Catalio Capital Management, LP Quant / Systematic

CIK: 0001958125 · Show all filings

Period: Q3 2025 (← Previous) (Next →)

Filing Date: Nov 14, 2025

Total Value ($000): $540,930 (100.0% shares, 0.0% debt)

Holdings (38)

LLY ELI LILLY & CO 8.1%

Value ($000) $43,778 Shares 57,376 Est. Cost $793.52 Unrealized -6.5%

ABBV ABBVIE INC 6.6%

Value ($000) $35,850 Shares 154,834 Est. Cost $201.95 Unrealized 0.0%

BBIO BRIDGEBIO PHARMA INC 6.0%

Value ($000) $32,345 Shares 622,729 Est. Cost $26.37 Unrealized +85.0%

ISRG INTUITIVE SURGICAL INC 5.9%

Value ($000) $31,907 Shares 71,343 Est. Cost $513.00 Unrealized -6.5%

ASND ASCENDIS PHARMA A/S 5.3%

Value ($000) $28,818 Shares 144,954 Est. Cost $137.67 Unrealized —

SLNO SOLENO THERAPEUTICS INC 5.2%

Value ($000) $28,273 Shares 418,245 Est. Cost $64.77 Unrealized +14.5%

DNTH DIANTHUS THERAPEUTICS INC 4.9%

Value ($000) $26,271 Shares 667,615 Est. Cost $25.71 Unrealized -0.6%

BSX BOSTON SCIENTIFIC CORP 4.7%

Value ($000) $25,674 Shares 262,972 Est. Cost $101.49 Unrealized +2.0%

SNDX SYNDAX PHARMACEUTICALS INC 4.6%

Value ($000) $24,842 Shares 1,614,717 Est. Cost $13.56 Unrealized -3.5%

CYTK CYTOKINETICS INC 4.6%

Value ($000) $24,819 Shares 451,581 Est. Cost $50.21 Unrealized -18.0%

NTRA NATERA INC 4.4%

Value ($000) $23,883 Shares 148,369 Est. Cost $156.65 Unrealized +1.0%

REGN REGENERON PHARMACEUTICALS 3.7%

Value ($000) $19,873 Shares 35,344 Est. Cost $564.28 Unrealized 0.0%

GPCR STRUCTURE THERAPEUTICS INC 3.4%

Value ($000) $18,251 Shares 651,810 Est. Cost $25.23 Unrealized —

QURE UNIQURE NV 3.1%

Value ($000) $16,515 Shares 282,940 Est. Cost $8.63 Unrealized +110.3%

IRON DISC MEDICINE INC 2.6%

Value ($000) $14,308 Shares 216,527 Est. Cost $57.71 Unrealized +3.1%

ABVX ABIVAX SA 2.5%

Value ($000) $13,766 Shares 162,141 Est. Cost $84.90 Unrealized —

SUPN SUPERNUS PHARMACEUTICALS INC 2.5%

Value ($000) $13,720 Shares 287,090 Est. Cost $40.27 Unrealized 0.0%

EXAS EXACT SCIENCES CORP 2.5%

Value ($000) $13,622 Shares 248,987 Est. Cost $49.96 Unrealized 0.0%

PHAT PHATHOM PHARMACEUTICALS INC 2.5%

Value ($000) $13,283 Shares 1,128,521 Est. Cost $7.47 Unrealized +38.2%

ADPT ADAPTIVE BIOTECHNOLOGIES COR 2.4%

Value ($000) $13,238 Shares 884,890 Est. Cost $8.47 Unrealized +43.8%

RNAM AVIDITY BIOSCIENCES INC 2.1%

Value ($000) $11,470 Shares 263,256 Est. Cost $40.43 Unrealized 0.0%

ADMA ADMA BIOLOGICS INC 1.9%

Value ($000) $10,035 Shares 684,508 Est. Cost $19.85 Unrealized -13.6%

RARE ULTRAGENYX PHARMACEUTICAL IN 1.6%

Value ($000) $8,761 Shares 291,262 Est. Cost $34.43 Unrealized -12.9%

GUTS FRACTYL HEALTH INC 1.5%

Value ($000) $8,291 Shares 5,214,236 Est. Cost $1.34 Unrealized -3.2%

GRAL GRAIL INC 1.5%

Value ($000) $8,156 Shares 137,928 Est. Cost $38.21 Unrealized 0.0%

TARA PROTARA THERAPEUTICS INC 1.2%

Value ($000) $6,528 Shares 1,500,793 Est. Cost $3.30 Unrealized -2.0%

SEPN SEPTERNA INC 1.0%

Value ($000) $5,537 Shares 294,360 Est. Cost $23.65 Unrealized -44.5%

— CIDARA THERAPEUTICS INC 0.9%

Value ($000) $5,107 Shares 53,333 Est. Cost $95.76 Unrealized —

KYTX KYVERNA THERAPEUTICS INC 0.7%

Value ($000) $3,521 Shares 586,909 Est. Cost $4.79 Unrealized -16.6%

ELDN ELEDON PHARMACEUTICALS INC 0.5%

Value ($000) $2,748 Shares 1,061,132 Est. Cost $2.92 Unrealized 0.0%

OM OUTSET MED INC 0.3%

Value ($000) $1,670 Shares 118,279 Est. Cost $11.92 Unrealized +30.8%

MGX METAGENOMI INC 0.2%

Value ($000) $1,254 Shares 528,993 Est. Cost $2.41 Unrealized -15.9%

— ATAI LIFE SCIENCES NV 0.2%

Value ($000) $1,041 Shares 196,858 Est. Cost $1.33 Unrealized —

HYPR HYPERFINE INC 0.2%

Value ($000) $993 Shares 684,541 Est. Cost $0.96 Unrealized +21.4%

MLTX MOONLAKE IMMUNOTHERAPEUTICS 0.2%

Value ($000) $955 Shares 133,131 Est. Cost $42.39 Unrealized +22.9%

KPTI KARYOPHARM THERAPEUTICS INC 0.2%

Value ($000) $935 Shares 142,984 Est. Cost $8.54 Unrealized -37.0%

PVLA PALVELLA THERAPEUTICS INC NE 0.1%

Value ($000) $753 Shares 12,010 Est. Cost $44.59 Unrealized 0.0%

SNSE SENSEI BIOTHERAPEUTICS INC 0.0%

Value ($000) $139 Shares 14,718 Est. Cost $7.18 Unrealized +15.6%

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
LLY	ELI LILLY & CO	57,376	$43,778	8.1%	$793.52	-6.5%	COM	532457108
ABBV	ABBVIE INC	154,834	$35,850	6.6%	$201.95	0.0%	COM	00287Y109
BBIO	BRIDGEBIO PHARMA INC	622,729	$32,345	6.0%	$26.37	+85.0%	COM	10806X102
ISRG	INTUITIVE SURGICAL INC	71,343	$31,907	5.9%	$513.00	-6.5%	COM NEW	46120E602
ASND	ASCENDIS PHARMA A/S	144,954	$28,818	5.3%	$137.67	—	SPONSORED ADR	04351P101
SLNO	SOLENO THERAPEUTICS INC	418,245	$28,273	5.2%	$64.77	+14.5%	COM	834203309
DNTH	DIANTHUS THERAPEUTICS INC	667,615	$26,271	4.9%	$25.71	-0.6%	COM	252828108
BSX	BOSTON SCIENTIFIC CORP	262,972	$25,674	4.7%	$101.49	+2.0%	COM	101137107
SNDX	SYNDAX PHARMACEUTICALS INC	1,614,717	$24,842	4.6%	$13.56	-3.5%	COM	87164F105
CYTK	CYTOKINETICS INC	451,581	$24,819	4.6%	$50.21	-18.0%	COM NEW	23282W605
NTRA	NATERA INC	148,369	$23,883	4.4%	$156.65	+1.0%	COM	632307104
REGN	REGENERON PHARMACEUTICALS	35,344	$19,873	3.7%	$564.28	0.0%	COM	75886F107
GPCR	STRUCTURE THERAPEUTICS INC	651,810	$18,251	3.4%	$25.23	—	SPONSORED ADS	86366E106
QURE	UNIQURE NV	282,940	$16,515	3.1%	$8.63	+110.3%	SHS	N90064101
IRON	DISC MEDICINE INC	216,527	$14,308	2.6%	$57.71	+3.1%	COM	254604101
ABVX	ABIVAX SA	162,141	$13,766	2.5%	$84.90	—	SPONSORED ADS	00370M103
SUPN	SUPERNUS PHARMACEUTICALS INC	287,090	$13,720	2.5%	$40.27	0.0%	COM	868459108
EXAS	EXACT SCIENCES CORP	248,987	$13,622	2.5%	$49.96	0.0%	COM	30063P105
PHAT	PHATHOM PHARMACEUTICALS INC	1,128,521	$13,283	2.5%	$7.47	+38.2%	COM	71722W107
ADPT	ADAPTIVE BIOTECHNOLOGIES COR	884,890	$13,238	2.4%	$8.47	+43.8%	COM	00650F109
RNAM	AVIDITY BIOSCIENCES INC	263,256	$11,470	2.1%	$40.43	0.0%	COM	05370A108
ADMA	ADMA BIOLOGICS INC	684,508	$10,035	1.9%	$19.85	-13.6%	COM	000899104
RARE	ULTRAGENYX PHARMACEUTICAL IN	291,262	$8,761	1.6%	$34.43	-12.9%	COM	90400D108
GUTS	FRACTYL HEALTH INC	5,214,236	$8,291	1.5%	$1.34	-3.2%	COM	35168W103
GRAL	GRAIL INC	137,928	$8,156	1.5%	$38.21	0.0%	COM	384747101
TARA	PROTARA THERAPEUTICS INC	1,500,793	$6,528	1.2%	$3.30	-2.0%	COM STK	74365U107
SEPN	SEPTERNA INC	294,360	$5,537	1.0%	$23.65	-44.5%	COM	81734D104
—	CIDARA THERAPEUTICS INC	53,333	$5,107	0.9%	$95.76	—	COM NEW	171757206
KYTX	KYVERNA THERAPEUTICS INC	586,909	$3,521	0.7%	$4.79	-16.6%	COM	501976104
ELDN	ELEDON PHARMACEUTICALS INC	1,061,132	$2,748	0.5%	$2.92	0.0%	COM	28617K101
OM	OUTSET MED INC	118,279	$1,670	0.3%	$11.92	+30.8%	COM NEW	690145206
MGX	METAGENOMI INC	528,993	$1,254	0.2%	$2.41	-15.9%	COM	59102M104
—	ATAI LIFE SCIENCES NV	196,858	$1,041	0.2%	$1.33	—	SHS	N0731H103
HYPR	HYPERFINE INC	684,541	$993	0.2%	$0.96	+21.4%	COM CL A	44916K106
MLTX	MOONLAKE IMMUNOTHERAPEUTICS	133,131	$955	0.2%	$42.39	+22.9%	CLASS A ORD	61559X104
KPTI	KARYOPHARM THERAPEUTICS INC	142,984	$935	0.2%	$8.54	-37.0%	COM NEW	48576U205
PVLA	PALVELLA THERAPEUTICS INC NE	12,010	$753	0.1%	$44.59	0.0%	COM	697947109
SNSE	SENSEI BIOTHERAPEUTICS INC	14,718	$139	0.0%	$7.18	+15.6%	COM NEW	81728A207