Location: Boston, MA
CIK: 0001583977 · Show all filings
Period: Q1 2021 (← Previous) (Next →)
Filing Date: May 17, 2021
Total Value: $4.489B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| IWM | ISHARES TR | 2,000,000 | $442M | 9.8% | — | — | Put | 464287655 |
| SPY | SPDR S&P 500 ETF TR | 1,000,000 | $396M | 8.8% | — | — | Put | 78462F103 |
| AVIR | ATEA PHARMACEUTICALS INC | 6,411,355 | $396M | 8.8% | $32.23 | +109.6% | COM | 04683R106 |
| — | TURNING POINT THERAPEUTICS I | 2,750,000 | $260M | 5.8% | $47.39 | — | COM | 90041T108 |
| DSGN | DESIGN THERAPEUTICS INC | 5,114,850 | $146M | 3.3% | $31.14 | 0.0% | COM | 25056L103 |
| XBI | SPDR SER TR | 1,000,000 | $136M | 3.0% | — | — | Put | 78464A870 |
| BBIO | BRIDGEBIO PHARMA INC | 2,168,909 | $134M | 3.0% | $27.82 | +135.2% | COM | 10806X102 |
| — | FORMA THERAPEUTICS HLDGS INC | 4,720,000 | $132M | 2.9% | $41.85 | — | SHS | 34633R104 |
| RVMD | REVOLUTION MEDICINES INC | 2,525,000 | $116M | 2.6% | $27.89 | +60.8% | COM | 76155X100 |
| BCAB | BIOATLA INC | 2,192,060 | $110M | 2.4% | $33.43 | +53.3% | COM | 09077B104 |
| OLMA | OLEMA PHARMACEUTICALS INC | 3,195,544 | $105M | 2.3% | $46.89 | -8.6% | COM | 68062P106 |
| CCCC | C4 THERAPEUTICS INC | 2,490,065 | $92.11M | 2.1% | $29.00 | +37.2% | COM STK | 12529R107 |
| APLS | APELLIS PHARMACEUTICALS INC | 1,866,108 | $80.08M | 1.8% | $15.50 | +205.2% | COM | 03753U106 |
| EWTX | EDGEWISE THERAPEUTICS INC | 2,340,914 | $74.31M | 1.7% | $32.43 | 0.0% | COM | 28036F105 |
| ALXO | ALX ONCOLOGY HLDGS INC | 881,770 | $65.02M | 1.4% | $39.31 | +100.2% | COM | 00166B105 |
| — | ZYMEWORKS INC | 2,000,000 | $63.16M | 1.4% | $40.29 | — | COM | 98985W102 |
| RCKT | ROCKET PHARMACEUTICALS INC | 1,368,550 | $60.72M | 1.4% | $16.47 | +233.3% | COM | 77313F106 |
| OMER | OMEROS CORP | 3,300,030 | $58.74M | 1.3% | $13.60 | +43.0% | COM | 682143102 |
| STOK | STOKE THERAPEUTICS INC | 1,437,807 | $55.84M | 1.2% | $26.85 | +112.0% | COM | 86150R107 |
| TARS | TARSUS PHARMACEUTICALS INC | 1,714,269 | $55.25M | 1.2% | $28.48 | +29.8% | COM | 87650L103 |
| RNAM | AVIDITY BIOSCIENCES INC | 2,464,545 | $53.75M | 1.2% | $28.83 | -15.1% | COM | 05370A108 |
| ACRS | ACLARIS THERAPEUTICS INC | 2,000,000 | $50.4M | 1.1% | $19.56 | 0.0% | COM | 00461U105 |
| — | MIRATI THERAPEUTICS INC | 275,000 | $47.11M | 1.0% | $66.72 | — | COM | 60468T105 |
| NVAX | NOVAVAX INC | 250,000 | $45.33M | 1.0% | $199.27 | 0.0% | COM NEW | 670002401 |
| — | CHEMOCENTRYX INC | 850,000 | $43.55M | 1.0% | $23.45 | — | COM | 16383L106 |
| — | AXONICS MODULATION TECHNOLOG | 693,000 | $41.5M | 0.9% | $15.11 | — | COM | 05465P101 |
| DMTKQ | DERMTECH INC | 800,000 | $40.63M | 0.9% | $50.79 | — | COM | 24984K105 |
| — | REATA PHARMACEUTICALS INC | 400,000 | $39.88M | 0.9% | $66.87 | — | CL A | 75615P103 |
| — | IGM BIOSCIENCES INC | 495,769 | $38.02M | 0.8% | $70.95 | — | COM | 449585108 |
| — | ACCELERON PHARMA INC | 275,000 | $37.29M | 0.8% | $89.87 | — | COM | 00434H108 |
| — | Y-MABS THERAPEUTICS INC | 1,230,000 | $37.2M | 0.8% | $31.28 | — | COM | 984241109 |
| — | LONGBOARD PHARMACEUTICALS IN | 2,356,000 | $37.19M | 0.8% | $15.79 | — | COM | 54300N103 |
| — | PROMETHEUS BIOSCIENCES INC | 2,098,024 | $36.62M | 0.8% | $17.46 | — | COM | 74349U108 |
| — | PRAXIS PRECISION MEDICINES I | 1,074,145 | $35.19M | 0.8% | $53.75 | — | COM | 74006W108 |
| — | VERU INC | 3,000,000 | $32.33M | 0.7% | $10.78 | — | COM | 92536C103 |
| — | ALIGOS THERAPEUTICS INC | 1,267,167 | $28.82M | 0.6% | $27.21 | — | COM | 01626L105 |
| MASS | 908 DEVICES INC | 545,322 | $25.92M | 0.6% | $58.41 | -2.2% | COM | 65443P102 |
| NTLA | INTELLIA THERAPEUTICS INC | 300,000 | $24.07M | 0.5% | — | — | Put | 45826J105 |
| PLRX | PLIANT THERAPEUTICS INC | 611,409 | $24.05M | 0.5% | $26.54 | +22.4% | COM | 729139105 |
| — | BLUEPRINT MEDICINES CORP | 247,200 | $24.04M | 0.5% | $70.32 | — | COM | 09627Y109 |
| — | APTOSE BIOSCIENCES INC | 4,000,000 | $23.9M | 0.5% | $5.97 | — | COM NEW | 03835T200 |
| PHVS | PHARVARIS N V | 864,143 | $23.81M | 0.5% | $31.46 | 0.0% | COM | N69605108 |
| TWST | TWIST BIOSCIENCE CORP | 185,000 | $22.91M | 0.5% | $22.16 | +585.2% | COM | 90184D100 |
| SRNE | SORRENTO THERAPEUTICS INC | 2,750,000 | $22.74M | 0.5% | $2.79 | +278.0% | COM NEW | 83587F202 |
| — | MORPHIC HLDG INC | 350,000 | $22.15M | 0.5% | $42.74 | — | COM | 61775R105 |
| SPRY | SILVERBACK THERAPEUTICS INC | 500,000 | $21.82M | 0.5% | $33.40 | +41.7% | COM | 82835W108 |
| — | AKERO THERAPEUTICS INC | 742,549 | $21.54M | 0.5% | $22.77 | — | COM | 00973Y108 |
| CABA | CABALETTA BIO INC | 1,904,424 | $21.14M | 0.5% | $11.85 | +3.1% | COM | 12674W109 |
| — | AGENUS INC | 7,750,000 | $21.08M | 0.5% | $2.48 | — | COM NEW | 00847G705 |
| — | MYOVANT SCIENCES LTD | 1,000,000 | $20.58M | 0.5% | $13.68 | — | COM | G637AM102 |
| ZLAB | ZAI LAB LTD | 150,000 | $20.01M | 0.4% | $23.77 | — | ADR | 98887Q104 |
| — | TCR2 THERAPEUTICS INC | 900,000 | $19.87M | 0.4% | $21.10 | — | COM | 87808K106 |
| KALV | KALVISTA PHARMACEUTICALS INC | 750,000 | $19.27M | 0.4% | $26.28 | 0.0% | COM | 483497103 |
| — | HUMANIGEN INC | 1,000,000 | $19.1M | 0.4% | $19.10 | — | COM NEW | 444863203 |
| — | CONNECT BIOPHARMA HLDGS LTD | 1,000,000 | $18.5M | 0.4% | $18.50 | — | ADS | 207523101 |
| OMER | OMEROS CORP | 1,000,000 | $17.8M | 0.4% | $13.60 | +43.0% | Call | 682143102 |
| — | ALBIREO PHARMA INC | 500,000 | $17.63M | 0.4% | $33.37 | — | COM | 01345P106 |
| INSP | INSPIRE MED SYS INC | 85,000 | $17.59M | 0.4% | $32.28 | +558.4% | COM | 457730109 |
| ELDN | ELEDON PHARMACEUTICALS INC | 1,415,500 | $15.15M | 0.3% | $15.09 | 0.0% | COM | 28617K101 |
| — | REPARE THERAPEUTICS INC | 462,205 | $14.19M | 0.3% | $30.90 | — | COM | 760273102 |
| ANAB | ANAPTYSBIO INC | 650,000 | $14.01M | 0.3% | $23.10 | +9.3% | COM | 032724106 |
| BEAM | BEAM THERAPEUTICS INC | 171,775 | $13.75M | 0.3% | $25.53 | +272.6% | COM | 07373V105 |
| — | BIOHAVEN PHARMACTL HLDG CO L | 200,000 | $13.67M | 0.3% | $41.49 | — | COM | G11196105 |
| FHTX | FOGHORN THERAPEUTICS INC | 1,000,000 | $13.18M | 0.3% | $19.16 | -14.5% | COM | 344174107 |
| — | GALECTO INC | 2,150,732 | $13.07M | 0.3% | $12.30 | — | COM | 36322Q107 |
| ASND | ASCENDIS PHARMA A/S | 100,000 | $12.89M | 0.3% | $79.53 | — | SPONSORED ADR | 04351P101 |
| — | HARPOON THERAPEUTICS INC | 570,600 | $11.94M | 0.3% | $9.47 | — | COM | 41358P106 |
| AXSM | AXSOME THERAPEUTICS INC | 200,000 | $11.32M | 0.3% | $40.39 | +74.2% | COM | 05464T104 |
| TBPH | THERAVANCE BIOPHARMA INC | 550,000 | $11.23M | 0.3% | $19.27 | -1.4% | COM | G8807B106 |
| — | AVEO PHARMACEUTICALS INC | 1,500,000 | $10.98M | 0.2% | $7.32 | — | COM NEW | 053588307 |
| BNTX | BIONTECH SE | 100,000 | $10.92M | 0.2% | $67.76 | — | SPONSORED ADS | 09075V102 |
| — | ITEOS THERAPEUTICS INC | 300,000 | $10.25M | 0.2% | $24.67 | — | COM | 46565G104 |
| INSM | INSMED INC | 300,000 | $10.22M | 0.2% | $23.70 | +61.2% | COM PAR $.01 | 457669307 |
| — | SPRINGWORKS THERAPEUTICS INC | 125,000 | $9.196M | 0.2% | $72.52 | — | COM | 85205L107 |
| — | HEALTH SCIENCES ACQ CORP 2 | 800,000 | $8.984M | 0.2% | $11.00 | — | ORD SHS | G4411D109 |
| — | DECIPHERA PHARMACEUTICALS IN | 200,000 | $8.968M | 0.2% | $33.94 | — | COM | 24344T101 |
| — | BCTG ACQUISITION CORP | 800,000 | $8.896M | 0.2% | $10.46 | — | COM | 05492W103 |
| FDMT | 4D MOLECULAR THERAPEUTICS IN | 200,000 | $8.676M | 0.2% | $41.28 | +7.3% | COM | 35104E100 |
| QURE | UNIQURE NV | 250,000 | $8.422M | 0.2% | $60.55 | -40.8% | SHS | N90064101 |
| ARGX | ARGENX SE | 30,000 | $8.262M | 0.2% | $82.17 | — | SPONSORED ADR | 04016X101 |
| GOSS | GOSSAMER BIO INC | 848,382 | $7.848M | 0.2% | $12.02 | -16.2% | COM | 38341P102 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 459,144 | $7.672M | 0.2% | $18.72 | 0.0% | COM | 92790C104 |
| — | MERUS N V | 350,000 | $7.311M | 0.2% | $14.08 | — | COM | N5749R100 |
| — | MAGENTA THERAPEUTICS INC | 600,000 | $7.104M | 0.2% | $11.84 | — | COM | 55910K108 |
| — | AKOUOS INC | 499,989 | $6.935M | 0.2% | $21.34 | — | COM | 00973J101 |
| — | GENETRON HLDGS LTD | 300,000 | $6.438M | 0.1% | $12.07 | — | ADS | 37186H100 |
| — | GEMINI THERAPEUTICS INC | 475,000 | $6.436M | 0.1% | $13.55 | — | COM | 36870G105 |
| CGEM | CULLINAN ONCOLOGY INC | 150,000 | $6.25M | 0.1% | $40.60 | 0.0% | COM | 230031106 |
| — | QUOTIENT LTD | 1,500,000 | $5.52M | 0.1% | $8.95 | — | SHS | G73268107 |
| TARA | PROTARA THERAPEUTICS INC | 350,000 | $5.509M | 0.1% | $23.19 | -20.0% | COM STK | 74365U107 |
| IMVT | IMMUNOVANT INC | 337,048 | $5.406M | 0.1% | $30.08 | -12.3% | COM | 45258J102 |
| — | BCLS ACQUISITION CORP | 500,000 | $5.285M | 0.1% | $11.03 | — | COM CL A | G0904B105 |
| — | THERAPEUTICS ACQUISITION COR | 500,000 | $5.255M | 0.1% | $14.38 | — | COM CL A | 88339T103 |
| SRPT | SAREPTA THERAPEUTICS INC | 70,000 | $5.217M | 0.1% | $124.50 | -25.9% | COM | 803607100 |
| — | 5 01 ACQUISITION CORP | 500,000 | $4.988M | 0.1% | $10.17 | — | COM CL A | 33836P105 |
| — | VESPER HEALTHCARE ACQSTN COR | 400,000 | $4.62M | 0.1% | $10.26 | — | UNIT 99/99/9999 | 92538T203 |
| — | ATRECA INC | 293,500 | $4.499M | 0.1% | $18.84 | — | CL A COM | 04965G109 |
| MLTX | HELIX ACQUISITION CORP | 430,000 | $4.386M | 0.1% | $11.03 | — | COM CL A | G4444C102 |
| REPL | REPLIMUNE GROUP INC | 125,000 | $3.814M | 0.1% | $41.67 | -10.1% | COM | 76029N106 |
| — | INSTIL BIO INC | 150,000 | $3.762M | 0.1% | $25.08 | — | COM | 45783C101 |
| — | PRECISION BIOSCIENCES INC | 346,524 | $3.587M | 0.1% | $17.95 | — | COM | 74019P108 |
| — | EIGER BIOPHARMACEUTICALS INC | 400,000 | $3.54M | 0.1% | $10.60 | — | COM | 28249U105 |
| — | KADMON HLDGS INC | 750,000 | $2.918M | 0.1% | $5.12 | — | COM | 48283N106 |
| — | ALLAKOS INC | 25,000 | $2.87M | 0.1% | $42.85 | — | COM | 01671P100 |
| NUVB | NUVATION BIO INC | 234,445 | $2.45M | 0.1% | $11.18 | 0.0% | COM CL A | 67080N101 |
| AUTL | AUTOLUS THERAPEUTICS PLC | 422,167 | $2.419M | 0.1% | $31.47 | — | SPON ADS | 05280R100 |
| — | KINIKSA PHARMACEUTICALS LTD | 130,000 | $2.406M | 0.1% | $18.51 | — | COM CL A | G5269C101 |
| — | TRICIDA INC | 427,975 | $2.264M | 0.1% | $33.32 | — | COM | 89610F101 |
| — | GRACELL BIOTECHNOLOGIES INC | 125,000 | $1.925M | 0.0% | $15.40 | — | SPONSORED ADS | 38406L103 |
| — | ORCHARD THERAPEUTICS PLC | 256,649 | $1.863M | 0.0% | $16.35 | — | ADS | 68570P101 |
| CRDF | CARDIFF ONCOLOGY INC | 150,000 | $1.389M | 0.0% | $6.60 | +84.0% | COM | 14147L108 |
| — | ARENA PHARMACEUTICALS INC | 20,000 | $1.388M | 0.0% | $42.46 | — | COM NEW | 040047607 |
| — | X4 PHARMACEUTICALS INC | 103,980 | $895K | 0.0% | $6.43 | — | COM | 98420X103 |
| FATE | FATE THERAPEUTICS INC | 10,000 | $824K | 0.0% | $25.29 | +278.9% | COM | 31189P102 |
| — | IMV INC | 234,374 | $772K | 0.0% | $3.05 | — | COM | 44974L103 |
| — | MINERVA NEUROSCIENCES INC | 200,000 | $584K | 0.0% | $7.26 | — | COM | 603380106 |
| — | CEREVEL THERAPEUTICS HLDNG I | 133,331 | $563K | 0.0% | $5.65 | — | *W EXP 06/09/202 | 15678U102 |
| — | OUTLOOK THERAPEUTICS INC | 416,666 | $421K | 0.0% | $1.01 | — | *W EXP 02/18/202 | 69012T115 |
| — | NEKTAR THERAPEUTICS | 20,000 | $400K | 0.0% | $44.47 | — | COM | 640268108 |
| — | NUVATION BIO INC | 83,332 | $222K | 0.0% | $2.66 | — | *W EXP 07/07/202 | 67080N119 |