Casdin Capital, LLC Diversified Active

CIK: 0001534261 · Show all filings

Period: Q4 2023 (← Previous) (Next →)

Filing Date: Feb 14, 2024

Total Value ($000): $1,018,739 (100.0% shares, 0.0% debt)

Holdings (38)

RVMD REVOLUTION MEDICINES INC 16.1%

Value ($000) $163,900 Shares 5,714,775 Est. Cost $25.89 Unrealized -7.2%

BLFS BIOLIFE SOLUTIONS INC 13.9%

Value ($000) $141,491 Shares 8,707,165 Est. Cost $19.43 Unrealized -34.3%

SRPT SAREPTA THERAPEUTICS INC 9.5%

Value ($000) $97,057 Shares 1,006,500 Est. Cost $99.50 Unrealized -3.6%

RLAY RELAY THERAPEUTICS INC 8.0%

Value ($000) $81,341 Shares 7,387,943 Est. Cost $23.10 Unrealized -63.5%

GPCR STRUCTURE THERAPEUTICS INC 4.4%

Value ($000) $44,504 Shares 1,091,867 Est. Cost $33.60 Unrealized —

NTLA INTELLIA THERAPEUTICS INC 4.3%

Value ($000) $44,211 Shares 1,450,000 Est. Cost $41.54 Unrealized -30.8%

ILMN ILLUMINA INC 4.3%

Value ($000) $43,582 Shares 313,000 Est. Cost $121.95 Unrealized -5.4%

— VERVE THERAPEUTICS INC 4.1%

Value ($000) $41,947 Shares 3,009,094 Est. Cost $46.08 Unrealized —

ALNY ALNYLAM PHARMACEUTICALS INC 3.7%

Value ($000) $37,325 Shares 195,000 Est. Cost $114.05 Unrealized +49.4%

— SOMALOGIC INC 3.1%

Value ($000) $31,889 Shares 12,604,275 Est. Cost $12.23 Unrealized —

EXAS EXACT SCIENCES CORP 3.1%

Value ($000) $31,072 Shares 420,000 Est. Cost $81.07 Unrealized -19.2%

— BLUEPRINT MEDICINES CORP 3.0%

Value ($000) $30,105 Shares 326,378 Est. Cost $3820.05 Unrealized —

PLRX PLIANT THERAPEUTICS INC 2.8%

Value ($000) $28,561 Shares 1,577,108 Est. Cost $20.16 Unrealized -24.6%

DNLI DENALI THERAPEUTICS INC 2.7%

Value ($000) $27,898 Shares 1,300,000 Est. Cost $29.48 Unrealized -32.8%

FDMT 4D MOLECULAR THERAPEUTICS IN 2.1%

Value ($000) $20,945 Shares 1,033,811 Est. Cost $17.09 Unrealized -23.0%

TNYA TENAYA THERAPEUTICS INC 2.0%

Value ($000) $20,676 Shares 6,381,377 Est. Cost $13.31 Unrealized -83.8%

BEAM BEAM THERAPEUTICS INC 1.4%

Value ($000) $14,372 Shares 528,000 Est. Cost $58.84 Unrealized -57.8%

ABCL ABCELLERA BIOLOGICS INC 1.3%

Value ($000) $13,476 Shares 2,360,129 Est. Cost $10.18 Unrealized -54.5%

TNGX TANGO THERAPEUTICS INC 1.2%

Value ($000) $11,765 Shares 1,188,349 Est. Cost $5.87 Unrealized +47.8%

IPSC CENTURY THERAPEUTICS INC 1.0%

Value ($000) $10,645 Shares 3,206,380 Est. Cost $25.37 Unrealized -92.8%

RNAM AVIDITY BIOSCIENCES INC 1.0%

Value ($000) $10,641 Shares 1,175,750 Est. Cost $12.90 Unrealized -48.2%

NGNE NEUROGENE INC 1.0%

Value ($000) $10,167 Shares 524,616 Est. Cost $14.32 Unrealized 0.0%

PACB PACIFIC BIOSCIENCES CALIF IN 1.0%

Value ($000) $10,162 Shares 1,035,859 Est. Cost $11.43 Unrealized -28.4%

WGS GENEDX HOLDINGS CORP 0.8%

Value ($000) $8,513 Shares 3,095,511 Est. Cost $7.91 Unrealized -70.6%

FATE FATE THERAPEUTICS INC 0.8%

Value ($000) $7,667 Shares 2,050,000 Est. Cost $17.49 Unrealized -86.5%

CDXS CODEXIS INC 0.6%

Value ($000) $6,100 Shares 2,000,000 Est. Cost $2.18 Unrealized -1.3%

— 2SEVENTY BIO INC 0.5%

Value ($000) $5,050 Shares 1,182,623 Est. Cost $11.78 Unrealized —

ABSI ABSCI CORPORATION 0.4%

Value ($000) $4,088 Shares 973,260 Est. Cost $19.41 Unrealized -90.4%

ILMN ILLUMINA INC 0.3%

Value ($000) $3,481 Shares 25,000 Est. Cost $121.95 Unrealized -5.4%

PRME PRIME MEDICINE INC 0.3%

Value ($000) $3,253 Shares 367,175 Est. Cost $18.06 Unrealized -57.4%

SNDX SYNDAX PHARMACEUTICALS INC 0.3%

Value ($000) $3,242 Shares 150,000 Est. Cost $15.37 Unrealized 0.0%

GLUE MONTE ROSA THERAPEUTICS INC 0.3%

Value ($000) $2,886 Shares 510,882 Est. Cost $20.37 Unrealized -80.7%

LAB STANDARD BIOTOOLS INC 0.3%

Value ($000) $2,652 Shares 1,200,000 Est. Cost $1.97 Unrealized +8.2%

— EXSCIENTIA PLC 0.1%

Value ($000) $1,371 Shares 213,900 Est. Cost $19.76 Unrealized —

GPCR STRUCTURE THERAPEUTICS INC 0.1%

Value ($000) $1,019 Shares 25,000 Est. Cost $33.60 Unrealized —

LIANY LIANBIO 0.1%

Value ($000) $923 Shares 206,415 Est. Cost $6.16 Unrealized —

— SINGULAR GENOMICS SYSTEMS IN 0.1%

Value ($000) $609 Shares 1,323,885 Est. Cost $18.57 Unrealized —

— KRONOS BIO INC 0.0%

Value ($000) $155 Shares 123,839 Est. Cost $29.87 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
RVMD	REVOLUTION MEDICINES INC	5,714,775	$163,900	16.1%	$25.89	-7.2%	COM	76155X100
BLFS	BIOLIFE SOLUTIONS INC	8,707,165	$141,491	13.9%	$19.43	-34.3%	COM NEW	09062W204
SRPT	SAREPTA THERAPEUTICS INC	1,006,500	$97,057	9.5%	$99.50	-3.6%	COM	803607100
RLAY	RELAY THERAPEUTICS INC	7,387,943	$81,341	8.0%	$23.10	-63.5%	COM	75943R102
GPCR	STRUCTURE THERAPEUTICS INC	1,091,867	$44,504	4.4%	$33.60	—	SPONSORED ADS	86366E106
NTLA	INTELLIA THERAPEUTICS INC	1,450,000	$44,211	4.3%	$41.54	-30.8%	COM	45826J105
ILMN	ILLUMINA INC	313,000	$43,582	4.3%	$121.95	-5.4%	COM	452327109
—	VERVE THERAPEUTICS INC	3,009,094	$41,947	4.1%	$46.08	—	COM	92539P101
ALNY	ALNYLAM PHARMACEUTICALS INC	195,000	$37,325	3.7%	$114.05	+49.4%	COM	02043Q107
—	SOMALOGIC INC	12,604,275	$31,889	3.1%	$12.23	—	CLASS A COM	83444K105
EXAS	EXACT SCIENCES CORP	420,000	$31,072	3.1%	$81.07	-19.2%	COM	30063P105
—	BLUEPRINT MEDICINES CORP	326,378	$30,105	3.0%	$3820.05	—	COM	09627Y109
PLRX	PLIANT THERAPEUTICS INC	1,577,108	$28,561	2.8%	$20.16	-24.6%	COM	729139105
DNLI	DENALI THERAPEUTICS INC	1,300,000	$27,898	2.7%	$29.48	-32.8%	COM	24823R105
FDMT	4D MOLECULAR THERAPEUTICS IN	1,033,811	$20,945	2.1%	$17.09	-23.0%	COM	35104E100
TNYA	TENAYA THERAPEUTICS INC	6,381,377	$20,676	2.0%	$13.31	-83.8%	COM	87990A106
BEAM	BEAM THERAPEUTICS INC	528,000	$14,372	1.4%	$58.84	-57.8%	COM	07373V105
ABCL	ABCELLERA BIOLOGICS INC	2,360,129	$13,476	1.3%	$10.18	-54.5%	COM	00288U106
TNGX	TANGO THERAPEUTICS INC	1,188,349	$11,765	1.2%	$5.87	+47.8%	COM	87583X109
IPSC	CENTURY THERAPEUTICS INC	3,206,380	$10,645	1.0%	$25.37	-92.8%	COM	15673T100
RNAM	AVIDITY BIOSCIENCES INC	1,175,750	$10,641	1.0%	$12.90	-48.2%	COM	05370A108
NGNE	NEUROGENE INC	524,616	$10,167	1.0%	$14.32	0.0%	COM	64135M105
PACB	PACIFIC BIOSCIENCES CALIF IN	1,035,859	$10,162	1.0%	$11.43	-28.4%	COM	69404D108
WGS	GENEDX HOLDINGS CORP	3,095,511	$8,513	0.8%	$7.91	-70.6%	COM CL A	81663L200
FATE	FATE THERAPEUTICS INC	2,050,000	$7,667	0.8%	$17.49	-86.5%	COM	31189P102
CDXS	CODEXIS INC	2,000,000	$6,100	0.6%	$2.18	-1.3%	COM	192005106
—	2SEVENTY BIO INC	1,182,623	$5,050	0.5%	$11.78	—	COMMON STOCK	901384107
ABSI	ABSCI CORPORATION	973,260	$4,088	0.4%	$19.41	-90.4%	COM	00091E109
ILMN	ILLUMINA INC	25,000	$3,481	0.3%	$121.95	-5.4%	Call	452327109
PRME	PRIME MEDICINE INC	367,175	$3,253	0.3%	$18.06	-57.4%	COM	74168J101
SNDX	SYNDAX PHARMACEUTICALS INC	150,000	$3,242	0.3%	$15.37	0.0%	COM	87164F105
GLUE	MONTE ROSA THERAPEUTICS INC	510,882	$2,886	0.3%	$20.37	-80.7%	COM	61225M102
LAB	STANDARD BIOTOOLS INC	1,200,000	$2,652	0.3%	$1.97	+8.2%	COM	34385P108
—	EXSCIENTIA PLC	213,900	$1,371	0.1%	$19.76	—	ADS	30223G102
GPCR	STRUCTURE THERAPEUTICS INC	25,000	$1,019	0.1%	$33.60	—	Call	86366E106
LIANY	LIANBIO	206,415	$923	0.1%	$6.16	—	SPONSORED ADS	53000N108
—	SINGULAR GENOMICS SYSTEMS IN	1,323,885	$609	0.1%	$18.57	—	COM	82933R100
—	KRONOS BIO INC	123,839	$155	0.0%	$29.87	—	COM	50107A104