Casdin Capital, LLC Diversified Active

CIK: 0001534261 · Show all filings

Period: Q3 2024 (← Previous) (Next →)

Filing Date: Nov 14, 2024

Total Value ($000): $1,499,957 (100.0% shares, 0.0% debt)

Holdings (35)

BLFS BIOLIFE SOLUTIONS INC 14.5%

Value ($000) $218,027 Shares 8,707,165 Est. Cost $19.43 Unrealized +21.6%

RVMD REVOLUTION MEDICINES INC 12.4%

Value ($000) $186,583 Shares 4,114,283 Est. Cost $25.89 Unrealized +68.2%

WGS GENEDX HOLDINGS CORP 9.9%

Value ($000) $148,844 Shares 3,507,164 Est. Cost $9.11 Unrealized +270.6%

LAB STANDARD BIOTOOLS INC 9.2%

Value ($000) $137,522 Shares 71,254,677 Est. Cost $2.36 Unrealized -17.1%

SRPT SAREPTA THERAPEUTICS INC 8.9%

Value ($000) $134,069 Shares 1,073,500 Est. Cost $100.84 Unrealized +37.1%

ILMN ILLUMINA INC 6.5%

Value ($000) $97,808 Shares 750,000 Est. Cost $119.44 Unrealized +3.3%

RNAM AVIDITY BIOSCIENCES INC 6.4%

Value ($000) $95,757 Shares 2,084,841 Est. Cost $14.11 Unrealized +207.6%

RLAY RELAY THERAPEUTICS INC 4.4%

Value ($000) $65,498 Shares 9,251,108 Est. Cost $19.94 Unrealized -62.5%

ALNY ALNYLAM PHARMACEUTICALS INC 3.1%

Value ($000) $46,755 Shares 170,000 Est. Cost $138.08 Unrealized +88.6%

EXAS EXACT SCIENCES CORP 3.0%

Value ($000) $44,278 Shares 650,000 Est. Cost $74.77 Unrealized -24.5%

NTLA INTELLIA THERAPEUTICS INC 2.7%

Value ($000) $41,100 Shares 2,000,000 Est. Cost $37.51 Unrealized -38.5%

GPCR STRUCTURE THERAPEUTICS INC 2.0%

Value ($000) $30,723 Shares 700,000 Est. Cost $33.80 Unrealized —

— BLUEPRINT MEDICINES CORP 2.0%

Value ($000) $30,190 Shares 326,378 Est. Cost $3820.05 Unrealized —

DNLI DENALI THERAPEUTICS INC 1.9%

Value ($000) $28,839 Shares 990,000 Est. Cost $29.48 Unrealized -15.9%

CDXS CODEXIS INC 1.7%

Value ($000) $24,948 Shares 8,100,000 Est. Cost $2.87 Unrealized +7.9%

VCYT VERACYTE INC 1.5%

Value ($000) $22,681 Shares 666,308 Est. Cost $24.40 Unrealized +15.3%

NGNE NEUROGENE INC 1.5%

Value ($000) $22,013 Shares 524,616 Est. Cost $14.32 Unrealized +170.8%

— VERVE THERAPEUTICS INC 1.3%

Value ($000) $19,339 Shares 3,995,571 Est. Cost $36.00 Unrealized —

BEAM BEAM THERAPEUTICS INC 1.3%

Value ($000) $18,988 Shares 775,000 Est. Cost $49.33 Unrealized -47.6%

TNYA TENAYA THERAPEUTICS INC 0.9%

Value ($000) $12,995 Shares 6,732,971 Est. Cost $12.86 Unrealized -78.1%

FDMT 4D MOLECULAR THERAPEUTICS IN 0.8%

Value ($000) $12,432 Shares 1,150,000 Est. Cost $16.94 Unrealized -2.0%

— 2SEVENTY BIO INC 0.6%

Value ($000) $9,440 Shares 2,000,000 Est. Cost $9.15 Unrealized —

TNGX TANGO THERAPEUTICS INC 0.6%

Value ($000) $9,150 Shares 1,188,349 Est. Cost $5.87 Unrealized +62.5%

SNDX SYNDAX PHARMACEUTICALS INC 0.6%

Value ($000) $9,144 Shares 475,000 Est. Cost $18.99 Unrealized +8.8%

GH GUARDANT HEALTH INC 0.5%

Value ($000) $8,029 Shares 350,000 Est. Cost $26.87 Unrealized +5.3%

CTNM CONTINEUM THERAPEUTICS INC 0.4%

Value ($000) $5,678 Shares 296,666 Est. Cost $16.10 Unrealized +19.1%

IPSC CENTURY THERAPEUTICS INC 0.4%

Value ($000) $5,493 Shares 3,212,316 Est. Cost $16.88 Unrealized -88.4%

GRAL GRAIL INC 0.3%

Value ($000) $4,816 Shares 350,000 Est. Cost $15.40 Unrealized -1.6%

ABSI ABSCI CORPORATION 0.2%

Value ($000) $3,718 Shares 973,260 Est. Cost $19.41 Unrealized -79.5%

PACB PACIFIC BIOSCIENCES CALIF IN 0.1%

Value ($000) $1,761 Shares 1,035,859 Est. Cost $11.43 Unrealized -85.6%

PRME PRIME MEDICINE INC 0.1%

Value ($000) $1,421 Shares 367,175 Est. Cost $18.06 Unrealized -74.4%

— EXSCIENTIA PLC 0.1%

Value ($000) $1,044 Shares 213,900 Est. Cost $19.76 Unrealized —

GLUE MONTE ROSA THERAPEUTICS INC 0.0%

Value ($000) $456 Shares 86,014 Est. Cost $20.37 Unrealized -75.2%

DNA GINKGO BIOWORKS HOLDINGS INC 0.0%

Value ($000) $297 Shares 36,493 Est. Cost $10.02 Unrealized 0.0%

— KRONOS BIO INC 0.0%

Value ($000) $124 Shares 123,839 Est. Cost $29.87 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
BLFS	BIOLIFE SOLUTIONS INC	8,707,165	$218,027	14.5%	$19.43	+21.6%	COM NEW	09062W204
RVMD	REVOLUTION MEDICINES INC	4,114,283	$186,583	12.4%	$25.89	+68.2%	COM	76155X100
WGS	GENEDX HOLDINGS CORP	3,507,164	$148,844	9.9%	$9.11	+270.6%	COM CL A	81663L200
LAB	STANDARD BIOTOOLS INC	71,254,677	$137,522	9.2%	$2.36	-17.1%	COM	34385P108
SRPT	SAREPTA THERAPEUTICS INC	1,073,500	$134,069	8.9%	$100.84	+37.1%	COM	803607100
ILMN	ILLUMINA INC	750,000	$97,808	6.5%	$119.44	+3.3%	COM	452327109
RNAM	AVIDITY BIOSCIENCES INC	2,084,841	$95,757	6.4%	$14.11	+207.6%	COM	05370A108
RLAY	RELAY THERAPEUTICS INC	9,251,108	$65,498	4.4%	$19.94	-62.5%	COM	75943R102
ALNY	ALNYLAM PHARMACEUTICALS INC	170,000	$46,755	3.1%	$138.08	+88.6%	COM	02043Q107
EXAS	EXACT SCIENCES CORP	650,000	$44,278	3.0%	$74.77	-24.5%	COM	30063P105
NTLA	INTELLIA THERAPEUTICS INC	2,000,000	$41,100	2.7%	$37.51	-38.5%	COM	45826J105
GPCR	STRUCTURE THERAPEUTICS INC	700,000	$30,723	2.0%	$33.80	—	SPONSORED ADS	86366E106
—	BLUEPRINT MEDICINES CORP	326,378	$30,190	2.0%	$3820.05	—	COM	09627Y109
DNLI	DENALI THERAPEUTICS INC	990,000	$28,839	1.9%	$29.48	-15.9%	COM	24823R105
CDXS	CODEXIS INC	8,100,000	$24,948	1.7%	$2.87	+7.9%	COM	192005106
VCYT	VERACYTE INC	666,308	$22,681	1.5%	$24.40	+15.3%	COM	92337F107
NGNE	NEUROGENE INC	524,616	$22,013	1.5%	$14.32	+170.8%	COM	64135M105
—	VERVE THERAPEUTICS INC	3,995,571	$19,339	1.3%	$36.00	—	COM	92539P101
BEAM	BEAM THERAPEUTICS INC	775,000	$18,988	1.3%	$49.33	-47.6%	COM	07373V105
TNYA	TENAYA THERAPEUTICS INC	6,732,971	$12,995	0.9%	$12.86	-78.1%	COM	87990A106
FDMT	4D MOLECULAR THERAPEUTICS IN	1,150,000	$12,432	0.8%	$16.94	-2.0%	COM	35104E100
—	2SEVENTY BIO INC	2,000,000	$9,440	0.6%	$9.15	—	COMMON STOCK	901384107
TNGX	TANGO THERAPEUTICS INC	1,188,349	$9,150	0.6%	$5.87	+62.5%	COM	87583X109
SNDX	SYNDAX PHARMACEUTICALS INC	475,000	$9,144	0.6%	$18.99	+8.8%	COM	87164F105
GH	GUARDANT HEALTH INC	350,000	$8,029	0.5%	$26.87	+5.3%	COM	40131M109
CTNM	CONTINEUM THERAPEUTICS INC	296,666	$5,678	0.4%	$16.10	+19.1%	CL A	21217B100
IPSC	CENTURY THERAPEUTICS INC	3,212,316	$5,493	0.4%	$16.88	-88.4%	COM	15673T100
GRAL	GRAIL INC	350,000	$4,816	0.3%	$15.40	-1.6%	COM	384747101
ABSI	ABSCI CORPORATION	973,260	$3,718	0.2%	$19.41	-79.5%	COM	00091E109
PACB	PACIFIC BIOSCIENCES CALIF IN	1,035,859	$1,761	0.1%	$11.43	-85.6%	COM	69404D108
PRME	PRIME MEDICINE INC	367,175	$1,421	0.1%	$18.06	-74.4%	COM	74168J101
—	EXSCIENTIA PLC	213,900	$1,044	0.1%	$19.76	—	ADS	30223G102
GLUE	MONTE ROSA THERAPEUTICS INC	86,014	$456	0.0%	$20.37	-75.2%	COM	61225M102
DNA	GINKGO BIOWORKS HOLDINGS INC	36,493	$297	0.0%	$10.02	0.0%	CL A NEW	37611X209
—	KRONOS BIO INC	123,839	$124	0.0%	$29.87	—	COM	50107A104