Octagon Capital Advisors LP Quant / Systematic

CIK: 0001839435 · Show all filings

Period: Q1 2025 (← Previous) (Next →)

Filing Date: May 16, 2025

Total Value ($000): $516,795 (100.0% shares, 0.0% debt)

Holdings (35)

— NUVATION BIO INC 9.3%

Value ($000) $48,102 Shares 27,330,800 Est. Cost $1.77 Unrealized —

APLS APELLIS PHARMACEUTICALS INC 8.9%

Value ($000) $45,796 Shares 2,094,000 Est. Cost $47.09 Unrealized -41.3%

DNTH DIANTHUS THERAPEUTICS INC 8.2%

Value ($000) $42,478 Shares 2,341,667 Est. Cost $20.54 Unrealized +7.3%

AVBP ARRIVENT BIOPHARMA INC 7.4%

Value ($000) $38,078 Shares 2,059,387 Est. Cost $20.73 Unrealized +18.1%

TRVI TREVI THERAPEUTICS INC 4.0%

Value ($000) $20,895 Shares 3,322,000 Est. Cost $4.77 Unrealized 0.0%

CNTA CENTESSA PHARMACEUTICALS PLC 4.0%

Value ($000) $20,492 Shares 1,425,000 Est. Cost $7.34 Unrealized —

GOSS GOSSAMER BIO INC 3.9%

Value ($000) $20,185 Shares 18,350,000 Est. Cost $1.89 Unrealized -39.0%

OCUL OCULAR THERAPEUTIX INC 3.4%

Value ($000) $17,775 Shares 2,425,000 Est. Cost $7.10 Unrealized +8.3%

— MIND MEDICINE MINDMED INC 3.4%

Value ($000) $17,655 Shares 3,018,000 Est. Cost $8.34 Unrealized —

COGT COGENT BIOSCIENCES INC 3.2%

Value ($000) $16,550 Shares 2,763,000 Est. Cost $9.86 Unrealized -20.5%

KALV KALVISTA PHARMACEUTICALS INC 3.1%

Value ($000) $15,810 Shares 1,370,000 Est. Cost $10.36 Unrealized -1.5%

TSHA TAYSHA GENE THERAPIES INC 2.9%

Value ($000) $14,873 Shares 10,700,000 Est. Cost $2.19 Unrealized -23.6%

NUVB NUVATION BIO INC 2.7%

Value ($000) $13,904 Shares 7,900,000 Est. Cost $2.99 Unrealized -24.0%

— VERONA PHARMA PLC 2.7%

Value ($000) $13,794 Shares 217,264 Est. Cost $17.59 Unrealized —

— TOURMALINE BIO INC 2.7%

Value ($000) $13,765 Shares 905,000 Est. Cost $15.21 Unrealized —

— MERUS N V 2.5%

Value ($000) $12,964 Shares 308,000 Est. Cost $42.05 Unrealized —

PHVS PHARVARIS N V 2.3%

Value ($000) $12,086 Shares 769,815 Est. Cost $18.74 Unrealized -10.0%

MLTX MOONLAKE IMMUNOTHERAPEUTICS 2.2%

Value ($000) $11,565 Shares 296,000 Est. Cost $43.09 Unrealized 0.0%

SNDX SYNDAX PHARMACEUTICALS INC 2.1%

Value ($000) $11,106 Shares 904,000 Est. Cost $17.11 Unrealized -17.6%

ATYR ATYR PHARMA INC 2.1%

Value ($000) $10,727 Shares 3,552,000 Est. Cost $3.49 Unrealized +4.5%

SRRK SCHOLAR ROCK HLDG CORP 2.0%

Value ($000) $10,577 Shares 329,000 Est. Cost $32.56 Unrealized +18.1%

VSTM VERASTEM INC 2.0%

Value ($000) $10,372 Shares 1,720,000 Est. Cost $6.11 Unrealized 0.0%

CNTA CENTESSA PHARMACEUTICALS PLC 1.7%

Value ($000) $8,628 Shares 600,000 Est. Cost $7.34 Unrealized —

— REGULUS THERAPEUTICS INC 1.6%

Value ($000) $8,115 Shares 4,637,076 Est. Cost $1.76 Unrealized —

SPRY ARS PHARMACEUTICALS INC 1.5%

Value ($000) $7,863 Shares 625,000 Est. Cost $12.03 Unrealized 0.0%

ABVX ABIVAX SA 1.5%

Value ($000) $7,688 Shares 1,230,000 Est. Cost $6.25 Unrealized —

ERAS ERASCA INC 1.4%

Value ($000) $7,037 Shares 5,136,795 Est. Cost $2.74 Unrealized -37.4%

VRDN VIRIDIAN THERAPEUTICS INC 1.2%

Value ($000) $6,066 Shares 450,000 Est. Cost $22.43 Unrealized -24.1%

CRBP CORBUS PHARMACEUTICALS HLDGS 1.1%

Value ($000) $5,921 Shares 1,115,000 Est. Cost $40.87 Unrealized -78.4%

— UNICYCIVE THERAPEUTICS INC 1.1%

Value ($000) $5,749 Shares 10,000,000 Est. Cost $0.46 Unrealized —

MAZE MAZE THERAPEUTICS INC 1.0%

Value ($000) $5,153 Shares 468,000 Est. Cost $12.04 Unrealized 0.0%

CATX PERSPECTIVE THERAPEUTICS INC 0.9%

Value ($000) $4,793 Shares 2,250,000 Est. Cost $12.05 Unrealized -75.1%

KLRS KALARIS THERAPEUTICS INC 0.7%

Value ($000) $3,862 Shares 481,000 Est. Cost $9.79 Unrealized 0.0%

NGNE NEUROGENE INC 0.7%

Value ($000) $3,548 Shares 303,000 Est. Cost $37.29 Unrealized -53.4%

BBOT HELIX ACQUISITION CORP II 0.5%

Value ($000) $2,825 Shares 250,000 Est. Cost $10.35 Unrealized +3.8%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
—	NUVATION BIO INC	27,330,800	$48,102	9.3%	$1.77	—	*W EXP 02/10/202	67080N119
APLS	APELLIS PHARMACEUTICALS INC	2,094,000	$45,796	8.9%	$47.09	-41.3%	COM	03753U106
DNTH	DIANTHUS THERAPEUTICS INC	2,341,667	$42,478	8.2%	$20.54	+7.3%	COM	252828108
AVBP	ARRIVENT BIOPHARMA INC	2,059,387	$38,078	7.4%	$20.73	+18.1%	COM	04272N102
TRVI	TREVI THERAPEUTICS INC	3,322,000	$20,895	4.0%	$4.77	0.0%	COM	89532M101
CNTA	CENTESSA PHARMACEUTICALS PLC	1,425,000	$20,492	4.0%	$7.34	—	SPONSORED ADS	152309100
GOSS	GOSSAMER BIO INC	18,350,000	$20,185	3.9%	$1.89	-39.0%	COM	38341P102
OCUL	OCULAR THERAPEUTIX INC	2,425,000	$17,775	3.4%	$7.10	+8.3%	COM	67576A100
—	MIND MEDICINE MINDMED INC	3,018,000	$17,655	3.4%	$8.34	—	COM NEW	60255C885
COGT	COGENT BIOSCIENCES INC	2,763,000	$16,550	3.2%	$9.86	-20.5%	COM	19240Q201
KALV	KALVISTA PHARMACEUTICALS INC	1,370,000	$15,810	3.1%	$10.36	-1.5%	COM	483497103
TSHA	TAYSHA GENE THERAPIES INC	10,700,000	$14,873	2.9%	$2.19	-23.6%	COM SHS	877619106
NUVB	NUVATION BIO INC	7,900,000	$13,904	2.7%	$2.99	-24.0%	COM CL A	67080N101
—	VERONA PHARMA PLC	217,264	$13,794	2.7%	$17.59	—	SPONSORED ADS	925050106
—	TOURMALINE BIO INC	905,000	$13,765	2.7%	$15.21	—	COM	89157D105
—	MERUS N V	308,000	$12,964	2.5%	$42.05	—	COM	N5749R100
PHVS	PHARVARIS N V	769,815	$12,086	2.3%	$18.74	-10.0%	COM	N69605108
MLTX	MOONLAKE IMMUNOTHERAPEUTICS	296,000	$11,565	2.2%	$43.09	0.0%	CLASS A ORD	61559X104
SNDX	SYNDAX PHARMACEUTICALS INC	904,000	$11,106	2.1%	$17.11	-17.6%	COM	87164F105
ATYR	ATYR PHARMA INC	3,552,000	$10,727	2.1%	$3.49	+4.5%	COM NEW	002120202
SRRK	SCHOLAR ROCK HLDG CORP	329,000	$10,577	2.0%	$32.56	+18.1%	COM	80706P103
VSTM	VERASTEM INC	1,720,000	$10,372	2.0%	$6.11	0.0%	COM NEW	92337C203
CNTA	CENTESSA PHARMACEUTICALS PLC	600,000	$8,628	1.7%	$7.34	—	Put	152309100
—	REGULUS THERAPEUTICS INC	4,637,076	$8,115	1.6%	$1.76	—	COM	75915K309
SPRY	ARS PHARMACEUTICALS INC	625,000	$7,863	1.5%	$12.03	0.0%	COM	82835W108
ABVX	ABIVAX SA	1,230,000	$7,688	1.5%	$6.25	—	SPONSORED ADS	00370M103
ERAS	ERASCA INC	5,136,795	$7,037	1.4%	$2.74	-37.4%	COM	29479A108
VRDN	VIRIDIAN THERAPEUTICS INC	450,000	$6,066	1.2%	$22.43	-24.1%	COM	92790C104
CRBP	CORBUS PHARMACEUTICALS HLDGS	1,115,000	$5,921	1.1%	$40.87	-78.4%	COM NEW	21833P301
—	UNICYCIVE THERAPEUTICS INC	10,000,000	$5,749	1.1%	$0.46	—	COM	90466Y103
MAZE	MAZE THERAPEUTICS INC	468,000	$5,153	1.0%	$12.04	0.0%	COM	578784100
CATX	PERSPECTIVE THERAPEUTICS INC	2,250,000	$4,793	0.9%	$12.05	-75.1%	COM NEW	46489V302
KLRS	KALARIS THERAPEUTICS INC	481,000	$3,862	0.7%	$9.79	0.0%	COM	482929106
NGNE	NEUROGENE INC	303,000	$3,548	0.7%	$37.29	-53.4%	COM	64135M105
BBOT	HELIX ACQUISITION CORP II	250,000	$2,825	0.5%	$10.35	+3.8%	CL A ORD SHS	G4444H101