Casdin Capital, LLC Diversified Active

Location: New York, NY

CIK: 0001534261 · Show all filings

Period: Q3 2023 (← Previous) (Next →)

Filing Date: Nov 14, 2023

Total Value: $904M (100.0% shares, 0.0% debt)

Holdings (40)

SRPT SAREPTA THERAPEUTICS INC 13.6%

Value $122M Shares 1,010,330 Est. Cost $99.50 Unrealized +13.6%

BLFS BIOLIFE SOLUTIONS INC 11.9%

Value $107M Shares 7,780,000 Est. Cost $20.22 Unrealized -22.1%

— EQRX INC 9.7%

Value $87.75M Shares 39,527,669 Est. Cost $6.82 Unrealized —

GPCR STRUCTURE THERAPEUTICS INC 6.9%

Value $61.96M Shares 1,258,166 Est. Cost $33.60 Unrealized —

RLAY RELAY THERAPEUTICS INC 6.4%

Value $58.23M Shares 6,923,574 Est. Cost $24.08 Unrealized -55.3%

RVMD REVOLUTION MEDICINES INC 5.5%

Value $50.1M Shares 1,810,000 Est. Cost $29.92 Unrealized -0.9%

— VERVE THERAPEUTICS INC 4.3%

Value $39.18M Shares 2,954,710 Est. Cost $46.67 Unrealized —

NTLA INTELLIA THERAPEUTICS INC 4.1%

Value $37.25M Shares 1,178,075 Est. Cost $44.50 Unrealized -12.8%

ALNY ALNYLAM PHARMACEUTICALS INC 3.9%

Value $35.42M Shares 200,000 Est. Cost $114.05 Unrealized +67.6%

EXAS EXACT SCIENCES CORP 3.5%

Value $31.34M Shares 459,450 Est. Cost $81.07 Unrealized +4.7%

— SOMALOGIC INC 3.3%

Value $30.12M Shares 12,604,275 Est. Cost $12.23 Unrealized —

PLRX PLIANT THERAPEUTICS INC 3.0%

Value $27.35M Shares 1,577,108 Est. Cost $20.16 Unrealized -14.0%

DNLI DENALI THERAPEUTICS INC 3.0%

Value $26.82M Shares 1,300,000 Est. Cost $29.48 Unrealized -14.0%

— MIRATI THERAPEUTICS INC 2.4%

Value $21.71M Shares 498,427 Est. Cost $44.30 Unrealized —

— BLUEPRINT MEDICINES CORP 2.1%

Value $18.65M Shares 371,378 Est. Cost $3820.05 Unrealized —

TNYA TENAYA THERAPEUTICS INC 1.8%

Value $16.27M Shares 6,381,377 Est. Cost $13.31 Unrealized -68.5%

TNGX TANGO THERAPEUTICS INC 1.6%

Value $14.72M Shares 1,307,349 Est. Cost $5.87 Unrealized +3.8%

BEAM BEAM THERAPEUTICS INC 1.5%

Value $13.71M Shares 570,000 Est. Cost $58.84 Unrealized -54.4%

FDMT 4D MOLECULAR THERAPEUTICS IN 1.5%

Value $13.16M Shares 1,033,811 Est. Cost $17.09 Unrealized -2.1%

WGS GENEDX HOLDINGS CORP 1.2%

Value $11.27M Shares 3,095,511 Est. Cost $7.91 Unrealized -30.8%

ABCL ABCELLERA BIOLOGICS INC 1.2%

Value $10.86M Shares 2,360,129 Est. Cost $10.18 Unrealized -40.2%

PACB PACIFIC BIOSCIENCES CALIF IN 1.0%

Value $8.649M Shares 1,035,859 Est. Cost $11.43 Unrealized 0.0%

RNAM AVIDITY BIOSCIENCES INC 0.9%

Value $7.975M Shares 1,250,000 Est. Cost $12.90 Unrealized -33.2%

— 2SEVENTY BIO INC 0.9%

Value $7.934M Shares 2,023,913 Est. Cost $11.78 Unrealized —

IPSC CENTURY THERAPEUTICS INC 0.7%

Value $6.413M Shares 3,206,380 Est. Cost $25.37 Unrealized -89.5%

MXCT MAXCYTE INC 0.7%

Value $5.897M Shares 1,890,000 Est. Cost $15.08 Unrealized -73.3%

FATE FATE THERAPEUTICS INC 0.5%

Value $4.346M Shares 2,050,000 Est. Cost $17.49 Unrealized -81.1%

ALNY ALNYLAM PHARMACEUTICALS INC 0.4%

Value $3.542M Shares 20,000 Est. Cost $114.05 Unrealized +67.6%

PRME PRIME MEDICINE INC 0.4%

Value $3.503M Shares 367,175 Est. Cost $18.06 Unrealized -28.1%

LAB STANDARD BIOTOOLS INC 0.4%

Value $3.48M Shares 1,200,000 Est. Cost $1.97 Unrealized +32.5%

ILMN ILLUMINA INC 0.4%

Value $3.432M Shares 25,000 Est. Cost $197.84 Unrealized -16.9%

ILMN ILLUMINA INC 0.4%

Value $3.432M Shares 25,000 Est. Cost $197.84 Unrealized -16.9%

SANA SANA BIOTECHNOLOGY INC 0.3%

Value $2.902M Shares 750,000 Est. Cost $5.76 Unrealized -6.7%

GLUE MONTE ROSA THERAPEUTICS INC 0.3%

Value $2.447M Shares 510,882 Est. Cost $20.37 Unrealized -68.4%

ABSI ABSCI CORPORATION 0.1%

Value $1.285M Shares 973,260 Est. Cost $19.41 Unrealized -91.0%

— EXSCIENTIA PLC 0.1%

Value $967K Shares 213,900 Est. Cost $19.76 Unrealized —

CDXS CODEXIS INC 0.1%

Value $567K Shares 300,000 Est. Cost $2.34 Unrealized 0.0%

— SINGULAR GENOMICS SYSTEMS IN 0.1%

Value $504K Shares 1,323,885 Est. Cost $18.57 Unrealized —

LIANY LIANBIO 0.0%

Value $308K Shares 206,415 Est. Cost $6.16 Unrealized —

— KRONOS BIO INC 0.0%

Value $161K Shares 123,839 Est. Cost $29.87 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
SRPT	SAREPTA THERAPEUTICS INC	1,010,330	$122M	13.6%	$99.50	+13.6%	COM	803607100
BLFS	BIOLIFE SOLUTIONS INC	7,780,000	$107M	11.9%	$20.22	-22.1%	COM NEW	09062W204
—	EQRX INC	39,527,669	$87.75M	9.7%	$6.82	—	COM	26886C107
GPCR	STRUCTURE THERAPEUTICS INC	1,258,166	$61.96M	6.9%	$33.60	—	SPONSORED ADS	86366E106
RLAY	RELAY THERAPEUTICS INC	6,923,574	$58.23M	6.4%	$24.08	-55.3%	COM	75943R102
RVMD	REVOLUTION MEDICINES INC	1,810,000	$50.1M	5.5%	$29.92	-0.9%	COM	76155X100
—	VERVE THERAPEUTICS INC	2,954,710	$39.18M	4.3%	$46.67	—	COM	92539P101
NTLA	INTELLIA THERAPEUTICS INC	1,178,075	$37.25M	4.1%	$44.50	-12.8%	COM	45826J105
ALNY	ALNYLAM PHARMACEUTICALS INC	200,000	$35.42M	3.9%	$114.05	+67.6%	COM	02043Q107
EXAS	EXACT SCIENCES CORP	459,450	$31.34M	3.5%	$81.07	+4.7%	COM	30063P105
—	SOMALOGIC INC	12,604,275	$30.12M	3.3%	$12.23	—	CLASS A COM	83444K105
PLRX	PLIANT THERAPEUTICS INC	1,577,108	$27.35M	3.0%	$20.16	-14.0%	COM	729139105
DNLI	DENALI THERAPEUTICS INC	1,300,000	$26.82M	3.0%	$29.48	-14.0%	COM	24823R105
—	MIRATI THERAPEUTICS INC	498,427	$21.71M	2.4%	$44.30	—	COM	60468T105
—	BLUEPRINT MEDICINES CORP	371,378	$18.65M	2.1%	$3820.05	—	COM	09627Y109
TNYA	TENAYA THERAPEUTICS INC	6,381,377	$16.27M	1.8%	$13.31	-68.5%	COM	87990A106
TNGX	TANGO THERAPEUTICS INC	1,307,349	$14.72M	1.6%	$5.87	+3.8%	COM	87583X109
BEAM	BEAM THERAPEUTICS INC	570,000	$13.71M	1.5%	$58.84	-54.4%	COM	07373V105
FDMT	4D MOLECULAR THERAPEUTICS IN	1,033,811	$13.16M	1.5%	$17.09	-2.1%	COM	35104E100
WGS	GENEDX HOLDINGS CORP	3,095,511	$11.27M	1.2%	$7.91	-30.8%	COM CL A	81663L200
ABCL	ABCELLERA BIOLOGICS INC	2,360,129	$10.86M	1.2%	$10.18	-40.2%	COM	00288U106
PACB	PACIFIC BIOSCIENCES CALIF IN	1,035,859	$8.649M	1.0%	$11.43	0.0%	COM	69404D108
RNAM	AVIDITY BIOSCIENCES INC	1,250,000	$7.975M	0.9%	$12.90	-33.2%	COM	05370A108
—	2SEVENTY BIO INC	2,023,913	$7.934M	0.9%	$11.78	—	COMMON STOCK	901384107
IPSC	CENTURY THERAPEUTICS INC	3,206,380	$6.413M	0.7%	$25.37	-89.5%	COM	15673T100
MXCT	MAXCYTE INC	1,890,000	$5.897M	0.7%	$15.08	-73.3%	COM	57777K106
FATE	FATE THERAPEUTICS INC	2,050,000	$4.346M	0.5%	$17.49	-81.1%	COM	31189P102
ALNY	ALNYLAM PHARMACEUTICALS INC	20,000	$3.542M	0.4%	$114.05	+67.6%	Call	02043Q107
PRME	PRIME MEDICINE INC	367,175	$3.503M	0.4%	$18.06	-28.1%	COM	74168J101
LAB	STANDARD BIOTOOLS INC	1,200,000	$3.48M	0.4%	$1.97	+32.5%	COM	34385P108
ILMN	ILLUMINA INC	25,000	$3.432M	0.4%	$197.84	-16.9%	Call	452327109
ILMN	ILLUMINA INC	25,000	$3.432M	0.4%	$197.84	-16.9%	COM	452327109
SANA	SANA BIOTECHNOLOGY INC	750,000	$2.902M	0.3%	$5.76	-6.7%	COM	799566104
GLUE	MONTE ROSA THERAPEUTICS INC	510,882	$2.447M	0.3%	$20.37	-68.4%	COM	61225M102
ABSI	ABSCI CORPORATION	973,260	$1.285M	0.1%	$19.41	-91.0%	COM	00091E109
—	EXSCIENTIA PLC	213,900	$967K	0.1%	$19.76	—	ADS	30223G102
CDXS	CODEXIS INC	300,000	$567K	0.1%	$2.34	0.0%	COM	192005106
—	SINGULAR GENOMICS SYSTEMS IN	1,323,885	$504K	0.1%	$18.57	—	COM	82933R100
LIANY	LIANBIO	206,415	$308K	0.0%	$6.16	—	SPONSORED ADS	53000N108
—	KRONOS BIO INC	123,839	$161K	0.0%	$29.87	—	COM	50107A104