Octagon Capital Advisors LP Quant / Systematic

CIK: 0001839435 · Show all filings

Period: Q2 2025 (← Previous) (Next →)

Filing Date: Aug 14, 2025

Total Value ($000): $455,625 (100.0% shares, 0.0% debt)

Holdings (30)

DNTH DIANTHUS THERAPEUTICS INC 9.6%

Value ($000) $43,625 Shares 2,341,667 Est. Cost $20.54 Unrealized -8.6%

AVBP ARRIVENT BIOPHARMA INC 9.3%

Value ($000) $42,366 Shares 1,946,054 Est. Cost $20.73 Unrealized +0.2%

— VERONA PHARMA PLC 7.0%

Value ($000) $31,873 Shares 337,000 Est. Cost $44.94 Unrealized —

TSHA TAYSHA GENE THERAPIES INC 6.4%

Value ($000) $29,089 Shares 12,592,500 Est. Cost $2.19 Unrealized -0.6%

SPRY ARS PHARMACEUTICALS INC 5.2%

Value ($000) $23,558 Shares 1,350,000 Est. Cost $13.32 Unrealized +8.3%

GOSS GOSSAMER BIO INC 5.0%

Value ($000) $22,571 Shares 18,350,000 Est. Cost $1.89 Unrealized -42.4%

OCUL OCULAR THERAPEUTIX INC 4.9%

Value ($000) $22,504 Shares 2,425,000 Est. Cost $7.10 Unrealized +10.3%

— MERUS N V 4.5%

Value ($000) $20,461 Shares 389,000 Est. Cost $44.25 Unrealized —

TRVI TREVI THERAPEUTICS INC 4.4%

Value ($000) $20,086 Shares 3,672,000 Est. Cost $4.91 Unrealized +26.7%

COGT COGENT BIOSCIENCES INC 4.4%

Value ($000) $19,838 Shares 2,763,000 Est. Cost $9.86 Unrealized -43.8%

ATYR ATYR PHARMA INC 4.3%

Value ($000) $19,367 Shares 3,820,000 Est. Cost $3.52 Unrealized +11.7%

APLS APELLIS PHARMACEUTICALS INC 3.4%

Value ($000) $15,640 Shares 903,500 Est. Cost $47.09 Unrealized -60.7%

NUVB NUVATION BIO INC 3.3%

Value ($000) $14,998 Shares 7,691,334 Est. Cost $2.99 Unrealized -30.4%

— TOURMALINE BIO INC 3.2%

Value ($000) $14,471 Shares 905,000 Est. Cost $15.21 Unrealized —

KALV KALVISTA PHARMACEUTICALS INC 3.2%

Value ($000) $14,395 Shares 1,273,333 Est. Cost $10.36 Unrealized +18.0%

— MIND MEDICINE MINDMED INC 3.0%

Value ($000) $13,824 Shares 2,130,000 Est. Cost $8.34 Unrealized —

CNTA CENTESSA PHARMACEUTICALS PLC 3.0%

Value ($000) $13,534 Shares 1,030,000 Est. Cost $7.34 Unrealized —

PHVS PHARVARIS N V 2.6%

Value ($000) $11,838 Shares 672,595 Est. Cost $18.74 Unrealized -14.0%

KYMR KYMERA THERAPEUTICS INC 2.5%

Value ($000) $11,608 Shares 266,000 Est. Cost $34.43 Unrealized 0.0%

ABVX ABIVAX SA 2.1%

Value ($000) $9,693 Shares 1,267,000 Est. Cost $6.29 Unrealized —

DBVT DBV TECHNOLOGIES S A 2.0%

Value ($000) $9,315 Shares 1,018,021 Est. Cost $9.15 Unrealized —

CRBP CORBUS PHARMACEUTICALS HLDGS 1.7%

Value ($000) $7,694 Shares 1,115,000 Est. Cost $40.87 Unrealized -82.2%

MLTX MOONLAKE IMMUNOTHERAPEUTICS 1.5%

Value ($000) $6,986 Shares 148,000 Est. Cost $43.09 Unrealized -5.5%

UNCY UNICYCIVE THERAPEUTICS INC 1.0%

Value ($000) $4,770 Shares 1,000,000 Est. Cost $6.18 Unrealized 0.0%

NGNE NEUROGENE INC 1.0%

Value ($000) $4,530 Shares 303,000 Est. Cost $37.29 Unrealized -57.9%

BBOT HELIX ACQUISITION CORP II 0.6%

Value ($000) $2,663 Shares 250,000 Est. Cost $10.35 Unrealized +4.5%

MAZE MAZE THERAPEUTICS INC 0.5%

Value ($000) $2,180 Shares 177,667 Est. Cost $12.04 Unrealized -13.6%

KLRS KALARIS THERAPEUTICS INC 0.2%

Value ($000) $961 Shares 360,000 Est. Cost $9.79 Unrealized -53.9%

ERAS ERASCA INC 0.2%

Value ($000) $889 Shares 700,000 Est. Cost $2.74 Unrealized -51.2%

— NUVATION BIO INC 0.1%

Value ($000) $301 Shares 154,112 Est. Cost $1.77 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
DNTH	DIANTHUS THERAPEUTICS INC	2,341,667	$43,625	9.6%	$20.54	-8.6%	COM	252828108
AVBP	ARRIVENT BIOPHARMA INC	1,946,054	$42,366	9.3%	$20.73	+0.2%	COM	04272N102
—	VERONA PHARMA PLC	337,000	$31,873	7.0%	$44.94	—	SPONSORED ADS	925050106
TSHA	TAYSHA GENE THERAPIES INC	12,592,500	$29,089	6.4%	$2.19	-0.6%	COM SHS	877619106
SPRY	ARS PHARMACEUTICALS INC	1,350,000	$23,558	5.2%	$13.32	+8.3%	COM	82835W108
GOSS	GOSSAMER BIO INC	18,350,000	$22,571	5.0%	$1.89	-42.4%	COM	38341P102
OCUL	OCULAR THERAPEUTIX INC	2,425,000	$22,504	4.9%	$7.10	+10.3%	COM	67576A100
—	MERUS N V	389,000	$20,461	4.5%	$44.25	—	COM	N5749R100
TRVI	TREVI THERAPEUTICS INC	3,672,000	$20,086	4.4%	$4.91	+26.7%	COM	89532M101
COGT	COGENT BIOSCIENCES INC	2,763,000	$19,838	4.4%	$9.86	-43.8%	COM	19240Q201
ATYR	ATYR PHARMA INC	3,820,000	$19,367	4.3%	$3.52	+11.7%	COM NEW	002120202
APLS	APELLIS PHARMACEUTICALS INC	903,500	$15,640	3.4%	$47.09	-60.7%	COM	03753U106
NUVB	NUVATION BIO INC	7,691,334	$14,998	3.3%	$2.99	-30.4%	COM CL A	67080N101
—	TOURMALINE BIO INC	905,000	$14,471	3.2%	$15.21	—	COM	89157D105
KALV	KALVISTA PHARMACEUTICALS INC	1,273,333	$14,395	3.2%	$10.36	+18.0%	COM	483497103
—	MIND MEDICINE MINDMED INC	2,130,000	$13,824	3.0%	$8.34	—	COM NEW	60255C885
CNTA	CENTESSA PHARMACEUTICALS PLC	1,030,000	$13,534	3.0%	$7.34	—	SPONSORED ADS	152309100
PHVS	PHARVARIS N V	672,595	$11,838	2.6%	$18.74	-14.0%	COM	N69605108
KYMR	KYMERA THERAPEUTICS INC	266,000	$11,608	2.5%	$34.43	0.0%	COM	501575104
ABVX	ABIVAX SA	1,267,000	$9,693	2.1%	$6.29	—	SPONSORED ADS	00370M103
DBVT	DBV TECHNOLOGIES S A	1,018,021	$9,315	2.0%	$9.15	—	SPONSORED ADS	23306J309
CRBP	CORBUS PHARMACEUTICALS HLDGS	1,115,000	$7,694	1.7%	$40.87	-82.2%	COM NEW	21833P301
MLTX	MOONLAKE IMMUNOTHERAPEUTICS	148,000	$6,986	1.5%	$43.09	-5.5%	CLASS A ORD	61559X104
UNCY	UNICYCIVE THERAPEUTICS INC	1,000,000	$4,770	1.0%	$6.18	0.0%	COM NEW	90466Y202
NGNE	NEUROGENE INC	303,000	$4,530	1.0%	$37.29	-57.9%	COM	64135M105
BBOT	HELIX ACQUISITION CORP II	250,000	$2,663	0.6%	$10.35	+4.5%	CL A ORD SHS	G4444H101
MAZE	MAZE THERAPEUTICS INC	177,667	$2,180	0.5%	$12.04	-13.6%	COM	578784100
KLRS	KALARIS THERAPEUTICS INC	360,000	$961	0.2%	$9.79	-53.9%	COM	482929106
ERAS	ERASCA INC	700,000	$889	0.2%	$2.74	-51.2%	COM	29479A108
—	NUVATION BIO INC	154,112	$301	0.1%	$1.77	—	*W EXP 02/10/202	67080N119