CORBUS PHARMACEUTICALS HLDGS

Institution	Shares	Value ($000)
Stonepine Capital Management, LLC	389,916	$3,174
B. Riley Financial, Inc.	38,714	$315
SHERBROOKE PARK ADVISERS LLC	15,410	$125
683 Capital Management, LLC	85,543	$696
Persistent Asset Partners Ltd	6,587	$54
Pale Fire Capital SE	18,650	$152
Jump Financial, LLC	60,300	$491
CITADEL ADVISORS LLC	843,193	$6,864
Caption Management, LLC	56,066	$456
Laurion Capital Management LP	18,600	$151
Quadrature Capital Ltd	29,889	$243
Point72 Asset Management, L.P.	75,134	$612
OMERS ADMINISTRATION Corp	30,000	$244
DIMENSIONAL FUND ADVISORS LP	77,354	$630
Engineers Gate Manager LP	17,143	$140
Brevan Howard Capital Management LP	18,795	$153
Hudson Bay Capital Management LP	17,089	$139
Walleye Trading LLC	15,851	$129
Qube Research & Technologies Ltd	15,914	$130
AMERICAN CENTURY COMPANIES INC	13,411	$109

Increased Positions (23)

Prosight Management, LP

Value ($000) $5,567 (+28.1%) Shares 683,872 (+99.1%)

ADAR1 Capital Management, LLC

Value ($000) $2,334 (+1709.2%) Shares 286,781 (+2711.6%)

ORBIMED ADVISORS LLC

Value ($000) $13,002 (-12.3%) Shares 1,597,287 (+36.3%)

ARMISTICE CAPITAL, LLC

Value ($000) $4,363 (+79.6%) Shares 536,000 (+179.2%)

abrdn plc

Value ($000) $10,759 (+351.8%) Shares 1,321,750 (+602.2%)

RENAISSANCE TECHNOLOGIES LLC

Value ($000) $2,884 (+112.7%) Shares 354,300 (+230.5%)

BALYASNY ASSET MANAGEMENT L.P.

Value ($000) $1,085 (+266.3%) Shares 133,311 (+469.3%)

Assenagon Asset Management S.A.

Value ($000) $1,530 (+41.7%) Shares 187,956 (+120.2%)

MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.

Value ($000) $1,482 (+36.5%) Shares 182,062 (+112.1%)

VANGUARD GROUP INC

Value ($000) $6,996 (-9.6%) Shares 859,407 (+40.4%)

SUSQUEHANNA INTERNATIONAL GROUP, LLP

Value ($000) $1,855 (+111.7%) Shares 227,826 (+229.0%)

AMERIPRISE FINANCIAL INC

Value ($000) $1,105 (+25.4%) Shares 135,730 (+94.9%)

Trexquant Investment LP

Value ($000) $222 (+44.3%) Shares 27,275 (+124.2%)

GEODE CAPITAL MANAGEMENT, LLC

Value ($000) $1,391 (-13.9%) Shares 170,873 (+33.8%)

BlackRock, Inc.

Value ($000) $2,182 (-24.0%) Shares 268,046 (+18.1%)

AlphaQuest LLC

Value ($000) $186 (-22.4%) Shares 22,906 (+20.6%)

D. E. Shaw & Co., Inc.

Value ($000) $234 (+74.4%) Shares 28,794 (+171.0%)

NORTHERN TRUST CORP

Value ($000) $339 (-1.5%) Shares 41,694 (+53.1%)

GOLDMAN SACHS GROUP INC

Value ($000) $386 (-8.5%) Shares 47,438 (+42.2%)

ROYAL BANK OF CANADA

Value ($000) $135 (-30.1%) Shares 16,500 (+8.2%)

Institution	Prev Shares	Curr Shares	Change
Prosight Management, LP	343,400	683,872	+340,472 (+99.1%)
ADAR1 Capital Management, LLC	10,200	286,781	+276,581 (+2711.6%)
ORBIMED ADVISORS LLC	1,172,287	1,597,287	+425,000 (+36.3%)
ARMISTICE CAPITAL, LLC	192,000	536,000	+344,000 (+179.2%)
abrdn plc	188,231	1,321,750	+1,133,519 (+602.2%)
RENAISSANCE TECHNOLOGIES LLC	107,200	354,300	+247,100 (+230.5%)
BALYASNY ASSET MANAGEMENT L.P.	23,418	133,311	+109,893 (+469.3%)
Assenagon Asset Management S.A.	85,347	187,956	+102,609 (+120.2%)
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	85,826	182,062	+96,236 (+112.1%)
VANGUARD GROUP INC	612,030	859,407	+247,377 (+40.4%)
SUSQUEHANNA INTERNATIONAL GROUP, LLP	69,246	227,826	+158,580 (+229.0%)
AMERIPRISE FINANCIAL INC	69,625	135,730	+66,105 (+94.9%)
Trexquant Investment LP	12,165	27,275	+15,110 (+124.2%)
GEODE CAPITAL MANAGEMENT, LLC	127,731	170,873	+43,142 (+33.8%)
BlackRock, Inc.	226,898	268,046	+41,148 (+18.1%)
AlphaQuest LLC	18,994	22,906	+3,912 (+20.6%)
D. E. Shaw & Co., Inc.	10,627	28,794	+18,167 (+171.0%)
NORTHERN TRUST CORP	27,231	41,694	+14,463 (+53.1%)
GOLDMAN SACHS GROUP INC	33,352	47,438	+14,086 (+42.2%)
ROYAL BANK OF CANADA	15,253	16,500	+1,247 (+8.2%)

Decreased Positions (24)

Exome Asset Management LLC

Value ($000) $1,136 (-61.0%) Shares 139,543 (-39.3%)

Octagon Capital Advisors LP

Value ($000) $7,774 (-44.9%) Shares 955,000 (-14.3%)

Velan Capital Investment Management LP

Value ($000) $106 (-86.3%) Shares 13,000 (-78.7%)

Cormorant Asset Management, LP

Value ($000) $19,088 (-36.5%) Shares 2,344,971 (-1.3%)

HealthInvest Partners AB

Value ($000) $873 (+270.2%) Shares 107,255 (-38.9%)

PRELUDE CAPITAL MANAGEMENT, LLC

Value ($000) $145 (-82.9%) Shares 17,781 (-73.5%)

MORGAN STANLEY

Value ($000) $182 (-90.7%) Shares 22,381 (-85.5%)

MILLENNIUM MANAGEMENT LLC

Value ($000) $302 (-82.5%) Shares 37,065 (-72.8%)

BANK OF AMERICA CORP /DE/

Value ($000) $0 (-100.0%) Shares 26 (-100.0%)

BARCLAYS PLC

Value ($000) $120 (-84.9%) Shares 14,758 (-61.6%)

JANE STREET GROUP, LLC

Value ($000) $228 (-68.9%) Shares 28,064 (-51.7%)

MARSHALL WACE, LLP

Value ($000) $631 (-51.3%) Shares 77,546 (-24.4%)

TWO SIGMA INVESTMENTS, LP

Value ($000) $102 (-69.6%) Shares 12,480 (-52.8%)

UBS Group AG

Value ($000) $417 (-44.6%) Shares 51,209 (-13.9%)

Mariner, LLC

Value ($000) $139 (-47.2%) Shares 17,086 (-18.0%)

Avanza Fonder AB

Value ($000) $40 (-56.2%) Shares 4,868 (-31.9%)

BNP PARIBAS ARBITRAGE, SA

Value ($000) $0 (-95.1%) Shares 39 (-92.4%)

FMR LLC

Value ($000) $9 (-48.1%) Shares 1,129 (-19.4%)

SRS Capital Advisors, Inc.

Value ($000) $0 (-98.6%) Shares 3 (-97.8%)

MAI Capital Management

Value ($000) $1 (-56.2%) Shares 126 (-31.9%)

Institution	Prev Shares	Curr Shares	Change
Exome Asset Management LLC	229,962	139,543	-90,419 (-39.3%)
Octagon Capital Advisors LP	1,115,000	955,000	-160,000 (-14.3%)
Velan Capital Investment Management LP	61,000	13,000	-48,000 (-78.7%)
Cormorant Asset Management, LP	2,375,000	2,344,971	-30,029 (-1.3%)
HealthInvest Partners AB	175,582	107,255	-68,327 (-38.9%)
PRELUDE CAPITAL MANAGEMENT, LLC	66,984	17,781	-49,203 (-73.5%)
MORGAN STANLEY	154,842	22,381	-132,461 (-85.5%)
MILLENNIUM MANAGEMENT LLC	136,429	37,065	-99,364 (-72.8%)
BANK OF AMERICA CORP /DE/	54,661	26	-54,635 (-100.0%)
BARCLAYS PLC	38,462	14,758	-23,704 (-61.6%)
JANE STREET GROUP, LLC	58,151	28,064	-30,087 (-51.7%)
MARSHALL WACE, LLP	102,509	77,546	-24,963 (-24.4%)
TWO SIGMA INVESTMENTS, LP	26,457	12,480	-13,977 (-52.8%)
UBS Group AG	59,496	51,209	-8,287 (-13.9%)
Mariner, LLC	20,840	17,086	-3,754 (-18.0%)
Avanza Fonder AB	7,150	4,868	-2,282 (-31.9%)
BNP PARIBAS ARBITRAGE, SA	514	39	-475 (-92.4%)
FMR LLC	1,400	1,129	-271 (-19.4%)
SRS Capital Advisors, Inc.	139	3	-136 (-97.8%)
MAI Capital Management	185	126	-59 (-31.9%)

Exited Positions (8)

SUPERSTRING CAPITAL MANAGEMENT LP

Value ($000) $729 Shares 57,644

HighVista Strategies LLC

Value ($000) $1,493 Shares 118,027

TANG CAPITAL MANAGEMENT LLC

Value ($000) $1,613 Shares 127,520

Catalyst Funds Management Pty Ltd

Value ($000) $128 Shares 10,149

Baker Avenue Asset Management, LP

Value ($000) $306 Shares 24,191

IFP Advisors, Inc

Value ($000) $0 Shares 19

SIMPLEX TRADING, LLC

Value ($000) $0 Shares 17,950

Advisory Services Network, LLC

Value ($000) $0 Shares 14

Institution	Prev Shares	Prev Value ($000)
SUPERSTRING CAPITAL MANAGEMENT LP	57,644	$729
HighVista Strategies LLC	118,027	$1,493
TANG CAPITAL MANAGEMENT LLC	127,520	$1,613
Catalyst Funds Management Pty Ltd	10,149	$128
Baker Avenue Asset Management, LP	24,191	$306
IFP Advisors, Inc	19	$0
SIMPLEX TRADING, LLC	17,950	$0
Advisory Services Network, LLC	14	$0