICS INC | 5,250,000 | $48.3M | 2.4% | $9.20 * | $7.42 | -2.5% | COMM | 359616109 |
| SVRA | SAVARA INC | 12,362,205 | $44.13M | 2.2% | $3.57 * | $3.73 | -20.8% | COMM | 805111101 |
| RAPT | RAPT THERAPEUTICS INC | 1,636,275 | $42.2M | 2.1% | $25.79 * | $7.63 | +71.5% | COMM | 75382E208 |
| TYRA | TYRA BIOSCIENCES INC | 2,898,103 | $40.54M | 2.0% | $13.99 * | $12.78 | -10.8% | COMM | 90240B106 |
| UPB | UPSTREAM BIO INC | 2,117,103 | $39.82M | 2.0% | $18.81 * | $22.33 | -30.4% | COMM | 91678A107 |
| LQDA | LIQUIDIA TECHNOLOGIES INC | 1,710,084 | $38.89M | 1.9% | $22.74 * | $21.69 | 0.0% | COMM | 53635D202 |
| IRON | DISC MEDICINE INC | 465,257 | $30.74M | 1.5% | $66.08 * | $33.98 | +75.1% | COMM | 254604101 |
| GPCR | STRUCTURE THERAPEUTICS INC | 1,063,000 | $29.76M | 1.5% | $28.00 | $43.45 | — | ADRS | 86366E106 |
| XNCR | XENCOR INC | 2,452,138 | $28.76M | 1.4% | $11.73 * | $18.82 | -53.9% | COMM | 98401F105 |
| LBRX | LB PHARMACEUTICALS INC | 1,745,016 | $27.55M | 1.4% | $15.79 | $15.87 | 0.0% | COMM | 50180M108 |
| RVMD | REVOLUTION MEDICINES INC | 436,473 | $20.38M | 1.0% | $46.70 * | $39.15 | 0.0% | COMM | 76155X100 |
| — | ASTRIA THERAPEUTICS INC | 2,761,861 | $20.11M | 1.0% | $7.28 | $14.07 | — | COMM | 04635X102 |
| KRRO | KORRO BIO INC | 416,301 | $19.94M | 1.0% | $47.89 * | $22.19 | 0.0% | COMM | 500946108 |
| KOD | KODIAK SCIENCES INC | 1,145,538 | $18.75M | 0.9% | $16.37 * | $4.16 | +107.0% | COMM | 50015M109 |
| SYRE | SPYRE THERAPEUTICS INC | 1,100,582 | $18.45M | 0.9% | $16.76 * | $16.31 | 0.0% | COMM | 00773J202 |
| SLN | SILENCE THERAPEUTICS PLC | 3,033,560 | $15.74M | 0.8% | $5.19 | $14.21 | — | ADRS | 82686Q101 |
| URGN | UROGEN PHARMA LTD | 717,347 | $14.31M | 0.7% | $19.95 * | $17.96 | 0.0% | COMM | M96088105 |
| ARVN | ARVINAS HOLDING CO LLC | 1,617,365 | $13.78M | 0.7% | $8.52 * | $7.58 | 0.0% | COMM | 04335A105 |
| MNPR | MONOPAR THERAPEUTICS INC | 153,000 | $12.5M | 0.6% | $81.67 * | $44.70 | 0.0% | COMM | 61023L207 |
| MBX | MBX BIOSCIENCES INC | 650,000 | $11.38M | 0.6% | $17.50 * | $22.87 | -41.5% | COMM | 55287L101 |
| VTGN | VISTAGEN THERAPEUTICS INC | 2,676,580 | $9.502M | 0.5% | $3.55 * | $3.41 | -12.4% | COMM | 92840H400 |
| RLAY | RELAY THERAPEUTICS INC | 1,810,351 | $9.45M | 0.5% | $5.22 * | $3.81 | 0.0% | COMM | 75943R102 |
| — | ADVERUM BIOTECHNOLOGIES INC | 1,668,174 | $7.557M | 0.4% | $4.53 | $7.02 | — | COMM | 00773U207 |
| AVTX | AVALO THERAPEUTICS INC | 483,000 | $6.139M | 0.3% | $12.71 * | $10.31 | -16.6% | COMM | 05338F306 |
| ADCT | ADC THERAPEUTICS SA | 1,390,175 | $5.561M | 0.3% | $4.00 * | $3.15 | 0.0% | COMM | H0036K147 |
| PEPG | PEPGEN INC | 1,200,000 | $5.544M | 0.3% | $4.62 * | $1.61 | 0.0% | COMM | 713317105 |
| TRDA | ENTRADA THERAPEUTICS INC | 584,955 | $3.393M | 0.2% | $5.80 | $17.12 | — | COMM | 29384C108 |
| VTYX | VENTYX BIOSCIENCES INC | 316,195 | $983K | 0.0% | $3.11 * | $29.94 | -91.2% | COMM | 92332V107 |