LEAP THERAPEUTICS INC

Ticker: CYPH CUSIP: 52187K200 Class: COM NEW

Holders for Q4 2025 Position Changes for Q4 2025

Note: Option positions (PUT/CALL) are excluded.

InstitutionSharesValue ($000)
BlackRock, Inc.2,342,174$2,717
VANGUARD GROUP INC2,127,109$2,467
Simplify Asset Management Inc.1,872,322$2,172
SUSQUEHANNA INTERNATIONAL GROUP, LLP557,179$646
GEODE CAPITAL MANAGEMENT, LLC530,192$615
GROUP ONE TRADING, L.P.161,579$187
STATE STREET CORP140,113$163
Texas Capital Bank Wealth Management Services Inc104,200$121
NORTHERN TRUST CORP87,562$102
Key Client Fiduciary Advisors, LLC84,587$98
CITIGROUP INC73,022$85
TWO SIGMA INVESTMENTS, LP72,172$84
SIMPLEX TRADING, LLC67,818$79
Qube Research & Technologies Ltd62,486$72
HighTower Advisors, LLC50,500$59
Sequoia Financial Advisors, LLC48,000$56
Caitong International Asset Management Co., Ltd38,191$44
Toroso Investments, LLC35,314$41
LPL Financial LLC32,764$38
MILLENNIUM MANAGEMENT LLC32,267$37
UBS Group AG31,145$36
Tower Research Capital LLC (TRC)12,605$15
Keystone Financial Group11,712$14
IHT Wealth Management, LLC11,000$13
BLAIR WILLIAM & CO/IL10,000$12
Cetera Investment Advisers10,000$12
ROYAL BANK OF CANADA9,881$11
CNB Bank5,000$6
Farther Finance Advisors, LLC2,058$2
OSAIC HOLDINGS, INC.1,850$2
HUNTINGTON NATIONAL BANK1,000$1
OPTIMA CAPITAL LLC798$1
MORGAN STANLEY486$1
BANK OF AMERICA CORP /DE/453$1
JPMORGAN CHASE & CO227$0
Fortitude Family Office, LLC182$0
Allworth Financial LP135$0
TOMPKINS FINANCIAL CORP120$0
Total (38 institutions)8,628,203$10,008