Location: Boston, MA
CIK: 0001583977 · Show all filings
Period: Q4 2020 (← Previous) (Next →)
Filing Date: Feb 16, 2021
Total Value: $4.202B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| — | TURNING POINT THERAPEUTICS I | 2,392,297 | $292M | 6.9% | $40.33 | — | COM | 90041T108 |
| AVIR | ATEA PHARMACEUTICALS INC | 6,411,355 | $260M | 6.2% | $32.23 | 0.0% | COM | 04683R106 |
| QQQ | INVESCO QQQ TR | 750,000 | $235M | 5.6% | — | — | Put | 46090E103 |
| XBI | SPDR SER TR | 1,500,000 | $211M | 5.0% | — | — | Put | 78464A870 |
| SPY | SPDR S&P 500 ETF TR | 500,000 | $187M | 4.4% | — | — | Put | 78462F103 |
| BBIO | BRIDGEBIO PHARMA INC | 2,265,762 | $161M | 3.8% | $27.82 | +73.4% | COM | 10806X102 |
| — | FORMA THERAPEUTICS HLDGS INC | 4,460,000 | $156M | 3.7% | $42.66 | — | SHS | 34633R104 |
| OLMA | OLEMA PHARMACEUTICALS INC | 3,195,544 | $148M | 3.5% | $46.89 | 0.0% | COM | 68062P106 |
| APLS | APELLIS PHARMACEUTICALS INC | 1,866,108 | $107M | 2.5% | $15.50 | +172.8% | COM | 03753U106 |
| RVMD | REVOLUTION MEDICINES INC | 2,495,066 | $98.78M | 2.4% | $27.68 | +42.8% | COM | 76155X100 |
| IWM | ISHARES TR | 500,000 | $98.03M | 2.3% | — | — | Put | 464287655 |
| STOK | STOKE THERAPEUTICS INC | 1,437,807 | $89.04M | 2.1% | $26.85 | +70.7% | COM | 86150R107 |
| — | Y-MABS THERAPEUTICS INC | 1,661,647 | $82.27M | 2.0% | $31.28 | — | COM | 984241109 |
| CCCC | C4 THERAPEUTICS INC | 2,490,065 | $80.02M | 1.9% | $29.00 | 0.0% | COM STK | 12529R107 |
| ALXO | ALX ONCOLOGY HLDGS INC | 881,770 | $76.01M | 1.8% | $39.31 | +53.0% | COM | 00166B105 |
| BEAM | BEAM THERAPEUTICS INC | 924,249 | $75.46M | 1.8% | $25.53 | +92.6% | COM | 07373V105 |
| BCAB | BIOATLA INC | 2,292,060 | $75.42M | 1.8% | $33.43 | 0.0% | COM | 09077B104 |
| RCKT | ROCKET PHARMACEUTICALS INC | 1,368,550 | $75.05M | 1.8% | $16.47 | +121.3% | COM | 77313F106 |
| — | CHEMOCENTRYX INC | 1,200,000 | $74.3M | 1.8% | $23.45 | — | COM | 16383L106 |
| IMVT | IMMUNOVANT INC | 1,562,952 | $72.19M | 1.7% | $30.08 | +53.7% | COM | 45258J102 |
| — | MIRATI THERAPEUTICS INC | 325,000 | $71.38M | 1.7% | $66.72 | — | COM | 60468T105 |
| TARS | TARSUS PHARMACEUTICALS INC | 1,714,269 | $69.97M | 1.7% | $28.48 | 0.0% | COM | 87650L103 |
| RNAM | AVIDITY BIOSCIENCES INC | 2,464,547 | $62.9M | 1.5% | $28.83 | +1.1% | COM | 05370A108 |
| — | REATA PHARMACEUTICALS INC | 500,000 | $61.81M | 1.5% | $66.87 | — | CL A | 75615P103 |
| — | PRAXIS PRECISION MEDICINES I | 1,074,145 | $57.74M | 1.4% | $53.75 | — | COM | 74006W108 |
| OMER | OMEROS CORP | 4,000,000 | $57.14M | 1.4% | $13.60 | -10.2% | COM | 682143102 |
| — | ZYMEWORKS INC | 1,200,000 | $56.71M | 1.3% | $46.09 | — | COM | 98985W102 |
| — | ACCELERON PHARMA INC | 425,000 | $54.37M | 1.3% | $89.87 | — | COM | 00434H108 |
| — | IGM BIOSCIENCES INC | 600,000 | $52.97M | 1.3% | $70.95 | — | COM | 449585108 |
| — | VIELA BIO INC | 1,429,200 | $51.41M | 1.2% | $28.75 | — | COM | 926613100 |
| — | MYOVANT SCIENCES LTD | 1,700,000 | $46.95M | 1.1% | $13.68 | — | COM | G637AM102 |
| — | BIOHAVEN PHARMACTL HLDG CO L | 425,000 | $36.43M | 0.9% | $41.49 | — | COM | G11196105 |
| — | AXONICS MODULATION TECHNOLOG | 693,000 | $34.59M | 0.8% | $15.11 | — | COM | 05465P101 |
| — | ALIGOS THERAPEUTICS INC | 1,267,166 | $34.48M | 0.8% | $27.21 | — | COM | 01626L105 |
| TWST | TWIST BIOSCIENCE CORP | 225,000 | $31.79M | 0.8% | $22.16 | +400.6% | COM | 90184D100 |
| SRNE | SORRENTO THERAPEUTICS INC | 4,500,000 | $30.71M | 0.7% | $2.79 | +187.5% | COM NEW | 83587F202 |
| CRSP | CRISPR THERAPEUTICS AG | 200,000 | $30.62M | 0.7% | $39.27 | +201.0% | NAMEN AKT | H17182108 |
| MASS | 908 DEVICES INC | 545,322 | $29.5M | 0.7% | $58.41 | 0.0% | COM | 65443P102 |
| — | GALECTO INC | 2,150,732 | $26.46M | 0.6% | $12.30 | — | COM | 36322Q107 |
| ZLAB | ZAI LAB LTD | 189,092 | $25.59M | 0.6% | $23.77 | — | ADR | 98887Q104 |
| — | BLUEPRINT MEDICINES CORP | 225,000 | $25.23M | 0.6% | $67.67 | — | COM | 09627Y109 |
| CABA | CABALETTA BIO INC | 1,904,424 | $23.77M | 0.6% | $11.85 | +9.5% | COM | 12674W109 |
| SPRY | SILVERBACK THERAPEUTICS INC | 500,000 | $23.17M | 0.6% | $33.40 | 0.0% | COM | 82835W108 |
| BNTX | BIONTECH SE | 275,000 | $22.42M | 0.5% | $67.76 | — | SPONSORED ADS | 09075V102 |
| — | AGENUS INC | 7,000,000 | $22.26M | 0.5% | $2.45 | — | COM NEW | 00847G705 |
| — | NOVUS THERAPEUTICS INC | 1,415,500 | $21.36M | 0.5% | $15.09 | — | COM | 67011N204 |
| KURA | KURA ONCOLOGY INC | 650,000 | $21.23M | 0.5% | $19.31 | +82.0% | COM | 50127T109 |
| FHTX | FOGHORN THERAPEUTICS INC | 1,000,000 | $20.27M | 0.5% | $19.16 | 0.0% | COM | 344174107 |
| — | AKERO THERAPEUTICS INC | 742,549 | $19.16M | 0.5% | $22.77 | — | COM | 00973Y108 |
| INSP | INSPIRE MED SYS INC | 100,000 | $18.81M | 0.4% | $32.28 | +406.6% | COM | 457730109 |
| — | ALBIREO PHARMA INC | 500,000 | $18.75M | 0.4% | $33.37 | — | COM | 01345P106 |
| — | OTONOMY INC | 2,600,000 | $16.82M | 0.4% | $4.05 | — | COM | 68906L105 |
| ASND | ASCENDIS PHARMA A/S | 100,000 | $16.68M | 0.4% | $79.53 | — | SPONSORED ADR | 04351P101 |
| NTLA | INTELLIA THERAPEUTICS INC | 300,000 | $16.32M | 0.4% | — | — | Put | 45826J105 |
| AXSM | AXSOME THERAPEUTICS INC | 200,000 | $16.29M | 0.4% | $40.39 | +85.1% | COM | 05464T104 |
| — | TCR2 THERAPEUTICS INC | 500,000 | $15.46M | 0.4% | $20.32 | — | COM | 87808K106 |
| OMER | OMEROS CORP | 1,000,000 | $14.29M | 0.3% | $13.60 | -10.2% | Call | 682143102 |
| ANAB | ANAPTYSBIO INC | 650,000 | $13.97M | 0.3% | $23.10 | +5.1% | COM | 032724106 |
| PLRX | PLIANT THERAPEUTICS INC | 611,409 | $13.89M | 0.3% | $26.54 | -5.5% | COM | 729139105 |
| SRPT | SAREPTA THERAPEUTICS INC | 70,000 | $11.93M | 0.3% | $124.50 | +19.0% | COM | 803607100 |
| — | DECIPHERA PHARMACEUTICALS IN | 200,000 | $11.41M | 0.3% | $33.94 | — | COM | 24344T101 |
| — | REPARE THERAPEUTICS INC | 300,000 | $10.29M | 0.2% | $31.02 | — | COM | 760273102 |
| — | HEALTH SCIENCES ACQ CORP 2 | 800,000 | $10.25M | 0.2% | $11.00 | — | ORD SHS | G4411D109 |
| — | ITEOS THERAPEUTICS INC | 300,000 | $10.15M | 0.2% | $24.67 | — | COM | 46565G104 |
| INSM | INSMED INC | 300,000 | $9.987M | 0.2% | $23.70 | +54.1% | COM PAR $.01 | 457669307 |
| — | AKOUOS INC | 499,990 | $9.915M | 0.2% | $21.34 | — | COM | 00973J101 |
| TBPH | THERAVANCE BIOPHARMA INC | 550,000 | $9.773M | 0.2% | $19.27 | -6.8% | COM | G8807B106 |
| — | HARPOON THERAPEUTICS INC | 570,600 | $9.478M | 0.2% | $9.47 | — | COM | 41358P106 |
| — | BCTG ACQUISITION CORP | 800,000 | $9.152M | 0.2% | $10.46 | — | COM | 05492W103 |
| — | SPRINGWORKS THERAPEUTICS INC | 125,000 | $9.065M | 0.2% | $72.52 | — | COM | 85205L107 |
| QURE | UNIQURE NV | 250,000 | $9.032M | 0.2% | $60.55 | -30.3% | SHS | N90064101 |
| ARGX | ARGENX SE | 30,000 | $8.823M | 0.2% | $82.17 | — | SPONSORED ADR | 04016X101 |
| TARA | PROTARA THERAPEUTICS INC | 350,000 | $8.474M | 0.2% | $23.19 | -7.0% | COM STK | 74365U107 |
| FDMT | 4D MOLECULAR THERAPEUTICS IN | 200,000 | $8.29M | 0.2% | $41.28 | 0.0% | COM | 35104E100 |
| GOSS | GOSSAMER BIO INC | 848,382 | $8.204M | 0.2% | $12.02 | -18.1% | COM | 38341P102 |
| — | QUOTIENT LTD | 1,500,000 | $7.815M | 0.2% | $8.95 | — | SHS | G73268107 |
| — | ALLAKOS INC | 50,000 | $7M | 0.2% | $42.85 | — | COM | 01671P100 |
| — | THERAPEUTICS ACQUISITION COR | 500,000 | $6.975M | 0.2% | $14.38 | — | COM CL A | 88339T103 |
| — | MORPHIC HLDG INC | 200,000 | $6.71M | 0.2% | $27.34 | — | COM | 61775R105 |
| — | MERUS N V | 350,000 | $6.136M | 0.1% | $14.08 | — | COM | N5749R100 |
| — | GENETRON HLDGS LTD | 400,000 | $5.6M | 0.1% | $12.07 | — | ADS | 37186H100 |
| — | BCLS ACQUISITION CORP | 500,000 | $5.513M | 0.1% | $11.03 | — | COM CL A | G0904B105 |
| — | FS DEV CORP | 500,000 | $5.5M | 0.1% | $11.20 | — | COM CL A | 303020101 |
| — | 5 01 ACQUISITION CORP | 500,000 | $5.085M | 0.1% | $10.17 | — | COM CL A | 33836P105 |
| — | EIGER BIOPHARMACEUTICALS INC | 400,000 | $4.916M | 0.1% | $10.60 | — | COM | 28249U105 |
| — | VESPER HEALTHCARE ACQSTN COR | 400,000 | $4.848M | 0.1% | $10.26 | — | UNIT 99/99/9999 | 92538T203 |
| REPL | REPLIMUNE GROUP INC | 125,000 | $4.769M | 0.1% | $41.67 | 0.0% | COM | 76029N106 |
| MLTX | HELIX ACQUISITION CORP | 430,000 | $4.742M | 0.1% | $11.03 | — | COM CL A | G4444C102 |
| — | ATRECA INC | 293,500 | $4.74M | 0.1% | $18.84 | — | CL A COM | 04965G109 |
| AUTL | AUTOLUS THERAPEUTICS PLC | 422,167 | $3.774M | 0.1% | $31.47 | — | SPON ADS | 05280R100 |
| — | KADMON HLDGS INC | 850,000 | $3.528M | 0.1% | $5.12 | — | COM | 48283N106 |
| — | AVROBIO INC | 244,032 | $3.402M | 0.1% | $21.11 | — | COM | 05455M100 |
| — | PANACEA ACQUISITION CORP | 250,000 | $3.19M | 0.1% | $12.00 | — | UNIT 99/99/9999 | 698102209 |
| — | TRICIDA INC | 427,975 | $3.017M | 0.1% | $33.32 | — | COM | 89610F101 |
| — | PRECISION BIOSCIENCES INC | 346,524 | $2.89M | 0.1% | $17.95 | — | COM | 74019P108 |
| CRDF | CARDIFF ONCOLOGY INC | 150,000 | $2.699M | 0.1% | $6.60 | +166.2% | COM | 14147L108 |
| — | ARENA PHARMACEUTICALS INC | 20,000 | $1.537M | 0.0% | $42.46 | — | COM NEW | 040047607 |
| — | MIRAGEN THERAPEUTICS INC | 93,126 | $1.532M | 0.0% | $16.45 | — | COM NEW | 60463E202 |
| — | ORCHARD THERAPEUTICS PLC | 256,649 | $1.109M | 0.0% | $16.35 | — | ADS | 68570P101 |
| FATE | FATE THERAPEUTICS INC | 10,000 | $909K | 0.0% | $25.29 | +145.6% | COM | 31189P102 |
| — | CEREVEL THERAPEUTICS HLDNG I | 133,331 | $753K | 0.0% | $5.65 | — | *W EXP 06/09/202 | 15678U102 |
| — | IMV INC | 234,374 | $716K | 0.0% | $3.05 | — | COM | 44974L103 |
| — | NEKTAR THERAPEUTICS | 40,000 | $680K | 0.0% | $44.47 | — | COM | 640268108 |
| — | X4 PHARMACEUTICALS INC | 103,980 | $669K | 0.0% | $6.43 | — | COM | 98420X103 |
| — | MINERVA NEUROSCIENCES INC | 200,000 | $468K | 0.0% | $7.26 | — | COM | 603380106 |