Location: Boston, MA
CIK: 0001583977 · Show all filings
Period: Q2 2021 (← Previous) (Next →)
Filing Date: Aug 16, 2021
Total Value: $2.944B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| — | TURNING POINT THERAPEUTICS I | 3,037,042 | $237M | 8.0% | $50.29 | — | COM | 90041T108 |
| IWM | ISHARES TR | 1,000,000 | $229M | 7.8% | — | — | Put | 464287655 |
| AVIR | ATEA PHARMACEUTICALS INC | 6,411,355 | $138M | 4.7% | $32.23 | -6.8% | COM | 04683R106 |
| — | FORMA THERAPEUTICS HLDGS INC | 4,721,589 | $118M | 4.0% | $41.85 | — | SHS | 34633R104 |
| BBIO | BRIDGEBIO PHARMA INC | 1,880,980 | $115M | 3.9% | $27.82 | +105.3% | COM | 10806X102 |
| DSGN | DESIGN THERAPEUTICS INC | 5,414,850 | $106M | 3.6% | $30.82 | -18.1% | COM | 25056L103 |
| RVMD | REVOLUTION MEDICINES INC | 3,338,166 | $106M | 3.6% | $29.60 | +17.9% | COM | 76155X100 |
| OLMA | OLEMA PHARMACEUTICALS INC | 3,073,485 | $86M | 2.9% | $46.89 | -39.3% | COM | 68062P106 |
| BCAB | BIOATLA INC | 1,951,718 | $82.71M | 2.8% | $33.43 | +35.2% | COM | 09077B104 |
| GLUE | MONTE ROSA THERAPEUTICS INC | 3,193,973 | $69.55M | 2.4% | $20.37 | 0.0% | COM | 61225M102 |
| ARKG | ARK ETF TR | 750,000 | $69.38M | 2.4% | — | — | Put | 00214Q302 |
| EWTX | EDGEWISE THERAPEUTICS INC | 3,140,914 | $66.53M | 2.3% | $31.13 | -12.2% | COM | 28036F105 |
| ARKK | ARK ETF TR | 500,000 | $65.39M | 2.2% | — | — | Put | 00214Q104 |
| RNAM | AVIDITY BIOSCIENCES INC | 2,228,667 | $55.07M | 1.9% | $28.83 | -19.3% | COM | 05370A108 |
| APLS | APELLIS PHARMACEUTICALS INC | 850,000 | $53.72M | 1.8% | $15.50 | +232.8% | COM | 03753U106 |
| ALXO | ALX ONCOLOGY HLDGS INC | 889,454 | $48.63M | 1.7% | $39.31 | +52.2% | COM | 00166B105 |
| BMEA | BIOMEA FUSION INC | 3,170,872 | $48.43M | 1.6% | $17.65 | 0.0% | COM | 09077A106 |
| — | AMBRX BIOPHARMA INC | 2,486,386 | $47.03M | 1.6% | $18.92 | — | SPONSORED ADS | 02290A102 |
| — | ZYMEWORKS INC | 1,321,936 | $45.86M | 1.6% | $40.29 | — | COM | 98985W102 |
| — | AEROVATE THERAPEUTICS INC | 2,030,691 | $44.61M | 1.5% | $21.97 | — | COM | 008064107 |
| — | PROMETHEUS BIOSCIENCES INC | 1,848,024 | $44.48M | 1.5% | $17.46 | — | COM | 74349U108 |
| TARS | TARSUS PHARMACEUTICALS INC | 1,514,269 | $43.88M | 1.5% | $28.48 | +9.6% | COM | 87650L103 |
| STOK | STOKE THERAPEUTICS INC | 1,278,276 | $43.03M | 1.5% | $26.85 | +31.6% | COM | 86150R107 |
| RCKT | ROCKET PHARMACEUTICALS INC | 968,550 | $42.9M | 1.5% | $16.47 | +163.6% | COM | 77313F106 |
| — | VERVE THERAPEUTICS INC | 709,224 | $40.59M | 1.4% | $57.24 | — | COM | 92539P101 |
| — | RAIN THERAPEUTICS INC | 2,626,660 | $39.73M | 1.3% | $15.13 | — | COM | 75082Q105 |
| ACRS | ACLARIS THERAPEUTICS INC | 2,000,000 | $35.12M | 1.2% | $19.56 | +16.2% | COM | 00461U105 |
| CNTA | CENTESSA PHARMACEUTICALS PLC | 1,427,273 | $31.05M | 1.1% | $21.76 | — | SPONSORED ADS | 152309100 |
| — | MIRATI THERAPEUTICS INC | 175,000 | $28.27M | 1.0% | $66.72 | — | COM | 60468T105 |
| — | Y-MABS THERAPEUTICS INC | 800,000 | $27.04M | 0.9% | $31.28 | — | COM | 984241109 |
| — | AGENUS INC | 4,807,557 | $26.39M | 0.9% | $2.48 | — | COM NEW | 00847G705 |
| — | ELEVATION ONCOLOGY INC | 1,983,165 | $25.57M | 0.9% | $12.89 | — | COM | 28623U101 |
| — | VECTIVBIO HLDG AG | 2,226,128 | $25.53M | 0.9% | $11.47 | — | ORD SHS | H9060V101 |
| TWST | TWIST BIOSCIENCE CORP | 185,000 | $24.65M | 0.8% | $22.16 | +424.6% | COM | 90184D100 |
| — | REATA PHARMACEUTICALS INC | 168,150 | $23.8M | 0.8% | $66.87 | — | CL A | 75615P103 |
| — | ACCELERON PHARMA INC | 175,000 | $21.96M | 0.7% | $89.87 | — | COM | 00434H108 |
| MASS | 908 DEVICES INC | 545,320 | $21.13M | 0.7% | $58.41 | -22.5% | COM | 65443P102 |
| — | BLUEPRINT MEDICINES CORP | 237,546 | $20.89M | 0.7% | $70.32 | — | COM | 09627Y109 |
| — | LONGBOARD PHARMACEUTICALS IN | 2,321,403 | $20.87M | 0.7% | $15.79 | — | COM | 54300N103 |
| — | IGM BIOSCIENCES INC | 250,000 | $20.8M | 0.7% | $70.95 | — | COM | 449585108 |
| — | AXONICS INC | 322,240 | $20.43M | 0.7% | $15.11 | — | COM | 05465P101 |
| — | PRAXIS PRECISION MEDICINES I | 1,024,145 | $18.72M | 0.6% | $53.75 | — | COM | 74006W108 |
| DMTKQ | DERMTECH INC | 450,000 | $18.71M | 0.6% | $50.79 | — | COM | 24984K105 |
| — | ALIGOS THERAPEUTICS INC | 905,467 | $18.46M | 0.6% | $27.21 | — | COM | 01626L105 |
| OMER | OMEROS CORP | 1,200,000 | $17.81M | 0.6% | $13.60 | +23.4% | COM | 682143102 |
| — | TALARIS THERAPEUTICS INC | 1,215,847 | $17.26M | 0.6% | $14.20 | — | COM | 87410C104 |
| — | AKERO THERAPEUTICS INC | 600,000 | $14.89M | 0.5% | $22.77 | — | COM | 00973Y108 |
| OMER | OMEROS CORP | 1,000,000 | $14.84M | 0.5% | $13.60 | +23.4% | Call | 682143102 |
| PLRX | PLIANT THERAPEUTICS INC | 482,413 | $14.05M | 0.5% | $26.54 | +17.3% | COM | 729139105 |
| CABA | CABALETTA BIO INC | 1,611,623 | $13.86M | 0.5% | $11.85 | -17.1% | COM | 12674W109 |
| PHVS | PHARVARIS N V | 744,863 | $13.63M | 0.5% | $31.46 | -27.9% | COM | N69605108 |
| CCCC | C4 THERAPEUTICS INC | 354,495 | $13.41M | 0.5% | $29.00 | +23.5% | COM STK | 12529R107 |
| BEAM | BEAM THERAPEUTICS INC | 100,000 | $12.87M | 0.4% | $25.53 | +212.1% | COM | 07373V105 |
| — | CONNECT BIOPHARMA HLDGS LTD | 650,000 | $12.69M | 0.4% | $18.50 | — | ADS | 207523101 |
| — | APTOSE BIOSCIENCES INC | 3,807,200 | $12.64M | 0.4% | $5.97 | — | COM NEW | 03835T200 |
| GHRS | GH RESEARCH PLC | 608,123 | $12.55M | 0.4% | $20.43 | 0.0% | ORDINARY SHARES | G3855L106 |
| — | MYOVANT SCIENCES LTD | 542,499 | $12.35M | 0.4% | $13.68 | — | COM | G637AM102 |
| — | REPARE THERAPEUTICS INC | 363,766 | $11.34M | 0.4% | $30.90 | — | COM | 760273102 |
| ELDN | ELEDON PHARMACEUTICALS INC | 1,415,500 | $11.2M | 0.4% | $15.09 | -37.5% | COM | 28617K101 |
| — | MORPHIC HLDG INC | 189,774 | $10.89M | 0.4% | $42.74 | — | COM | 61775R105 |
| — | HUMANIGEN INC | 600,000 | $10.43M | 0.4% | $19.10 | — | COM NEW | 444863203 |
| ANAB | ANAPTYSBIO INC | 385,081 | $9.985M | 0.3% | $23.10 | +3.8% | COM | 032724106 |
| ASND | ASCENDIS PHARMA A/S | 75,000 | $9.866M | 0.3% | $79.53 | — | SPONSORED ADR | 04351P101 |
| ZLAB | ZAI LAB LTD | 53,455 | $9.461M | 0.3% | $23.77 | — | ADR | 98887Q104 |
| INSP | INSPIRE MED SYS INC | 48,132 | $9.302M | 0.3% | $32.28 | +514.5% | COM | 457730109 |
| — | BCTG ACQUISITION CORP | 800,000 | $9.096M | 0.3% | $10.46 | — | COM | 05492W103 |
| — | GALECTO INC | 1,753,839 | $8.874M | 0.3% | $12.30 | — | COM | 36322Q107 |
| — | TCR2 THERAPEUTICS INC | 479,506 | $7.869M | 0.3% | $21.10 | — | COM | 87808K106 |
| — | HARPOON THERAPEUTICS INC | 540,600 | $7.498M | 0.3% | $9.47 | — | COM | 41358P106 |
| — | CATABASIS PHARMACEUTICALS IN | 3,550,000 | $7.49M | 0.3% | $2.11 | — | COM NEW | 14875P206 |
| — | ITEOS THERAPEUTICS INC | 288,330 | $7.396M | 0.3% | $24.67 | — | COM | 46565G104 |
| SPRY | SILVERBACK THERAPEUTICS INC | 239,099 | $7.386M | 0.3% | $33.40 | -4.0% | COM | 82835W108 |
| QURE | UNIQURE NV | 239,548 | $7.378M | 0.3% | $60.55 | -44.7% | SHS | N90064101 |
| INSM | INSMED INC | 250,000 | $7.115M | 0.2% | $23.70 | +25.2% | COM PAR $.01 | 457669307 |
| — | VERU INC | 800,000 | $6.456M | 0.2% | $10.78 | — | COM | 92536C103 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 342,962 | $6.273M | 0.2% | $18.72 | -8.6% | COM | 92790C104 |
| — | MERUS N V | 285,096 | $6.007M | 0.2% | $14.08 | — | COM | N5749R100 |
| — | GRAPHITE BIO INC | 203,153 | $5.931M | 0.2% | $29.19 | — | COM | 38870X104 |
| — | AVEO PHARMACEUTICALS INC | 893,500 | $5.888M | 0.2% | $7.32 | — | COM NEW | 053588307 |
| — | DECIPHERA PHARMACEUTICALS IN | 144,439 | $5.288M | 0.2% | $33.94 | — | COM | 24344T101 |
| — | AKOUOS INC | 394,500 | $4.951M | 0.2% | $21.34 | — | COM | 00973J101 |
| SRNE | SORRENTO THERAPEUTICS INC | 500,000 | $4.845M | 0.2% | $2.79 | +185.1% | COM NEW | 83587F202 |
| — | MAGENTA THERAPEUTICS INC | 478,200 | $4.677M | 0.2% | $11.84 | — | COM | 55910K108 |
| MLTX | HELIX ACQUISITION CORP | 430,000 | $4.45M | 0.2% | $11.03 | — | COM CL A | G4444C102 |
| — | QUOTIENT LTD | 1,203,328 | $4.38M | 0.1% | $8.95 | — | SHS | G73268107 |
| TBPH | THERAVANCE BIOPHARMA INC | 300,000 | $4.356M | 0.1% | $19.27 | -2.6% | COM | G8807B106 |
| — | PRECISION BIOSCIENCES INC | 346,524 | $4.338M | 0.1% | $17.95 | — | COM | 74019P108 |
| — | 5 01 ACQUISITION CORP | 400,000 | $3.988M | 0.1% | $10.17 | — | COM CL A | 33836P105 |
| — | GENETRON HLDGS LTD | 132,867 | $2.676M | 0.1% | $12.07 | — | ADS | 37186H100 |
| AUTL | AUTOLUS THERAPEUTICS PLC | 392,167 | $2.604M | 0.1% | $31.47 | — | SPON ADS | 05280R100 |
| — | HEALTH SCIENCES ACQ CORP 2 | 240,000 | $2.448M | 0.1% | $11.00 | — | ORD SHS | G4411D109 |
| — | EIGER BIOPHARMACEUTICALS INC | 284,988 | $2.428M | 0.1% | $10.60 | — | COM | 28249U105 |
| — | ATRECA INC | 273,500 | $2.33M | 0.1% | $18.84 | — | CL A COM | 04965G109 |
| — | TRICIDA INC | 427,975 | $1.849M | 0.1% | $33.32 | — | COM | 89610F101 |
| GOSS | GOSSAMER BIO INC | 198,382 | $1.611M | 0.1% | $12.02 | -27.9% | COM | 38341P102 |
| — | SPRINGWORKS THERAPEUTICS INC | 15,000 | $1.236M | 0.0% | $72.52 | — | COM | 85205L107 |
| — | ORCHARD THERAPEUTICS PLC | 256,649 | $1.127M | 0.0% | $16.35 | — | ADS | 68570P101 |
| — | X4 PHARMACEUTICALS INC | 103,980 | $676K | 0.0% | $6.43 | — | COM | 98420X103 |
| CRDF | CARDIFF ONCOLOGY INC | 95,720 | $637K | 0.0% | $6.60 | +28.4% | COM | 14147L108 |
| — | MINERVA NEUROSCIENCES INC | 245,744 | $570K | 0.0% | $6.34 | — | COM | 603380106 |
| — | IMV INC | 234,374 | $507K | 0.0% | $3.05 | — | COM | 44974L103 |
| — | CEREVEL THERAPEUTICS HLDNG I | 19,316 | $278K | 0.0% | $5.65 | — | *W EXP 06/09/202 | 15678U102 |
| — | NUVATION BIO INC | 83,332 | $217K | 0.0% | $2.66 | — | *W EXP 07/07/202 | 67080N119 |
| — | OUTLOOK THERAPEUTICS INC | 416,666 | $130K | 0.0% | $1.01 | — | *W EXP 02/18/202 | 69012T115 |